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21 Postdoctoral Fellowships at Roswell Park Cancer Center, New York

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Roswell Park Cancer Center, New York, USA invites multiple online application for Postdoctoral Fellowships (salary: $54,840 – $65,000) in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.

1. Postdoctoral Position in Molecular and Genetic Cancer Epidemiology

Summary of Postdoctoral Fellowship:

A research group at Roswell Park Comprehensive Cancer Center Department of Cancer Prevention and Control (Buffalo, NY) is looking for a postdoctoral research fellow, who is interested in academic research of cancer epidemiology, genomics, and cancer health disparities. The group is dedicated to cutting-edge population-based research to understand the biological underpinnings of cancer racial/ethnic disparities, with multiple active federal and private foundation funded research projects focusing on genomic, molecular, and cellular mechanisms underlying cancer health disparities in several large and unique racial/ethnic minority populations, as well as on cancer outcome and survivorship.

Application Deadline: Open Until Filled

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2. Postdoctoral Position in Myeloma

Summary of Postdoctoral Fellowship:

The Multiple Myeloma/Amyloidosis Service of the Department of Medicine is seeking a full-time Postdoctoral Fellow in the laboratory of Dr. Jens Hillengass. The Hillengass lab in collaboration with Drs. Philip McCarthy and Hemn Mohammadpour focuses on the tumor microenvironment of multiple myeloma and spatial heterogeneity of immune cells and their function in monoclonal plasma cell disorders. Using modern genomic DNA and RNA sequencing approaches, murine models as well as immunological analyses we have shown that the tumor microenvironment changes in osteolytic lesions compared to the random bone marrow and healthy bone marrow.

Application Deadline: Open Until Filled

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3. Postdoctoral Position in Leukemia

Summary of Postdoctoral Fellowship:

A postdoc position is immediately available to study the biology of acute leukemia and perform preclinical evaluation of promising therapeutic approaches for acute leukemia. Candidates should be highly motivated and able to work independently in designing, performing, and analyzing experiments. Experience in data presentation (oral/poster) and writing skills are highly desired. Proficiency in laboratory skills includes flow cytometry, fluorescent microscopy, in vitro proliferation/cytotoxicity assays, western blots, RNA/DNA extraction and other molecular biology techniques are required. Candidates with prior experience working on tumor mouse models are preferred (but not required).

Application Deadline: Open Until Filled

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4. Postdoctoral Position in Cancer Genetics & Genomics

Summary of Postdoctoral Fellowship:

The project will study the role of the HBP1-BRMS1-BRMSL1 axis in controlling breast cancer dormancy in the bone microenvironment. The project involves an in vitro 3D culture model that recapitulates bone endosteal or vascular niche microenvironments. As well, the project involves in vivo spontaneous and experimental breast cancer bone colonization models (orthotopic and intracardiac injections), in vivo monitoring of metastatic growth and signaling in the bone, and analysis of how the HBP1-BRMS1-BRMSL1 axis controls cell cycle progression genes through the SIN3A-mediated chromatin landscape.

Application Deadline: Open Until Filled

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5. Postdoctoral Position in Cancer Immunotherapy and GYN Cancer

Summary of Postdoctoral Fellowship:

A Postdoctoral position is open for a highly motivated candidate in the laboratory of Dr. AJ Robert McGray in the Department of Immunology. The project will focus on developing and optimizing strategies for the delivery of immune cell engagers (e.g. BiTEs) targeting the tumor and/or tumor stroma as potent cancer immunotherapies. The selected individual will use both in vitro systems and in vivo mouse models to develop, validate, and therapeutically test immune cell engagers. While a primary focus of this research will be to develop therapies that can be translated clinically to treat ovarian cancer, projects are anticipated to be broadly applicable to other tumor indications and will involve parallel studies in other disease areas.

Application Deadline: Open Until Filled

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6. Postdoctoral Position in Immunotherapy

Summary of Postdoctoral Fellowship:

The laboratory of Dr. Renier Brentjens in the Department of Medicine is looking for a postdoctoral candidate to work on a research project aiming to generate novel chimeric antigen receptor (CAR) T cells specifically targeted to antigens for the treatment of cancer. The specific research project involves usage and identification of antigens for targeted cell therapies, CAR design, and experimental models to validate antitumor capacity. The selected individual will perform studies in human in vitro models (and potentially mouse in vitro and in vivo models) to validate and enhance ability of CAR T cells to be used as effective cell therapy.

Application Deadline: Open Until Filled

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7. Postdoctoral Position in Pediatric Oncology

Summary of Postdoctoral Fellowship:

The Department of Pediatric Oncology is seeking a full time Postdoctoral Fellow in the laboratory of Dr. Nataliya Buxbaum. The Buxbaum lab focuses on immunometabolism as it relates to hematopoietic stem cell transplantation (HSCT) and cellular immunotherapies. Our bench-to-bedside laboratory and clinical investigations are centered on graft-versus-host disease (GvHD) with a goal of developing new imaging and therapeutic modalities for this condition (Assmann, J.C. et al. Blood, 2021; Mhandire, K. et al. Metabolites, 2021; Buxbaum, NP, et al. Journal of Clinical Investigation Insight, 2017).

Application Deadline: Open Until Filled

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8. Postdoctoral Position in prostate cancer lineage plasticity

Summary of Postdoctoral Fellowship:

The Goodrich lab at Roswell Park Comprehensive Cancer Center is looking for a highly motivated postdoctoral fellow to study prostate cancer lineage plasticity (see Ku et al. Science 2017, Mu et al. Science 2017, Pearson et al. Cancer Cell, 2021). The postdoc will work with a dynamic team of clinicians and scientists to perform both pre-clinical experiments and clinical trial correlative studies aimed at both understanding mechanisms underlying prostate cancer lineage plasticity and targeting them for therapeutic benefit.

Application Deadline: Open Until Filled

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9. Postdoctoral Position in Medicine

Summary of Postdoctoral Fellowship:

The Sung Lab at Roswell Park Comprehensive Cancer Center is seeking a postdoctoral fellow to study therapeutic resistance to targeted therapy in acute myeloid leukemia. Dr. Sung has a joint appointment in the Department of Medicine (Leukemia Service) and the Department of Pharmacology & Therapeutics. The overall goal of the lab is to develop novel therapeutic strategies for translation to early phase clinical studies in AML. Our current focus is on FLT3 inhibition and its role in modulating the epigenetic state and myeloid differentiation in AML (supported by NCI K08).

Application Deadline: Open Until Filled

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10. Postdoctoral Position in oncogenic action of Agrin

Summary of Postdoctoral Fellowship:

A postdoc position is available immediately, in Dr. Sayan Chakraborty’s laboratory to study an exciting project that investigates the in-depth molecular and biochemical mechanisms of the oncogenic action of Agrin. The Chakraborty lab is commencing at Roswell Park in the summer of 2022. Previous studies from our group have shown that Agrin acts as a master regulator of mechanotransduction via YAP/TAZ activation and ‘outside-in communications’ via engagement of integrin-focal adhesion complexes in cancer cells. Using liver cancer models, we have recently observed that Agrin shapes up the mechanical landscape of the tumor microenvironment (TME) and modulates tumor angiogenesis by stabilizing VEGFR2.

Application Deadline: Open Until Filled

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11. Postdoctoral Position in Urology

Summary of Postdoctoral Fellowship:

We are seeking an enthusiastic and talented candidate with a Ph.D. in neuroscience, engineering, computer science, cognitive psychology, the biomedical sciences, or a field related to neuroscience to join the Mind Maps Project at the Applied Technology Laboratory for Advanced Surgery (ATLAS) Program at Roswell Park Comprehensive Cancer Center in Buffalo, NY. We are planning to start a new artificial intelligence lab at Roswell Park and this candidate will be actively involved in this initiative.

Application Deadline: Open Until Filled

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12. Postdoctoral Position in Urology (Bladder Cancer Program)

Summary of Postdoctoral Fellowship:

We are seeking an enthusiastic and talented candidate with a Ph.D. in cancer biology, genetics, molecular biology, experimental therapeutics, bioinformatics or related field. Perform a variety of routine and specialized lab tests and experimental procedures. Have access to patient database, tissue specimen, cell culture, patient-derived xenograft, next-generation sequencing and genetic mouse model.

Application Deadline: Open Until Filled

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13. Postdoctoral Position in Urology

Summary of Postdoctoral Fellowship:

Our team is interested in translational research that uses physiological data to develop prediction models to improve cancer patients’ quality of life. We are seeking a highly motivated candidate to Contribute to data analysis and development of prediction models using one of these platforms: Python, Matlab, or R. Work closely with the team to develop peer-reviewed journal and conference drafts

Application Deadline: Open Until Filled

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14. Postdoctoral Position in Cancer Immunology

Summary of Postdoctoral Fellowship:

The laboratory of Dr. Marco Davila in the Department of Medicine is looking for a postdoctoral candidate to work on a research project aiming to generate novel chimeric antigen receptor (CAR) T cells specifically targeted to antigens for the treatment of cancer. The specific research project involves the usage and identification of antigens for targeted cell therapies, CAR design, and experimental models to validate antitumor capacity. The selected individual will perform studies using in vitro models to validate and enhance the ability of CAR T cells to be used as effective cell therapy.

Application Deadline: Open Until Filled

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15. Postdoctoral Position in Molecular and Cellular Biology

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow position is available in the laboratory of Dr. Ethan V. Abel in the Department of Molecular and Cellular Biology. Position offers independence as well as important collaborative opportunities. Research will focus on the functional characterization of transcriptional/epigenetic regulators and signaling proteins in pancreatic cancer, and how these cellular components regulate drug resistance, cancer stem cells, metastasis, and metabolism to drive the disease. The laboratory’s research places equal emphasis on basic, mechanistic discovery and translational/preclinical research.

Application Deadline: Open Until Filled

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16. Postdoctoral Position in pathogenesis of ovarian cancer

Summary of Postdoctoral Fellowship:

A postdoctoral position is immediately available in the laboratory of Karen McLean, MD, PhD, in the Gynecology Department at Roswell Park Comprehensive Cancer Center. Dr. McLean has a joint appointment in the Department of Pharmacology & Therapeutics, with laboratory space and access to shared resources in the Center for Genetics and Pharmacology Building. The McLean laboratory studies the pathogenesis of ovarian cancer, with projects focusing on the interplay between DNA damage repair and responses to immunotherapy as well as tumor microenvironment signaling.

Application Deadline: Open Until Filled

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17. Postdoctoral Position in Tumor Immunology

Summary of Postdoctoral Fellowship:

The Department of Immunology at Roswell Park Cancer Institute invites applications for a Postdoctoral Fellow or Research Assistant position to develop a novel platform technology that opens the possibility of multifunctional products, such as an engineered oncolytic vaccinia virus that selectively infects tumor cells, to be used as a vector for targeted delivery and expression of high concentrations of therapeutic (CXCR4-A-Fc antagonist of CXCR4 receptor) molecules in metastatic tumors.

Application Deadline: Open Until Filled

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18. Postdoctoral Position in Pharmacogenetics

Summary of Postdoctoral Fellowship:

The laboratory of Dr. Andrew Goey is looking for a highly motivated and clinically oriented postdoctoral fellow to work on improving cancer treatments by pharmacogenetics. Research that will be carried out is highly translational and include genetic association studies, clinical trials, and in vitro drug metabolism experiments. The preferred candidate will have a track record of publications in the fields of pharmacogenetics and clinical pharmacology.

Application Deadline: Open Until Filled

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19. Postdoctoral Position in Molecular Epidemiology

Summary of Postdoctoral Fellowship:

A post-doctoral position in molecular epidemiology is available in the research program of Li Tang, PhD. Dr. Tang is an Associate Professor in the Department of Cancer Prevention and Control at Roswell Park Cancer Institute, Buffalo, NY. The fellow will work closely with Dr. Tang and with intramural and extramural collaborators. The research questions of interest include: 1) How do diet and genes interact to affect cancer treatment outcomes? 2) How do genetic variants contribute to racial differences in cancer characteristics and prognosis? 3) What is the role of human endogenous retrovirus in cancer development?

Application Deadline: Open Until Filled

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20. Postdoctoral Position in Cancer Genetics & Genomics

Summary of Postdoctoral Fellowship:

The project will study the role of the HBP1-BRMS1-BRMSL1 axis in controlling breast cancer dormancy in the bone microenvironment. The project involves an in vitro 3D culture model that recapitulates bone endosteal or vascular niche microenvironments. As well, the project involves in vivo spontaneous and experimental breast cancer bone colonization models (orthotopic and intracardiac injections), in vivo monitoring of metastatic growth and signaling in the bone, and analysis of how the HBP1-BRMS1-BRMSL1 axis controls cell cycle progression genes through the SIN3A-mediated chromatin landscape.

Application Deadline: Open Until Filled

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21. Postdoctoral Position in HPV infection

Summary of Postdoctoral Fellowship:

Applications are sought for a Post-Doctoral or Research Associate position in the Department of Cancer Prevention and Control at Roswell Park Comprehensive Cancer Center. The candidate will take part in NIH-funded projects on HPV infection and related diseases in high-risk populations. Projects include a large HPV vaccine surveillance study of inner-city minority youth, and a prospective study of oral HPV and the microbiome in HIV+ individuals.

Application Deadline: Open Until Filled

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