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16 Postdoctoral Fellowships at St. Jude Children’s Research Hospital, Tennessee

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St. Jude Children’s Research Hospital, Tennessee, USA invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.

1. Postdoctoral Position in Cell & Molecular Biology

Summary of Postdoctoral Fellowship:

A postdoctoral (Scientist) position is available immediately in the Chang lab in the Department of Cell & Molecular Biology at St. Jude Children’s Research Hospital. We are looking for highly talented, self-motivated individuals passionate about how cells function as integrated units. In particular, the candidate will utilize cutting-edge light and electron microscopy tools together with genome-editing, biochemistry and in vitro reconstitution to interrogate the fundamental questions of inter-organelle communication. Interested applicants should send a CV, cover letter describing why they are interested in working in our lab, and the names and address of 3 references to Chi-Lun.Chang@stjude.org.

Application Deadline: Open Until Filled

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2. Postdoctoral Position in Pediatric Neurological Disorder Research

Summary of Postdoctoral Fellowship:

The McKinnon lab within the CPNDR has postdoctoral positions to study the pathogenesis of pediatric neurological disease. The lab employs state of the art molecular neuroscience and multi-omics approaches to understand the mechanistic bases of various neurodegenerative syndromes arising from defective genome maintenance. Available postdoctoral projects include understanding the pathogenesis of genome instability induced neuroinflammation in a model of Aicardi Goutières syndrome (see Neuron, PMID: 34655526), the role of genome architecture in determining susceptibly of specific neural populations to genome damage (see Science Adv., PMID: 34910524) and elucidating the critical role of genome maintenance during neurogenesis (e.g see PMIDs 27630045, 30538199, 24793032, 26290337). Interested individuals with an extensive neuroscience background who are experienced in current molecular biology techniques are encouraged to apply. Please email a CV including the names of three references to: peter.mckinnon@stjude.org

Application Deadline: Open Until Filled

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3. Postdoctoral Position in Infectious Disease

Summary of Postdoctoral Fellowship:

St. Jude is seeking outstanding candidates for postdoctoral fellowship positions in infectious disease therapeutics. This NIH sponsored training program has been designed to leverage the outstanding research infrastructure at St. Jude to train top-tier postdoctoral fellows with the necessary skills to lead independent research programs in the discovery of infectious diseases therapeutics including small molecule and vaccine candidates. Postdoctoral preceptors associated with the program are drawn from the departments of Infectious Diseases, Structural Biology, Chemical Biology & Therapeutics, Immunology and Pharmaceutical Sciences, bringing complementary expertise to this enterprise that not only seeks to understand the biology of infection but also strives to develop therapies to combat them.

This expertise includes structural biology, virology and bacteriology, microbial genomics, drug discovery, high-throughput screening, medicinal chemistry, immune responses to infection and therapies, and vaccine platforms and adjuvants. All trainees will be instructed in grant writing, rigor and reproducibility, ethics and mentoring. Short-term internships in pharmaceutical companies or visits to international clinical sites in conjunction with the SJCRH Global Program are integral parts of the curriculum.

Application Deadline: Open Until Filled

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4. Postdoctoral Position in Neurological Disease Research

Summary of Postdoctoral Fellowship:

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Application Deadline: Open Until Filled

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5. Postdoctoral Position in Oncology

Summary of Postdoctoral Fellowship:

Dr. Roberts’ research is highly regarded and he has been elected to the American Association of Clinical Research, the Society for Pediatric Research, the American Pediatric Society and American Association of Physicians. He is a passionate mentor and is fully committed to training the next generation of scientists. In addition to being the Director of the NCI designated St. Jude Comprehensive Cancer Center, Dr. Roberts leads a very successful well-funded team with postdoctoral scientists, graduate students, technologists, senior scientists, and a dedicated bioinformatician. You will receive outstanding training in the development of scientific thinking and other skills such as grant writing, manuscript writing, and effective presentation, as well as have the freedom to develop your own ideas in a rigorous and supportive environment. Previous postdocs and graduate student trainees have successfully pursued careers as leaders in academia and industry. A list of previous trainees is available upon request.

Application Deadline: Open Until Filled

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6. Postdoctoral Position in Cell & Molecular Biology

Summary of Postdoctoral Fellowship:

The laboratory of Dr. Bryan Gibson in the Department of Cell and Molecular Biology at St. Jude Children’s Research Hospital invites applications for a Postdoctoral Research Associate to study phase transitions and genome organization. Postdoctoral scientists in the Gibson lab will have the opportunity to become proficient in, and employ, state-of-the-art methodologies in microscopy, genomics, and biochemistry in a scholarly, supportive, and collaborative research environment. They will also have access to core research facilities and substantial resources to aid their pursuit of scientific advances in the fields of chromatin biology and biomolecular condensation. Applicants with interest can explore recent and relevant work published in Nature (DOI: 10.1038/s41586-022-05027-y) and Cell (DOI: 10.1016/j.cell.2019.08.037). Applicants should send (1) a CV with contact information for 3 references and (2) a cover letter describing their scientific journey to Dr. Bryan Gibson (email: bryan.gibson@stjude.org).

Application Deadline: Open Until Filled

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7. Postdoctoral Position in Cell & Molecular Biology

Summary of Postdoctoral Fellowship:

Postdoctoral positions are available in the laboratory of Dr. Stacey Ogden at St. Jude Children’s Research Hospital to research mechanisms of Sonic Hedgehog signaling during development. We are particularly interested in understanding how Sonic Hedgehog ligands use specialized filopodia called cytonemes to travel from their sites of synthesis to activate signaling on distantly localized target cells. Other focus areas in the laboratory include investigations centered on how Sonic Hedgehog signaling is activated in signal-receiving cells and how GLI transcriptional effectors are regulated to ensure appropriate transcriptional responses occur downstream of ligand. We use genetic model systems and cutting-edge imaging technologies to interrogate these fascinating cell biological questions. Prior experience with mouse models and confocal microscopy is preferred, but not required.

Application Deadline: Open Until Filled

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8. Postdoctoral Position in Cell & Molecular Biology

Summary of Postdoctoral Fellowship:

Postdoctoral positions are available in the laboratory of Dr. Stacey Ogden at St. Jude Children’s Research Hospital to research mechanisms of Sonic Hedgehog signaling during development. We are particularly interested in understanding how Sonic Hedgehog ligands use specialized filopodia called cytonemes to travel from their sites of synthesis to activate signaling on distantly localized target cells. Other focus areas in the laboratory include investigations centered on how Sonic Hedgehog signaling is activated in signal-receiving cells and how GLI transcriptional effectors are regulated to ensure appropriate transcriptional responses occur downstream of ligand. We use genetic model systems and cutting-edge imaging technologies to interrogate these fascinating cell biological questions. Prior experience with mouse models and confocal microscopy is preferred, but not required.

Application Deadline: Open Until Filled

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9. Staff Biostatistician (Multiple Openings)

Summary of Postdoctoral Fellowship:

St. Jude Children’s Research Hospital is seeking motivated biostatistics professionals to join our team, and further our life-saving mission. We have multiple positions available within the Department of Biostatistics. Successful candidates will be hired into the career level for which they qualify, based on their education and experience. The Biostatisticians at St. Jude will have a direct impact on the mission of St. Jude by providing statistical expertise to researchers conducting clinical and experimental studies. The Department of Biostatistics is a large department with 14 faculty, 26 biostatisticians, 3 postdoctoral fellows, 8 computing professionals, and administrative staff. Biostatisticians work in teams with a faculty member and sometimes with other biostatisticians to support assigned specific research areas. This approach enables them to gain disease-specific knowledge and expertise while also building productive relationships with collaborators across St. Jude.

Application Deadline: Open Until Filled

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10. Postdoctoral Position in Oncology

Summary of Postdoctoral Fellowship:

The Obeng Laboratory is seeking creative and highly motivated candidates for a fully supported postdoctoral fellowship studying the pathogenesis of myeloid malignancies. The major interests of the lab are determining how acquired mutations in hematopoietic stem cells lead to the development of clonal hematopoiesis, myelodysplastic syndrome, and leukemia, in addition to identifying and studying novel treatments that selectively target malignant clones.

Application Deadline: Open Until Filled

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11. Postdoctoral Position in Developmental Neurobiology

Summary of Postdoctoral Fellowship:

The Plummer Lab at St Jude’s is searching for a Postdoctoral Scientist with a strong background in tumor biology and genomics. This position will manage a team of laboratory technicians to process samples for profiling with single cell OMICs and spatial technologies. Our laboratory analyzes various clinical samples with emerging technologies and expect our analysis to lead to high profile publications in top tier scientific journals. The Plummer lab is a site for the Human Cell Atlas where we focus on understanding the development of disease by studying the cells of origin for neurodevelopmental disorders and breast/prostate/ovarian cancer. If you are interested in breakthrough research and implementing new research techniques, protocols and analyse/interpret data, come consider a close cooperation with Dr. Plummer and other Research Scientists including a high level Bioinformatics Team. Please send inquiries to jasmine.plummer@stjude.org

Application Deadline: Open Until Filled

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12. Postdoctoral Position in Computational Biology

Summary of Postdoctoral Fellowship:

The Yu Lab in the Department of Computational Biology is seeking outstanding candidates for a postdoctoral research associate focused on spatial omics and systems immunology. The Yu Lab is interested in developing systems biology algorithms, including NetBID (Du et al., Nature 2018), by integrating multi-omics data at both bulk and single-cell levels, to dissect the intracellular and intercellular network wiring and rewiring in healthy and disease conditions, as well as the underlying hidden drivers, and then translate the discoveries into potential clinical applications.

The candidate will develop computational and systems biology approaches for network and hidden driver analysis from spatial omics data, single-cell omics data (e.g., scRNA-seq, scATAC-seq, single-cell proteomics, and spatial transcriptomics). The successful applicant will work in a dynamic environment, performing integrative analysis of multidimensional datasets in the context of basic immunology and cancer immunotherapy.

Application Deadline: Open Until Filled

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13. Postdoctoral Position in Neuronal Cell Biology – Vevea Lab

Summary of Postdoctoral Fellowship:

A postdoc position is available in the Vevea lab at St. Jude Children’s Research Hospital in the Department of Developmental Neurobiology and Neuronal Cell Biology Division. We are a cell biology lab that leverages advanced imaging and biochemical techniques to examine the synaptic vesicle cycle in the context of basic function, human disease, and aging. Experiments will include live-neuron microscopy (light-sheet, biosensor), ICC (dSTORM), and a new rapid immunoprecipitation technique.

Potential projects include 1) characterization of synaptic organelles (i.e., mitochondria, synaptic vesicles) using newly developed rapid IP technique, 2) acute disruption and characterization of alpha synuclein at the presynapse, and 3) the role of presenilin mutations in the localization and trafficking of synaptotagmin 7. We are a new lab and so this position can shape the future of all research that comes out of the lab. Would you like to use and design novel techniques, use a ton of institute core facilities?

Do you have a passion for neuronal cell biology? Please get in touch with me. St. Jude as an institute is incredibly supportive and offers a signing bonus and a work computer on arrival, among many other competitive benefits. Special instructions: If interested, please send a brief statement about yourself (cover letter) no more than a paragraph and a CV to Jason Vevea (PI) at jvevea@wisc.edu.

Application Deadline: Open Until Filled

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14. Postdoctoral Position in Pharmaceutical Sciences

Summary of Postdoctoral Fellowship:

A post-doctoral position is available in the laboratory of David Rogers in the field of molecular mycology in the area of antifungal drug resistance. The overarching goal of the Rogers lab is to utilize genome-wide and molecular biological approaches to understand the molecular and genetic basis of antifungal drug resistance in pathogenic opportunistic fungi. The long-term goal of this project is to advance the treatment of Candida infections by identifying the molecular mechanisms underpinning antifungal resistance in Candida species and to ultimately use this understanding to design therapeutic strategies to overcome them. Our immediate objective is to fully understand the genetic and molecular basis of antifungal resistance in clinical isolates of C. albicans, C. glabrata, and C. auris.

Application Deadline: Open Until Filled

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15. Postdoctoral Position in Oncology

Summary of Postdoctoral Fellowship:

The Durbin Lab in the Division of Molecular Oncology at St. Jude Children’s Research Hospital studies the fundamental mechanisms that drive children’s cancer. While patient outcomes have improved in some malignancies, pediatric solid tumors in particular continue to be difficult to manage with little improvements over the past decades. For most of these diseases, no targeted therapies are available, and unfortunately, conventional therapies are fraught with toxicities.

With advances in functional genomics, the role of epigenetic enzymes and transcription factor complexes in driving cell lineage and cancer pathogenesis has come to the forefront. These represent new approaches to controlling high-risk childhood solid tumors, such as neuroblastoma. These processes are made more complex by the presence of intratumoral heterogeneity – the presence of cells in distinct states, within a complex primary tumor (Cell Reports Medicine 2022). Understanding the basic principles of how these cells interact to control growth of a tumor is critical to the successful design of new therapeutic interventions for childhood cancer (Molecular Cell 2020).

Application Deadline: Open Until Filled

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16. Postdoctoral Position in Pharmaceutical Sciences

Summary of Postdoctoral Fellowship:

The laboratory of Dr. Peijun Ma in the Department of Pharmacy and Pharmaceutical Sciences in St. Jude Children’s Research Hospital, Memphis, TN is a new research group that uses single-cell genomics and transcriptomics to study antibiotic resistance and persistence in bacterial pathogens. Past work has focused on developing bacterial single-cell RNA sequencing technology and understanding the evolution of antibiotic resistance in gram-negative bacterial pathogens.

Application Deadline: Open Until Filled

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