Are you holding PhD degree and looking for Postdoctoral Fellowships? Roswell Park Comprehensive Cancer Center, Buffalo, New York invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.
1. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A Postdoctoral position is open for a highly motivated candidate in the laboratory of Dr. AJ Robert McGray in the Department of Immunology. The project will focus on developing and optimizing strategies for the delivery of immune cell engagers (e.g. BiTEs) targeting the tumor and/or tumor stroma as potent cancer immunotherapies. The selected individual will use both in vitro systems and in vivo mouse models to develop, validate, and therapeutically test immune cell engagers. While a primary focus of this research will be to develop therapies that can be translated clinically to treat ovarian cancer, projects are anticipated to be broadly applicable to other tumor indications and will involve parallel studies in other disease areas.
Application Deadline: Open Until Filled
2. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The laboratory of Dr. Renier Brentjens in the Department of Medicine is looking for a postdoctoral candidate to work on a research project aiming to generate novel chimeric antigen receptor (CAR) T cells specifically targeted to antigens for the treatment of cancer. The specific research project involves usage and identification of antigens for targeted cell therapies, CAR design, and experimental models to validate antitumor capacity. The selected individual will perform studies in human in vitro models (and potentially mouse in vitro and in vivo models) to validate and enhance ability of CAR T cells to be used as effective cell therapy. The experiments will involve the analyses of immune cell functions and may involve mouse models of cancer. The candidate will be involved in preparation of scientific manuscripts and grant applications, with the expectation of developing first author papers and contributing (as a co-author) to papers of other members of the team.
Application Deadline: Open Until Filled
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3. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Department of Pediatric Oncology is seeking a full time Postdoctoral Fellow in the laboratory of Dr. Nataliya Buxbaum. The Buxbaum lab focuses on immunometabolism as it relates to hematopoietic stem cell transplantation (HSCT) and cellular immunotherapies. Our bench-to-bedside laboratory and clinical investigations are centered on graft-versus-host disease (GvHD) with a goal of developing new imaging and therapeutic modalities for this condition.
Application Deadline: Open Until Filled
4. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Goodrich lab at Roswell Park Comprehensive Cancer Center is looking for a highly motivated postdoctoral fellow to study prostate cancer lineage plasticity (see Ku et al. Science 2017, Mu et al. Science 2017, Pearson et al. Cancer Cell, 2021). The postdoc will work with a dynamic team of clinicians and scientists to perform both pre-clinical experiments and clinical trial correlative studies aimed at both understanding mechanisms underlying prostate cancer lineage plasticity and targeting them for therapeutic benefit.
Application Deadline: Open Until Filled
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5. Postdoctoral Position
Summary of Postdoctoral Fellowship:
We are seeking an enthusiastic and talented candidate with a Ph.D. in neuroscience, engineering, computer science, cognitive psychology, the biomedical sciences, or a field related to neuroscience to join the Mind Maps Project at the Applied Technology Laboratory for Advanced Surgery (ATLAS) Program at Roswell Park Comprehensive Cancer Center in Buffalo, NY. We are planning to start a new artificial intelligence lab at Roswell Park and this candidate will be actively involved in this initiative.
Application Deadline: Open Until Filled
6. Postdoctoral Position
Summary of Postdoctoral Fellowship:
We are seeking an enthusiastic and talented candidate with a Ph.D. in cancer biology, genetics, molecular biology, experimental therapeutics, bioinformatics or related field. Perform a variety of routine and specialized lab tests and experimental procedures. Have access to patient database, tissue specimen, cell culture, patient-derived xenograft, next-generation sequencing and genetic mouse model.
Application Deadline: Open Until Filled
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7. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The laboratory of Dr. Marco Davila in the Department of Medicine is looking for a postdoctoral candidate to work on a research project aiming to generate novel chimeric antigen receptor (CAR) T cells specifically targeted to antigens for the treatment of cancer. The specific research project involves the usage and identification of antigens for targeted cell therapies, CAR design, and experimental models to validate antitumor capacity. The selected individual will perform studies using in vitro models to validate and enhance the ability of CAR T cells to be used as effective cell therapy. The experiments will also involve the analyses of immune cell functions and mouse models of cancer.
Application Deadline: Open Until Filled
8. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A Postdoctoral Fellow position is available in the laboratory of Dr. Ethan V. Abel in the Department of Molecular and Cellular Biology. Position offers independence as well as important collaborative opportunities. Research will focus on the functional characterization of transcriptional/epigenetic regulators and signaling proteins in pancreatic cancer, and how these cellular components regulate drug resistance, cancer stem cells, metastasis, and metabolism to drive the disease. The laboratory’s research places equal emphasis on basic, mechanistic discovery and translational/preclinical research.
Application Deadline: Open Until Filled
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9. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A postdoctoral position is immediately available in the laboratory of Karen McLean, MD, PhD, in the Gynecology Department at Roswell Park Comprehensive Cancer Center. Dr. McLean has a joint appointment in the Department of Pharmacology & Therapeutics, with laboratory space and access to shared resources in the Center for Genetics and Pharmacology Building. The McLean laboratory studies the pathogenesis of ovarian cancer, with projects focusing on the interplay between DNA damage repair and responses to immunotherapy as well as tumor microenvironment signaling.
Application Deadline: Open Until Filled
10. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Department of Immunology at Roswell Park Cancer Institute invites applications for a Postdoctoral Fellow or Research Assistant position to develop a novel platform technology that opens the possibility of multifunctional products, such as an engineered oncolytic vaccinia virus that selectively infects tumor cells, to be used as a vector for targeted delivery and expression of high concentrations of therapeutic (CXCR4-A-Fc antagonist of CXCR4 receptor) molecules in metastatic tumors. The overall objective of this study is to explore changes in the dynamic interactions between malignant and stromal cells that could potentially lead to inhibition of metastatic spread and unmask the patients’ own immunity for a long-term control of tumor growth by therapeutic vaccines and adoptively transfer T cells.
Application Deadline: Open Until Filled
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11. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The laboratory of Dr. Andrew Goey is looking for a highly motivated and clinically oriented postdoctoral fellow to work on improving cancer treatments by pharmacogenetics. Research that will be carried out is highly translational and include genetic association studies, clinical trials, and in vitro drug metabolism experiments. The preferred candidate will have a track record of publications in the fields of pharmacogenetics and clinical pharmacology. Expected duties of the postdoctoral fellow include management and conduct of pharmacogenetic research projects, assistance in writing manuscripts, mentoring junior lab members, and applying for independent fellowship funding.
Application Deadline: Open Until Filled
12. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Our laboratory studies and develops adoptive T cell (CAR T cell) therapies targeting solid tumors. The postdoctoral scientist will develop genetically engineered T cell therapies starting from the molecular cloning phase of cell therapy development, and then advancing to preclinical in vitro work and clinically relevant mouse models. A strong background in molecular biology and immunology will allow the successful applicant to be creative within the lab, enhancing T cell function and tumor targeting for optimal patient translation and high impact publication. The postdoctoral scientist will work under the co-mentorship of Leonid Cherkassky and Renier Brentjens, as well as additional leaders in immune therapies within the Division for Translational Immuno-oncology (DTIO). We have a rapidly advancing program engaged in cutting edge preclinical science and supported by a strong institutional commitment to translating cellular therapies to cancer patients.
Application Deadline: Open Until Filled
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13. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Liu lab at the Department of Pharmacology and Therapeutics at Roswell Park Comprehensive Cancer Center is seeking highly-motivated postdoctoral fellows with interests in RNA and/or cancer biology to join our efforts in fighting cancer. We employ a multi-disciplinary approach that combines in vivo mouse models, in vitro patient-derived organoids (PDOs), classical biochemistry, cutting-edge multi-omics techniques, and advanced bioinformatic analyses to discover key post-transcriptional mechanisms that govern cancer progression and metastasis. We aim to develop innovative therapeutic strategies, in particular RNA therapeutics, to translate these mechanistic insights into the clinic.
Application Deadline: Open Until Filled
14. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Postdoctoral positions are open for highly motivated candidates in the laboratory of Dr. Liya Ding in the Department of Immunology at Roswell Park Comprehensive Cancer Center. The research projects will focus on the interactions between cancer cells and the host immune system and the development of new treatments for ovarian and prostate cancer patients. We employ a multi-disciplinary approach that combines an in vitro coculture system of tumor and immune cells, in vivo syngeneic and humanized mouse models, CRISPR screening, scRNA-seq and advanced bioinformatic analyses. We seek to discover essential regulators of tumor immunity, including immunogenic cell death, antigen processing and presentation, dendritic cell and T cell activation and immunosuppression mediated by myeloid cells. We aim to develop mechanism-based innovative immunotherapies that can be translated into clinical practice to improve the outcomes of current treatment in cancers.
Application Deadline: Open Until Filled
15. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A postdoctoral position is available in the Atanassov Lab in the Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, New York. We are looking for a highly motivated, self-driven postdoctoral fellow to study the role of deubiquitinating enzymes (DUBs) in cancer. The postdoctoral fellow will work with a dynamic team of scientists and research fellows in an outstanding research environment and utilize genetically engineered mouse models and biochemical approaches to elucidate the molecular mechanisms of how DUB functions potentiate cancer growth and develop strategies for their therapeutic targeting. The study is supported by NIH funded R01 award, and the position is ready for an immediate start.
Application Deadline: Open Until Filled
16. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Das lab at Roswell Park Comprehensive Cancer Center is looking for a highly motivated postdoctoral fellow with a passion for research to study molecular mechanisms of breast cancer with emphasis on the crosstalk between estrogen receptors and p53 signaling. Translating lab findings to novel therapies will be a priority (see Mukhopadhyay et al. Journal of the National Cancer Institute (JNCI) 2019, Oturkar et al. Cancers 2022, Scarpetti et al. The Oncologist 2023).
Application Deadline: Open Until Filled
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17. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Postdoctoral positions are available in the laboratory of Dr. Dhyan Chandra, Pharmacology and Therapeutics. New postdoctoral fellows will study the role of mitochondria and heat shock proteins in prostate cancer biology and the development of therapeutic resistance in cancer.
Application Deadline: Open Until Filled
18. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The project will study the role of the HBP1-BRMS1-BRMSL1 axis in controlling breast cancer dormancy in the bone microenvironment. The project involves an in vitro 3D culture model that recapitulates bone endosteal or vascular niche microenvironments. As well, the project involves in vivo spontaneous and experimental breast cancer bone colonization models (orthotopic and intracardiac injections), in vivo monitoring of metastatic growth and signaling in the bone, and analysis of how the HBP1-BRMS1-BRMSL1 axis controls cell cycle progression genes through the SIN3A-mediated chromatin landscape.
Application Deadline: Open Until Filled
19. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Applications are sought for a Post-Doctoral or Research Associate position in the Department of Cancer Prevention and Control at Roswell Park Comprehensive Cancer Center. The candidate will take part in NIH-funded projects on HPV infection and related diseases in high-risk populations. Projects include a large HPV vaccine surveillance study of inner-city minority youth, and a prospective study of oral HPV and the microbiome in HIV+ individuals. The candidate is expected to analyze data, publish papers, assist with preparing grants, and help supervise graduate and undergraduate students. The position will be for a period of 2 years, with possibility of extension, and comes with a competitive salary and attractive benefits.
Application Deadline: Open Until Filled
20. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Our laboratory studies and develops adoptive T cell therapies targeting solid tumors. The postdoctoral scientist will focus on developing genetically engineered T cells starting from the molecular cloning phase of cell therapy development, and then advancing to preclinical in vitro work and clinically relevant mouse models. A strong background in immunology and molecular biology will allow the successful applicant to be creative within the lab, enhancing T cell function and tumor targeting for optimal patient translation and high impact publication. The postdoctoral scientists will work within the Center for Immunotherapy, which holds multiple institutional level grants and houses multiple investigators – including immunologists, molecular biologists, and computational biologists – dedicated to developing immunetherapies. Strong support for career development and academic and educational activities are included.
Application Deadline: Open Until Filled
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21. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Under the supervision of Rodney Haring, PhD, Director for the Roswell Park Center for Indigenous Cancer Research and in collaboration with the Center’s Community Advisory Board, regional, national, and international Indigenous partners, the postdoc will receive mentored support for creating and implementing research projects, analyzing data, writing manuscripts and submitting for publication. The postdoc will also assist with coordinating existing partnerships with the Center’s outreach team, Roswell’s Community Outreach and Engagement, Roswell’s shared resources and along with the support for building new partnerships toward community-based research and wet/dry lab investigation dedicated to services and innovation.
Application Deadline: Open Until Filled
22. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Postdoctoral position is open for highly motivated candidates in the laboratory of Dr. Subhamoy Dasgupta at the Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, NY- a National Cancer Institute (NCI) designated comprehensive cancer center. The Dasgupta lab focuses on discovering novel tumor metabolic adaptations, and investigates associated biological mechanisms such as transcriptional regulation, nuclear receptor and steroid hormone action, nutrient signaling, mitochondrial biology, epigenetics, and tumor immunology in the progression of cancer metastasis (Sawant Dessai A, et al, Under Review, 2020; Dasgupta S, et al, Nature, 556, 249–254, 2018; Dasgupta S, et al, Journal of Clinical Investigation, 125(3):1174-88, 2015).
Application Deadline: Open Until Filled
23. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Our laboratory is broadly interested in transcriptional regulation and cell-fate determination in cancer cell biology and treatment. We are seeking a highly motivated and skilled candidate to work on a novel family of transcriptional and cell-fate regulators in cancer cell biology and treatment response, and stem cell biology. The candidate will be surrounded by a stimulating research environment, cutting-edge technology, and daily interactions with colleagues in other labs. The training environment will be one where regular discussion of new ideas, and freedom to explore new avenues of investigation, will be encouraged.
Application Deadline: Open Until Filled
24. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A research group at Roswell Park Comprehensive Cancer Center Department of Cancer Prevention and Control (Buffalo, NY) is looking for a postdoctoral research fellow, who is interested in academic research of cancer epidemiology, genomics, and cancer health disparities. The group is dedicated to cutting-edge population-based research to understand the biological underpinnings of cancer racial/ethnic disparities, with multiple active federal and private foundation funded research projects focusing on genomic, molecular, and cellular mechanisms underlying cancer health disparities in several large and unique racial/ethnic minority populations, as well as on cancer outcome and survivorship. The group has been generating a large amount of genomic and molecular datasets from these large patient populations that provides numerous training and research opportunities for manuscript writing, as well as the development of independent research proposals.
Application Deadline: Open Until Filled
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25. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A postdoc position is immediately available to study the biology of acute leukemia and perform preclinical evaluation of promising therapeutic approaches for acute leukemia. Candidates should be highly motivated and able to work independently in designing, performing, and analyzing experiments. Experience in data presentation (oral/poster) and writing skills are highly desired. Proficiency in laboratory skills includes flow cytometry, fluorescent microscopy, in vitro proliferation/cytotoxicity assays, western blots, RNA/DNA extraction and other molecular biology techniques are required. Candidates with prior experience working on tumor mouse models are preferred (but not required).
Application Deadline: Open Until Filled
26. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The project will study the role of the HBP1-BRMS1-BRMSL1 axis in controlling breast cancer dormancy in the bone microenvironment. The project involves an in vitro 3D culture model that recapitulates bone endosteal or vascular niche microenvironments. As well, the project involves in vivo spontaneous and experimental breast cancer bone colonization models (orthotopic and intracardiac injections), in vivo monitoring of metastatic growth and signaling in the bone, and analysis of how the HBP1-BRMS1-BRMSL1 axis controls cell cycle progression genes through the SIN3A-mediated chromatin landscape.
Application Deadline: Open Until Filled
