Cold Spring Harbor Laboratory, New York, USA invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.
1. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Zador lab has an opening for a postdoctoral fellow in neuroscience who will be part of the International Brain Laboratory (IBL). The IBL is a large-scale international collaboration in brain research, which combines the efforts of approximately 50 scientists in 22 laboratories toward understanding the brain-wide basis of a mouse visual decision-making task. The overall goal of this postdoc’s project will be to relate single neuron connectivity, gene expression and neural activity in the context of in the context of the IBL behavior, to better understand the contributions of different neuronal types to the IBL task. Specifically, the project will involve combining electrophysiological and imaging approaches (widefield and two-photon, including a mesoscope) with new approaches for high-throughput circuit/genomic approaches (including BARseq and MAPseq) developed in the Zador lab.
Application Deadline: Open Until Filled
2. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Yeh Laboratory at CSHL Cancer Center is looking for a postdoctoral fellow to carry out a new drug discovery project harnessing stapled peptide technology and diversity-oriented synthesis. The Yeh Lab is a highly-collaborative environment with state-of-the-art facilities and expertise in biotherapeutics engineering and chemical biology. The Yeh Lab also engages in several close collaborations with other research groups in CSHL. The postdoctoral fellow will enjoy the highly intellectual, cross-disciplinary and collaborative interactions at CSHL.
Application Deadline: Open Until Filled
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3. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Levy and Wigler research groups at Cold Spring Harbor Laboratory, NY are seeking independent and motivated researchers in Computational Biology and Bioinformatics. The successful candidate will have a key role in a multi-disciplinary team of wet-bench and computational researchers working to revolutionize cancer detection and treatment by developing novel genomic technologies. The candidate will work closely with bench scientists to draft the initial computational workflows to analyze new experimental data. Developing a relationship of feedback and understanding between the bench and the computer is essential to work of our groups.
Application Deadline: Open Until Filled
4. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A postdoctoral fellow position is available in the laboratory of Dr. Linda Van Aelst, Professor at Cold Spring Harbor Laboratory. The main focus of research will be to study the roles of genes associated with human diseases in the development and function of neural circuits, using molecular, genetic and viral engineering, optogenetics, imaging, electrophysiology, and behavior analysis.
Application Deadline: Open Until Filled
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5. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A postdoctoral position is immediately available at Cold Spring Harbor Laboratory for highly motivated Ph.D. candidates to join the Tonks Laboratory at CSHL. Protein Tyrosine Phosphatases and the Regulation of Cell Signaling: from Basic Research to New Therapeutics The protein phosphatases are critical, specific regulators of signaling that serve an essential function, in a coordinated manner with the protein kinases, to determine the response to a physiological stimulus. The Tonks Lab takes a multidisciplinary approach to study the structure, regulation and function of the protein tyrosine phosphatase (PTP) family of enzymes, to illustrate their fundamental importance to the control of signal transduction under normal and pathophysiological conditions.
Application Deadline: Open Until Filled
6. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Tollkuhn Lab has an open position for a postdoctoral researcher to develop projects on hormonal regulation of brain sexual differentiation The lab studies how gonadal hormones such as estrogen and testosterone regulate brain development, behavior, and disease. These hormones modulate the wiring of social behavior circuits during developmental sensitive periods to produce sex-variable behaviors in adulthood. Our lab is seeking a colleague with a background in neural development to explore how sex differences in gene expression give rise to sex-typical patterns of neuronal connectivity.
Application Deadline: Open Until Filled
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7. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Tollkuhn Lab has an open position for a postdoctoral researcher to develop projects on hormonal regulation of gene expression in the brain. The lab studies the transcriptional mechanisms of nuclear receptors in the context of brain development, behavior, and disease. Gonadal hormones such as estrogen and testosterone are the principal regulators of sex differences in the vertebrate brain, but the regulatory strategies used by hormone receptors in the brain remain largely unexplored. Our lab has recently published the first neural direct targets of estrogen receptor alpha (ER?), and we now seek a colleague with expertise in gene regulation and the epigenome, who can expand on this line of research.
Application Deadline: Open Until Filled
8. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A postdoctoral position in COMPUTATIONAL GENOMICS is available in Dr. Adam Siepel’s research group at the Simons Center for Quantitative Biology (SCQB), Cold Spring Harbor Laboratory. The Siepel Group specializes in the development of probabilistic models and algorithms for inference, machine-learning methods, and applications in large-scale genomic data analysis. Of particular interest is research relevant to existing NIH-supported projects in:
1. EVOLUTIONARY GENOMICS of humans and other mammals, including inference of ancestral recombination graphs, detection of selective sweeps, comparative genomics of bats, inference of distributions of fitness effects and quantification of genetic load from linked deleterious alleles; and
2. TRANSCRIPTIONAL REGULATION in mammals, including quantification of initiation and pause-release rates from nascent RNA sequencing data, characterization of elongation rates, and evolutionary analysis of transcriptional regulation across primates and other mammals.
Application Deadline: Open Until Filled
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9. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A post-doctoral position is available at the Schorn lab, Cold Spring Harbor Laboratory, NY. We are interested in how small RNAs identify and silence transposable elements when they become active during mammalian development and disease. We found that tRNA fragments (tRF) derived from the 3’-end of mature tRNAs are highly expressed in cells undergoing epigenetic reprogramming and target LTR-retroelements, or endogenous retroviruses (ERVs), at their conserved tRNA primer binding site (PBS).
Due to the perfect sequence complementarity of 3’-tRFs to the PBS, they have tens of thousands of targets in mammalian genomes. 3’-tRFs are processed under yet unknown conditions and potentially protect many eukaryotes. This is an exciting new field with many opportunities! We believe tRFs are an ancient link between RNAi, transposons and genome stability.
Application Deadline: Open Until Filled
10. Postdoctoral Position
Summary of Postdoctoral Fellowship:
We seek a highly motivated, creative, and interactive scientist. Furthermore, we encourage candidates interested in developing new chemistry and biochemistry methods. The candidate must have a strong track record in synthetic organic chemistry, preferably with knowledge of drug discovery and biological assays. Molecular modeling skills are also desirable. You will have the ability to grow with the team and make essential contributions to the collaborative research environment.
Application Deadline: Open Until Filled
11. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A post-doctoral position in computational biology is available in David McCandlish’s group in the Simons Center for Quantitative Biology at Cold Spring Harbor Laboratory. Research in the McCandlish laboratory is focused on the analysis of high-throughput mutagenesis data, with the goal of accurately predicting the phenotypic, health, and evolutionary consequences of both single and multiple mutations in protein coding and regulatory sequences. The group has a particular emphasis on understanding complex genetic interactions and the structure of the genotype-phenotype map.
Application Deadline: Open Until Filled
12. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Martienssen laboratory at Cold Spring Harbor has an opening for a postdoctoral fellow to study the mechanisms of epigenetic inheritance in fission yeast and mammalian cells, recently funded by the National Institutes of Health. RNA interference impacts inheritance and genome stability by silencing of repeats, as well as by non-canonical means, and successful applicants will explore the role of epigenetic modifications, phase separation and transcription-replication conflict in different developmental and cell cycle contexts. State-of-the art equipment and facilities are available both within the lab and in outstanding shared facilities.
Application Deadline: Open Until Filled
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13. 02 Postdoctoral Position
Summary of Postdoctoral Fellowship:
Dr. Lingbo Zhang’s Lab at Cold Spring Harbor Laboratory focuses on both basic science and translational medicine of hematologic malignancies. The research of the Lab centers on normal and malignant stem and progenitor cells in the hematopoietic system and decodes the role of metabolites, including micronutrients and neurotransmitters, in the tumor microenvironment and their genetic effectors in regulating hematologic malignancies. There are two fully funded postdoctoral fellowships available to investigate the roles of these critical metabolites and their genetic effectors in hematopoietic malignancies and develop novel therapeutic strategies.
Application Deadline: Open Until Filled
14. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Cold Spring Harbor Laboratory is looking for outstanding candidates to fill postdoctoral positions in theoretical neuroscience. The position is open under specific projects as well as general research involving the application of methods from theoretical physics, mathematics, and machine learning with the goal to understand the brain function.
Application Deadline: Open Until Filled
15. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Koo Lab studies the functional impact of genomic mutations through a computational lens using data-driven machine learning solutions. We are broadly interested in applications for studying gene regulation and protein (dys)function. Our approach develops methods to interpret high-performing deep learning models to distill knowledge that they learn from big, noisy biological sequence data. Our goal is to elucidate biological mechanisms that underly sequence-function relationships, with a broader aim of advancing precision medicine for complex diseases, including cancer.
Application Deadline: Open Until Filled
16. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Justin B. Kinney and Adrian R. Krainer seek a postdoctoral fellow to spearhead a project focused on quantitative signal integration in alternative mRNA splicing. This position is part of an ongoing collaboration between the Kinney Lab and Krainer Lab, the goal of which is to quantitatively understand the readout of pre-mRNA sequence by snRNPs and RBPs, as well as the effects of splice-modifying drugs. The successful candidate will be expected to help design their project’s aims, lead the necessary experimental work, and carry out the primary computational analysis of the resulting data. These studies will primarily focus on splicing in human cell culture and/or in vitro splicing reactions, and will involve a combination of both low-throughput and high-throughput techniques, including massively parallel reporter assays (MPRAs). Novel experimental techniques will be developed as needed.
Application Deadline: Open Until Filled
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17. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A postdoctoral position is available to characterize the role of plasmodesmata in plant development, focusing on cell to cell trafficking of the KNOTTED1/ STM class of homeodomain proteins and associated mRNAs. The position is funded for 3+ years, and the candidate should have experience in arabidopsis molecular genetics and/ or cell biology/ microscopy. Our lab uses state of the art developmental biology, imaging and genomic techniques to understand signaling in plant stem cell (meristem) development, using arabidopsis and maize as model systems.
Application Deadline: Open Until Filled
18. Postdoctoral Position
Summary of Postdoctoral Fellowship:
We are currently seeking innovative, inventive, and self-driven Postdoctoral Associates within the lab of Dr. Leemor Joshua-Tor at Cold Spring Harbor Laboratory. The Joshua-Tor lab studies the structure and mechanism of gene silencing pathways as well as DNA replication. To get a complete understanding of how these processes, the team employs structural, biochemical, biophysical and molecular biology approaches to study how key proteins work at the molecular level.
Application Deadline: Open Until Filled
19. Postdoctoral Position
Summary of Postdoctoral Fellowship:
We are looking for candidates who will develop their own research questions in line with the overarching goals of this program. Substantial resources will be available to the selected candidate, including state-of-the-art laboratory space and the opportunity to discuss science in a diverse and supportive environment. Opportunities to develop skills in the use of murine models of cancer, advanced microscopy, optogenetics/chemogenetics, metabolomics, and biostatistics will be available.
Application Deadline: Open Until Filled
20. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Janowitz Laboratory at CSHL is seeking a highly motivated, creative, and interactive postdoctoral researcher with strong experimental and analytical skills to contribute to research on the connectivity of the host response to cancer. We employ pre-clinical and clinical research to develop and test new treatment strategies and to discover fundamental biological interactions between tumors and host organ systems.
Application Deadline: Open Until Filled
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21. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Furukawa lab has NIH-funded postdoctoral fellow/associate positions available for scientists interested in solving questions in neurobiology and neuro-cancer-immunology by implementing a dynamic range of techniques including structural biology (cryo-EM, x-ray crystallography, molecular dynamics) together with electrophysiology (patch-clamp, slice physiology, lipid bilayer), protein engineering, chemical biology, mouse model, cellular imaging, and cancer mouse model. We have an excellent track record for unraveling detailed mechanisms and developing reagents for ligand-gated ion channels and will be conducting biological researches based on the gained molecular knowledge.
Application Deadline: Open Until Filled
22. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Cold Spring Harbor Laboratory invites applications for a Computational Post Doc in the laboratory of Dr. Alexander Dobin. The successful candidates will join a team of biological data scientists working on novel statistical methods and computational algorithms for multi-omics processing and integration, and leverage Big Genomic Data to elucidate various problems in precision health, such as genetic and epigenetic mechanisms of cancer development and progression, and clinical impact of functional variants.
Application Deadline: Open Until Filled
