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29 Postdoctoral Positions at Roswell Park Comprehensive Cancer Center, New York

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Roswell Park Comprehensive Cancer Center, New York, USA invites multiple online application for Postdoctoral Positions in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.

1. Postdoctoral Positions 

Summary of Postdoctoral Fellowships:

A Postdoctoral Fellow/Associate position is available in the laboratory of Dr. Lori (Chia-Hsin) Chan in the Department of Molecular and Cellular Biology at Roswell Park Comprehensive Cancer Center. The appointment will start in July or later, 2021. We are seeking for self-motivated, collaborative individuals to join our group. The primary research will focus on studying the molecular basis that underlines tumor metabolism, metastasis, and immune responses. The candidate will have opportunities to participate the development of new therapeutic interventions used for cancer treatment. We will provide the new member the multidisciplinary training in molecular biology, cellular biology and various mouse model systems including xenograft, syngeneic and transgenic mice.

Application Deadline: Open Until Filled

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2. Post-doctoral Fellowship in Cancer Immunotherapy and GYN Cancer

Summary of Postdoctoral Fellowships:

A Postdoctoral position is open for a highly motivated candidate in the laboratory of Dr. AJ Robert McGray in the Department of Immunology. The project will focus on developing and optimizing strategies for the delivery of immune cell engagers (e.g. BiTEs) targeting the tumor and/or tumor stroma as potent cancer immunotherapies. The selected individual will use both in vitro systems and in vivo mouse models to develop, validate, and therapeutically test immune cell engagers. While a primary focus of this research will be to develop therapies that can be translated clinically to treat ovarian cancer, projects are anticipated to be broadly applicable to other tumor indications and will involve parallel studies in other disease areas.

Application Deadline: Open Until Filled

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3. Post-doctoral Research Affiliate in Immunotherapy

Summary of Postdoctoral Fellowships:

The laboratory of Dr. Renier Brentjens in the Department of Medicine is looking for a postdoctoral candidate to work on a research project aiming to generate novel chimeric antigen receptor (CAR) T cells specifically targeted to antigens for the treatment of cancer. The specific research project involves usage and identification of antigens for targeted cell therapies, CAR design, and experimental models to validate antitumor capacity. The selected individual will perform studies in human in vitro models (and potentially mouse in vitro and in vivo models) to validate and enhance ability of CAR T cells to be used as effective cell therapy. The experiments will involve the analyses of immune cell functions and may involve mouse models of cancer.

Application Deadline: Open Until Filled

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4. Post-doctoral Position in Pharmacogenetics

Summary of Postdoctoral Fellowships:

The laboratory of Dr. Andrew Goey is looking for a highly motivated and clinically oriented postdoctoral fellow to work on improving cancer treatments by pharmacogenetics. Research that will be carried out is highly translational and include genetic association studies, clinical trials, and in vitro drug metabolism experiments. The preferred candidate will have a track record of publications in the fields of pharmacogenetics and clinical pharmacology. Expected duties of the postdoctoral fellow include management and conduct of pharmacogenetic research projects, assistance in writing manuscripts, mentoring junior lab members, and applying for independent fellowship funding.

Application Deadline: Open Until Filled

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5. Post-doctoral Fellow in the Department of Pediatric Oncology

Summary of Postdoctoral Fellowships:

The Department of Pediatric Oncology is seeking a full time Postdoctoral Fellow in the laboratory of Dr. Nataliya Buxbaum. The Buxbaum lab focuses on immunometabolism as it relates to hematopoietic stem cell transplantation (HSCT) and cellular immunotherapies. Our bench-to-bedside laboratory and clinical investigations are centered on graft-versus-host disease (GvHD) with a goal of developing new imaging and therapeutic modalities for this condition (Assmann, J.C. et al. Blood, 2021 https://pubmed.ncbi.nlm.nih.gov/32785680/; Mhandire, K. et al. Metabolites, 2021 https://www.mdpi.com/2218-1989/11/11/736; Buxbaum, NP, et al. Journal of Clinical Investigation Insight, 2017 https://insight.jci.org/articles/view/92851).

Application Deadline: Open Until Filled

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6. Postdoctoral Positions 

Summary of Postdoctoral Fellowships:

The Goodrich lab at Roswell Park Comprehensive Cancer Center is looking for a highly motivated postdoctoral fellow to study prostate cancer lineage plasticity (see Ku et al. Science 2017, Mu et al. Science 2017, Pearson et al. Cancer Cell, 2021). The postdoc will work with a dynamic team of clinicians and scientists to perform both pre-clinical experiments and clinical trial correlative studies aimed at both understanding mechanisms underlying prostate cancer lineage plasticity and targeting them for therapeutic benefit.

Application Deadline: Open Until Filled

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7. Postdoctoral Positions 

Summary of Postdoctoral Fellowships:

The Sung Lab at Roswell Park Comprehensive Cancer Center is seeking a postdoctoral fellow to study therapeutic resistance to targeted therapy in acute myeloid leukemia. Dr. Sung has a joint appointment in the Department of Medicine (Leukemia Service) and the Department of Pharmacology & Therapeutics. The overall goal of the lab is to develop novel therapeutic strategies for translation to early phase clinical studies in AML. Our current focus is on FLT3 inhibition and its role in modulating the epigenetic state and myeloid differentiation in AML (supported by NCI K08).

Application Deadline: Open Until Filled

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8. Postdoctoral Positions 

Summary of Postdoctoral Fellowships:

A postdoc position is available immediately, in Dr. Sayan Chakraborty’s laboratory to study an exciting project that investigates the in-depth molecular and biochemical mechanisms of the oncogenic action of Agrin. The Chakraborty lab is commencing at Roswell Park in the summer of 2022. Previous studies from our group have shown that Agrin acts as a master regulator of mechanotransduction via YAP/TAZ activation and ‘outside-in communications’ via engagement of integrin-focal adhesion complexes in cancer cells. Using liver cancer models, we have recently observed that Agrin shapes up the mechanical landscape of the tumor microenvironment (TME) and modulates tumor angiogenesis by stabilizing VEGFR2.

Application Deadline: Open Until Filled

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9. Post-doctoral Position in Urology (Mind Maps Program)

Summary of Postdoctoral Fellowships:

We are seeking an enthusiastic and talented candidate with a Ph.D. in neuroscience, engineering, computer science, cognitive psychology, the biomedical sciences, or a field related to neuroscience to join the Mind Maps Project at the Applied Technology Laboratory for Advanced Surgery (ATLAS) Program at Roswell Park Comprehensive Cancer Center in Buffalo, NY. We are planning to start a new artificial intelligence lab at Roswell Park and this candidate will be actively involved in this initiative.

Application Deadline: Open Until Filled

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10. Post-doctoral Position in Urology (Bladder Cancer Program)

Summary of Postdoctoral Fellowships:

We are seeking an enthusiastic and talented candidate with a Ph.D. in cancer biology, genetics, molecular biology, experimental therapeutics, bioinformatics or related field. Perform a variety of routine and specialized lab tests and experimental procedures. Have access to patient database, tissue specimen, cell culture, patient-derived xenograft, next-generation sequencing and genetic mouse model.

Application Deadline: Open Until Filled

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11. Post-doctoral Position in GI/Internal Medicine (Note: Candidate must be externally funded by grant or institution)

Summary of Postdoctoral Fellowships:

We are interested in medical students or postgraduate medical trainees wanting to establish an academic career in surgery/surgical specialties in the United States. This will be a 2-year position with an option to extend further as needed. Funding for salary will not be provided unless the applicant is successful in obtaining grant funding. We can provide limited help with travel and accommodations. We will provide access to extensive resources while on campus carrying on research activities.

Application Deadline: Open Until Filled

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12. Post-doctoral Position in Center for Immunotherapy

Summary of Postdoctoral Fellowships:

Our laboratory studies and develops adoptive T cell therapies targeting solid tumors. The postdoctoral scientist will focus on developing genetically engineered T cells starting from the molecular cloning phase of cell therapy development, and then advancing to preclinical in vitro work and clinically relevant mouse models. A strong background in immunology and molecular biology will allow the successful applicant to be creative within the lab, enhancing T cell function and tumor targeting for optimal patient translation and high impact publication.

Application Deadline: Open Until Filled

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13. Postdoctoral Position in Breast Oncology Research

Summary of Postdoctoral Fellowships:

Position #1 is focused on studying the role of retinoblastoma tumor suppressor pathway (RB, p16ink4a, and cyclin D1) in breast cancer. Specific emphasis will be placed on the role of RB loss in disease progression and therapeutic response. This work will incorporate the use of cell culture, animal models, and clinical specimens. Position #2 is focused on deciphering mechanisms through which breast cancers evade standard therapies and elucidate new approaches for therapeutic intervention using targeted approaches. These studies will use PDX, organoid, and mouse models.

Application Deadline: Open Until Filled

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14. Postdoc in Indigenous Cancer Research: Environmental Cancer Health Disparities

Summary of Postdoctoral Fellowships:

The connection between Indigenous peoples and the natural environment has important ancestral, historical, cultural, and health related elements. The Roswell Park Center for Indigenous Cancer Research seeks a postdoc to collaborate in project(s) development across tribal areas dedicated to environment, human exposure and the human condition as they relate to cancer health issues and population science. We seek applications from a researcher who has worked and has experience with Indigenous populations, bench or basic science, cancer health disparities, and environmental research.

Application Deadline: Open Until Filled

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15. Post-doctoral Fellowship in Cancer Metabolism, Transcription and Metastasis Research

Summary of Postdoctoral Fellowships:

Postdoctoral position is open for highly motivated candidates in the laboratory of Dr. Subhamoy Dasgupta at the Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, NY- a National Cancer Institute (NCI) designated comprehensive cancer center. The Dasgupta lab focuses on discovering novel tumor metabolic adaptations, and investigates associated biological mechanisms such as transcriptional regulation, nuclear receptor and steroid hormone action, nutrient signaling, mitochondrial biology, epigenetics, and tumor immunology in the progression of cancer metastasis.

Application Deadline: Open Until Filled

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16. Postdoctoral Position Cell Cycle Control in Cancer

Summary of Postdoctoral Fellowships:

Postdoctoral position is open for highly motivated candidates in the laboratory of Dr. Erik Knudsen in the Center for Personalized Medicine, Roswell Park Comprehensive Cancer Center, NY- a National Cancer Institute (NCI) designated comprehensive cancer center. The Knudsen lab focuses on distinct features of the cell cycle including the RB-pathway, DNA replication control, and chromosome instability. State of art facilities such as genomics, multiplexed imaging, and sophisticated cancer models are widely used in the laboratory. Multiple models systems, including Genetically Engineered Mouse Models (GEMMs), patient-derived xenograft (PDX), and syngeneic tumor models are used to address challenging mechanisms in cancer. Currently the laboratory is stably funded by multiple grants from NIH/NCI and other funding sources.

Application Deadline: Open Until Filled

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17. Postdoctoral Position in Breast Cancer Research at Roswell Park Cancer Center

Summary of Postdoctoral Fellowships:

The postdoctoral position is focused on the biology, genetics, and treatment of breast cancer. This work is focused on using preclinical models of disease to develop new insights into disease progress/therapeutic resistance and elucidate novel targets therapeutic intervention. This work will employ an integrated analysis of functional studies, clinical specimens, and patient-derived models. Ideal candidates will have experience with cancer research and have a track record of leading projects to publication. Postdoctoral fellows will be expected to direct independent projects in a multi-disciplinary setting, assist in mentoring junior lab members, and apply for independent fellowship funding.

Application Deadline: Open Until Filled

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18. Postdoctoral Positions 

Summary of Postdoctoral Fellowships:

Our laboratory is broadly interested in transcriptional regulation and cell-fate determination in cancer cell biology and treatment. We are seeking a highly motivated and skilled candidate to work on a novel family of transcriptional and cell-fate regulators in cancer cell biology and treatment response, and stem cell biology. The candidate will be surrounded by a stimulating research environment, cutting-edge technology, and daily interactions with colleagues in other labs. The training environment will be one where regular discussion of new ideas, and freedom to explore new avenues of investigation, will be encouraged.

Application Deadline: Open Until Filled

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19. Postdoctoral Position in Molecular and Genetic Cancer Epidemiology at Roswell Park Comprehensive Cancer Center

Summary of Postdoctoral Fellowships:

A research group at Roswell Park Comprehensive Cancer Center Department of Cancer Prevention and Control (Buffalo, NY) is looking for a postdoctoral research fellow, who is interested in academic research of cancer epidemiology, genomics, and cancer health disparities. The group is dedicated to cutting-edge population-based research to understand the biological underpinnings of cancer racial/ethnic disparities, with multiple active federal and private foundation funded research projects focusing on genomic, molecular, and cellular mechanisms underlying cancer health disparities in several large and unique racial/ethnic minority populations, as well as on cancer outcome and survivorship.

Application Deadline: Open Until Filled

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20. Post-doctoral Fellow in Myeloma

Summary of Postdoctoral Fellowships:

The Multiple Myeloma/Amyloidosis Service of the Department of Medicine is seeking a full-time Postdoctoral Fellow in the laboratory of Dr. Jens Hillengass. The Hillengass lab focuses on the spatial heterogeneity of bone marrow infiltration of multiple myeloma. Using modern genomic DNA and RNA sequencing approaches as well as immunological analyses Dr. Maximilian Merz was able to show genes being differentially expressed in osteolytic lesions compared to the random bone marrow. Longitudinal samples showed transcriptional changes after treatment.

Application Deadline: Open Until Filled

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21. Post-doctoral Postiton Medicine Dept. (Leukemia Service)

Summary of Postdoctoral Fellowships:

A postdoc position is immediately available to study the biology of acute leukemia and perform preclinical evaluation of promising therapeutic approaches for acute leukemia. Candidates should be highly motivated and able to work independently in designing, performing, and analyzing experiments. Experience in data presentation (oral/poster) and writing skills are highly desired. Proficiency in laboratory skills includes flow cytometry, fluorescent microscopy, in vitro proliferation/cytotoxicity assays, western blots, RNA/DNA extraction and other molecular biology techniques are required. Candidates with prior experience working on tumor mouse models are preferred (but not required).

Application Deadline: Open Until Filled

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22. Post Doctoral Position Cancer Genetics & Genomics

Summary of Postdoctoral Fellowships:

The project will study the role of the HBP1-BRMS1-BRMSL1 axis in controlling breast cancer dormancy in the bone microenvironment. The project involves an in vitro 3D culture model that recapitulates bone endosteal or vascular niche microenvironments. As well, the project involves in vivo spontaneous and experimental breast cancer bone colonization models (orthotopic and intracardiac injections), in vivo monitoring of metastatic growth and signaling in the bone, and analysis of how the HBP1-BRMS1-BRMSL1 axis controls cell cycle progression genes through the SIN3A-mediated chromatin landscape.

Application Deadline: Open Until Filled

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23. Postdoctoral position in Molecular Epidemiology with Dr. Li Tang At Roswell Park Cancer Institute

Summary of Postdoctoral Fellowships:

A post-doctoral position in molecular epidemiology is available in the research program of Li Tang, PhD. Dr. Tang is an Associate Professor in the Department of Cancer Prevention and Control at Roswell Park Cancer Institute, Buffalo, NY. The fellow will work closely with Dr. Tang and with intramural and extramural collaborators. The research questions of interest include: 1) How do diet and genes interact to affect cancer treatment outcomes? 2) How do genetic variants contribute to racial differences in cancer characteristics and prognosis? 3) What is the role of human endogenous retrovirus in cancer development? The fellow will be mentored with an emphasis on analytic, writing, and other research skills in order to facilitate his/her transition to an independent investigator.

Application Deadline: Open Until Filled

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24. Post-doctoral Position in Cancer Genetics & Genomics

Summary of Postdoctoral Fellowships:

Identification and Functional Analysis of Novel Genetic Interactions and Vulnerabilities in KRAS Mutant Solid Tumors. The Cancer Genetics and Genomics Department at Roswell Park Cancer Institute is searching for an ambitious PhD biologist for a postdoctoral research project in the Identification and Functional Analysis of Novel Genetic Interactions and Vulnerabilities in KRAS Mutant Solid Tumors. Projects will be oriented around one or some combinations of the following topics: identification and characterization of novel tumor suppressor genes and/or oncogenes; and the study of their dysfunction mechanisms (focusing on epigenetics and tumor metabolism) in lung cancer and/or pancreatic cancer (e.g., using cell culture, animal models).

Application Deadline: Open Until Filled

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25. Translational Glycomics Postdoc Training Program

Summary of Postdoctoral Fellowships:

The Translational Glycomics K12 program is currently accepting and considering applications from outstanding and motivated scholars. This program is intended for MD, MD/PhD, and PhDs at postdoctoral level for career development into independently funded researchers specializing in translational glycosciences. Each scholar is required to spend at least 2 years, limited to 3 years in the program. Each applicant will be evaluated independently, and program designed on an individual basis. Clinical MD’s must be able to devote 75% or greater time into the Program.

Application Deadline: Open Until Filled

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26. Post-Doctoral Position in Molecular and Cellular Biology

Summary of Postdoctoral Fellowships:

Identification and functional analysis of novel glycan-based cell – niche interactions in blood cell production and function. The Molecular and Cellular Biology Department at Roswell Park Cancer Institute is searching for an ambitious PhD, MD, or PhD-MD biologist for a postdoctoral research project in the Identification and functional analysis of novel glycan-based cell-niche interactions in blood cell production and function. Projects will be oriented around one or some combinations of the following topics: identification and characterization of novel cell-niche in maintenance of hematopoietic stem cells; and the study of disruption to healthy hematopoiesis by normal cells neighboring malignant and pre-malignant neoplasms; role of glycans in the tumor and cancer stem cell niche.

Application Deadline: Open Until Filled

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27. Cancer Genomics Post-Doctoral Position at Roswell Park (Bench-focus)

Summary of Postdoctoral Fellowships:

A grant-funded postdoctoral research affiliate position is available in the Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center. The focus of the research program is the genomics of tumor suppression due to endogenous and mutant X-linked cancer antigens. This position is ideal for a candidate with a strong biology background with significant solid technical experience. Our lab uses modern NGS techniques (bulk and single cell RNAseq), protein-protein methods and integrative genomics/bioinformatics and has expertise in comparative genetics and genetic epidemiology.

Application Deadline: Open Until Filled

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28. Cancer Genomics Post-Doctoral Position at Roswell Park (Informatics-focus)

Summary of Postdoctoral Fellowships:

This position is ideal for a researcher with a strong background in biology and interested in additional bioinformatics training. The incumbent will direct or manage independent projects in the bench portion of the laboratory feeding back into bioinformatics with the opportunity for increasing informatics responsibilities. Alternatively, applicants with terminal degrees in statistics, computer science, or data science with a demonstrated interest in cancer genetics and an interest in a career in cancer biology are encouraged to apply.

Application Deadline: Open Until Filled

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29. Post Doc or Research Associate position

Summary of Postdoctoral Fellowships:

Applications are sought for a Post-Doctoral or Research Associate position in the Department of Cancer Prevention and Control at Roswell Park Comprehensive Cancer Center. The candidate will take part in NIH-funded projects on HPV infection and related diseases in high-risk populations. Projects include a large HPV vaccine surveillance study of inner-city minority youth, and a prospective study of oral HPV and the microbiome in HIV+ individuals. The candidate is expected to analyze data, publish papers, assist with preparing grants, and help supervise graduate and undergraduate students. The position will be for a period of 2 years, with possibility of extension, and comes with a competitive salary and attractive benefits.

Application Deadline: Open Until Filled

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