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12 Postdoctoral Fellowships at Sanford Burnham Prebys, California

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University of Toronto, Ontario, Canada invites multiple online application for Postdoctoral Fellowships in various research areas. The expected hiring range for this position is $64,480.00 to $70,000.00, commensurate with experience. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.

1. Postdoctoral Position in Epigenetics of Development and Aging

Summary of Postdoctoral Fellowship:

Dr. Adams’ lab investigates the impact of chromatin and epigenetics on cellular senescence, aging and cancer. The lab strives to be highly collaborative with other labs in San Diego, the US and elsewhere, for example collaborating with computational biologists, immunologists, experts in specific mouse models of cancer and aging, and surgeons, pathologists and clinical oncologists.

Application Deadline: Open Until Filled

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2. Postdoctoral Position in Tumor Initiation and Maintenance

Summary of Postdoctoral Fellowship:

We are seeking a highly motivated and skilled Postdoctoral Associate to work in the laboratory of Prof. Eric Wang at the Sanford Burnham Prebys Medical Discovery Institute in La Jolla, CA. The goals of our research program are to develop and advance small molecules to target cancer drivers and modulate the anti-tumor immune response, with the ultimate goal of gaining new biological insights and validating new therapeutic targets. We are particularly interested in candidates with experience in tumor immunology who are interested in applying cutting edge chemical biology approaches to modulating the anti-tumor immune response. The successful candidate will conduct independent research in a supportive, collegial, inclusive, and collaborative work environment.

Application Deadline: Open Until Filled

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3. Postdoctoral Position in Aging, Cancer and Immuno-oncology

Summary of Postdoctoral Fellowship:

An exceptional post-doctoral training opportunity is available postdoctoral in the laboratory of Ze’ev Ronai in the Aging Onco-immunology Program at the Sanford Burnham Prebys Discovery Cancer Center in La Jolla CA. The project will involve the characterization of novel signaling pathways in tumor microenvironment (including immune components) of melanoma that are controlled by ubiquitin ligases (Siah2 or RNF5). Training will engage work with genetic modified mouse models (conditional KO) coupled with extensive work using cell biology and biochemistry techniques.

Application Deadline: Open Until Filled

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4. Postdoctoral Position in Diabetes Research

Summary of Postdoctoral Fellowship:

Postdoctoral position is available in the laboratory of Dr. Pamela Itkin-Ansari to study proinsulin protein-protein interactions in diabetes. We are investigating the hypothesis that alterations in the proinsulin interaction network play a role in Endoplasmic Reticulum (ER) stress and beta-cell failure. The position is based on our recent studies in Diabetes, ELife, and JCEM. The long-term goal of this project is to develop a novel paradigm for improving ER function and proinsulin trafficking in beta-cells to prevent or ameliorate diabetes.

Application Deadline: Open Until Filled

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5. Postdoctoral Position in Degenerative Diseases

Summary of Postdoctoral Fellowship:

We seek a highly motivated postdoctoral associate to study the role of the unfolded protein response (UPR) in AD-associated neuroprotective pathways. The candidate will use a combination of mouse genetics, biochemistry, cell biology, molecular biology, proteomics, and high throughout sequencing technologies to characterize molecular pathways associated with UPR genes in neurodegeneration. The candidate will test whether genetic and pharmacological targeting of UPR-components can prevent proteostatic dysfunction and restore cognitive and synaptic function in pre-clinical models of AD.

Application Deadline: Open Until Filled

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6. Postdoctoral Position in Alzheimer’s disease

Summary of Postdoctoral Fellowship:

Dr. Timothy Huang’s laboratory focuses on understanding how mutations in cell surface proteins such as TREM2 and SORLA can alter neuronal and microglial function. Recent work from our group established a role for SORLA in protecting synaptic function in the presence of Aß (J Exp Med 214: 3669, 2017) as well as enhancing neurite outgrowth (J Neurosci 40: 5908, 2020). The Huang lab also established an ESC-based human microglial modeling platform to determine how AD-related mutations in TREM2 and SORLA can affect microglia behavior and function (J Exp Med 217(12): e20200474, 2020).

Application Deadline: Open Until Filled

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7. Medical Research Scientist in Cell Biology

Summary of Postdoctoral Fellowship:

We have an immediate opening for a highly motivated PhD cell biologist to join our group and study one or more Congenital Disorders of Glycosylation (CDG). These inherited and de novo disorders have muti-systemic presentations ranging from neurological and developmental delay to primordial dwarfism. Our NIH-funded laboratory studies multiple aspects of CDG including discovery and validation of entirely new disorders, exploration of their molecular basis and identification of potential therapies. As a member of a national CDG consortium of researchers, physicians, and family support groups, we have extensive interactions and collaborations with all. CDG families often visit our laboratory.

Application Deadline: Open Until Filled

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8. Postdoctoral Position in Chemistry

Summary of Postdoctoral Fellowship:

A Postdoctoral Chemist position is available to participate in translational research/drug discovery projects focused on the treatment of cancer, central nervous system (CNS) disorders, and infectious diseases. This person will be primarily responsible for scientific activities associated with small molecule drug/probe discovery projects. The Postdoctoral Chemist will be responsible for the design and synthesis of new targets and will interpret biological data to inform compound design. This position is an excellent opportunity to be mentored by industry professionals in an academic setting, and to hone the skills and rigor demanded by Pharma.

Application Deadline: Open Until Filled

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9. Postdoctoral Position in Cell and Molecular Biology of Cancer

Summary of Postdoctoral Fellowship:

We are currently looking for a creative, motivated, and highly skilled Postdoctoral Associate to work in the laboratory of Prof. Nicholas Cosford at the Sanford Burnham Prebys Medical Discovery Institute in La Jolla, CA. As part of the NCI-Designated Cancer Center at Sanford Burnham Prebys, the Cosford lab operates at the cutting edge of chemistry and biology to develop novel therapeutic strategies for major human diseases. The project, funded by multiple NIH grants, will primarily center on studying the biophysical interactions of small molecules and peptides with several protein tyrosine phosphatases involved in cancer, neurological disorders such as Alzheimer’s and Parkinson’s disease, as well as COVID-19-related sepsis and septic shock.

Application Deadline: Open Until Filled

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10. Postdoctoral Position in Drug Discovery

Summary of Postdoctoral Fellowship:

Independently designs and performs experiments and procedures with high degree of complexity, demonstrating increasing expertise with a wide range of techniques. Provides hands-on expertise. Interprets results and evaluates of data from different sources and draws relevant conclusions.

Application Deadline: Open Until Filled

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11. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are recruiting for a Senior Associate Scientist who will be primarily responsible for scientific activities associated with small molecule drug/chemical probe discovery projects under the direction of Dr. Sergienko, and in collaboration with other team leaders within the Conrad Prebys Center for Chemical Genomics (Prebys Center). The candidate will conduct bench research for translational research projects and contribute to advancing viable programs along the drug discovery itinerary. This position is an excellent opportunity to be exposed to a dynamic range of drug discovery research techniques, be mentored by industry professionals in an academic setting, and to hone the skills and rigor demanded by Pharma.

Application Deadline: Open Until Filled

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12. Postdoctoral Position in Cancer Discovery and Translation

Summary of Postdoctoral Fellowship:

Sanford Burnham Prebys is currently accepting applications for postdoctoral training in our exciting T32 Program: Cancer Discovery and Translation Fellowship Program. The goal of this 2-year training program is to establish an innovative multi-thematic graduate student and postdoctoral training program to train the next generation of leaders in cancer discovery, cancer drug discovery, and biomarker development. Through this program, advanced graduate students and postdocs will be trained in the skills needed to execute a successful cancer drug discovery project using novel paradigms and state-of-the-art technologies.

Application Deadline: Open Until Filled

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