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24 Postdoctoral Fellowships at Scripps Research Institute, California

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Are you holding PhD degree and looking for Postdoctoral Fellowships? Scripps Research Institute, California invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.

1. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are seeking a highly motivated Postdoctoral Associate. The Droujinine Lab develops novel methods to identify and characterize novel secreted factors that coordinate organ and organism functions in homeostasis and disease in mammalian systems. To that end, we established an in vivo global proteomic platform to investigate secreted protein trafficking between organs in mice. Ideal candidate will lead their own project, and perform mammalian cell culture, in vivo mouse experiments, quantitative TMT mass spectrometry proteomics, metabolomics, western blot, pulldowns, DNA cloning, immunostaining, confocal microscopy, high throughput screens, and bioinformatic data analysis. Significant emphasis is placed on the professional development of the Postdoctoral Associate.

Application Deadline: Open Until Filled

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2. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Dr. Lotz lab at Scripps Research is looking for a highly motivated individual with strong background and technical expertise in cell and molecular biology and bioinformatics for our program on transcription factors in joint biology and arthritis pathogenesis. In a newly funded program about mechanisms of joint tissue destruction and joint pain, we are using Omics technologies (RNA-seq, single cell-RNA-seq, ChIP-seq, epigenetic analyses, spatial transcriptomics) to identify dysregulated transcription factors and test candidate genes in vitro and using mutant mouse strains. Genes that are identified to be essential regulators of homeostatic processes or to promote arthritis pathogenesis are tested in viral gene delivery approaches and used in drug screening assays.

Application Deadline: Open Until Filled

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3. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Jiang Zhu’s laboratory at Scripps Research is looking for a highly motivated postdoctoral researcher with a background in B cell immunology to contribute to rational vaccine development for diverse viral pathogens including SARS-CoV-2, HIV-1, influenza, and Ebola. The person filling this position is expected to play an important intellectual, technical, and scientific role in projects including, but not limited to, single-cell sorting, immunoprofiling, and next generation sequencing (NGS) of B cells elicited by experimental vaccines being developed in our laboratory.

Application Deadline: Open Until Filled

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4. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Shannon Miller’s laboratory at Scripps Research is currently seeking talented Postdoctoral Associate candidates. The Miller Lab uses directed evolution and engineering to develop novel technologies for biomolecule delivery, with a focus on improving in vivo delivery of genome editing agents. Areas of exploration encompass non-viral and viral approaches, including engineering viral payload (RNA/DNA/protein), increasing viral packaging limit, exploring natural diversity for new evolutionary starting points, and improving in vivo biomolecule stability. The candidate would lead efforts towards the creation of bacterial circuits for the improved activity of viral packaging proteins, development of technologies that enable packaging of non-canonical materials, and development and implementation of assays to evaluate the properties of the resulting biomolecules and vectors.

Application Deadline: Open Until Filled

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5. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Hepatocellular carcinoma (HCC) is a major cause of cancer death worldwide, accounting for over half a million deaths per year. Multiple non-viral factors have also been implicated in the development of HCC. The development of non-alcoholic steatohepatitis (NASH) represents high-risk factors for HCC. Our lab demonstrated that cyclophilin inhibitors alone or in combination with new attractive drugs suppress the development of liver fibrosis and HCC in mouse models. However, their mechanisms of action are totally unknown.

Application Deadline: Open Until Filled

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6. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Department of Chemistry at Scripps Research has open Postdoctoral Associate positions in the new lab of Dr. Yuzhong Liu. Successful candidates should be self-motivated, and detail oriented with a strong background in molecular biology, chemistry, or chemical/biomolecular engineering. Scientific competence include independent research capabilities, generating publications, and contributing to grant writing. It is important that the applicant has clear oral and written communication skills and would work with and mentor students.

Application Deadline: Open Until Filled

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7. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

As a Postdoctoral Associate, you will play a key role in processing terabytes of data from our partners, developing new AI algorithms and presenting the results in top academic journals. You will collaborate with AI experts and clinical professionals, leading the development of new solutions in Digital Medicine.

Application Deadline: Open Until Filled

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8. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Jiang Zhu’s laboratory at Scripps Research is looking for a highly motivated postdoctoral researcher with a background in virology to contribute to rational vaccine development for diverse viral pathogens including SARS-CoV-2, HIV-1, influenza, and Ebola. The person filling this position is expected to play an important intellectual, technical, and scientific role in projects including, but not limited to, pseudovirus assays to measure neutralizing antibody responses elicited by experimental vaccines being developed in our laboratory.

Application Deadline: Open Until Filled

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9. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Scripps Research is seeking a motivated postdoctoral associate to work in the area of neural circuits and neuroendocrine biology of metabolism. It is now well-established that communication between the brain and the gut, the so-called gut-brain axis, regulates important aspects of behavior and metabolism in many species. However, the salient mechanisms and molecular features of gut-brain communication remain mysterious. In our lab, we utilize C. elegans as a model system for our discovery studies of gut-brain communication, in which we utilize cutting-edge technologies to measure dynamic neural and metabolic activity in living animals. Such cell-based readouts are coupled with changes in behavior and metabolism, to uncover novel pathways all the way from molecules to whole-animal biology.

Application Deadline: Open Until Filled

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10. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Associate position is available in the Mendoza Lab at Scripps Research to investigate cellular and molecular mechanisms of neuroimmune interactions. We are seeking a postdoc with a strong background in molecular biology, imaging, and murine models. The postdoc will be responsible for projects involving genetic mouse models, single cell transcriptomics and validation of molecular mechanisms in sensory neurons for sensing of distinct immune challenges, and how those affect inflammation.

Application Deadline: Open Until Filled

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11. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The structural genomics cell biology laboratory of Dr. William E. Balch in the Department of Molecular Medicine at Scripps Research has an opening for a candidate with strong computational skills. The candidate will apply machine learning to understand and treat the underlying basis of mono- and polygenic diseases impacting the protein function in response to genetic variation in the human population. Successful candidates will contribute to the development and application of AI to assess the impact of genetic diversity unique to each individual for different gene targets that challenge human health affecting both host and host-pathogen (virus) relationships. Candidates with computational experience in exploring the impact of genetic variation on protein fold structure and response to modulating therapeutics using large datasets are of high interest.

Application Deadline: Open Until Filled

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12. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Postdoctoral Associate will determine protein dynamics in genetically defined brain cell types in animal models of Alzheimer’s Disease using bio-orthogonal non-canonical amino acid tagging (BONCAT) of newly-synthesized proteins and quantitative mass spectrometry, and conduct studies examining cellular and molecular mechanisms contributing to synaptic and neuronal function and plasticity. The candidate will be actively involved in optimizing experimental design, data analysis, data interpretation and preparing manuscripts and presentations.

Application Deadline: Open Until Filled

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13. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Associate position is available in the Lotz laboratory at Scripps Research, La Jolla, California. The Lotz lab focuses on the discovery of molecular and cellular mechanisms that are dysfunctional in spine and joint diseases and other musculoskeletal conditions during early stages of pathogenesis to create a foundation for therapeutic interventions to prevent disease onset and slow progression.

Application Deadline: Open Until Filled

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14. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Briney Lab is seeking a Postdoctoral Associate to join us in the Department of Immunology and Microbiology at Scripps Research. We use a combination of advanced single cell multi-omics techniques and sophisticated computational tools to deeply explore the antibody response to emerging infectious diseases. We are looking for a highly motivated individual who will contribute to antibody discovery projects against a variety of viral targets, including Lassa, Ebola, HIV, SARS-CoV-2, influenza and others. The antibodies we discover have potential use as therapeutics or as templates for rational vaccine development.

Application Deadline: Open Until Filled

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15. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Lippi lab at Scripps Research seeks a Postdoctoral Associate as part of a growing team of investigators studying how a class of non-coding RNAs, called microRNAs, instructs brain development. We have developed molecular tools to map and manipulate microRNA-target interactions in specific cell types of the brain. We are now recruiting researchers that want to apply these tools to understand microRNAs mechanisms establishing neuronal identity and wiring neural circuits. Collectively, our work spans multiple disciplines, including tool development, molecular, cellular and system neuroscience.

Application Deadline: Open Until Filled

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16. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Ahmed H. Badran’s laboratory at Scripps Research seeks to hire 3-4 highly motivated Postdoctoral Associates to start in 2021-2022. The Badran Lab aims to address technical shortcomings in conserved cellular processes through innovative synthetic/chemical biology, directed evolution, genome editing and bioengineering approaches. Specifically, we aspire to develop tools for accelerating the evolution of macromolecular biosynthetic machinery and whole organisms.

Application Deadline: Open Until Filled

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17. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Multiple fully funded positions for post-doctoral fellows are currently available in the Erb laboratory (Department of Chemistry, The Scripps Research Institute, La Jolla, CA). Our chemical biology group uses discovery chemistry, CRISPR/Cas9-based functional genetic screens, and advanced transcriptional genomics approaches to discover and study drug-like small molecules that therapeutically modulate chromatin regulation and mRNA transcription. We are seeking to hire multiple post-doctoral fellows to lead projects in ligand discovery, chromatin regulation, and cancer biology. Successful candidates will have laboratory experience in biology, chemistry, or computer science and be committed to working in a collaborative, multidisciplinary group with the goal of advancing new chemical tools, genetic insights, and therapeutic hypotheses.

Application Deadline: Open Until Filled

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18. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

An NIH-funded Postdoctoral Associate position is available for a motivated individual to join the lab of Professor Pietro Paolo Sanna at The Scripps Research Institute to study the neurobiology of substance abuse and neuroAIDS. This dynamic multidisciplinary research team uses in vivo, biochemical and genomic strategies including gene expression anlaysis by single cell RNA-Sequencing, electrophysiology and the establishment of neuronal cell types from induced pluripotent stem cells and fibroblasts.

Application Deadline: Open Until Filled

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19. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Associate position is available for a motivated individual to join a dynamic multidisciplinary research team at The Scripps Research Institute to study neuroimmunological and neuroinflammatory aspects of alcohol abuse and neuroAIDS with in vivo, biochemical and genomic strategies including gene expression analysis by single cell RNA-Sequencing.

Application Deadline: Open Until Filled

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20. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are looking for talented, highly motivated post-doctoral candidates with a strong interest in basic virology and immunology. The successful candidate will join a team investigating mechanisms of virus-host interactions, with a focus on identifying cellular antiviral responses and molecular signatures linked to severe disease. These studies will utilize systems biology, including large-scale technologies (CRISPR/RNAi, proteomics/ chemoproteomics, chemical biology, NextGen Sequencing, etc.), as well as fundamental virology and more traditional cellular/molecular biology and biochemistry-based approaches.

Application Deadline: Open Until Filled

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21. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Associate position is immediately available in the Immunology and Microbiology Department in the laboratory of Dr. Sumit K. Chanda as part of a multi-disciplinary program focused on using a systems-level understanding of innate immunity, immunology, and virus-host interactions. The successful candidate will join a team investigating mechanisms of virus-host interactions, with a focus on utilizing chemical biology and chemoproteomics tools to identify novel host-pathogen interactions that underlie viral infection and to develop novel therapeutic strategies to facilitate pandemic preparedness. Studies will focus on RNA viruses of pandemic potential, including influenza virus, coronavirus, flaviviruses, and filoviruses.

Application Deadline: Open Until Filled

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22. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Peng lab in the Department of Neuroscience at Scripps Research in La Jolla, California has an available Postdoctoral Associate position for an accomplished researcher in computational genomics, statistical genetics, behavior genetics, and/or computational biology to deepen their knowledge in the context of the emerging area of addiction and behavioral genomics.

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23. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The lab is developing new, general approaches to control the site and timing of enzyme activity. Enzymes have great potential as therapeutic and diagnostic agents due to their high specificity and catalytic activity, but the ability to better control the timing and location of enzyme function would enable the use of a wider variety of enzymes for therapeutic purposes. Our approach for enzyme programming relies on attaching an enzyme to its small-molecule inhibitor through an allosteric DNA tether. Upon interaction of the DNA tether with its complement strand, the ensuing conformational change activates the enzyme by dislodging the inhibitor from its active site.

Application Deadline: Open Until Filled

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24. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Associate position is available in Dr. Lisa Racki’s Lab at the Scripps Research Institute in La Jolla, CA (rackilab.org) for a highly motivated scientist interested in bacterial chromatin and the role of chromatin in regulating bacterial phages. Specifically, this project will use phage and phage-derived tools to characterize the organization, structure, and dynamics of bacterial chromatin in the opportunistic human pathogen Pseudomonas aeruginosa. This project uses an integrative approach to study bacterial chromatin structure at multiple scales, from in vitro biochemistry, to quantitative single cell timelapse imaging using microfluidics, to macroscopic studies of biofilm communities.

Application Deadline: Open Until Filled

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