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30 Postdoctoral Fellowships at St. Jude Children’s Research Hospital, Tennessee

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Are you holding PhD degree and looking for Postdoctoral Fellowships? St. Jude Children’s Research Hospital, Tennessee invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.

1. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral fellow position is available in the Torres lab to study the role of toxins in Staphylococcus aureus pathogenesis. A PhD or equivalent in microbial genetics, protein biochemistry, microbial pathogenesis, structural biology, or immunology is required. Applicants should have a strong publication record, exceptional communication and organizational skills, willingness to work in a team atmosphere, and should have excellent multitasking abilities.

Application Deadline: Open Until Filled

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2. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Gottschalk Laboratory is seeking a highly motivated and creative candidate for a fully supported postdoctoral fellowship to develop immune-based therapies. The postdoctoral fellow will join a highly collaborative research group that strives to build and maintain a culture of respect, diversity, and inclusion. Likewise, the Gottschalk Laboratory cares deeply about the success and professional growth of its lab members. The research project is aimed to develop T-cell-based therapies for pediatric solid tumors. Studies are focused on using genetic engineering approaches to not only render immune cells cancer specific, but also improve their effector function.

Application Deadline: Open Until Filled

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3. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Blanchard laboratory in the Department of Structural Biology is seeking a highly motivated Postdoctoral Fellow with experience in protein and membrane protein biochemistry to join a newly funded GPCR collaborative project to investigate the structural dynamics of GPCRs and their signaling partners using biophysical methods, including single-molecule FRET (smFRET).

Application Deadline: Open Until Filled

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4. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A fully funded postdoctoral position is available in the Clements group in the Department of Hematology at St. Jude Children’s Research Hospital to study how the adult hematopoietic system is established during vertebrate embryonic development. We are interested in understanding how early precursors of the sympathetic nervous system and vascular smooth muscle precursors interact with developing endothelial cells to establish the earliest hematopoietic stem cells. Our recent findings (Nature Cell Biology, 19:457-467, 2017) and unpublished data define the existence of this connection in in vertebrates and we are now working to better understand key details.

Application Deadline: Open Until Filled

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5. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

St. Jude is seeking outstanding candidates for postdoctoral fellowship positions in pediatric cancer survivorship research. As a fellow, you will benefit from access to unique datasets and expertise; a top-ranked scientific environment; and superb benefits, mentoring, and professional development. Positions are available in diverse research areas, including epidemiology, genetics, computational biology, psychology and neuropsychology, neuroscience, exercise physiology, oncology, pharmacology, radiology, surgery and biostatistics. St. Jude leads two of the world’s largest pediatric survivorship research studies, St. Jude LIFE and the Childhood Cancer Survivor Study (CCSS).

Application Deadline: Open Until Filled

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6. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Postdoctoral preceptors associated with the program are drawn from the departments of Infectious Diseases, Structural Biology, Chemical Biology & Therapeutics, Immunology and Pharmaceutical Sciences, bringing complementary expertise to this enterprise that not only seeks to understand the biology of infection but also strives to develop therapies to combat them. This expertise includes structural biology, virology and bacteriology, microbial genomics, drug discovery, high-throughput screening, medicinal chemistry, immune responses to infection and therapies, and vaccine platforms and adjuvants. All trainees will be instructed in grant writing, rigor and reproducibility, ethics and mentoring.

Application Deadline: Open Until Filled

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7. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

St. Jude is seeking outstanding candidates for postdoctoral fellowship positions in the Childhood Hematological Malignancies Training Program. This prestigious, NIH-sponsored T32 training program leverages the exceptional research infrastructure at St. Jude to train top-tier postdoctoral fellows with the necessary skills to lead independent research programs. Hematological malignancies are the most common childhood tumors, and despite remarkable advances in survival rates, they remain a leading cause of cancer death. The last decade has witnessed significant progress in understanding the genetic basis of these tumors, which now requires systematic efforts to translate the wealth of genomic discoveries into new experimental models and therapeutic advances.

Application Deadline: Open Until Filled

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8. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are seeking a highly motivated and creative candidate for a fully supported postdoctoral fellowship to develop immune-based therapies. Specifically, the research is aimed to develop cell-based immunotherapies for pediatric tumors. Studies are focused on using genetic engineering approaches to not only render immune cells cancer specific, but also improve their effector function. Genetically modified immune cells will be studied in preclinical models with special emphasis on how adoptively transferred cells interact with tumor cells, the tumor microenvironment, and resident immune cells.

Application Deadline: Open Until Filled

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9. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The candidate will join a team focused on investigating the dynamics of intratumoral heterogeneity in rhabdomyosarcoma, a pediatric solid tumor. We have multiple projects focused on a variety of scientific questions in pediatric rhabdomyosarcoma, including efforts to map the molecular drivers of self-renewal in persistent progenitor cells, the role of lineage plasticity in fusion-positive rhabdomyosarcoma, and the testing of targeted combination therapy to prevent rhabdomyosarcoma recurrence. The Patel lab is a multidisciplinary team, and we use a combination of single-cell sequencing, patient-derived models of cancer, and computational biology to model tumor biology.

Application Deadline: Open Until Filled

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10. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The laboratory of Dr. Peijun Ma in the Department of Pharmacy and Pharmaceutical Sciences in St. Jude Children’s Research Hospital, Memphis, TN is a new research group that uses single-cell genomics and transcriptomics to study antibiotic resistance and persistence in bacterial pathogens. Past work has focused on developing bacterial single-cell RNA sequencing technology (Ma et al., Cell, 2023;) and understanding the evolution of antibiotic resistance in gram-negative bacterial pathogens (Ma et al., eLife, 2021;).

Application Deadline: Open Until Filled

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11. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Abraham lab studies gene expression-regulation mechanisms in healthy and diseased mammalian cells. We are recruiting computational biologists to collaboratively develop computational tools and frameworks to analyze high-throughput sequencing (-omics) data. We build analytical software pipelines to find answers to biological questions about gene regulation in big datasets, usually from applied sequencing experiments like ChIP-Seq, RNA-Seq, and Hi-ChIP. Our interests center on enhancers and super-enhancers. Specifically, we seek to understand how these regulatory elements establish gene expression programs in healthy cells, and how enhancers are altered by mutation, abused by mistargeting, and targetable with drugs in diseased cells.

Application Deadline: Open Until Filled

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12. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral researcher position is available in Dr. Yong Feng’s laboratory at the Department of Immunology in St. Jude Children’s Research Hospital (www.stjude.org/feng). Research in Dr. Feng’s laboratory is utilizing innovative approaches and cutting-edge technologies to decipher the mechanisms governing T cell tolerance involved in autoimmunity and anti-tumor immune response. Highly self-motivated candidates with recently granted Ph.D. or equivalent in immunology, genetics, molecular biology, cell or developmental biology are invited to apply. Candidate will be supported by an NIH grant to explore an emerging area in T cell biology.

Application Deadline: Open Until Filled

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13. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Mittag laboratory invites applications for a Postdoctoral Research Fellow to work on structures of the tumor suppressor and ubiquitin ligase component SPOP. We have recently solved the first cryo-EM structures of full-length SPOP (Cuneo et al. Mol Cell 2023), and they have revealed interfaces that had not recently been observed in structures of smaller constructs. Importantly, these interfaces are lined with cancer mutations whose molecular mechanisms were not previously understood, but now provide molecular explanations for pathophysiological mechanisms. We have also revealed that certain mutations lead to large changes in quaternary assembly.

Application Deadline: Open Until Filled

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14. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Several postdoctoral positions are available in the laboratory of Dr. Victor J. Torres in the new Department of Host-Microbe Interactions at St. Jude Children’s Research Hospital. The Torres lab is interested in dissecting the complex interactions between pathogenic bacteria and the mammalian host. Currently, the lab is focusing on antibiotic resistant (AMR) bacteria, which have been recognized by the World Health Organization as a serious threat to human health. We take advantage of multidisciplinary approaches and combine techniques from bacteriology, genetics, molecular biology, biochemistry, structural biology, cellular biology, and immunology with primary tissue culture models and a variety of murine models of infection, to address our favorite questions.

Application Deadline: Open Until Filled

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15. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Ma Lab in the department of Computational Biology is seeking outstanding candidates for a postdoctoral research associate focused on developing novel computational approaches to understand the molecular mechanisms underlying cancer initiation and clonal evolution and to detect such events early, which is expected to significantly impact clinical management of childhood cancers. Dr. Xiaotu Ma has extensive experience in cancer genomics, intra-tumor heterogeneity and computational method development.

Application Deadline: Open Until Filled

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16. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

St. Jude Children’s Research Hospital is committed to the education and training of the next generation of research scientists. St. Jude trainees are able to learn from clinical and basic science investigators who work in close proximity and interact regularly to translate scientific discoveries into improved therapies for children. If you are a highly motivated individual who wants to work at a world-class institution with state-of-the-art facilities and learn from investigators at the forefront of their fields, consider advancing your research training at St. Jude.

Application Deadline: Open Until Filled

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17. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Rosch lab is looking for a postdoctoral scientist with an interest in host-pathogen interactions and/or antibiotic resistance. We are I looking for candidate with a PhD in Microbiology, Molecular Biology, or related field. Ideal candidates will have proven expertise in bacterial genetics, molecular techniques, and/or pathogenesis studies and excellent communication skills. Individuals should have the ability to work collaboratively in a fast-paced research environment. Research will focus on understanding the genetic basis of antibiotic resistance in Streptococcus pneumoniae as well as mechanistic studies of virulence.

Application Deadline: Open Until Filled

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18. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Immunology postdoctoral positions are available in the laboratory of Dr. Hongbo Chi in the Department of Immunology, St. Jude Children’s Research Hospital. The Chi lab investigates immunobiology and cancer immunology, by focusing on metabolic regulation of the immune system (immunometabolism) and its implications in cancer and other diseases. As metabolic pathways are inextricably connected to immunity and cancer, understanding these connections allows us to gain new insights into biological concepts and disease targets. We are particularly interested in understanding the metabolic programs (e.g. amino acid and lipid metabolism), signaling pathways (e.g. mTOR and nutrient-induced signaling), and systems-level regulatory networks (e.g. protein–protein or driver gene–target gene interactions) that regulate basic T cell and dendritic cell biology and antitumor immunity.

Application Deadline: Open Until Filled

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19. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Tsai Laboratory is seeking dynamic and creative candidates for a fully supported postdoctoral fellowship on genome editing technologies for therapeutic treatment of genetic disorders. CRISPR genome editors, adapted from bacterial adaptive immune systems, are transforming both basic biological research and genomic medicine. At St. Jude, we are working toward advancing these technologies towards patient treatments for sickle cell disease and bone marrow failure disorders.

Application Deadline: Open Until Filled

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20. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Chen Lab studies: i) Chemical modulation of transcription; ii) Signal crosstalk among transcription factors; and iii) Selective inhibition of highly homologous enzymes. We take a hypothesis-driven and technology-enabled multidisciplinary approach to develop chemical probes and investigate biological mechanisms. Particularly we use the promiscuous xenobiotic nuclear receptors (PXR and CAR) as models to investigate the transcription networks that regulate therapeutic responses. PXR and CAR regulate the detoxification system (e.g., by transcriptionally controlling CYP3A4 and CYP3A5—drug-metabolizing enzymes that metabolize more than 50% of clinical drugs), the dysregulation of which contributes to drug toxicity and drug resistance.

Application Deadline: Open Until Filled

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21. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Crispino’s laboratory studies the biology of normal and malignant hematopoiesis with an emphasis on the factors that drive progression of benign disorders to acute leukemia. Research in the lab ranges from the basic science of transcription to translational research aimed at developing treatments for blood disorders. A current major focus of the lab is to understand the increased risk of leukemia in children with Down syndrome and the role of GATA1 mutations and DYRK1A in oncogenesis. Another area of intense study is defining the mechanisms by which myeloproliferative disorders and myelodysplastic syndrome progress to acute myeloid leukemia. Finally, there is a major effort to understand the role of GATA1 in erythropoiesis.

Application Deadline: Open Until Filled

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22. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral position is available in the Derecka Lab in the Department of Hematology at St. Jude Children’s Research Hospital to study transcriptional regulation of the bone marrow niche. The major research goal of our group is to gain mechanistic insights into cellular cross communication between bone marrow microenvironment and hematopoietic compartment, in steady state and pathophysiological conditions. You will have the opportunity to develop new exciting projects involving changes of bone marrow microenvironment and its impact on aging blood system; transcriptional dysregulation of bone marrow niche in hematological disorders and bone marrow niche-induced changes of chromatin landscape in hematopoietic progenitors. In this position, you will have a chance to lead your projects and mature into fully independent researcher.

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23. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

An exciting career opportunity is available for a postdoctoral researcher in the laboratory of Dr. Andrew Davidoff to explore novel gene therapy and small molecule techniques in the treatment of solid tumors. The Davidoff lab seeks an inventive researcher to develop novel gene therapy vectors and test them in our translational models of neuroblastoma and liver cancers. The ideal candidate will have experience with models of solid tumors and/or AAV-based gene therapy vectors, to seek innovative cures for rare pediatric cancers.

Application Deadline: Open Until Filled

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24. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A wet-lab postdoctoral position is available immediately in the Northcott Lab (Department of Developmental Neurobiology) to join a highly collaborative team studying the developmental and molecular basis of the childhood brain tumor medulloblastoma. The Northcott Lab has established an internationally renowned track record in pediatric neuro-oncology, substantiated by numerous impactful publications in Nature, Cancer Cell, Lancet Oncology, and Journal of Clinical Oncology. Leveraging our exquisite access to patient material linked to large clinical trial cohorts, we are applying a combination of innovative, multi-omic approaches to discover new biological, mechanistic, and clinical insights responsible for medulloblastoma initiation, progression, and relapse.

Application Deadline: Open Until Filled

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25. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Advance hope, medical science, statistical science, and your career as a postdoctoral fellow in the Department of Biostatistics at St. Jude Children’s Research Hospital. A Ph.D. in statistics, biostatistics, computer science, or closely related field is required. Appointment is for two years. Applicants must have a strong computational background and demonstrate excellent written and verbal communication skills.

Application Deadline: Open Until Filled

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26. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral position is available in the Chang lab in the Department of Cell & Molecular Biology at St. Jude Children’s Research Hospital. We are looking for highly talented, self-motivated individuals passionate about how organelles communicate. In particular, the candidate will interrogate the fundamental questions of ER-to-Golgi trafficking via cutting-edge light and electron microscopy, genome-editing, biochemistry and in vitro reconstitution approaches.

Application Deadline: Open Until Filled

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27. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are seeking a highly motivated Postdoc Research Associate to join Dr. Ji Sun’s lab at St. Jude Children’s Research Hospital. Successful candidates will lead research projects focusing on disease-causing protein complexes, using an integrative approach combining structural, biochemical, and cell biology methods (Myasnikov A et al., Cell 2021; Zhu H et al., Biorxiv 2022, Jiang M et al., Cell Research, 2023).

Application Deadline: Open Until Filled

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28. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Obeng Laboratory is seeking creative and highly motivated candidates for a fully supported postdoctoral fellowship studying the pathogenesis of myeloid malignancies. The major interests of the lab are determining how acquired mutations in hematopoietic stem cells lead to the development of clonal hematopoiesis, myelodysplastic syndrome, and leukemia, in addition to identifying and studying novel treatments that selectively target malignant clones.

Application Deadline: Open Until Filled

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29. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Exciting postdoctoral positions are available immediately Solecki lab at St. Jude Children’s Research Hospital for talented and highly motivated individuals interested in understanding the cell biology of neuronal polarity or the regulation of nuclear architecture during neuronal differentiation. The Solecki Lab takes a multidisciplinary approach via cutting edge imaging technologies like lattice light sheet (LLS) microscopy or correlative super-resolution electron microscopy (CLEM) and computational approaches to mechanistically analyze the molecular and cellular mechanisms controlling neuronal differentiation, migration, and polarization.

Application Deadline: Open Until Filled

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30. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Bikoff lab is seeking a highly motivated postdoctoral researcher interested in studying neural circuitry in mice. The fundamental goal of our research is to understand how neural circuits control movement. We approach this from multiple perspectives, using cutting-edge technologies to analyze the molecular diversity of spinal interneurons, explore how descending systems in the brain convey information to the spinal motor system, and define the functional roles of spinal interneurons in generating behavior.

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