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21 Postdoctoral Fellowships at Moffitt Cancer Center, Florida

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Are you holding PhD degree and looking for Postdoctoral Fellowships? Moffitt Cancer Center, Florida invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.

1. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Mann lab is dedicated to uncovering novel mechanisms driving pancreatic cancer (PDAC) progression and relapse. Alternative splicing is a process critical to cancer development and mechanisms deregulating splicing during disease progression is an exciting and emerging new area of study in PDAC biology. We recently showed that downregulation of the RNA binding protein RBFOX2 promotes PDAC metastasis through alternative splicing that enhances cytoskeletal remodeling programs promoting cell migration and invasion (Maurin et al., Nature Communications 2023). We are currently dissecting the mechanisms by which RBFOX2-mediated splicing events enhance the oncogenic function of proteins to promote PDAC progression. 

Application Deadline: Open Until Filled

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2. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Applications are being sought for the position of Postdoctoral Fellow to work under the supervision of Dr. Jeffrey West on inter-disciplinary projects involving evolutionary game theory approaches to design Evolutionary Therapy treatment protocols in breast cancer. We are seeking a talented scientist to work within the unique, multi-disciplinary, and collaborative environment of the Integrated Mathematical Oncology (IMO) department. IMO participates in various integrative projects with mathematicians, evolutionary biologists, experimentalists, and clinical oncologists to develop analytical and predictive approaches to cancer treatment.

Application Deadline: Open Until Filled

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3. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Issam El Naqa’s lab seeks to hire a post-doctoral fellow to join the tremendous opportunities to do cutting-edge research in his lab and develop a stellar career in the emerging domain of machine learning in cancer. The specific project will be related to developing machine learning algorithms for cancer diagnosis and response modeling using molecular and imaging data (pan-omics) with new deep, generative AI, and reinforcement learning approaches.

Application Deadline: Open Until Filled

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4. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Markowitz lab seeks a Postdoc Fellow whose skills and professional experience have prepared them to contribute to our commitment to diversity and excellence. The lab’s research interest is in studying the role of nitric oxide in mediating responses to checkpoint blockade and other melanoma therapies. We are also developing tools to predict which patients will likely fail immune-based therapy via novel high dimensional flow cytometry, mass spectrometry, and informatics techniques, allowing those patients to be treated with other potentially more effective therapies. We are a translational laboratory striving to translate the knowledge gained in the laboratory via immune-based and traditional biochemical approaches to the clinic. 

Application Deadline: Open Until Filled

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5. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The research interest of the lab is to study the structures, regulation, and therapeutic targeting of p53 tumor suppressor pathway for cancer treatment. Ongoing work involves development of novel PROTACs, targeting of temperature-sensitive mutant p53, transcription potential of mutant p53, MDMX regulation of Wnt signaling.

Application Deadline: Open Until Filled

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6. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Clinical Fellow is an employee who is in a Moffitt sponsored fellowship training program with the focus to advance their knowledge of a specific specialty of medical or surgical patient care. The Clinical Fellow works under the supervision of a physician faculty member in accordance with the scope of practice and the educational goals and objectives detailed in the training program documentation, any applicable subspecialty accreditation requirements and approved by the Graduate Medical Education Committee of Moffitt Cancer Center. The Clinical Fellow will abide by all applicable Hospital policies, Code of Ethics, procedures, and Medical Staff Bylaws.

Application Deadline: Open Until Filled

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7. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow position is opening in the Clinical Science lab of Dr. Arnold Etame located within the Stabile Research Building at the Moffitt Cancer Center & Research Institute, a world-class NCI-designated Comprehensive Cancer Center. The Etame Lab applies an interdisciplinary approach that integrates use of cancer/cell biological methods, drug and CRISPR screens, mouse models, bioinformatics, and imaging tools to study glioblastoma in vitro and in vivo. 

Application Deadline: Open Until Filled

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8. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Jiang Lab (https://lab.moffitt.org/jiang/ ) in the Department of Molecular Oncology is now recruiting postdoctoral fellows. Research in our lab sits at the interface of redox biology, metabolism and signaling, and focuses on understanding the role of antioxidant systems in cancer therapy resistance. We combine frontier molecular, genomic, proteomic, and metabolic approaches to address these questions.

Application Deadline: Open Until Filled

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9. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The research in Dr. Wan’s lab is focused on protein post-translational modifications, including ubiquitination, acetylation, methylation, and phosphorylation. We are interested in understanding how these modifications are misregulated in tumor cells, tumor-infiltrating immune cells, and tumor-interacting stroma cells. We are also interested in developing next-generation techniques to characterize these modifications. Our current projects include the multifaceted roles of ITCH in melanoma and the melanoma immune microenvironment, the context-dependent functions of master cell cycle regulator APC/C in breast cancer and ovarian cancer, the crosstalk between tumor cell aneuploidy and innate immunity, and several others.

Application Deadline: Open Until Filled

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10. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Dunne Lab combines expertise in cell therapy, biomaterials, drug delivery, immunology, and medical imaging in order to develop novel cancer treatment strategies. The lab’s primary research focus is engineering micro- and nano-scale drug carriers for the purpose of controlling immune cell phenotype in order to alter the immunological state of the tumor microenvironment and ultimately enhance the efficacy of cell therapies for the treatment of cancer. Understanding temporal changes in whole body and intratumoral distribution of cell therapies and drug carriers is fundamental to this research. We are further interested in understanding the effect of externally applied stimuli (e.g. radiotherapy and/or hyperthermia) on the distribution kinetics of therapeutic agents.

Application Deadline: Open Until Filled

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11. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Oskarsson laboratory studies the molecular interactions between cancer cells and the microenvironment in metastasis and in response to therapeutic intervention. The molecular context generated by the metastatic microenvironment evolves with progression of the disease and is an important determinant of cancer cell fitness. Our objective is to dissect both cellular and extracellular matrix (ECM) components of the microenvironment in metastasis. The group has shown how stress signals induced by chemotherapy can promote the induction of specific ECM components resulting in generation of a metastatic niche that can limit therapeutic efficacy (Insua-Rodriguez et al EMBO Molecular Medicine 2018). The work of the group has also revealed novel pro-metastatic interactions of disseminated cancer cells with fibroblasts and with endothelial cells in the lungs (Pein et al Nature Communications 2020 and Hongu et al. Nature Cancer 2022). Ongoing work involves the characterization of disseminated cancer cells that are dormant in different visceral organs but maintain growth potential.

Application Deadline: Open Until Filled

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12. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Erin George is a surgeon-scientist and Assistant Member in the Department of Gynecologic Oncology with a secondary appointment in Drug Discovery at Moffitt Cancer Center. Dr. George has completed a Bachelor of Science in Biomedical Engineering, a Medical Degree, and an Obstetrics and Gynecology Residency at Columbia University followed by a Gynecologic Oncology fellowship at the University of Pennsylvania (Penn) most recently in 2018, with nearly a decade of experience with preclinical models in ovarian cancer, in particular, the orthotopic patient derived xenograft (PDX) models. Dr. George is a PI on a targeted tissue collection protocol in ovarian cancer (MCC 22609) and building a repertoire of orthotopic PDX models as well as microtumor explants in a novel culture system. The George lab is currently working closely with collaborators in Drug Discovery (high throughput drug screen, chemical proteomics) and BioEngineering (novel ex vivo culture system, advanced live imaging, single cell sampling) with the goal of bringing novel targeted treatment approaches to patients via phase I/II clinical trials.

Application Deadline: Open Until Filled

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13. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The laboratories of Drs. Kenneth Shain, Mehdi Damaghi and Ariosto Silva, at MCC, are seeking highly motivated candidates for postdoctoral training in the field of bioinformatics, computational biology, cancer genomics and evolutionary theory of cancer, to work on a cutting-edge, interdisciplinary, and cross-institutional research, focused on the co-evolution and cancer epigenome, throughout tumor progression, with a particular emphasis on Multiple Myeloma (led by Dr. Shain) and Breast Cancer (led by Dr. Damaghi). Drs. Shain, Damaghi and Silva research focuses on development of multi-omics model of carcinogenesis and evolution of drug resistance in cancer, as well as innovative approaches to delay and/or reverse these dynamics, with the goal of improving patient’s quality of life and survival. The research involves a tight collaboration with the laboratory of Dr. Eugene Koonin at the National Center for Biotechnology Information (NCBI). The successful candidate will work with basic, translational, and clinical scientists at Moffitt and NCBI, in a synergistic collaboration, and will hold a fellowship at the NIH/NLM/NCBI.

Application Deadline: Open Until Filled

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14. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The lab of Dr. Paulo Rodriguez at the Moffitt Cancer Center seeks to recruit Postdoctoral Fellow to join his team. Dr. Rodriguez’s research programs focus on the understanding of the cellular and molecular mechanisms that control leukocyte dysfunction in tumors, with a focus on T cells and myeloid cells, and the central metabolic programs regulating immunity in cancer. The long-term goal of his research is to develop new therapeutic strategies that restore protective immunity in cancer, leading to long lasting anti-tumor T cell immunity.

Application Deadline: Open Until Filled

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15. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Research in the DeNicola lab is centered around how metabolic deregulation occurs during tumorigenesis and how mutations that promote the activation of the transcription factor NRF2 control this process. Recent work from our lab has focused on how NRF2 influences tumor initiation and progression (PMID: 37062029), how NRF2 influences the cellular responses to cysteine availability (PMID: 31107239 and 33357455), and how tissues and compartments meet their demand for cysteine (PMID: 36862034, bioRxiv 2022.10.06.511221). We have several exciting projects focused on understanding how tissues and tumors use and acquire cysteine and rewire their metabolism in response to oncogene activation, stress, and metabolic perturbation. We are recruiting a postdoctoral fellow eager to explore these topics with sophisticated animal models, in vivo tracing and mass spec metabolomics technologies, and leverage these resources and technologies to develop their own independent research program.

Application Deadline: Open Until Filled

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16. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A fully funded postdoctoral position is available in the laboratory of Florian A. Karreth, PhD in the Department of Molecular Oncology at Moffitt Cancer Center in Tampa, FL. The Karreth lab studies the molecular and genetic mechanisms promoting melanoma progression, metastasis, and drug resistance. We are recruiting a postdoctoral fellow to work on glycol-RNA at the intersection of glycobiology and RNA biology in the context of melanoma. This project is funded by the Department of Defense and will involve the characterization of glycoRNA formation and function and their role in mediating melanoma progression and metastasis by affecting interactions with the tumor microenvironment and immune system. 

Application Deadline: Open Until Filled

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17. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Padron Lab studies the molecular pathogenesis of Chronic Myelomonocytic Leukemia (CMML) with the goal of identifying novel therapeutic vulnerabilities. CMML is a rare and lethal hematopoietic malignancy characterized by a characteristic classical monocytosis and a propensity to transform to Acute Myeloid Leukemia (AML). Interestingly, the majority of CMML patients present in a clinically asymptomatic state for periods of weeks to months before progressing to a lethal disease that clinically manifests via a heterogenous group of symptoms. There are no FDA approved therapies that have been demonstrated to alter the natural history of disease and the goal of our laboratory is to provide the preclinical evidence to increase the armamentarium available to clinicians treating this disease. Although our focus is centrally on CMML, our work aims to address questions in the field that can be more broadly applicable to other types of leukemias and cancers.

Application Deadline: Open Until Filled

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18. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Integrated Program in Cancer and Data Science (ICADS) at Moffitt serves to train the next generation of leaders in Cancer and Data Science. Over thirty faculty members, who work together at the interface of cancer research and data science, serve as mentors and co-mentors. The program is cross-disciplinary, spanning every Division at Moffitt including: 1) basic science; 2) population science; 3) clinical science; 4) translational science; and 5) quantitative science. Postdoctoral trainees in the program are paired into training teams that design a mentored research project that addresses a critical issue in cancer utilizing data science approaches (e.g., biostatistics, statistical genomics, bioinformatics). In addition to research, the Program includes structured coursework, taken as appropriate, and is supplemented by participation in many career development activities. 

Application Deadline: Open Until Filled

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19. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Patrick Hwu’s lab at the Moffitt Cancer Center in Tampa, Florida is seeking a highly motivated Postdoc to join his multi-disciplinary laboratory team focused on understanding the underlying mechanisms of cancer-immune system interactions and developing novel translational cellular immunotherapies with the goal to improve current treatments for cancer patients. Dr. Hwu’s research is engaged in developing innovative immunotherapy approaches to trigger potent adaptive antitumor immunity to overcome resistance to cancer immunotherapy. His studies are focused on gene-modified T-cells, development of translational combinatorial therapies which include immune checkpoint blockade and adoptive T-cell therapy, and identification of targetable T-cell molecules to boost the proliferation, migration and function of tumor reactive T-cells.

Application Deadline: Open Until Filled

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20. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Applications for a Postdoctoral Fellow position are being accepted now in the computational lab of Dr. Kasia Rejniak (https://moffitt.org/research-science/researchers/katarzyna-rejniak/ ) on an exciting NCI-funded interdisciplinary research project in mathematical modeling of breast ductal carcinoma in situ and breast cancer micro invasions. We seek talented individuals with a Ph.D. and background in applied mathematics, computer sciences, physics, or other computational disciplines to work in close collaboration with cancer biologists and clinicians within a unique research environment of the Integrated Mathematical Oncology (IMO) Department.

Application Deadline: Open Until Filled

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21. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The research in Dr. Wan’s lab is focused on protein post-translational modifications, including ubiquitination, acetylation, methylation, and phosphorylation. We are interested in understanding how these modifications are misregulated in tumor cells, tumor-infiltrating immune cells, and tumor-interacting stroma cells. We are also interested in developing next-generation techniques to characterize these modifications. Our current projects include the multifaceted roles of ITCH in melanoma and the melanoma immune microenvironment, the context-dependent functions of master cell cycle regulator APC/C in breast cancer and ovarian cancer, the crosstalk between tumor cell aneuploidy and innate immunity, and several others.

Application Deadline: Open Until Filled

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