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28 Postdoctoral Fellowships at City of Hope, California, United States

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Are you holding PhD degree and looking for Postdoctoral Fellowships? City of Hope, California, United States invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.

1. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Williams lab is looking for a highly motivated postdoctoral student interested in working in translational medicine to treat cancer. The overarching goals of the group are to identify and address unmet clinical needs (e.g., on-target, off-tissue toxicities) by rapidly translating novel molecular designs to the clinic. Using an atoms-up approach, our group pioneered the concept and development of tumor-activated IO monoclonal antibodies, leading the formation of Xilio Therapeutics which has two products currently in phase 1/2 clinical trials.

We also discovered and subsequently developed a unique peptide-Fab interaction that allows us to rapidly functionalize monoclonal antibodies including antibody-drug conjugates, bispecifics including NK and T cell engagers, antibody-based imaging reagents, and switchable CAR T cells. Given these successes, we have broadly expanded our efforts including the discovery of novel antibodies, combining single cell techniques (enabled by the acquisition of a Berkeley Lights Beacon) with structural and computational biology efforts.

Application Deadline: Open Until Filled

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2. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr Ed Boas, at the Beckman Research Institute of City of Hope, a prestigious NCI-designated Comprehensive Cancer Center. We are looking for a biomedical engineer, materials scientist, immunologist, or cancer biologist who can help us develop new minimally invasive cancer therapies, such as new materials or devices for drug delivery into tumors (percutaneous or intra-arterial). We are one of the few interventional oncology groups in the United States with a basic science lab, large animal tumor model, and several active clinical trials, which enables us to translate new discoveries from bench to animal to bedside.

Application Deadline: Open Until Filled

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3. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow position is available in the laboratory of Edwin R. Manuel, PhD, at City of Hope, Beckman Research Center, Monrovia, CA. Our lab is interested in utilizing tumor-colonizing, bacterial-based agents as novel immunotherapy for solid and hematologic malignancies. We are recruiting enthusiastic, motivated scientists who are seeking a fast-paced academic research environment. Our lab in the Department of Immuno-Oncology focuses on engineering tumor-colonizing bacteria to target components of the tumor microenvironment that contribute poor drug delivery, immune suppression and cancer metabolism.

Application Deadline: Open Until Filled

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4. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. ZJ Sun at Beckman Research Institute of City of Hope, one of a prestigious group of NCI-designated Comprehensive Cancer Centers. The candidate will directly work on the novel and ongoing projects on prostatic stem cells and stem cell niches in prostate development and tumorigenesis using “cutting edge” and unbiased analytic tools and unique and innovative genetically engineered mouse models (please see some of the recent publications: PLoS Genet 2020 Jan 13:16(1):e1008588; Development 2021 Jan 11:148(1):dev196048; Development 2021 Oct 1:148(19):dev199738; Nat Commun 2022 Jul 28:13:4364; Nat Commun 2022 Nov 2:13:6552).

Application Deadline: Open Until Filled

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5. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the research group of Dr. Sumanta Pal, at the Beckman Research Institute and Department of Medical Oncology of City of Hope, a prestigious NCI-designated Comprehensive Cancer Center. The candidate will directly work on projects focused on genitourinary cancers, specifically kidney, bladder, and prostate cancers. This includes developing and maintaining clinical and translational research trials in genitourinary cancers, collecting, analyzing, and maintaining large databases pertaining to genitourinary cancers, drafting original research and review articles and publishing in peer reviewed journals, and developing and presenting abstracts at national and international conferences.

Application Deadline: Open Until Filled

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6. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The laboratory of Javier Gordon Ogembo, Ph.D.at The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. Our laboratory invites highly motivated candidates to apply for an interdisciplinary postdoctoral fellow position. Our laboratory focuses on oncogenic herpesviruses, in particular Epstein-Barr virus (EBV), Kaposi-sarcoma associated herpesvirus (KSHV), and the rhesus macaque EBV homologue rhesus lymphocryptovirus (rhLCV), and on developing prophylactic and therapeutic strategies against primary infection with these viruses and their associated cancers.

Application Deadline: Open Until Filled

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7. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral position is now available in the laboratory of Dr. Yilun Liu at the Department of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope. Dr. Liu’s research topics include:

  • Dissecting the molecular mechanism by which transcription-associated genomic instability and epigenetic deregulation contribute to developmental abnormalities and cancer
  • Developing pharmaceutical mechanisms for cancer therapy by targeting enzymes important for preventing the formation of DNA breaks arose during accelerated cell growth such as in cancer cells as well as factors important for the BRCA2 and PARP-dependent repair pathways to keep these DNA breaks unrepaired

Application Deadline: Open Until Filled

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8. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. June-Wha Rhee in City of Hope’s Department of Medicine, Division of Cardiology. The lab’s research focuses on understanding the biology underlying cancer therapy-induced cardiovascular complications by leveraging human-induced pluripotent stem cells (iPSCs) as well as patient samples, genomics and leading-edge computational biology.

Application Deadline: Open Until Filled

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9. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are looking for a talented and highly motivated Postdoctoral Fellow, to join the Laboratory for Cellular Medicine (LCM), Center for Gene Therapy at the Beckman Research Institute of City of Hope. The candidate will join a well-established group performing cutting-edge research, development and qualification of large-scale processes, and manufacture of products for gene therapy clinical trials, including first-in-human studies with genetically engineered (ge) hematopoietic stem and progenitor cells (HSPC) and T cells.

Application Deadline: Open Until Filled

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10. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Mingye Feng’s laboratory at the Beckman Research Institute of City of Hope is looking for a talented and highly motivated Postdoctoral Fellow. Dr. Feng is an awardee of the V Scholar Award from the V Foundation for Cancer Research, the Damon Runyon – Dale F. Frey Award for Breakthrough Scientists from the Damon Runyon Cancer Research Foundation, the K99/R00 Pathway to Independence Award from NIH, and NIH R01 grants. His laboratory employs cutting-edge techniques to understand mechanisms of macrophages in cancer immunosurveillance, identify immune checkpoints and ligands on various hematopoietic malignant and solider tumor cells with high-throughput screening and protein engineering approaches developed in the lab, and develop novel cancer immunotherapies targeting metastatic cancer cells.

Application Deadline: Open Until Filled

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11. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Wang Laboratory at the Department of Systems Biology, Beckman Research Institute, City of Hope, is seeking for a talented and motivated Postdoctoral Fellow to lead the project for RNA splicing dysregulation and oncogenesis in blood malignancies. Candidates with strong background in RNA splicing, cancer biology, animal models, and bioinformatics are encouraged to apply. Wang Laboratory is currently funded by R01 and foundation grants.

Application Deadline: Open Until Filled

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12. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Shen laboratory has been focusing on DNA replication/repair pathway components, cancer genetics and epigenetics, and cancer etiological and therapeutics modeling. The laboratory is seeking additional members to work on several new projects. Recent Ph.D. graduates or equivalents in the field of biological/medical sciences with ambition for a scientific career and interest in DNA replication and repair, genome stability, and cancer biology and skills in molecular biology, genetics or biochemistry are encouraged to apply. Bioinformatics and data mining skills are a plus for considerations.

Application Deadline: Open Until Filled

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13. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Caligiuri/Yu Laboratory at Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. We are a fast-paced lab involved in cutting-edge technology, research and clinical immunotherapy investigations. We are currently looking for a postdoctoral fellow who will develop chimeric antigen receptor T- and NK-cell therapies in combination with oncolytic viruses for the treatment of solid tumors, especially glioblastoma. The PhD candidate should have experience in the fields of immunology and cancer biology with a strong track record. This position will interact and collaborate with a team of researchers with similar interests in developing cell-based therapies in a translational research environment.

Application Deadline: Open Until Filled

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14. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our group is interested in discovering novel genetic and epigenetic regulations and deciphering their underlying molecular mechanisms in normal developmental processes (e.g., hematopoiesis) and tumorigenesis (e.g., leukemogenesis). We cover research areas with relevance to Hematology, Immunology, and Cancer Biology, with an emphasis on RNA epigenetics (mainly focusing on the N6 methyladenosine (m6A) modification) and DNA epigenetics (mainly focusing on the TET1/2/3-mediated DNA demethylation) associated basic and translational research. Our research involves experiments with primary human cancer cells, cancer and stem cell transplantation models, mouse genetics, classic molecular, biochemistry and cell biology, functional genomics, signal transduction, and large-scale data analysis and computational biology.

Application Deadline: Open Until Filled

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15. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are seeking a talented and motivated Postdoctoral Fellow within the multidisciplinary research team headed by Drs. Nagarajan Vaidehi, Andrei S. Rodin, and Sergio Branciamore at the Department of Computational and Quantitative Medicine (chaired by Dr. Vaidehi) at the Beckman Research Institute of City of Hope. Our research group comprises computational biologists, computational chemists, and bioinformaticians, with a notable record of productivity and publishing in high-impact journals.

Application Deadline: Open Until Filled

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16. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Alexey Danilov’s research is focused on the mechanisms of lymphomagenesis and identification of novel therapeutic targets in B-cell lymphoma and other cancers. Following our recent laboratory discoveries, we also explore the immunomodulatory effects of novel targeted agents and aim to harness their potential to enhance the efficacy of immunotherapy and novel cellular therapies. We are looking for a Postdoc to advance one of the following areas of interest in our laboratory:
– immunomodulatory effects of targeted agents and mechanism-driven approaches to enhance efficacy of immune and cellular therapies;

Application Deadline: Open Until Filled

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17. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We currently have multiple Postdoctoral Fellowship positions within the multidisciplinary research team headed by Dr. Ajay Goel, Professor and Chair, Department of Molecular Diagnostics and Experimental Therapeutics and Associate Director of Basic Sciences, City of Hope Comprehensive Cancer. Our multidisciplinary research group comprises of basic biologists, gastroenterologists, surgeons, oncologists and bioinformaticians, undertaking a number of collaborative projects involving large international consortia.

Our research is focused on translational research as it relates to genomic and epigenomic characterization of various gastrointestinal cancers (GI) including colorectal, pancreatic and gastric cancers, and some of the key research topics include: 1) Development of circulating DNA/RNA-based liquid biopsy biomarkers for cancer diagnosis, prognosis and predictive response to various therapies. 2) Study the epigenetic basis of GI cancers (e.g. aberrant DNA methylation, histone modifications and non-coding RNAs. 3) The genetic basis of early-onset and familial/hereditary colorectal cancers. 4) The role of tumor microenvironment, stem cells, immune regulation and identification of novel targeted therapies. 5) The role of extracellular vesicles/exosomes as in cancer pathogenesis and their role as disease biomarkers.

Application Deadline: Open Until Filled

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18. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are seeking a talented and motivated Postdoctoral Fellow within the multidisciplinary research team headed by Dr. Ajay Goel, Professor and Chair, Department of Molecular Diagnostics and Experimental Therapeutics and Associate Director of Basic Sciences, City of Hope Comprehensive Cancer. Our research group comprises of basic biologists, gastroenterologists, surgeons, medical oncologists and bioinformaticians, undertaking a number of collaborative projects involving large international consortia.

Application Deadline: Open Until Filled

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19. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Ngo laboratory at the Department of Systems Biology, City of Hope is seeking a highly motivated Postdoctoral Fellow to lead a federally funded project in lymphoma and immunotherapy. Our laboratory studies molecular mechanisms and identifies therapeutic targets in hematologic malignancies. Candidates having interests in cancer biology and immunology with hands-on experience in working with hematopoietic cells and handling animals are encouraged to apply. Candidates with at least one first-author paper will be given more priority.

Application Deadline: Open Until Filled

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20. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral fellow position in Computational Biology is immediately available under the direction of Dr. Vaidehi Nagarajan – Chair, Dept. of Computational & Quantitative Medicine at Beckman Research Institute. This project involves development and application of large scale data analysis techniques from the Systems Biology field to molecular dynamics methods, and the study of the dynamics of G-protein coupled receptors complexes to understand its signaling selectivity. The project is inter-disciplinary and provides opportunities to train in large scale data analysis techniques as well as interact with experimental collaborators. City of Hope provides a multi-disciplinary collaborative environment with opportunities to interact with clinician scientists to conduct bench side to bedside research.

Application Deadline: Open Until Filled

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21. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We currently have a Postdoctoral Fellowship position within a research team headed by Dr. Jeff Perry, Assistant Professor, Department of Molecular Diagnostics and Experimental Therapeutics, and member of the City of Hope Comprehensive Cancer. We are looking for a post-doctoral candidate with experience in protein crystallography. A Ph.D. in Biochemistry, Biophysics or a related discipline is required. The Perry laboratory uses structural biology approaches, together with small molecule and fragment-based drug discovery, computer-aided drug discovery approaches and biochemical assays to target key proteins. This funded position is for a postdoctoral trainee interested in aiding the development of therapeutic against both type 1 and type 2 diabetes mellitus.

Application Deadline: Open Until Filled

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22. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Postdoctoral Fellow position is available immediately in the laboratory of Dr. Christiane Querfeld, M.D., Ph.D. at Beckman Research Institute of City of Hope. Christiane Querfeld, M.D., Ph.D., director of the Cutaneous Lymphoma Program, seeks better treatment options for cutaneous T cell lymphoma (CTCL), a rare form of lymphoma that first appears on the skin but can also spread to lymph nodes and internal organs. City of Hope is one of the few institutions in the country that offers clinical trials to treat cutaneous lymphomas. Dr. Querfeld leads a multidisciplinary team of experts, including medical and radiation oncologists, pioneering treatments for CTCL and its subtypes.

Application Deadline: Open Until Filled

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23. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Postdoctoral positions are now available in the laboratory of Dr. Yilun Liu at the Department of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope. Dr. Liu’s research topics include:

  • Dissecting the molecular mechanism by which transcription-associated genomic instability and epigenetic deregulation contribute to developmental abnormalities and cancer.
  • Developing pharmaceutical mechanisms for cancer therapy by targeting enzymes important for preventing the formation of DNA breaks arose during accelerated cell growth such as in cancer cells as well as factors important for the BRCA2 and PARP-dependent repair pathways to keep these DNA breaks unrepaired.

Application Deadline: Open Until Filled

More Details

 

24. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Join our successful and productive research team at the Beckman Research Institute at City of Hope where we are studying the biological mechanisms of breast cancer susceptibility in the context of aging. This current position is focused on using cell and molecular techniques to examine emergent mechanical properties of epithelial cells that are highly susceptible to breast cancer initiation.

This mechanobiology work is the product of a long-term, NIH funded, collaboration with a bioengineering group at UC Berkeley. We are using, and evolving, a mechano-node pore sensing (mechano-NPS) platform to explore unique mechanical properties of cells that are associated with chronological or biological age, lineage, and cancer progression stage. We hypothesized that mechano-NPS can detect disease states based on the emergent mechanical properties that arise from the underlying molecular networks that define lineage and disease states.

Application Deadline: Open Until Filled

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25. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. The Williams Research Team seeks a self-motivated, results-driven postdoc to drive the development of the generation of therapeutic monoclonal antibodies. Expertise required include thorough knowledge of protein engineering (cloning, expression, purification), crystallography (crystallization, optimization, data collection and structure determination), biochemistry (enzyme kinetics) and biophysics (Surface Plasmon Resonance, Iosthermal Ttitration Calorimetry, etc).

Application Deadline: Open Until Filled

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26. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Nadia Carlesso’s research is focused on the mechanisms of leukemogenesis and identification of novel therapeutic approaches in poor prognosis T-ALL. Following recent laboratory discoveries, her group is exploring novel approaches to target the microenvironment/oncogene cooperation driving chemoresistance and relapse in T-ALL leukemia stem cells. This project is nested on a larger program directed by Dr. Carlesso that focuses on the relationships between the tumor microenvironment, inflammation, and stem cell biology in hematopoietic diseases.

Application Deadline: Open Until Filled

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27. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow Position is available in the laboratory of Dr. Tijana Jovanovic-Talisman. Biological nanoparticles that are continuously shed by cells – namely extracellular vesicles (EVs) – are an emerging and exciting strategy for performing minimally invasive diagnoses. Because EVs are loaded with disease-specific molecules, they represent an excellent source of biomarkers. The project involves employing cell biology and super-resolution microscopy approaches to characterize extracellular vesicles that contain disease-specific or tissue-specific molecules. Ultimately, the goal is to develop a new platform to perform molecular level diagnoses for precision medicine.

Application Deadline: Open Until Filled

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28. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Yanhong Shi’s lab is looking for highly motivated and productive postdoctoral fellows for stem cell research projects within the Department of Stem Cell Biology and Regenerative Medicine (Shi laboratory) at Beckman Research Institute of City of Hope located in the county of Los Angeles, California. Candidates interested in this position are encouraged to submit curriculum vitae, brief statement of interests and a list of three references. The Shi laboratory has been well known for stem cell research, including stem cell-based disease modeling and cell therapy development. This laboratory is one of the pioneers in establishing disease models and cell therapies using the human induced pluripotent stem cell (iPSC) platform and has published extensively in this area.

Application Deadline: Open Until Filled

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