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19 Postdoctoral Fellowships at Roswell Park Comprehensive Cancer Center, Buffalo, New York

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Are you holding PhD degree and looking for Postdoctoral Fellowships? Roswell Park Comprehensive Cancer Center, Buffalo, New York invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.

1. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Identification and Functional Analysis of Novel Genetic Interactions and Vulnerabilities in KRAS Mutant Solid Tumors. The Cancer Genetics and Genomics Department at Roswell Park Cancer Institute is searching for an ambitious PhD biologist for a postdoctoral research project in the Identification and Functional Analysis of Novel Genetic Interactions and Vulnerabilities in KRAS Mutant Solid Tumors. Projects will be oriented around one or some combinations of the following topics: identification and characterization of novel tumor suppressor genes and/or oncogenes; and the study of their dysfunction mechanisms (focusing on epigenetics and tumor metabolism) in lung cancer and/or pancreatic cancer (e.g., using cell culture, animal models). Genomic screening using custom lentiviral CRISPR or other small RNA libraries in xenograft models.

Application Deadline: Open Until Filled

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2. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Applications are sought for a Post-Doctoral or Research Associate position in the Department of Cancer Prevention and Control at Roswell Park Comprehensive Cancer Center. The candidate will take part in NIH-funded projects on HPV infection and related diseases in high-risk populations. Projects include a large HPV vaccine surveillance study of inner-city minority youth, and a prospective study of oral HPV and the microbiome in HIV+ individuals. The candidate is expected to analyze data, publish papers, assist with preparing grants, and help supervise graduate and undergraduate students. The position will be for a period of 2 years, with possibility of extension, and comes with a competitive salary and attractive benefits.

Application Deadline: Open Until Filled

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3. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our laboratory studies and develops adoptive T cell therapies targeting solid tumors. The postdoctoral scientist will focus on developing genetically engineered T cells starting from the molecular cloning phase of cell therapy development, and then advancing to preclinical in vitro work and clinically relevant mouse models. A strong background in immunology and molecular biology will allow the successful applicant to be creative within the lab, enhancing T cell function and tumor targeting for optimal patient translation and high impact publication. The postdoctoral scientists will work within the Center for Immunotherapy, which holds multiple institutional level grants and houses multiple investigators ‚Äď including immunologists, molecular biologists, and computational biologists – dedicated to developing immunetherapies. Strong support for career development and academic and educational activities are included.¬†

Application Deadline: Open Until Filled

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4. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Position #1 is focused on studying the role of retinoblastoma tumor suppressor pathway (RB, p16ink4a, and cyclin D1) in breast cancer. Specific emphasis will be placed on the role of RB loss in disease progression and therapeutic response. This work will incorporate the use of cell culture, animal models, and clinical specimens.
Position #2 is focused on deciphering mechanisms through which breast cancers evade standard therapies and elucidate new approaches for therapeutic intervention using targeted approaches. These studies will use PDX, organoid, and mouse models.

Application Deadline: Open Until Filled

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5. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our laboratory is broadly interested in transcriptional regulation and cell-fate determination in cancer cell biology and treatment. We are seeking a highly motivated and skilled candidate to work on a novel family of transcriptional and cell-fate regulators in cancer cell biology and treatment response, and stem cell biology. The candidate will be surrounded by a stimulating research environment, cutting-edge technology, and daily interactions with colleagues in other labs. The training environment will be one where regular discussion of new ideas, and freedom to explore new avenues of investigation, will be encouraged.

Application Deadline: Open Until Filled

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6. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A research group at Roswell Park Comprehensive Cancer Center Department of Cancer Prevention and Control (Buffalo, NY) is looking for a postdoctoral research fellow, who is interested in academic research of cancer epidemiology, genomics, and cancer health disparities. The group is dedicated to cutting-edge population-based research to understand the biological underpinnings of cancer racial/ethnic disparities, with multiple active federal and private foundation funded research projects focusing on genomic, molecular, and cellular mechanisms underlying cancer health disparities in several large and unique racial/ethnic minority populations, as well as on cancer outcome and survivorship. 

Application Deadline: Open Until Filled

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7. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoc position is immediately available to study the biology of acute leukemia and perform preclinical evaluation of promising therapeutic approaches for acute leukemia. Candidates should be highly motivated and able to work independently in designing, performing, and analyzing experiments. Experience in data presentation (oral/poster) and writing skills are highly desired. Proficiency in laboratory skills includes flow cytometry, fluorescent microscopy, in vitro proliferation/cytotoxicity assays, western blots, RNA/DNA extraction and other molecular biology techniques are required. Candidates with prior experience working on tumor mouse models are preferred (but not required).

Application Deadline: Open Until Filled

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8. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral position is open for a highly motivated candidate in the laboratory of Dr. AJ Robert McGray in the Department of Immunology. The project will focus on developing and optimizing strategies for the delivery of immune cell engagers (e.g. BiTEs) targeting the tumor and/or tumor stroma as potent cancer immunotherapies. The selected individual will use both in vitro systems and in vivo mouse models to develop, validate, and therapeutically test immune cell engagers. While a primary focus of this research will be to develop therapies that can be translated clinically to treat ovarian cancer, projects are anticipated to be broadly applicable to other tumor indications and will involve parallel studies in other disease areas. 

Application Deadline: Open Until Filled

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9. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Department of Pediatric Oncology is seeking a full time Postdoctoral Fellow in the laboratory of Dr. Nataliya Buxbaum. The Buxbaum lab focuses on immunometabolism as it relates to hematopoietic stem cell transplantation (HSCT) and cellular immunotherapies. Our bench-to-bedside laboratory and clinical investigations are centered on graft-versus-host disease (GvHD) with a goal of developing new imaging and therapeutic modalities for this condition (Assmann, J.C. et al. Blood, 2021 https://pubmed.ncbi.nlm.nih.gov/32785680/; Mhandire, K. et al. Metabolites, 2021 https://www.mdpi.com/2218-1989/11/11/736; Buxbaum, NP, et al. Journal of Clinical Investigation Insight, 2017 https://insight.jci.org/articles/view/92851).

Application Deadline: Open Until Filled

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10. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Goodrich lab at Roswell Park Comprehensive Cancer Center is looking for a highly motivated postdoctoral fellow to study prostate cancer lineage plasticity (see Ku et al. Science 2017, Mu et al. Science 2017, Pearson et al. Cancer Cell, 2021). The postdoc will work with a dynamic team of clinicians and scientists to perform both pre-clinical experiments and clinical trial correlative studies aimed at both understanding mechanisms underlying prostate cancer lineage plasticity and targeting them for therapeutic benefit. 

Application Deadline: Open Until Filled

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11. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are seeking an enthusiastic and talented candidate with a Ph.D. in cancer biology, genetics, molecular biology, experimental therapeutics, bioinformatics or related field.

  • Perform a variety of routine and specialized lab tests and experimental procedures.
  • Have access to patient database, tissue specimen, cell culture, patient-derived xenograft, next-generation sequencing and genetic mouse model.
  • Assist with writing animal and human trial protocols, manuscripts, and grants.

Application Deadline: Open Until Filled

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12. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The laboratory of Dr. Marco Davila in the Department of Medicine is looking for a postdoctoral candidate to work on a research project aiming to generate novel chimeric antigen receptor (CAR) T cells specifically targeted to antigens for the treatment of cancer. The specific research project involves the usage and identification of antigens for targeted cell therapies, CAR design, and experimental models to validate antitumor capacity. The selected individual will perform studies using in vitro models to validate and enhance the ability of CAR T cells to be used as effective cell therapy. The experiments will also involve the analyses of immune cell functions and mouse models of cancer. 

Application Deadline: Open Until Filled

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13. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The laboratory of Dr. Andrew Goey is looking for a highly motivated and clinically oriented postdoctoral fellow to work on improving cancer treatments by pharmacogenetics. Research that will be carried out is highly translational and include genetic association studies, clinical trials, and in vitro drug metabolism experiments. The preferred candidate will have a track record of publications in the fields of pharmacogenetics and clinical pharmacology. Expected duties of the postdoctoral fellow include management and conduct of pharmacogenetic research projects, assistance in writing manuscripts, mentoring junior lab members, and applying for independent fellowship funding.

Application Deadline: Open Until Filled

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14. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Liu lab (https://www.roswellpark.org/xuhang-liu) at the Department of Pharmacology and Therapeutics at Roswell Park Comprehensive Cancer Center is seeking highly-motivated postdoctoral fellows with interests in RNA and/or cancer biology to join our efforts in fighting cancer. We employ a multi-disciplinary approach that combines in vivo mouse models, in vitro patient-derived organoids (PDOs), classical biochemistry, cutting-edge multi-omics techniques, and advanced bioinformatic analyses to discover key post-transcriptional mechanisms that govern cancer progression and metastasis. We aim to develop innovative therapeutic strategies­­, in particular RNA therapeutics, to translate these mechanistic insights into the clinic.

Application Deadline: Open Until Filled

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15. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral position is available in the Atanassov Lab in the Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, New York. We are looking for a highly motivated, self-driven postdoctoral fellow to study the role of deubiquitinating enzymes (DUBs) in cancer. The postdoctoral fellow will work with a dynamic team of scientists and research fellows in an outstanding research environment and utilize genetically engineered mouse models and biochemical approaches to elucidate the molecular mechanisms of how DUB functions potentiate cancer growth and develop strategies for their therapeutic targeting. The study is supported by NIH funded R01 award, and the position is ready for an immediate start.

Application Deadline: Open Until Filled

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16. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Das lab at Roswell Park Comprehensive Cancer Center is looking for a highly motivated postdoctoral fellow with a passion for research to study molecular mechanisms of breast cancer with emphasis on the crosstalk between estrogen receptors and p53 signaling. Translating lab findings to novel therapies will be a priority (see Mukhopadhyay et al. Journal of the National Cancer Institute (JNCI) 2019, Oturkar et al. Cancers 2022, Scarpetti et al. The Oncologist 2023).

Application Deadline: Open Until Filled

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17. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Postdoctoral positions are available in the laboratory of Dr. Dhyan Chandra, Pharmacology and Therapeutics. New postdoctoral fellows will study the role of mitochondria and heat shock proteins in prostate cancer biology and the development of therapeutic resistance in cancer. 

Application Deadline: Open Until Filled

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18. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Department of Immunology at Roswell Park invites applications for a postdoctoral fellowship position. The applicant should possess research experience in molecular biology and tumor immunology. We have established several mouse tumor models in which to investigate key concepts of host-tumor interactions, including (a) the biology or molecular biology of tumor progression; (b) host or immune determinants that additionally influence and drive the neoplastic process, such as immune suppressive myeloid populations; and (c) the development of novel combination immunotherapy strategies that target or modulate such host or neoplastic events to improve antitumor efficacy in these preclinical models.

Application Deadline: Open Until Filled

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19. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our laboratory studies and develops adoptive T cell (CAR T cell) therapies targeting solid tumors. The postdoctoral scientist will develop genetically engineered T-cell therapies starting from the molecular cloning phase of cell therapy development, and then advancing to preclinical in vitro work and clinically relevant mouse models. A strong background in molecular biology and immunology will allow the successful applicant to be creative within the lab, enhancing T cell function and tumor targeting for optimal patient translation and high-impact publication. The postdoctoral scientist will work under the co-mentorship of Leonid Cherkassky and Renier Brentjens. We have a rapidly advancing program engaged in cutting-edge preclinical science and are supported by a strong institutional commitment to translating cellular therapies to cancer patients.

Application Deadline: Open Until Filled

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