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21 Postdoctoral Fellowships at Jackson Laboratory, Maine

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Are you holding PhD degree and looking for Postdoctoral Fellowships? Jackson Laboratory, Maine invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.

1. Postdoctoral PositionĀ 

Summary of Postdoctoral Fellowship:

The Jalili lab is seeking a highly motivated and talented postdoctoral fellow to join our team. The successful candidate will have the opportunity to work on cutting-edge research projects related to establishing an in vitro host immune-microbiome culture model for disease modeling, and vaccine and therapeutic development. We implement multiple technologies, like organoid engineering, organ on a chip platforms, microfluidics and microbiology for modeling skin and intestine inflammatory, autoimmune and cancer conditions, such as dermatitis, psoriasis, inflammatory bowel disease (IBD), Crohnā€™s disease (CD), ulcerative colitis (UC), and colon cancer.

Application Deadline: Open Until Filled

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2. Postdoctoral PositionĀ 

Summary of Postdoctoral Fellowship:

A postdoctoral associate position is available in the lab of Dr. Gary Ren to study tumor microenvironment and tumor immunology in cancer therapy resistance and metastatic relapse. Using genomic and proteomic approaches, cancer patient specimen analysis and mouse models of diverse cancer types, Dr. Renā€™s lab mainly focuses on elucidating how mesenchymal lineage cells and immunoregulatory myeloid cells modulate the adaptive immune responses in treatment resistance and metastatic relapse. These studies will fully take advantage of the unique research platform at JAX–patient-derived xenograft (PDX) tumors in humanized mouse models, with the research goal to develop novel strategies targeting tumor microenvironment to improve the efficacies of conventional cancer therapies and new therapeutics such as immunotherapy.

Application Deadline: Open Until Filled

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3. Postdoctoral PositionĀ 

Summary of Postdoctoral Fellowship:

The research projects will focus on NK cell responses to malignancy using mice, humanized mice, and human specimens. The project seeks to develop NK cell-based immunotherapies to prevent or cure solid tumors. This work will be performed using genetically engineered lung cancer mouse models and in-house generated patient-derived xenograft models (lung, and pancreatic cancer).

Application Deadline: Open Until Filled

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4. Postdoctoral PositionĀ 

Summary of Postdoctoral Fellowship:

The Associate Scientist collaborates with and assists investigators or other scientists in the planning, development, and implementation of laboratory, clinical, and/or field research studies. Designs and independently executes standard research methods, protocols, and procedures. This individual will be responsible for performing a combination of proteomic sample preparation and analysis, metabolite preparation and analysis, reporting of results to investigators, and shared routine laboratory maintenance responsibilities. Meticulous attention to detail and accurate record keeping are required.

Application Deadline: Open Until Filled

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5. Postdoctoral PositionĀ 

Summary of Postdoctoral Fellowship:

The Oā€™Connell Lab at The Jackson Laboratory is seeking a Postdoctoral Associate in systems neuroscience of obesity and energy balance. We are interested in the role of gene ā€“ environment interactions in determining individual risk for obesity and related comorbidities, including age-related neurodegenerative diseases such as Alzheimerā€™s. The lab uses interdisciplinary approaches including Patch-seq for multimodal characterization of functional, morphological, and gene expression changes in single neurons. Projects may also employ in vivo Ca2+ imaging using fiber photometry, optogenetics, and chemogenetics in genetically diverse mouse models.

Application Deadline: Open Until Filled

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6. Postdoctoral PositionĀ 

Summary of Postdoctoral Fellowship:

The Stitzel Lab at The Jackson Laboratory for Genomic Medicine in Farmington, CT is recruiting a Postdoctoral Associate to join our scientific team working to identify new proteomic biomarkers of diabetes-associated stress responses in metabolic tissues (pancreas, adipose, liver, muscle). This individual will create and employ cell and mouse models to interrogate changes in protein localization, trafficking, and processing caused by insulin resistance or exposure to diabetogenic stressors using innovative proximity proteomic (e.g., BioID, TurboID) technology. Exceptional candidates can show early independence through the JAX Scholars Program.

Application Deadline: Open Until Filled

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7. Postdoctoral PositionĀ 

Summary of Postdoctoral Fellowship:

The Stitzel Lab at The Jackson Laboratory for Genomic Medicine in Farmington, CT is recruiting a Postdoctoral Associate to join our scientific team working to understand the precise genetic mechanisms controlling pancreatic islet identity and function and identify genes and response pathways that can be therapeutically targeted to prevent islet dysfunction and enhance islet resilience. We conduct innovative allelic and functional and single cell genomic analyses of primary human islets and employ high-throughput genomic techniques (e.g. CRISPR-based screens, MPRA) to (de)code the gene regulatory circuits controlling each islet cell type in human and mouse and uncover gene targets and molecular effects of human diabetes risk variants.

Application Deadline: Open Until Filled

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8. Postdoctoral PositionĀ 

Summary of Postdoctoral Fellowship:

The Agoro lab at the Jackson Laboratory for Mammalian Genetics is seeking a highly motivated postdoctoral fellow to study redox molecular mechanisms that drive aging and chronic kidney disease. The overall goal of our laboratory is to understand the aging and kidney disease progression mechanisms using a systems biology approach as well as identifying new therapeutic strategies to improve renal function. Our laboratory is specialized in using a multidisciplinary approach that integrates genomics, proteomics, and metallomics. The postdoctoral scientist will lead an exciting project that applies a broad range of cutting-edge technologies, such as CRISPR-based tools, single-cell multi-omics, and kidney disease mouse models.

Application Deadline: Open Until Filled

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9. Postdoctoral PositionĀ 

Summary of Postdoctoral Fellowship:

We are seeking a highly motivated and skilled postdoctoral researcher to join our research team in the field of human reproductive science and women’s health. The successful candidate will be working on an exciting project focused on studying endometriosis at the single cell resolution using spatial and single cell ā€˜omics, 3D cell culture assays and multiomic approaches.

Application Deadline: Open Until Filled

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10. Postdoctoral PositionĀ 

Summary of Postdoctoral Fellowship:

A postdoctoral associate position is available in the laboratory of Dr. Erik Bloss at The Jackson Laboratory in Bar Harbor, Maine, to perform basic research investigating the mechanisms by which exercise-responsive circuits may be manipulated to prevent structural and functional decline of cortical synapses during aging and in mouse models of Alzheimerā€™s disease. This work will include chemogenetic and optogenetic manipulations of neural activity in aging mice performing exercise and multiple cognitive assays as well as high resolution microscopic reconstruction of synapses on hypothalamic and cortical neurons. The Bloss Lab offers a highly collaborative environment including opportunities with other leading laboratories in this field, nationally and internationally.

Application Deadline: Open Until Filled

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11. Postdoctoral PositionĀ 

Summary of Postdoctoral Fellowship:

The West lab is relocating to The Jackson Laboratory and is seeking an independent, highly motivated PhD-level scientist to lead a collaborative research program to investigate how mitochondrial dysfunction potentiates disease-associated inflammatory responses in primary mitochondrial disorders and cardiomyopathy. The overall goals of our laboratory are to delineate how mitochondria function as central regulators of innate immune and inflammatory responses and to investigate how mitochondria-immune crosstalk contributes to disease and aging. Our laboratory pursues a multidisciplinary approach by integrating cell biology, immunology, and physiology using cutting-edge techniques including engineered mouse models, single-cell multi-omics, super-resolution imaging, and CRISPR-based cellular tools.

Application Deadline: Open Until Filled

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12. Postdoctoral PositionĀ 

Summary of Postdoctoral Fellowship:

The Jalili lab will open in July 2023 and is seeking a highly motivated and talented postdoctoral fellow to join our team. The successful candidate will have the opportunity to work on cutting-edge research projects related to studying the host immune-microbiome interface in the context of autoimmune skin diseases, infectious diseases, and aging, using state-of-the-art engineering tools. We implement different engineering technologies, particularly microneedle skin patches, to longitudinally monitor the cross-regulation of skin microbiome and immune system in the context of the inflammatory and autoimmune skin conditions.

Application Deadline: Open Until Filled

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13. Postdoctoral PositionĀ 

Summary of Postdoctoral Fellowship:

The Tarchini Lab at The Jackson Laboratory (http://tarchini-lab.org) is seeking a Postdoctoral Associate to complete a team currently composed of two postdocs, one research assistant and rotating students or shorter term trainees. The laboratory focuses on cell polarity mechanisms and their impact on the morphogenesis of sensory ā€œhairā€ cells in the mouse auditory and vestibular organs, including hearing and balance ability. We are particularly interested in discovering new protein complexes organizing and elongating the stereocilia bundle, the apical hair cell compartment capturing sound or head movements. We are also interested in understanding how these proteins respond to damage, and more generally, to ask whether the molecular machinery assembling the stereocilia bundle during development could be leveraged to regenerate these structures after injury. We are independently funded with two R01 grants from NIH.

Application Deadline: Open Until Filled

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14. Postdoctoral PositionĀ 

Summary of Postdoctoral Fellowship:

A postdoctoral associate position is available in the laboratory of Dr. Jennifer Trowbridge at The Jackson Laboratory in Bar Harbor, Maine, to perform basic and translational research investigating why and how blood cancers develop from pre-existing clonal hematopoiesis (CHIP/ARCH). The Trowbridge Lab offers a teamwork environment including collaborative opportunities with other leading laboratories nationally and internationally. Past and current trainees have been extremely successful in obtaining grant funding and fellowships.

Application Deadline: Open Until Filled

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15. Postdoctoral PositionĀ 

Summary of Postdoctoral Fellowship:

A postdoctoral associate position is available in the laboratory of Dr. Jennifer Trowbridge at The Jackson Laboratory in Bar Harbor, Maine, to perform basic and translational research investigating the biological mechanisms that cause, and may be targeted to prevent, functional decline of blood and immune systems during aging. This work may include studies of aging hematopoietic stem cells as well as alterations in the bone marrow microenvironment with aging. The Trowbridge Lab offers a teamwork environment including collaborative opportunities with other leading laboratories in this field, nationally and internationally. Past and current trainees have been extremely successful in obtaining grant funding and fellowships.

Application Deadline: Open Until Filled

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16. Postdoctoral PositionĀ 

Summary of Postdoctoral Fellowship:

The West lab is relocating to The Jackson Laboratory and is seeking an independent, highly motivated postdoctoral fellow to lead a collaborative research program to investigate how mitochondrial dysfunction potentiates disease-associated inflammation. The overall goals of our laboratory are to delineate how mitochondria function as central regulators of innate immune and inflammatory responses and to investigate how mitochondria-immune crosstalk contributes to disease and aging. Our laboratory pursues a multidisciplinary approach by integrating cell biology, immunology, and physiology using cutting-edge techniques including engineered mouse models, single-cell multi-omics, super-resolution imaging, and CRISPR-based cellular tools.

Application Deadline: Open Until Filled

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17. Postdoctoral PositionĀ 

Summary of Postdoctoral Fellowship:

The Hinson lab is seeking an independent, highly motivated PhD-level scientist to join our trans-continental collaborative group funded by the Human Frontiers Science Program (HFSP). The overarching goal of this project is to leverage human pluripotent stem cell technology and advanced structural biology methods to define mechanisms and rules of sarcomere assembly and function. The ideal candidate would have a strong background in cell and molecular biology particularly in stem cell differentiation, advanced imaging and protein-protein interaction studies. As part of the group, this talented individual would have access to a world-class consortium of scientists across pluripotent stem cell biology, 3-dimensional organoids/microtissue assays, super resolution microscopy, and structural biology.

Application Deadline: Open Until Filled

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18. Postdoctoral PositionĀ 

Summary of Postdoctoral Fellowship:

The labs of Drs. Erik Bloss and Gareth Howell at The Jackson Laboratory in Bar Harbor, Maine are seeking a postdoctoral fellow to investigate the role microglia in modulating the health of neural circuits during aging and in Alzheimerā€™s disease. The Bloss lab leverages high resolution imaging and observation/manipulation of neural activity in vivo with genetic perturbations in specific neurons to identify the principles governing neural circuits function in health and disease. The Howell lab utilizes genetic tools alongside multi-omic approaches to define the role of microglia in neurodegenerative diseases including Alzheimerā€™s disease and related dementias (ADRDs). This position will benefit from joint mentoring from Drs. Bloss and Howell to identify microglia-specific genes and pathways that drive synaptic, neural circuit, and cognitive dysfunction in aging and ADRDs.

Application Deadline: Open Until Filled

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19. Postdoctoral PositionĀ 

Summary of Postdoctoral Fellowship:

We are looking for talented, intellectually curious postdoctoral candidates to embark on a unique postdoctoral training experience that leverages the rich domain expertise, mouse resources, and data services of JAXā€™s Center for the Addiction Biology, which includes the NIDA funded Center for Systems Neurogenetics of Addiction and other addiction research programs. As part of the Addiction Center team, the postdoctoral associate will contribute to innovative discoveries through application of their versatile technical expertise and domain knowledge. Engaging postdocs across disciplines and specific domain areas allows jointly mentored postdocs to expand their skill sets in emerging, interdisciplinary research areas.

Application Deadline: Open Until Filled

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20. Postdoctoral PositionĀ 

Summary of Postdoctoral Fellowship:

The Tewhey Lab at The Jackson Laboratory in Bar Harbor, Maine is seeking a Postdoctoral Associate to join our team of scientists working to understand the precise genetic mechanisms underlying complex traits, and the impact human genetic variation has on gene regulatory function. Our group develops and applies novel high-throughput genetic techniques (e.g. MPRA and CRISPR based screens) to comprehensively characterize non-coding regions of the genome, in both mouse and human, to interpret the regulatory grammar of gene expression.

Application Deadline: Open Until Filled

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21. Postdoctoral PositionĀ 

Summary of Postdoctoral Fellowship:

A postdoctoral associate position is available in the laboratory of Dr. Elissa Chesler at The Jackson Laboratory in Bar Harbor, Maine to utilize systems genetics approaches to identify heritable effectors of behavior. The Chesler lab uses quantitative genetics, bioinformatics and behavioral science to understand and identify the biological basis for the relationships among behavioral traits with an emphasis on alcohol and substance use related traits. We develop and apply cross-species genomic data integration, advanced computing methods, and novel high-precision, high-diversity mouse populations to find genes associated with a constellation of behavioral disorders and other complex traits.

Application Deadline: Open Until Filled

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