Are you holding PhD degree and looking for Postdoctoral Fellowships? St. Jude Children’s Research Hospital, Tennessee invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.
1. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Fischer lab at St. Jude is recruiting a Postdoc for an NIH-funded project that exploits the role of water networks in protein binding sites. We are looking for applicants with a strong training in the gene-to-structure pipeline and/or in structural bioinformatics, and a keen interest or ideally experience in ligand discovery.
Application Deadline: Open Until Filled
2. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The laboratory of Dr. Peijun Ma in the Department of Pharmacy and Pharmaceutical Sciences in St. Jude Children’s Research Hospital, Memphis, TN is a new research group that uses single-cell genomics and transcriptomics to study antibiotic resistance and persistence in bacterial pathogens. Past work has focused on developing bacterial single-cell RNA sequencing technology (Ma et al., Cell, 2023) and understanding the evolution of antibiotic resistance in gram-negative bacterial pathogens (Ma et al., eLife, 2021).
Application Deadline: Open Until Filled
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3. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A postdoctoral position is available in the Chang lab in the Department of Cell & Molecular Biology at St. Jude Children’s Research Hospital. We are looking for highly talented, self-motivated individuals passionate about how organelles communicate. In particular, the candidate will interrogate the fundamental questions of ER-to-Golgi trafficking via cutting-edge light and electron microscopy, genome-editing, biochemistry and in vitro reconstitution approaches.
Application Deadline: Open Until Filled
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4. Postdoctoral Position
Summary of Postdoctoral Fellowship:
We are seeking a highly motivated Postdoc Research Associate to join Dr. Ji Sun’s lab at St. Jude Children’s Research Hospital. Successful candidates will lead research projects focusing on disease-causing protein complexes, using an integrative approach combining structural, biochemical, and cell biology methods (Myasnikov A et al., Cell 2021; Zhu H et al., Biorxiv 2022, Jiang M et al., Cell Research, 2023).
Application Deadline: Open Until Filled
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5. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A postdoctoral research associate position is immediately available in the laboratory of Dr. Xiang Chen in the department of Computational Biology to develop and apply innovative machine learning/statistical learning approaches to understand interactions between genetic alterations and epigenetic deregulations and to discover potential biomarkers for predicting drug responses in pediatric cancers. One of the premier pediatric research institutions in the world, St. Jude Children’s Research Hospital provides exceptional resources, a collaborative environment, and access to extensive, unique cancer genomics datasets from large-scale research initiatives.
Application Deadline: Open Until Filled
6. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Several postdoctoral researcher positions are immediately available in the laboratory of Dr. Doug Green in the Department of Immunology in St. Jude Children’s Research Hospital. Research in Dr. Green’s laboratory focuses on the process of active cell death and cell survival, extending from the role of cell death in cancer regulation and immune responses in the whole organism to the fundamental molecular events directing the death and survival of the cell. Preference will be given to individuals with an interest in cell death mechanisms, or the metabolism of activated T lymphocytes.
Application Deadline: Open Until Filled
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7. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A postdoctoral position is available at St. Jude Children’s Research Hospital for an outstanding and highly motivated candidate to investigate the proteins of the innate immune system biochemically and structurally. We are particularly interested in assessing proteins involved in innate immune responses and cell death (NLRs, caspases, inflammasomes, and inflammatory cell death, PANoptosis).
Application Deadline: Open Until Filled
8. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Obeng Laboratory is seeking creative and highly motivated candidates for a fully supported postdoctoral fellowship studying the pathogenesis of myeloid malignancies. The major interests of the lab are determining how acquired mutations in hematopoietic stem cells lead to the development of clonal hematopoiesis, myelodysplastic syndrome, and leukemia, in addition to identifying and studying novel treatments that selectively target malignant clones.
Application Deadline: Open Until Filled
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9. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Postdoctoral positions are available in the laboratory of Dr. Stacey Ogden at St. Jude Children’s Research Hospital to research mechanisms of Sonic Hedgehog signaling during development. We use genetic model systems and cutting-edge imaging technologies to interrogate these fascinating cell biological questions. Prior experience with mouse models and confocal microscopy is preferred, but not required.
Application Deadline: Open Until Filled
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10. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Postdoctoral positions are available in the laboratory of Dr. Stacey Ogden at St. Jude Children’s Research Hospital to research mechanisms of Sonic Hedgehog signaling during development. We use genetic model systems and cutting-edge imaging technologies to interrogate these fascinating cell biological questions. Prior experience with mouse models and confocal microscopy is preferred, but not required.
Application Deadline: Open Until Filled
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11. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Obeng Laboratory is seeking creative and highly motivated candidates for a fully supported postdoctoral fellowship studying the pathogenesis of myeloid malignancies. The major interests of the lab are determining how acquired mutations in hematopoietic stem cells lead to the development of clonal hematopoiesis, myelodysplastic syndrome, and leukemia, in addition to identifying and studying novel treatments that selectively target malignant clones.
Application Deadline: Open Until Filled
12. Postdoctoral Position
Summary of Postdoctoral Fellowship:
HSCs represent the most therapeutically exploited adult stem cell compartment, used routinely to treat leukemia and hematologic disease via HSC transplantation. Indeed, HSC transplantation represents the only cure for Sickle Cell Disease, including autologous HSC transplantation combined with gene therapy. Here, our major goals are to better understand how elevated hematopoietic demand and chronic inflammation associated with Sickle Cell Disease perturbs the phenotype and function of HSCs. We employ both genetic mammalian model systems and primary patient samples to pursue these aims.
Application Deadline: Open Until Filled
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13. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Tsai Laboratory is seeking dynamic and creative candidates for a fully supported postdoctoral fellowship on genome editing technologies for therapeutic treatment of genetic disorders. CRISPR genome editors, adapted from bacterial adaptive immune systems, are transforming both basic biological research and genomic medicine. At St. Jude, we are working toward advancing these technologies towards patient treatments for sickle cell disease and bone marrow failure disorders.
Application Deadline: Open Until Filled
14. Postdoctoral Position
Summary of Postdoctoral Fellowship:
An exciting career opportunity is available for a postdoctoral researcher in the laboratory of Dr. Andrew Davidoff to explore novel gene therapy and small molecule techniques in the treatment of solid tumors. The Davidoff lab seeks an inventive researcher to develop novel gene therapy vectors and test them in our translational models of neuroblastoma and liver cancers. The ideal candidate will have experience with models of solid tumors and/or AAV-based gene therapy vectors, to seek innovative cures for rare pediatric cancers.
Application Deadline: Open Until Filled
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15. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A wet-lab postdoctoral position is available immediately in the Northcott Lab (Department of Developmental Neurobiology) to join a highly collaborative team studying the developmental and molecular basis of the childhood brain tumor medulloblastoma. The Northcott Lab has established an internationally renowned track record in pediatric neuro-oncology, substantiated by numerous impactful publications in Nature, Cancer Cell, Lancet Oncology, and Journal of Clinical Oncology. Leveraging our exquisite access to patient material linked to large clinical trial cohorts, we are applying a combination of innovative, multi-omic approaches to discover new biological, mechanistic, and clinical insights responsible for medulloblastoma initiation, progression, and relapse.
Application Deadline: Open Until Filled
16. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Chen Lab studies: i) Chemical modulation of transcription; ii) Signal crosstalk among transcription factors; and iii) Selective inhibition of highly homologous enzymes. We take a hypothesis-driven and technology-enabled multidisciplinary approach to develop chemical probes and investigate biological mechanisms. Particularly we use the promiscuous xenobiotic nuclear receptors (PXR and CAR) as models to investigate the transcription networks that regulate therapeutic responses. PXR and CAR regulate the detoxification system (e.g., by transcriptionally controlling CYP3A4 and CYP3A5—drug-metabolizing enzymes that metabolize more than 50% of clinical drugs), the dysregulation of which contributes to drug toxicity and drug resistance.
Application Deadline: Open Until Filled
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17. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Several postdoctoral positions are available in the laboratory of Dr. Victor J. Torres in the new Department of Host-Microbe Interactions at St. Jude Children’s Research Hospital. The Torres lab is interested in dissecting the complex interactions between pathogenic bacteria and the mammalian host. Currently, the lab is focusing on antibiotic resistant (AMR) bacteria, which have been recognized by the World Health Organization as a serious threat to human health.
We take advantage of multidisciplinary approaches and combine techniques from bacteriology, genetics, molecular biology, biochemistry, structural biology, cellular biology, and immunology with primary tissue culture models and a variety of murine models of infection, to address our favorite questions. Our ultimate goal is to understand the basic principles of bacterial pathogenesis as well as to develop a platform for the discovery of targets that could be exploited for the generation of much-needed therapies.
Application Deadline: Open Until Filled
18. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Advance hope, medical science, statistical science, and your career as a postdoctoral fellow in the Department of Biostatistics at St. Jude Children’s Research Hospital. A Ph.D. in statistics, biostatistics, computer science, or closely related field is required. Appointment is for two years. Applicants must have a strong computational background and demonstrate excellent written and verbal communication skills.
Application Deadline: Open Until Filled
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19. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Gottschalk Laboratory is seeking a highly motivated and creative candidate for a fully supported postdoctoral fellowship to develop immune-based therapies. Specifically, the research is aimed to develop T-cell-based therapies for pediatric solid tumors. Studies are focused on using genetic engineering approaches to not only render immune cells cancer specific, but also improve their effector function.
Genetically modified immune cells will be studied in preclinical models with special emphasis on how adoptively transferred cells interact with tumor cells, the tumor microenvironment, and resident immune cells. Ultimate goal of these studies is to translate these approaches into early Phase clinical testing.
Application Deadline: Open Until Filled
20. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Advance hope, medical science, statistical science, and your career as a postdoctoral fellow in the Department of Biostatistics at St. Jude Children’s Research Hospital. For eight consecutive years, St. Jude has ranked among the top places to work in the U.S. by Forbes Magazine. Salary and benefits are competitive. Send cover letter, CV, and three recommendation letters to Dr. Tomi Mori via e-mail at tomi.mori@stjude.org.
Application Deadline: Open Until Filled
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21. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The project aims to understand how KDMs coopts oncogenic transcription factors to drive tumorigenesis and metastasis, and use novel KDM inhibitors to target metastasis and disease relapse. To this end, we apply interdisciplinary strategies by integrating genetic approaches (transgenic mouse models and conditional knockout) with cutting-edge systems (Cut&Tag, HiChIP, ATAC-seq, scRNA-seq, spatial transcriptomics), and functional genomics tools (Genome-wide and focused CRISPR libraries, CRISPR knockin, CRIPSRi and CRISPRa) as well as proteomics and metabolomics.
Application Deadline: Open Until Filled
