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35 Postdoctoral Fellowships at City of Hope, California, USA

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Are you holding PhD degree and looking for Postdoctoral Fellowships? City of Hope, California, USA invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.

1. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow position is available in Dr. Rupangi Vasavada’s lab in the Department of Translational Research and Cellular Therapeutics in the Arthur Riggs-Diabetes and Metabolism Research Institute at City of Hope. The lab is interested in understanding the pathophysiology of diabetes, assessing the role of extracellular vesicles in Type 1 and Type 2 diabetes as well as in aging. We are targeting specific biological pathways to enhance beta cell health, testing their effects from bench to bedside, to find therapeutics to combat the disease. The lab employs a combination of cellular and molecular techniques, mouse models and patient samples to assess these areas.

Application Deadline: Open Until Filled

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2. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. Behnam Badie at the Beckman Research Institute of City of Hope, a prestigious NCI-designated Comprehensive Cancer Center. The research interests of Behnam Badie, M.D., focus on brain tumor immunology. More specifically, his research team is attempting to develop novel immunotherapy approaches for malignant brain tumors through the activation of microglia and macrophages using nanoparticles. This research is currently funded by the National Cancer Institute and other organizations.

Application Deadline: Open Until Filled

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3. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. David Chen’s research group at the Beckman Research Institute of City of Hope is seeking a highly skilled and motivated Postdoctoral Fellow to join their dynamic team. Dr. Chen is a distinguished leader serving as the Director of the Division of Epigenetics and Transcriptional Engineering at City of Hope Cancer Center. The primary focus of his lab revolves around investigating epigenetic mechanisms, drug resistance, and identifying therapeutic targets in various cancers through cutting-edge techniques such as high throughput genetic screens. The lab is proficient in high-throughput CRISPR genetic screens for identifying novel therapeutic targets for cancer treatment.

Application Deadline: Open Until Filled

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4. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow to study the molecular mechanisms involved in the increased risk of cancer in patients with diabetes. The Shuck lab specializes in detailed studies of the cellular impact of reactive molecules produced during metabolic dysfunction. Specifically, we are interested in investigating the induction of covalent adducts on DNA, RNA, and protein using human prostate cancer cell lines. The position will encompass a variety of techniques including sterile cell culture, characterization of cellular changes induced by hyperglycemia, use of biochemical assays, and analytical techniques such as HPLC and mass spectrometry. The trainee will benefit from a close interaction with world-class clinical and basic science faculty and staff, and gain experience in state-of-the-art genomics and analytical techniques.

Application Deadline: Open Until Filled

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5. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr Ed Boas, at the Beckman Research Institute of City of Hope, a prestigious NCI-designated Comprehensive Cancer Center. We are looking for a biomedical engineer, materials scientist, immunologist, or cancer biologist who can help us develop new minimally invasive cancer therapies, such as new materials or devices for drug delivery into tumors (percutaneous or intra-arterial). We are one of the few interventional oncology groups in the United States with a basic science lab, large animal tumor model, and several active clinical trials, which enables us to translate new discoveries from bench to animal to bedside.

Application Deadline: Open Until Filled

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6. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Shi laboratory has been well known for stem cell research, including stem cell-based disease modeling and cell therapy development. This laboratory is one of the pioneers in establishing disease models and cell therapies using the human induced pluripotent stem cell (iPSC) platform and has published extensively in this area. Some of the papers published by the Shi laboratories include Shi et al. Nature Reviews Drug Discovery 16: 115-130, 2017; Li et al. Cell Stem Cell 23: 239-251, 2018; Feng et al. Advanced Science 7: 2002155, 2020; Wang, et al. Cell Stem Cell 28: 331-342.e5, 2021; Chen et al. Advanced Science: 8: e2101462, 2021; Cui et al. Nature Cancer 2: 932-949, 2021.

Application Deadline: Open Until Filled

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7. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. ZJ Sun at Beckman Research Institute of City of Hope, one of a prestigious group of NCI-designated Comprehensive Cancer Centers. The candidate will directly work on the novel and ongoing projects on prostatic stem cells and stem cell niches in prostate development and tumorigenesis using “cutting edge” and unbiased analytic tools and unique and innovative genetically engineered mouse models (please see some of the recent publications: PLoS Genet 2020 Jan 13:16(1):e1008588; Development 2021 Jan 11:148(1):dev196048; Development 2021 Oct 1:148(19):dev199738; Nat Commun 2022 Jul 28:13:4364; Nat Commun 2022 Nov 2:13:6552).

Application Deadline: Open Until Filled

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8. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. Yuman Fong, at the Beckman Research Institute of City of Hope, a prestigious NCI-designated Comprehensive Cancer Center. The candidate will directly work on oncolytic virus project, which involves assessing safety and anti-tumor efficacy of different viral constructs, in vitro and in mice. Oncolytic virotherapy is a major focus of our laboratory. The candidate will be working with our oncolytic poxvirus (CF33) and potentially other viral platforms.

Application Deadline: Open Until Filled

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9. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. Alberto Pugliese, MD in the AR-DMRI Department of Diabetes Immunology. The research is highly translational and primarily focused on human type 1 diabetes. The candidate will participate in several projects. Major ongoing projects are investigating miRNA biomarkers, pancreas pathology, and novel therapeutics, also in the context of the analysis of live pancreas tissue from organ donors obtained from the Network for Organ Donors with Diabetes (nPOD), of which Dr. Pugliese is Executive Co-Director, and in future clinical trials. Upcoming studies are projected to include the analysis of samples from patients with type 1 diabetes participating in clinical trials, with trials expected to start in late 2023 and 2024. Additional studies involve analysis of samples from recipients of pancreas-kidney transplant in the context of recurrent type 1 diabetes.

Application Deadline: Open Until Filled

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10. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The laboratory of Binghui Shen, Ph.D. at The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. The Shen laboratory has been focusing on DNA replication/repair pathway components, cancer genetics and epigenetics, and cancer etiological and therapeutics modeling. The laboratory is seeking additional members to work on several new projects. Recent Ph.D. graduates or equivalents in the field of biological/medical sciences with ambition for a scientific career and interest in DNA replication and repair, genome stability, and cancer biology and skills in molecular biology, genetics or biochemistry are encouraged to apply. Bioinformatics and data mining skills are a plus for considerations.

Application Deadline: Open Until Filled

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11. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our research is focused on translational research as it relates to genomic and epigenomic characterization of various gastrointestinal cancers (GI) including colorectal, pancreatic and gastric cancers, and some of the key research topics include: 1) Development of circulating DNA/RNA-based liquid biopsy biomarkers for cancer diagnosis, prognosis and predictive response to various therapies. 2) Study the epigenetic basis of GI cancers (e.g. aberrant DNA methylation, histone modifications and non-coding RNAs. 3) The genetic basis of early-onset and familial/hereditary colorectal cancers. 4) The role of tumor microenvironment, stem cells, immune regulation and identification of novel targeted therapies. 5) The role of extracellular vesicles/exosomes as in cancer pathogenesis and their role as disease biomarkers.

Application Deadline: Open Until Filled

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12. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Join our successful and productive research team at the Beckman Research Institute at City of Hope where we are studying the biological mechanisms of breast cancer susceptibility in the context of aging. This current position is focused on using cell and molecular techniques to examine emergent mechanical properties of epithelial cells that are highly susceptible to breast cancer initiation. This mechanobiology work is the product of a long-term, NIH funded, collaboration with a bioengineering group at UC Berkeley. We are using, and evolving, a mechano-node pore sensing (mechano-NPS) platform to explore unique mechanical properties of cells that are associated with chronological or biological age, lineage, and cancer progression stage.

Application Deadline: Open Until Filled

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13. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow position is available in the laboratory of Edwin R. Manuel, PhD, at City of Hope, Beckman Research Center, Monrovia, CA. Our lab is interested in utilizing tumor-colonizing, bacterial-based agents as novel immunotherapy for solid and hematologic malignancies. We are recruiting enthusiastic, motivated scientists who are seeking a fast-paced academic research environment. Our lab in the Department of Immuno-Oncology focuses on engineering tumor-colonizing bacteria to target components of the tumor microenvironment that contribute poor drug delivery, immune suppression and cancer metabolism.

Application Deadline: Open Until Filled

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14. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow for translational research in the field of cancer biology and therapy. Ongoing studies are focusing on targeting ovarian cancer tumor microenvironment by conditionally replicative oncolytic virus and development of new agents targeting extrinsic and intrinsic apoptotic pathways.

Application Deadline: Open Until Filled

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15. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow position is available in the laboratory of Dr. Heather McGee, MD, PhD, Assistant Professor in the Departments of Radiation Oncology and Immuno-Oncology in the Beckman Research Institute at City of Hope. Dr. McGee is looking for a post-doctoral fellow who is very motivated to lead exciting scientific projects and test novel hypotheses. The post-doctoral researcher must have a background in tumor immunology, murine tumor models and multicolor flow cytometry. The goals of the McGee lab are to understand how radiation activates tissue resident immune cells in various tumor microenvironments. The long-term goals of the McGee lab are to identify key molecular and immunologic pathways activated by radiation that can be targeted to enhance anti-tumor immunity and/or minimize normal tissue toxicity for gastrointestinal malignancies.

Application Deadline: Open Until Filled

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16. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are recruiting enthusiastic, motivated scientists who are seeking a fast-paced, team-based academic research environment. Our lab in the Department of Immuno-oncology focuses on how blood and immune cells develop, function, and interact with other cells, with a second focus on how blood stem cells become malignant. We use mass spectrometry to identify activated protein circuits in rare blood stem and progenitor cell populations, including therapeutic chimeric antigen receptor (CAR) T cells, and combine that knowledge with fundamental immunological principles to improve and devise new therapies for pediatric cancers and blood disorders.

Application Deadline: Open Until Filled

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17. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. The Williams Research Team seeks a self-motivated, results-driven postdoc to drive the development of the generation of therapeutic monoclonal antibodies. Expertise required include thorough knowledge of protein engineering (cloning, expression, purification), crystallography (crystallization, optimization, data collection and structure determination), biochemistry (enzyme kinetics) and biophysics (Surface Plasmon Resonance, Iosthermal Ttitration Calorimetry, etc).

Application Deadline: Open Until Filled

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18. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are seeking a talented and motivated Postdoctoral Fellow to work in the laboratory of Dr. Srividya Swaminathan in the Department of Systems Biology, City of Hope. We study processes within lymphocytes and those outside (in the immune microenvironment) that drive the development of lymphoid malignancies including B- and T- cell acute lymphoblastic leukemia (ALL) and lymphomas. We apply this to develop therapies that specifically target malignant lymphocytes. Research in our lab spans Hematology, Oncology, and Immuno-Oncology. The Postdoctoral Fellow who joins the team will lead a project focused on specifically targeting diseased immune subsets in systemic lupus erythematosus (SLE) and indolent lymphomas.

Application Deadline: Open Until Filled

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19. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Danilov’s group coordinates a number of Phase I/II clinical trials, thus presenting an opportunity to verify the pre-clinical hypotheses in the clinical setting and conferring immediate relevance to pre-clinical investigations. This position is created to continue research studies currently funded by the NCI R01, the Leukemia and Lymphoma Society Translational Research Program Award, MCL Research Initiative and Scholar Award. The project will match the candidate’s interests and experience.

Application Deadline: Open Until Filled

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20. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Caligiuri/Yu Laboratory at Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. We are a fast-paced lab involved in cutting-edge technology, research and clinical immunotherapy investigations. We are currently looking for a postdoctoral fellow who will develop chimeric antigen receptor T- and NK-cell therapies in combination with oncolytic viruses for the treatment of solid tumors, especially glioblastoma. The PhD candidate should have experience in the fields of immunology and cancer biology with a strong track record. This position will interact and collaborate with a team of researchers with similar interests in developing cell-based therapies in a translational research environment.

Application Deadline: Open Until Filled

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21. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Mingye Feng’s laboratory at the Beckman Research Institute of City of Hope is looking for a talented and highly motivated Postdoctoral Fellow. Dr. Feng is an awardee of the V Scholar Award from the V Foundation for Cancer Research, the Damon Runyon – Dale F. Frey Award for Breakthrough Scientists from the Damon Runyon Cancer Research Foundation, the K99/R00 Pathway to Independence Award from NIH, and NIH R01 grants. His laboratory employs cutting-edge techniques to understand mechanisms of macrophages in cancer immunosurveillance, identify immune checkpoints and ligands on various hematopoietic malignant and solider tumor cells with high-throughput screening and protein engineering approaches developed in the lab, and develop novel cancer immunotherapies targeting metastatic cancer cells.

Application Deadline: Open Until Filled

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22. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our research is focused on translational research as it relates to genomic and epigenomic characterization of various gastrointestinal cancers (GI) including colorectal, pancreatic and gastric cancers, and some of the key research topics include: 1) Development of circulating DNA/RNA-based liquid biopsy biomarkers for cancer diagnosis, prognosis and predictive response to various therapies. 2) Study the epigenetic basis of GI cancers (e.g. aberrant DNA methylation, histone modifications and non-coding RNAs. 3) The genetic basis of early-onset and familial/hereditary colorectal cancers. 4) The role of tumor microenvironment, stem cells, immune regulation and identification of novel targeted therapies. 5) The role of extracellular vesicles/exosomes as in cancer pathogenesis and their role as disease biomarkers.

Application Deadline: Open Until Filled

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23. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow Position is available in the laboratory of Dr. Tijana Jovanovic-Talisman. Biological nanoparticles that are continuously shed by cells – namely extracellular vesicles (EVs) – are an emerging and exciting strategy for performing minimally invasive diagnoses. Because EVs are loaded with disease-specific molecules, they represent an excellent source of biomarkers. The project involves employing cell biology and super-resolution microscopy approaches to characterize extracellular vesicles that contain disease-specific or tissue-specific molecules. Ultimately, the goal is to develop a new platform to perform molecular level diagnoses for precision medicine.

Application Deadline: Open Until Filled

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24. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are looking for a talented and highly motivated Postdoctoral Fellow, to join the Laboratory for Cellular Medicine (LCM), Center for Gene Therapy at the Beckman Research Institute of City of Hope. The candidate will join a well-established group performing cutting-edge research, development and qualification of large-scale processes, and manufacture of products for gene therapy clinical trials, including first-in-human studies with genetically engineered (ge) hematopoietic stem and progenitor cells (HSPC) and T cells.

Application Deadline: Open Until Filled

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25. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Nadia Carlesso’s research is focused on the mechanisms of leukemogenesis and identification of novel therapeutic approaches in poor prognosis T-ALL. Following recent laboratory discoveries, her group is exploring novel approaches to target the microenvironment/oncogene cooperation driving chemoresistance and relapse in T-ALL leukemia stem cells. This project is nested on a larger program directed by Dr. Carlesso that focuses on the relationships between the tumor microenvironment, inflammation, and stem cell biology in hematopoietic diseases. Nadia Carlesso, M.D., Ph.D. | City of Hope

Application Deadline: Open Until Filled

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26. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Ngo laboratory at the Department of Systems Biology, City of Hope is seeking a highly motivated Postdoctoral Fellow to lead a federally funded project in lymphoma and immunotherapy. Our laboratory studies molecular mechanisms and identifies therapeutic targets in hematologic malignancies. Candidates having interests in cancer biology and immunology with hands-on experience in working with hematopoietic cells and handling animals are encouraged to apply. Candidates with at least one first-author paper will be given more priority.

Application Deadline: Open Until Filled

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27. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Williams lab is looking for a highly motivated postdoctoral student interested in working in translational medicine to treat cancer. The overarching goals of the group are to identify and address unmet clinical needs (e.g., on-target, off-tissue toxicities) by rapidly translating novel molecular designs to the clinic. Using an atoms-up approach, our group pioneered the concept and development of tumor-activated IO monoclonal antibodies, leading the formation of Xilio Therapeutics which has two products currently in phase 1/2 clinical trials. We also discovered and subsequently developed a unique peptide-Fab interaction that allows us to rapidly functionalize monoclonal antibodies including antibody-drug conjugates, bispecifics including NK and T cell engagers, antibody-based imaging reagents, and switchable CAR T cells.

Application Deadline: Open Until Filled

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28. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for a highly motivated individual in the laboratory of Dr. Larry Kwak, at the Beckman Research Institute of City of Hope, a prestigious NCI-designated Comprehensive Cancer Center.

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29. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Postdoctoral Fellow will work on projects with a focus on improving accessibility of cancer genomics information and integrating technology to improve health literacy. The Postdoctoral Fellow will participate in ongoing research, with a particular focus on cancer genomics, information technology innovations to improve care, cancer care delivery, data management and analysis, project coordination and management, and writing and preparation of manuscripts and grant applications. Considerable opportunities for mentored professional development including analytic skills for quantitative and qualitative data, writing lead-author papers, and designing, applying for, and conducting grant-funded research.

Application Deadline: Open Until Filled

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30. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our group is interested in discovering novel genetic and epigenetic regulations and deciphering their underlying molecular mechanisms in normal developmental processes (e.g., hematopoiesis) and tumorigenesis (e.g., leukemogenesis). We cover research areas with relevance to Hematology, Immunology, and Cancer Biology, with an emphasis on RNA epigenetics (mainly focusing on the N6 methyladenosine (m6A) modification) and DNA epigenetics (mainly focusing on the TET1/2/3-mediated DNA demethylation) associated basic and translational research. Our research involves experiments with primary human cancer cells, cancer and stem cell transplantation models, mouse genetics, classic molecular, biochemistry and cell biology, functional genomics, signal transduction, and large-scale data analysis and computational biology.

Application Deadline: Open Until Filled

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31. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. Ya-Huei Kuo, at the Beckman Research Institute of City of Hope, a prestigious NCI-designated Comprehensive Cancer Center. The candidate will directly work on identifying mechanisms contributing to leukemia pathogenesis, immune evasion and therapy resistance; developing novel leukemia therapeutics; and participate in a multidisciplinary team work to study information flow and state-transition at multi-dimensional scales.

Application Deadline: Open Until Filled

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32. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are currently seeking highly motivated and talented individuals to fill four postdoctoral positions in the laboratory of Dr. Javier Gordon Ogembo at City of Hope’s Department of Immuno-Oncology. The positions are available in the following areas (check requirements for each area at the bottom):
1. Gamma-herpesvirus vaccine development
2. Gamma-herpesvirus T cell immunology and therapeutics
3. Gamma-herpesvirus protein and antibody structural studies
4. Use of preclinical animal models to assess gamma-herpesvirus entry mechanism and vaccine development.

Application Deadline: Open Until Filled

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33. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Postdoctoral Research Fellow will explore signaling pathways relevant to drug development and discovery of basic mechanisms of cancer biology and novel therapeutic targets and epigenetic and genetic prognostic biomarkers in cancers. The fellow will be assigned projects and be responsible for designing and performing in vitro and in vivo experiments, collecting and analyzing data, writing grants, publications, and disseminating findings.

Application Deadline: Open Until Filled

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34. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow position is open in the laboratory of Yingfeng Deng in the Department of Diabetes and Cancer Metabolism at the City of Hope Beckman Research Institute. The Deng laboratory studies the homeostasis of uridine and its role in metabolism, which provides a new angle for understanding the pathophysiology of obesity, diabetes, and cancer. Work in the lab utilizes both genetically engineered mouse models and in vitro systems. A combination of state-of-the-art surgical, genetic, cellular, biochemical, imaging, and metabolic flux approaches is currently used in the lab.

Application Deadline: Open Until Filled

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35. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The candidate is expected to be an innovative scientist with knowledge and experience in molecular oncology (integrative multiomic data analysis), precision pathology (advanced Assisted image analysis on immunofluorescence-stained slides), Immunohistochemical assays and genomic profiling. Interests and knowledge in the analysis of data generated through next generation sequencing and other global technologies including transcriptomic and mutational analysis as well as correlative analysis of different datasets would be desirable. Our group works very collaboratively in a supportive and stimulatory environment with the goal of understanding the pathogenesis of DNA damage response, discovering novel therapeutic targets, and improving the treatment and outcome of women’s cancer patients.

Application Deadline: Open Until Filled

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