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12 Fully Funded PhD Programs at Karolinska Institutet, Sweden

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Are you holding Master’s degree and looking for fully funded PhD positions? Karolinska Institutet, Sweden invites online application for multiple funded PhD Programs / fully funded PhD positions in various research areas.

Candidates interested in fully funded PhD positions can check the details and may apply as soon as possible. Interested and eligible applicants may submit their online application for PhD programs via the University’s Online Application Portal. 

1. Fully Funded PhD Position in Exploring the role of cell size on aging of human hematopoietic stem cells

Summary of PhD Program:

We are seeking a highly motivated and ambitious individual from universities around the world to join the research team of Assistant Professor Dr. Jette Lengefeld as a PhD Researcher to mechanistically understand novel mechanisms of human stem cells that drive aging and disease. The Lengefeld research group uses hematopoietic stem cells from mice and human bone marrow donations to discover how deregulation of cellular size is connected to aging and cancer.

Application Deadline: 15.Jan.2024

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2. Fully Funded PhD Position in cardiovascular research

Summary of PhD Program:

The aim of this project is to characterize the function of red blood cell-derived factors in the development of vascular dysfunction in type 2 diabetes and study the role of hypoxia in the communication of the red blood cell and vascular dysfunction. Studies are designed using a combination of clinically-based and molecular/biochemical methods. Samples from well-characterized patients with type 2 diabetes, rodent diabetic models, gene-modified mouse models and cell models are used. Research projects involve in vitro (including isolation of red blood cells, extracellular vesicles and animal tissues, cell culture, immunohistochemistry, Western blot and qPCR), ex vivo (vessel reactivity assessment with Wire myograph) and in vivo experimental methods (including rat and mouse work).

Application Deadline: 09.Jan.2024

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3. Fully Funded PhD Position in Computational radiation neurobiology

Summary of PhD Program:

Our research group has been involved in seminal works describing the effects of ionising radiation in the juvenile brain and using lithium (among other drugs and therapeutics strategies) to minimise these effects. Regarding lithium, we have shown that it protects the brain from acute radiation injuries without protecting or promoting the growth of the malignant cells (Cancer Research, 2006; Oncotarget, 2017), even when administered long after cranial irradiation (Molecular Psychiatry, 2021). Moreover, lithium prevents radiation-induced cognitive deficits (Molecular Psychiatry, 2021; Molecular and Cellular Neuroscience, 2012) and increases the hippocampal proliferation of the neural stem and progenitor cells (Journal of Cerebral Blood Flow and Metabolism, 2013; Oncotarget, 2015; Frontiers in Molecular Neuroscience, 2018).

Application Deadline: 07.Jan.2024

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4. Fully Funded PhD Position in translational melanoma research

Summary of PhD Program:

We are seeking a highly motivated and talented Ph.D. student to join our research group. We are looking for a doctoral student who is curious and eager to solve biological questions with focus on translational melanoma research and a profound interest in immune-oncology. Specifically, for the doctoral project the research aims at improving melanoma immune-based treatments by understanding differences in therapy responses on the molecular and cellular levels. The overall goal is to translate our lab research into a clinical trial.

Application Deadline: 22.Dec.2023

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5. Fully Funded PhD Position in Mechanotransduction and UPS on Skeletal Muscle Atrophy

Summary of PhD Program:

The main project is to discover, test, and confirm key factors controlling mechanotransduction and proteasomal activity that are involved in the regulation of skeletal muscle mass and function, and to investigate whether these factors can be modulated by countermeasures, such as exercise, in humans. The successful candidate will work primarily with cell models, but will also use skeletal muscle tissue from humans and mice. The student will then use molecular, functional, and phenotypic data to translate the findings of the project into the discovery of relevant mechanotransduction and proteasomal factors that control unloading/disuse induced skeletal muscle alterations. Therefore, we are looking for highly motivated students with a strong background in cell biology and a genuine interest in skeletal muscle physiology.

Application Deadline: 15.Dec.2023

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6. Fully Funded PhD Position in computational and experimental neuroscience

Summary of PhD Program:

The project is focused on increased understanding of our working memory, an integral part of flexible cognition. To this end, human cognitive and neuroimaging studies will be combined with new analysis techniques and machine learning. In particular, the underlying mechanisms that lend humans their ability to seamlessly utilize their working memory in dynamic settings will be investigated in this project. The student will conduct multiple studies, both using EEG and fMRI on human subjects with a strong emphasis on data analysis.

Application Deadline: 12.Dec.2023

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7. Fully Funded PhD Position in clonal biology

Summary of PhD Program:

A position for doctoral studies in clonal biology is available in the lab of Jonas Frisén at the Department of Cell and Molecular Biology, Karolinska Institutet. The lab is interested in the role of stem cells in cell turnover in healthy and pathological situations. We study the identity of stem cells and the organization of cellular lineages, the molecular regulation of cell production and the role of cell renewal in homeostasis and pathological situations. Many of our projects focus on stem cells in the brain and spinal cord with a focus on adult neurogenesis and the role of stem cells in regenerative processes.

Application Deadline: 11.Dec.2023

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8. Fully Funded PhD Position in translational epidemiology research

Summary of PhD Program:

This doctoral project brings together an international team of researchers from Karolinska Institutet and universities in Hong Kong. Our team uses large-scale population cohort to study the etiology of neurological disorders (JAMA, 2016; Alzheimer’s & Dementia, 2021; JAMA Psychiatry, 2023), and is interested in precision genome editing technologies (Nat. Biotech., 2015; Nature, 2016; PNAS, 2019; Nat. Comm. 2022), novel gene delivery and molecular tools (Nat. Biotech., 2019; PNAS, 2019; PNAS, 2021; Sci. Adv., 2023) and precision medicine (Nat. Med., 2014; JTO, 2022). Together, we take multidisciplinary approaches combining medical epidemiology and biotechnologies, and aim to identify and treat genetic alterations in selected neurological disorders.

Application Deadline: 08.Dec.2023

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9. Fully Funded PhD Position in Causes and consequences of endometriosis

Summary of PhD Program:

The doctoral student will contribute to the development of study designs, data processing, analyse large-scale national and regional registry data, as well as data from genome wide association studies (GWAS), and scientific writing. The student will use a variety of study designs and statistical methods, such as traditional cohort design, family-based designs and mendelian randomization (MR) study design. The student will actively participate in seminars at the department, present research results at international conferences, attend PhD courses and theoretical studies and training in epidemiology and statistical methods.

Application Deadline: 08.Dec.2023

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10.
Fully Funded PhD Position in tumor heterogeneity and drug resistance

Summary of PhD Program:

In this project we will use a technique called cell barcoding to identify efficient drug combinations to overcome tumor heterogeneity in pediatric cancer. In cell barcoding a molecular barcode is inserted into cells’ genomes which makes it possible to monitor thousands of tumor subclones simultaneously and see how they evolve as they respond to drugs. We use this to identify and characterize cell populations that survive standard of care treatment, and to identify drugs specifically targeting those cell populations – a concept we have termed Precision Lethality.

Application Deadline: 06.Dec.2023

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11. Fully Funded PhD Position in Exploring the role of the bone marrow microenvironment in low-risk myelodysplastic syndromes

Summary of PhD Program:

Myelodysplastic syndromes (MDS) comprise a broad spectrum of hematological malignancies affecting the hematopoietic stem cell compartment and causing myeloid cytopenias. The low-risk subset of disease in myelodysplastic syndromes has a higher survival rate than median but in general presents severe cytopenias with with limited treatment options. The studies in this project will functionally investigate bone marrow (BM) cell subsets and the global architecture of the low-risk MDS BM microenvironment to further the field’s understanding of MDS, and have the ultimate goal of uncovering novel critical regulatory mechanisms in MDS.

Application Deadline: 05.Dec.2023

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12. Fully Funded PhD Position in image acquisition and reconstruction for cardiovascular magnetic resonance imaging

Summary of PhD Program:

As a Ph.D. student, you will continue these advancements by exploring and implementing novel image acquisition and reconstruction methods that expand the capabilities of the sector-wise acquisition paradigm. Based in a highly translational research environment, the Ph.D. project specifically seeks to (1) enable motion-adaptive image acquisitions using multi-modal sensor input; (2) couple this to developments in image reconstruction and image analysis to form a framework for motion-adaptive imaging; and (3) investigate how motion-adaptive cardiac imaging expands our understanding of complex cardiac disease.

Application Deadline: 01.Dec.2023

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