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37 Postdoctoral Fellowships at Karolinska Institute, Solna, Sweden

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Are you holding PhD degree and looking for Postdoctoral Fellowships? Karolinska Institute, Solna, Sweden invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.

1. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

At the Teixeira lab (Ana Teixeira-group), we have developed DNA nanotechnology-based approaches to map and target membrane protein nanodomains (e.g. Ambrosetti et al, Nat Nanotechnology, 2021; Fang et al, ACS Nano, 2021; Verheyen, Fang et al, Nucleic Acids Research, 2020; Shaw, Lundin, et al, Nat Methods 2014). In this project, the postdoctoral research fellow will investigate the nanoscale spatial organization of insulin receptors in different tissues. This information will be used to develop multivalent insulin variants using DNA- and protein-based self-assembly.

Application Deadline: 30.Apr.2023

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2. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Senescent cells, which can release factors that cause inflammation and dysfunction, increase in adipose tissue and associate with obesity and hyperinsulinemia. The proposed project will determine whether oxidative stress and DNA damage in human adipocytes drives adipocyte senescence, and the associated pro-inflammatory secretory profile. A small molecule approach to attenuate adipocyte DNA damage and reverse adipocyte senescence will be investigated.

Application Deadline: 30.Apr.2023

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3. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

While it is acknowledged that the brain is an important regulator of blood glycemia, a crucial role for the peripheral nervous system in the control of homeostasis is emerging. The pancreas is densely innervated by the somatosensory nervous system, but the anatomical organization and function of these circuits are not fully understood. We hypothesize that these networks are key components of an unexplored, peripheral regulatory unit controlling glucose homeostasis. Our objective is to identify and interrogate the somatosensory networks innervating the pancreas, in mice, with an interdisciplinary strategy, drawing methods from the fields of neuroscience and physiology.

Application Deadline: 30.Apr.2023

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4. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Diabetes features a reduction in the number of functional β-cells, a key pathologic event that causes or exacerbates the dysregulation of blood glucose levels. Regenerating insulin-producing β-cells might prove a better treatment for diabetes, which is at present controlled but not reversed by insulin injections. Therefore, the main interest in the lab of Olov Andersson is to determine how small molecules and cellular mechanisms can promote regeneration of insulin-producing beta-cells and improve metabolic control, as potential curative approaches for diabetes. The successful applicant will use chemical-genetic screening techniques in zebrafish to identify compounds, genes and signalling pathways that can promote β-cell regeneration.

Application Deadline: 30.Apr.2023

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5. 04 Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The following 4 projects are available (click each project to reach the corresponding job posting):

  • Integrating transcriptomics and chemical biology for induction of Ăź-cells. Prinicipal Investigator: Olov Andersson
  • Somatosensory networks control glucose homeostasis. Principal Investigator: Alessandro Furlan
  • Investigating DNA damage as a driver of adipocyte senescence and inflammation in obese, hyperinsulinemic individuals. Principal Investigator: Kirsty Spalding
  • Mapping the biodistribution of multivalent insulin variants in zebrafish and in mice. Principal Investigator: Ana Teixeira

Application Deadline: 30.Apr.2023

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6. 03 Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We seek dedicated and creative postdoctoral researchers to join our team. You will be involved in studies exploring the burden, management and outcomes of major non-communicable diseases in ‘real world’ (routine practice). You will also explore conditions of use (adherence, compliance, off and on-label use) and the effect (effectiveness, safety) of a number of licensed drugs and devices. You will study unique data sources, including several Swedish Quality Registers and the Stockholm CREAtinine Measurements (SCREAM) project, a longitudinal administrative healthcare utilization cohort of >3 million residents of Stockholm with complete information on undertaken laboratory measurements.

Application Deadline: 25.Apr.2023

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7. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The successful candidate is expected to conduct epidemiologic research in cancer epidemiology, focused primarily on childhood cancer, but also other areas within cancer epidemiology. We have ongoing projects, but there is also room for own research ideas, where the richness of data available offer immense possibilities. The postdoc is also expected to supervise PhD students, and to participate as teacher in epidemiology both at the Master level and at the Doctoral program in Epidemiology. The position is for 2 years with the possibility of extension.

Application Deadline: 24.Apr.2023

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8. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The successful candidate will conduct the research with a special focus on deciphering molecular pathways mediating leukemic stem cell interaction with their niche under the supervision of the group leader (Dr. Hong Qian). In addition, the candidate is expected to participate in several collaborated project throughout her/his postdoc training. Further, the candidate is expected to participate in supervision of junior students in the group.

Application Deadline: 22.Apr.2023

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9. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are looking for a highly motivated and skilled scientist with experience in drug development and testing of compounds for anti-cancer potential. Advanced skills in in vitro and in vivo testing of drugs as well as basic skills in molecular and cell biology and biochemistry are important assets for this project. Other helpful skills are experience with fluorescence microscopy and flow cytometry. Candidates should be competent in spoken and written English. Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.

Application Deadline: 20.Apr.2023

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10. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our ambition is to discover innovative ways to stratify patients and to identify predictive and prognostic biomarkers by machine learning and AI. This postdoctoral position is focused on development and validation of methodologies for analysis and modelling of breast cancer histopathology image data together with clinical information. Machine learning and deep learning techniques are central in this computational pathology project aimed at improving phenotyping and patient stratification. The project is based on unique and large in-house datasets that include both image data together with clinical information and outcomes. The role would suit applicants who are interested in developing a career in AI/ML and data-driven cancer precision medicine.

Application Deadline: 20.Apr.2023

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11. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The postdoc will continue the successful line of investigations utilizing single-cell techniques to dissect human ILC and T cell biology in healthy and diseased tissues. The project involves handling of human lung tissues and isolation of innate and adaptive lymphocytes, single-cell RNA-sequencing (scRNAseq), high resolution/spectral flow cytometry and in vitro cell-differentiation and co-culture assays. As this is a team effort, excellent communication skills are essential, as is proven ability to work in multidisciplinary teams. It is expected that the postdoc also participate in other ongoing projects, supervises students and other researchers if necessary, as well as contribute to common lab duties.

Application Deadline: 17.Apr.2023

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12. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

As a postdoc in microbiome research, you will focus on analysis work concerning the role of the microbiome in several different projects all focusing on studying the microbiome and its interaction with the human host from a women’s health perspective. A central component of the role is to assume responsibility for bioinformatics analysis work in assigned studies, e.g. establish analysis plans combining microbiome data with additional metadata such as omics-data, questionnaires, etc. in order to perform the analysis work in collaboration with other colleagues at CTMR and external research partners with the ambition to generate new knowledge on the role of the microbiome for women’s health and scientific publications.

Application Deadline: 16.Apr.2023

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13. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are looking for a highly motivated postdoctoral researcher with broad experience in structural bioinformatics and biomolecular modelling. The candidate is expected to participate in collaborative efforts to develop a workflow for multiscale screening of human mutations, integrating different coarse-grained and atomistic simulation methods. The candidate will hold a shared position between Prof. Orellana “Protein Dynamics and Mutation” lab, focused on the development of biophysical modelling methods with a focus on disease mutations, and Prof. Grigelioniene translational research team, focused on the identification and validation of new genetic variants associated to rare skeletal diseases.

Application Deadline: 15.Apr.2023

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14. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral position on sensorimotor integration and neural control of movement is available at the Department of Neuroscience. The project will have a particular focus on the integration of sensory feedback on movements in mice. This is a collaborative project between the labs of Abdel El Manira, Francois Lallemend and Laurence Picton and will involve multiple advanced techniques. The selected candidate will investigate the functional properties and connectivity of proprioceptive neurons and will explore proprioceptive feedback pathways in the brainstem and spinal cord. The project will involve the use of viral tracing, electrophysiology, optogenetics and behavioral analysis.

Application Deadline: 13.Apr.2023

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15. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The research team of Assistant Professor Dr. Sylvain Peuget investigates how the bacterial microbiota participates in cancer initiation and progression. Metagenomics studies have highlighted dysregulation of the microbiota composition in cancer patients compared to healthy individuals. However, how bacteria influence cancer is still poorly understood. More specifically, we are interested in the molecular mechanisms which link bacterial dysbiosis, inflammation and alterations of the tumor suppressor p53 pathway, and ultimately cancer.

Application Deadline: 12.Apr.2023

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16. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

As a Postdoctoral Research fellow, you will be involved in the development of bioengineered extracellular vesicles (EVs) as novel cancer therapies and development of improved strategies for enrichment of tumor derived EVs as an improved liquid biopsy platform in cancer. Most of the research will initially be conducted utilizing cell lines and animal models before the methods are applied to patient material. The duties will involve developing stable cell lines for production of EVs engineered to harbor reporter proteins, with or without a therapeutic/targeting domain. The stable cells will be used both for screening of suitable cell source for therapeutic applications of EVs and for labeling of tumor derived EVs used for optimization of isolation techniques from complex media such as plasma.

Application Deadline: 10.Apr.2023

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17. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are looking for an experienced person with extensive bioinformatical knowledge in the field of systems genetics – integrating DNA and RNA sequencing with proteomics and clinical information from one or more datasets (e.g., GWAS). The applicant should have substantial proficiency working in a Linux environment, as well as possess expertise in the coding languages of Python and R. Experience of working with a computing server is required. To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

Application Deadline: 07.Apr.2023

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18. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Over the course of the postdoctoral appointment, the development of various behavioral, molecular, and morphological analyses to evaluate the role of receptor-driven signaling and brain circuitries on the effects of fast-acting antidepressants (ketamine) and pro-resilience pharmacological strategies will be one important focus of the project. Successful applicants will generate data that guide the development of novel pharmacological approaches (rapid-onset and pro-resilience strategies) to be tested in animal models of stress and depressive-like behavior. Independence and strong motivation are expected throughout the project.

Application Deadline: 06.Apr.2023

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19. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our research aims to elucidate how viral products mimic or hijack key cellular functions in order to promote virus persistence and spread, and to understand how these viral strategies may lead to malignant transformation. We particularly focus on signaling pathways that are regulated by post-translational modification by ubiquitin, SUMO and NEDD8. The ultimate goal of our research is to identify new regulatory interactions that may be targeted to control virus infection and its potentially life-threatening consequences.

Application Deadline: 06.Apr.2023

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20. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We search for a postdoctoral researcher that together with Professor Birgitta Henriques Normark, her research group and her collaborators will work on projects in bacteriology and respiratory tract infections. The World Health Organization (WHO) classifies infectious diseases as one of the greatest global health threats. Lower respiratory tract infections are a major cause of death globally. Pneumococci are a major contributor to both morbidity and mortality and being the most common causes of milder respiratory tract infections such as otitis media and sinusitis as well as of severe diseases such as pneumonia, septicemia and meningitis. However, pneumococci are also common colonizers of the upper respiratory tract of healthy children.

Application Deadline: 05.Apr.2023

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21. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are looking for a postdoc who will work with cancer genomics data from randomized clinical trials. The Cancer Genomics team at MEB, which is part of Henrik Grönberg’s research environment, performs prospective genome profiling for several clinical trials including ALASCCA and ProBio. The team for cancer genomics is led by senior researcher Johan Lindberg and consists of a postdoctoral fellow, four bioinformaticians, two software developers and two laboratory engineers.

Application Deadline: 2023-04-05

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22. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We seek a highly motivated postdoctoral fellow to join the team of MD PhD Hanna Brauner in focusing on finding novel pathogenic mechanisms and biomarkers for patients with autoimmunity and lymphoma. We have access to unique clinical material, which we will assess in a truly translational approach, applying cutting edge methods to understand key clinical questions. The team of Hanna Brauner has a net-work of national and international collaborators among both basic science researcher and clinical researchers and is associated to the research group of professor Marie Wahren Herlenius.

Application Deadline: 05.Apr.2023

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23. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are looking for a highly motivated postdoctoral fellow who can work independently and develop his/her own ideas and visions and with a strong drive for a future career in research. The successful applicant must have a Ph.D. from an appropriate discipline such as toxicology, cell- or molecular biology with in-depth understanding of cellular signaling and carcinogenesis. A documented background in standard cell biology techniques is required. Documented hands-on experience of data analysis of next-generation sequencing data is required. Advanced understanding and experience of data analysis of whole genome sequencing data is particularly meritorious.

Application Deadline: 04.Apr.2023

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24. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are looking for a highly motivated postdoc with strong bioinformatics background to join our multidisciplinary team consisting of clinicians, bioinformaticians, computer scientists, and biologists. The postdoc candidate’s main tasks will be establishing pipelines for analyzing gene expression data from bulk-/single-cell RNA-sequencing, spatial transcriptomics, and other platforms (e.g., microarray or digital multiplexed gene expression platforms). DNA sequencing (WES or targeted sequencing of gene panels) and chromatin accessibility sequencing (ATAC-seq) will also be carried out. The postdoc candidate will participate in the somatic mutation and copy number alteration analysis concerning the interplay between tumor heterogeneity and treatment resistance mechanisms.

Application Deadline: 03.Apr.2023

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25. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The project is part of a Horizon 2020 supported exercise intervention RCT for patients with metastatic breast cancer – PREFERABLE. Specifically, the focus of the project will be on linking exercise induced changes in immune function to disease progression and therapeutic response. To accomplish this, the applicant will have access to RCT data, state of the art human exercise facilities, animal models, and pre-clinical labs in an innovative and translational environment.

Application Deadline: 03.Apr.2023

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26. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are seeking a highly motivated and ambitious individual from universities around the world to join the research team of Assistant Professor Dr. Jette Lengefeld as a Postdoctoral Researcher to mechanistically understand novel mechanisms of human stem cells that drive aging and disease. The Lengefeld research group uses hematopoietic stem cells from mice and human bone marrow donations to discover how deregulation of cellular size is connected to aging and cancer.

Application Deadline: 02.Apr.2023

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27. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The successful candidate should show a high level of responsibility and independency, be able to collaborate with others in a team, and possess good English communication skills. Applicants should have a strong neuroscience background with documented experience in electrophysiology. Experience in surgery, animal behavior, computer programming, and manuscript writing, are highly advantageous. The project will involve in vivo patch-clamp recordings, optogenetics, and imaging in the mouse basal ganglia.

Application Deadline: 01.Apr.2023

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28. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

During the development of obesity and insulin resistance, ectopic lipid accumulation occurs in various organs. In the liver, such condition is called non-alcoholic fatty liver disease (NAFLD), which can progress to more severe stages, such as non-alcoholic steatohepatitis (NASH), cirrhosis, and/or hepatocellular carcinoma. Liver fibrosis is the most important predictor of prognosis in NAFLD patients. In this project, we will focus on NAFLD and develop an innovative non-invasive machine learning model to monitor the real-time disease progression and future risks of NAFLD patients.

Application Deadline: 31.Mar.2023

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29. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The postdoctoral candidate will work with questions centered on tissue imprints on T cell functions and the establishment of new mRNA delivery platforms to create CAR-T cells. The candidate will work in close collaboration with different members of the group to apply gene-editing technologies (e.g. CRISPR-Cas9) to mechanistically dissect different functions of human memory T cells in peripheral blood and tissues. As such, we are seeking a postdoctoral candidate with a PhD, who will work as an integrated member of our team, being involved in several ongoing projects and driving their project forward.

Application Deadline: 31.Mar.2023

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30. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Larsson lab focuses on understanding the role of mRNA translation in several cancer types; and in both cancer and stromal cells. The focus is on achieving transcriptome-wide and detailed molecular understanding of how mRNA translation is dysregulated in cancer. The lab has expertise in development of state-of-the-art methods for wet-lab based studies of mRNA translation as well as development of computational tools to analyse the generated data. The focus for the project will be to use biostatistics and bioinformatics to understand how mRNA translation is organized and orchestrated in health and disease.

Application Deadline: 31.Mar.2023

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31. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The postdoc will focus on to understand how B cells interact with innate immune cells during the initial steps of activation and how this can lead to break of tolerance. We have recently generated novel mouse strains that are yet to be published and the postdoc will use these to study B cell activation. This includes conditional targeting of innate immune recognition pathways in macrophages and neutrophils as well as lineage tracing of regulatory B cells. Besides in vivo models the lab has experience in working with in vitro models for B cell activation and regulation as well as using patient material to verify findings.

Application Deadline: 31.Mar.2023

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32. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The postdoctoral researcher will be involved in our ongoing efforts to improve the understanding of neutrophil function and interaction with mesenchymal stem cells. We are also working on neutrophil functional assays to characterize the neutrophil transfusion products. This work requires a creative approach to incorporate the functional assays and molecular work to dissect the research questions.

Application Deadline: 30.Mar.2023

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33. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are looking for a highly motivated, knowledgeable and experienced postdoctoral researcher to combine science in both basic animal research and human clinical neuroscience. You will be responsible for analyzing brain data acquired with methods such as magnetic resonance imaging (MRI), magnetoencephalography (MEG), epigenome-wide DNA methylation, calcium imaging and immunofluorescence imaging.

Application Deadline: 30.Mar.2023

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