City of Hope, California, USA invites multiple online application for Postdoctoral Fellowships (salary: $54,840 – $65,000) in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.
1. Postdoctoral Position in T Cell Therapeutics
Summary of Postdoctoral Fellowship:
The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. The T Cell Therapeutics Research Laboratory (TCTRL) overseen by Stephen Forman, M.D., is a fast-paced lab involved in cutting edge technology, research and clinical immunotherapeutic programs. The TCTRL currently has an opening for a postdoctoral fellow who will develop chimeric antigen receptor T cell therapies. The postdoctoral candidate will ideally have experience in the fields of viral specific T cells and HIV. This position will interact and collaborate with a team of research scientists with similar interests in developing T cell therapies.
Application Deadline: Open Until Filled
2. Postdoctoral Position in Metabolism in Thermogenic Brown Adipocytes
Summary of Postdoctoral Fellowship:
The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow to join the Arthur Riggs Diabetes and Metabolism Research Institute – Department of Molecular and Cellular Endocrinology. Dr. Lei Jiang’s laboratory focuses on the molecular mechanisms regulating central carbon metabolism in adipocytes and lung cancer cells. The application of mathematical- and bioengineering-based modeling prediction and experimental mass spec-based metabolic tracing will provide a better understanding of metabolic rewiring in obesity and cancer. A determined and self-motivated postdoc is encouraged to join Dr. Jiang’s laboratory, to focus on an ongoing study of the fuel metabolism in thermogenic brown adipocytes.
Application Deadline: Open Until Filled
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3. Postdoctoral Position in Immunology and Cancer Therapy Development
Summary of Postdoctoral Fellowship:
We are recruiting enthusiastic, motivated scientists who are seeking a fast-paced, team-based academic research environment. Our lab in the Department of Immuno-oncology focuses on how blood and immune cells develop, function, and interact with other cells, with a second focus on how blood stem cells become malignant. We use mass spectrometry to identify activated protein circuits in rare blood stem and progenitor cell populations, including therapeutic chimeric antigen receptor (CAR) T cells, and combine that knowledge with fundamental immunological principles to improve and devise new therapies for pediatric cancers and blood disorders.
Application Deadline: Open Until Filled
4. Postdoctoral Position in Precision Oncology of Gastrointestinal Cancers
Summary of Postdoctoral Fellowship:
We currently have multiple Postdoctoral Fellowship positions within the multidisciplinary research team headed by Dr. Ajay Goel, Professor and Chair, Department of Molecular Diagnostics and Experimental Therapeutics and Associate Director of Basic Sciences, City of Hope Comprehensive Cancer. Our multidisciplinary research group comprises of basic biologists, gastroenterologists, surgeons, oncologists and bioinformaticians, undertaking a number of collaborative projects involving large international consortia. Our research is focused on translational research as it relates to genomic and epigenomic characterization of various gastrointestinal cancers (GI) including colorectal, pancreatic and gastric cancers.
Application Deadline: Open Until Filled
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5. Postdoctoral Position in Cell Biology and Quantitative Microscopy
Summary of Postdoctoral Fellowship:
A Postdoctoral Fellow Position is available in the laboratory of Dr. Tijana Jovanovic-Talisman. Biological nanoparticles that are continuously shed by cells – namely extracellular vesicles (EVs) – are an emerging and exciting strategy for performing minimally invasive diagnoses. Because EVs are loaded with disease-specific molecules, they represent an excellent source of biomarkers. The project involves employing cell biology and super-resolution microscopy approaches to characterize extracellular vesicles that contain disease-specific or tissue-specific molecules. Ultimately, the goal is to develop a new platform to perform molecular level diagnoses for precision medicine.
Application Deadline: Open Until Filled
6. Postdoctoral Position in Computational Biology, Biostatistics and Bioinformatics
Summary of Postdoctoral Fellowship:
Our research is focused on translational research as it relates to genomic and epigenomic characterization of various gastrointestinal cancers (GI) including colorectal, pancreatic and gastric cancers, and some of the key research topics include: 1) Development of circulating DNA/RNA-based liquid biopsy biomarkers for cancer diagnosis, prognosis and predictive response to various therapies. 2) Study the epigenetic basis of GI cancers (e.g. aberrant DNA methylation, histone modifications and non-coding RNAs. 3) The genetic basis of early-onset and familial/hereditary colorectal cancers.
Application Deadline: Open Until Filled
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7. Postdoctoral Position in Molecular Pathogenesis of Lymphoid Malignancies
Summary of Postdoctoral Fellowship:
The Ngo laboratory at the Department of Systems Biology, City of Hope is seeking a highly motivated Postdoctoral Fellow to lead a federally funded project in lymphoma and immunotherapy. Our laboratory studies molecular mechanisms and identifies therapeutic targets in hematologic malignancies. Candidates having interests in cancer biology and immunology with hands-on experience in working with hematopoietic cells and handling animals are encouraged to apply. Candidates with at least one first-author paper will be given more priority.
Application Deadline: Open Until Filled
8. Postdoctoral Position in Hematology, Immunology, and Cancer Biology
Summary of Postdoctoral Fellowship:
Our group is interested in discovering novel genetic and epigenetic regulations and deciphering their underlying molecular mechanisms in normal developmental processes (e.g., hematopoiesis) and tumorigenesis (e.g., leukemogenesis). We cover research areas with relevance to Hematology, Immunology, and Cancer Biology, with an emphasis on RNA epigenetics (mainly focusing on the N6 methyladenosine (m6A) modification) and DNA epigenetics (mainly focusing on the TET1/2/3-mediated DNA demethylation) associated basic and translational research.
Application Deadline: Open Until Filled
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9. Postdoctoral Position in Lymphoma Genomics and Biology
Summary of Postdoctoral Fellowship:
The department of pathology of the City of Hope Medical center is recruiting a postdoctoral fellow to work with a group of researchers in lymphoma genomics and biology. The candidate is expected to be an innovative scientist with knowledge and experience in molecular biology, cell culture, in vitro functional assays and genomic editing. Some interests and knowledge in the analysis of data generated through next generation sequencing and other global technologies including transcriptomic and mutational analysis as well as correlative analysis of different datasets would be desirable.
Application Deadline: Open Until Filled
10. Postdoctoral Position in Cancer Immunosurveillance and Immunotherapy
Summary of Postdoctoral Fellowship:
Dr. Mingye Feng’s laboratory at the Beckman Research Institute of City of Hope is looking for a talented and highly motivated Postdoctoral Fellow. Dr. Feng is an awardee of the V Scholar Award from the V Foundation for Cancer Research, the Damon Runyon – Dale F. Frey Award for Breakthrough Scientists from the Damon Runyon Cancer Research Foundation, the K99/R00 Pathway to Independence Award from NIH, and NIH R01 grants. His laboratory employs cutting-edge techniques to understand mechanisms of macrophages in cancer immunosurveillance, identify immune checkpoints and ligands on various hematopoietic malignant and solider tumor cells with high-throughput screening and protein engineering approaches developed in the lab, and develop novel cancer immunotherapies targeting metastatic cancer cells.
Application Deadline: Open Until Filled
11. Postdoctoral Position in Hematology & Hematopoietic Cell Transplantation
Summary of Postdoctoral Fellowship:
The Caligiuri/Yu Laboratory at Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. We are a fast-paced lab involved in cutting-edge technology, research and clinical immunotherapy investigations. We are currently looking for a postdoctoral fellow who will develop chimeric antigen receptor T- and NK-cell therapies in combination with oncolytic viruses for the treatment of solid tumors, especially glioblastoma. The PhD candidate should have experience in the fields of immunology and cancer biology with a strong track record. This position will interact and collaborate with a team of researchers with similar interests in developing cell-based therapies in a translational research environment.
Application Deadline: Open Until Filled
12. Postdoctoral Position in DNA Replication and Repair
Summary of Postdoctoral Fellowship:
The Shen laboratory has been focusing on DNA replication/repair pathway components, cancer genetics and epigenetics, and cancer etiological and therapeutics modeling. Recent Ph.D. graduates or equivalents in the field of biological/medical sciences with ambition for a scientific career and interest in DNA repair and cancer biology and skills in molecular biology are encouraged to apply. Bioinformatics and database mining skills are a plus.
Application Deadline: Open Until Filled
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13. Postdoctoral Position in Biochemistry and Cell Biology
Summary of Postdoctoral Fellowship:
A Postdoctoral position is now available in the laboratory of Dr. Yilun Liu at the Department of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope. Dr. Liu’s research topics include: Dissecting the molecular mechanism by which transcription-associated genomic instability and epigenetic deregulation contribute to developmental abnormalities and cancer. Developing pharmaceutical mechanisms for cancer therapy by targeting enzymes important for preventing the formation of DNA breaks arose during accelerated cell growth such as in cancer cells as well as factors important for the BRCA2 and PARP-dependent repair pathways to keep these DNA breaks unrepaired.
Application Deadline: Open Until Filled
14. Postdoctoral Position in Cancer Genetics and Epigenetics
Summary of Postdoctoral Fellowship:
Dr. David Chen’s research group at the Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. Dr. Chen is the Director of Division of Epigenetics and Transcriptional Engineering at City of Hope. His lab focuses on epigenetic mechanisms, drug resistance, and therapeutic target discovery in cancers using high throughput genetic screens. This laboratory is skilled in high-throughput CRISPR genetic screens for de novo therapeutic target discovery. They also utilize next-generation sequencing (NGS) for epigenomic and transcriptomic analyses (ChIPseq, ATACseq, RNAseq, etc.), and the patient-derived xenograft (PDX) models for in vivo therapeutic efficacy assessments.
Application Deadline: Open Until Filled
15. Postdoctoral Position in Herpesvirus Vaccine Development
Summary of Postdoctoral Fellowship:
Our laboratory invites highly motivated candidates to apply for an interdisciplinary postdoctoral scholar position. Our laboratory focuses on oncogenic herpesviruses, in particular Epstein-Barr virus (EBV), Kaposi-sarcoma associated herpesvirus (KSHV), and the rhesus macaque EBV homologue rhesus lymphocryptovirus (rhLCV), and on developing prophylactic and therapeutic strategies against primary infection with these viruses and their associated cancers. The postdoctoral scholar will be working on projects with the overarching goal of designing and testing gamma herpesvirus vaccine candidates and immuno-therapeutics in various preclinical animal models.
Application Deadline: Open Until Filled
16. Postdoctoral Position in Hematologic Malignancies
Summary of Postdoctoral Fellowship:
A Postdoctoral Fellow position is available in the Vaccine Research Laboratory of Dr Don J Diamond in the Department of Hematology & Hematopoietic Cell Transplantation of the City of Hope. Dr Diamond’s research team is seeking a highly motivated candidate with experience in molecular biology/virology or viral immunology. The position is available as part of multiple research projects to develop COVID-19 and CMV vaccines based on a highly efficient and fully synthetic viral-vectored vaccine platform for pathogen preparedness and disease prevention.
Application Deadline: Open Until Filled
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17. Postdoctoral Position in Cancer Biology
Summary of Postdoctoral Fellowship:
The Wang Laboratory at the Department of Systems Biology, Beckman Research Institute, City of Hope, is seeking for a talented and motivated Postdoctoral Fellow to lead the project for RNA splicing dysregulation, DNA damage response, and oncogenesis in blood malignancies. Candidates with strong background in RNA splicing, DNA damage, cancer biology, animal models, and bioinformatics are encouraged to apply. Wang Laboratory is currently funded by two R01 grants, foundation grants, and City of Hope Startup package.
Application Deadline: Open Until Filled
18. Postdoctoral Position in Lymphoma Research
Summary of Postdoctoral Fellowship:
Dr. Alexey Danilov’s research is focused on the mechanisms of lymphomagenesis and identification of novel therapeutic targets in B-cell lymphoma and other cancers. Following our recent laboratory discoveries, we also explore the immunomodulatory effects of novel targeted agents and aim to harness their potential to enhance the efficacy of immunotherapy and novel cellular therapies.
Application Deadline: Open Until Filled
19. Postdoctoral Position in Translational Medicine
Summary of Postdoctoral Fellowship:
The Williams lab is looking for a highly motivated postdoctoral student interested in working in translational medicine to treat cancer. The overarching goals of the group are to identify and address unmet clinical needs (e.g., on-target, off-tissue toxicities) by rapidly translating novel molecular designs to the clinic. Using an atoms-up approach, our group pioneered the concept and development of tumor-activated IO monoclonal antibodies, leading the formation of Xilio Therapeutics which has two products currently in phase 1/2 clinical trials.
Application Deadline: Open Until Filled
20. Postdoctoral Position in Ovarian Cancer
Summary of Postdoctoral Fellowship:
The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow for translational research in the field of cancer biology and therapy. Ongoing studies are focusing on targeting ovarian cancer tumor microenvironment by conditionally replicative oncolytic virus and development of new agents targeting extrinsic and intrinsic apoptotic pathways.
Application Deadline: Open Until Filled
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21. Postdoctoral Position in Precision Oncology of Gastrointestinal Cancers
Summary of Postdoctoral Fellowship:
We are seeking multiple Staff Scientists to become a part of the multidisciplinary research team headed by Dr. Ajay Goel, Professor and Chair, Department of Molecular Diagnostics and Experimental Therapeutics. Our research group comprises of basic biologists, gastroenterologists, surgeons, medical oncologists and bioinformaticians, undertaking a number of collaborative projects involving large international consortia. Our research is focused on translational research as it relates to genomic and epigenomic characterization of various gastrointestinal cancers (GI) including colorectal, pancreatic and gastric cancers.
Application Deadline: Open Until Filled
22. Postdoctoral Position in Cutaneous T cell Lymphoma
Summary of Postdoctoral Fellowship:
Dr. Querfeld’s laboratory investigations are focused on the microenvironment in CTCL funded by NIH-NCI R01 and LLS scholar grants. She has demonstrated that cancer growth is fostered by the surrounding nonmalignant cells. These observations have led to the initiation of several targeted and immunologic therapies to restore the immune system and hereby killing the cancerous cells. Examples include a microRNA (miR155) antagomir that inhibits proliferation, an anti-CD47 construct enhancing macrophage killing and a randomized investigator initiated trial comparing the checkpoint inhibitor anti-PD-L1 with/without the immunomodulatory drug lenalidomide.
Application Deadline: Open Until Filled
23. Postdoctoral Position in Computational Approaches in Cancer Biology and Genomics
Summary of Postdoctoral Fellowship:
One full-time postdoc position is available at Dr. Yun Rose Li’s laboratory at Beckman Research Institute, City of Hope. Dr. Li is a physician scientist in radiation oncology whose research integrates genetic epidemiology, innovative sequencing and bioinformatics technologies, molecular biology approaches using cell-based and animal models, and biomarker studies from patients enrolled in clinical trials to better understand the role of oxidative stress in cancer risk and treatment response. The prospective candidates should be highly self-motivated, creative, and capable of working independently and in a team.
Application Deadline: Open Until Filled
24. Postdoctoral Position in Protein Engineering in T Cell Therapeutics Research
Summary of Postdoctoral Fellowship:
The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. The T Cell Therapeutics Research Laboratory (TCTRL) overseen by Stephen Forman, M.D., is a fast-paced lab involved in cutting edge technology, research and clinical immunotherapeutic programs. The TCTRL currently has an opening for a postdoctoral fellow who will develop chimeric antigen receptor T cell therapies and other immunotherapies for the treatment of cancer. The postdoctoral candidate will ideally have expertise in the field of protein engineering, particularly with experience engineering antibodies or other binding moieties. Experience with yeast surface display or other display technologies (e.g. phage display, ribosome display, etc.) is required.
Application Deadline: Open Until Filled
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25. Postdoctoral Position in Immunotherapy for Solid and Hematologic Malignancies
Summary of Postdoctoral Fellowship:
A Postdoctoral Fellow position is available in the laboratory of Edwin R. Manuel, PhD, at City of Hope, Beckman Research Center, Monrovia, CA. Our lab is interested in utilizing tumor-colonizing, bacterial-based agents as novel immunotherapy for solid and hematologic malignancies. We are recruiting enthusiastic, motivated scientists who are seeking a fast-paced academic research environment. Our lab in the Department of Immuno-Oncology focuses on engineering tumor-colonizing bacteria to target components of the tumor microenvironment that contribute poor drug delivery, immune suppression and cancer metabolism.
Application Deadline: Open Until Filled
26. Postdoctoral Position in Protein Chemistry, Crystallography and Structure Determination
Summary of Postdoctoral Fellowship:
The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. The Williams Research Team seeks a self-motivated, results-driven postdoc to drive the development of the generation of therapeutic monoclonal antibodies. Expertise required include thorough knowledge of protein engineering (cloning, expression, purification), crystallography (crystallization, optimization, data collection and structure determination), biochemistry (enzyme kinetics) and biophysics (Surface Plasmon Resonance, Iosthermal Ttitration Calorimetry, etc).
Application Deadline: Open Until Filled
27. Postdoctoral Position in Biological Mechanisms of Breast Cancer Susceptibility
Summary of Postdoctoral Fellowship:
Join our successful and productive research team at the Beckman Research Institute at City of Hope where we are studying the biological mechanisms of breast cancer susceptibility in the context of aging. This current position is focused on using cell and molecular techniques to examine emergent mechanical properties of epithelial cells that are highly susceptible to breast cancer initiation. This mechanobiology work is the product of a long-term, NIH funded, collaboration with a bioengineering group at UC Berkeley. We are using, and evolving, a mechano-node pore sensing (mechano-NPS) platform to explore unique mechanical properties of cells that are associated with chronological or biological age, lineage, and cancer progression stage.
Application Deadline: Open Until Filled
28. Postdoctoral Position in COVID-19 and CMV Vaccines Development
Summary of Postdoctoral Fellowship:
A Postdoctoral Fellow position is available in the Vaccine Research Laboratory of Dr. Don Diamond in the Department of Hematology & Hematopoietic Cell Transplantation of the City of Hope. Dr. Diamond’s research team is seeking a highly motivated candidate with experience in molecular biology/virology or viral immunology. The position is available as part of multi-disciplinary research projects to develop COVID-19 and CMV vaccines based on a highly efficient and fully synthetic poxvirus-vectored vaccine platform for pathogen preparedness and infectious disease prevention.
Application Deadline: Open Until Filled
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29. Postdoctoral Position in COVID-19 and CMV Vaccines Development
Summary of Postdoctoral Fellowship:
A Postdoctoral Fellow position is available in the Vaccine Research Laboratory of Dr. Don Diamond in the Department of Hematology & Hematopoietic Cell Transplantation of the City of Hope. Dr. Diamond’s research team is seeking a highly motivated candidate with experience in molecular biology/virology or viral immunology. The position is available as part of multi-disciplinary research projects to develop COVID-19 and CMV vaccines based on a highly efficient and fully synthetic poxvirus-vectored vaccine platform for pathogen preparedness and infectious disease prevention.
Application Deadline: Open Until Filled
30. Postdoctoral Position in CRISPR Genetic Screens and Functional Epigenetics
Summary of Postdoctoral Fellowship:
Dr. David Chen’s research group at the Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. Dr. Chen is the Director of Division of Epigenetics and Transcriptional Engineering at City of Hope. His lab focuses on epigenetic mechanisms, drug resistance, and therapeutic target discovery in cancers using high throughput genetic screens. This laboratory is skilled in high-throughput CRISPR genetic screens for de novo therapeutic target discovery. They also utilize next-generation sequencing (NGS) for epigenomic and transcriptomic analyses (ChIPseq, ATACseq, RNAseq, etc.), and the patient-derived xenograft (PDX) models for in vivo therapeutic efficacy assessments.
Application Deadline: Open Until Filled
31. Postdoctoral Position in Developmental and Stem Cell Biology
Summary of Postdoctoral Fellowship:
The Shi laboratory has been well known for stem cell research, including stem cell-based disease modeling and cell therapy development. This laboratory is one of the pioneers in establishing disease models and cell therapies using the human induced pluripotent stem cell (iPSC) platform and has published extensively in this area. Some of the papers published by the Shi laboratories include Shi et al. Nature Reviews Drug Discovery 16: 115-130, 2017; Li et al. Cell Stem Cell 23: 239-251, 2018; Feng et al. Advanced Science 7: 2002155, 2020; Wang, et al. Cell Stem Cell 28: 331-342.e5, 2021; Chen et al. Advanced Science: 8: e2101462, 2021; Cui et al. Nature Cancer 2: 932-949, 2021.
Application Deadline: Open Until Filled
