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33 Postdoctoral Fellowships at City of Hope, California

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Are you holding PhD degree and looking for Postdoctoral Fellowships? City of Hope, California invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.

1. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Brenner laboratory is broadly interested in nicotinamide adenine dinucleotide (NAD) metabolism in health and disease. Active research projects include dysregulation of NAD in cancer, perturbations by nicotine, alterations of the NAD system in rare diseases, and alterations of the NAD system in diabesity, infection and neuropathy. The laboratory uses tools of molecular biology, biochemistry, cell biology, metabolomics and mouse modeling to uncover regulatory systems. Our work has led to dozens of clinical trials in diverse areas including blood pressure regulation, preservation of neurocognitive functions, fatty liver, lactation and recovery from SARS-CoV2.

Application Deadline: Open Until Filled

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2. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for a highly motivated individual in the laboratory of Adolfo Garcia-Ocaña, Professor and Chair of the Department of Molecular and Cellular Endocrinology in the Arthur Riggs Diabetes and Metabolism Research Institute. The candidate will directly work with genetically modified mice, human islets, and mouse models of diabetes to decipher the role of small molecules and signaling pathways in pancreatic beta cell regeneration, protection, and function for diabetes therapy. The candidate will work within a team of highly energized and collaborative research investigators that include research associates, staff scientists and research faculty. Highly productive and innovative research investigators are encouraged to apply.

Application Deadline: Open Until Filled

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3. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are currently seeking highly motivated and talented individuals to fill four postdoctoral positions in the laboratory of Dr. Javier Gordon Ogembo at City of Hope’s Department of Immuno-Oncology. The positions are available in the following areas (check requirements for each area at the bottom):
1. Gamma-herpesvirus vaccine development
2. Gamma-herpesvirus T cell immunology and therapeutics
3. Gamma-herpesvirus protein and antibody structural studies
4. Use of preclinical animal models to assess gamma-herpesvirus entry mechanism and vaccine development.

Application Deadline: Open Until Filled

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4. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The candidate is expected to be an innovative scientist with knowledge and experience in molecular oncology (integrative multiomic data analysis), precision pathology (advanced Assisted image analysis on immunofluorescence-stained slides), Immunohistochemical assays and genomic profiling. Interests and knowledge in the analysis of data generated through next generation sequencing and other global technologies including transcriptomic and mutational analysis as well as correlative analysis of different datasets would be desirable. Our group works very collaboratively in a supportive and stimulatory environment with the goal of understanding the pathogenesis of DNA damage response, discovering novel therapeutic targets, and improving the treatment and outcome of women’s cancer patients.

Application Deadline: Open Until Filled

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5. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Alexey Danilov’s research is focused on the mechanisms of lymphomagenesis and identification of novel therapeutic targets in B-cell lymphoma and other cancers. Following our recent laboratory discoveries, we also explore the immunomodulatory effects of novel targeted agents and aim to harness their potential to enhance the efficacy of immunotherapy and novel cellular therapies.

Application Deadline: Open Until Filled

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6. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. Ya-Huei Kuo, at the Beckman Research Institute of City of Hope, a prestigious NCI-designated Comprehensive Cancer Center. The candidate will directly work on identifying mechanisms contributing to leukemia pathogenesis, immune evasion and therapy resistance; developing novel leukemia therapeutics; and participate in a multidisciplinary team work to study information flow and state-transition at multi-dimensional scales.

Application Deadline: Open Until Filled

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7. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. Zhao Wang at the Beckman Research Institute of City of Hope, a prestigious NCI-designated Comprehensive Cancer Center. The candidate will directly work on heart failure under the conditions of diabetes, obesity, cancer treatment, hypertension, and myocardial infarction. The focus will be on metabolic regulation of cardiac response to stress. The candidate will use both in vivo mouse models and in vivo primary cell culture. Additional molecular biology skills are required.

Application Deadline: Open Until Filled

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8. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our research is focused on translational research as it relates to genomic and epigenomic characterization of various gastrointestinal cancers (GI) including colorectal, pancreatic and gastric cancers, and some of the key research topics include: 1) Development of circulating DNA/RNA-based liquid biopsy biomarkers for cancer diagnosis, prognosis and predictive response to various therapies. 2) Study the epigenetic basis of GI cancers (e.g. aberrant DNA methylation, histone modifications and non-coding RNAs. 3) The genetic basis of early-onset and familial/hereditary colorectal cancers.

Application Deadline: Open Until Filled

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9. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Join our successful and productive research team at the Beckman Research Institute at City of Hope where we are studying the biological mechanisms of breast cancer susceptibility in the context of aging. This current position is focused on using cell and molecular techniques to examine emergent mechanical properties of epithelial cells that are highly susceptible to breast cancer initiation. This mechanobiology work is the product of a long-term, NIH funded, collaboration with a bioengineering group at UC Berkeley. We are using, and evolving, a mechano-node pore sensing (mechano-NPS) platform to explore unique mechanical properties of cells that are associated with chronological or biological age, lineage, and cancer progression stage.

Application Deadline: Open Until Filled

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10. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are looking for a talented and highly motivated Postdoctoral Fellow, to join the Laboratory for Cellular Medicine (LCM), Center for Gene Therapy at the Beckman Research Institute of City of Hope. The candidate will join a well-established group performing cutting-edge research, development and qualification of large-scale processes, and manufacture of products for gene therapy clinical trials, including first-in-human studies with genetically engineered (ge) hematopoietic stem and progenitor cells (HSPC) and T cells.

Application Deadline: Open Until Filled

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11. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Ma lab applies state-of-the-art circadian biology, molecular and cellular biology approaches to diabetes and obesity research, with an ultimate goal to unravel circadian etiologies underlying the current epidemics of metabolic diseases for targeted therapeutic interventions. We have a unique research program in deciphering the mechanistic underpinnings of circadian clock control in metabolic tissue development, growth and functional capacity, focusing on skeletal muscle and adipose tissue biology. Recent projects expand into drug screening platforms to identify clock-targeting small molecules for metabolic disease applications.

Application Deadline: Open Until Filled

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12. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We foster a supportive and nonhierarchical lab structure with an inclusive work environment, promoting open communication, and valuing scientific curiosity and creativity in a collaborative environment. While we encourage independent drive and curiosity, we provide an excellent opportunity to thrive independently. Our resource rich research environment enables research spanning basic biological research to the development of clinical trials.

Application Deadline: Open Until Filled

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13. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow for translational research in the field of cancer biology and therapy. Ongoing studies are focusing on targeting ovarian cancer tumor microenvironment by conditionally replicative oncolytic virus and development of new agents targeting extrinsic and intrinsic apoptotic pathways.

Application Deadline: Open Until Filled

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14. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. Yuman Fong, at the Beckman Research Institute of City of Hope, a prestigious NCI-designated Comprehensive Cancer Center. The candidate will directly work on oncolytic virus project, which involves assessing safety and anti-tumor efficacy of different viral constructs, in vitro and in mice. Oncolytic virotherapy is a major focus of our laboratory. The candidate will be working with our oncolytic poxvirus (CF33) and potentially other viral platforms.

Application Deadline: Open Until Filled

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15. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. Alberto Pugliese, MD in the AR-DMRI Department of Diabetes Immunology. The research is highly translational and primarily focused on human type 1 diabetes. The candidate will participate in several projects. Major ongoing projects are investigating miRNA biomarkers, pancreas pathology, and novel therapeutics, also in the context of the analysis of live pancreas tissue from organ donors obtained from the Network for Organ Donors with Diabetes (nPOD), of which Dr. Pugliese is Executive Co-Director, and in future clinical trials.

Application Deadline: Open Until Filled

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16. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. David Chen’s research group at the Beckman Research Institute of City of Hope is seeking a highly skilled and motivated Postdoctoral Fellow to join their dynamic team. Dr. Chen is a distinguished leader serving as the Director of the Division of Epigenetics and Transcriptional Engineering at City of Hope Cancer Center. The primary focus of his lab revolves around investigating epigenetic mechanisms, drug resistance, and identifying therapeutic targets in various cancers through cutting-edge techniques such as high throughput genetic screens. The lab is proficient in high-throughput CRISPR genetic screens for identifying novel therapeutic targets for cancer treatment. They also leverage next-generation sequencing (NGS) methods like ChIP-seq, ATAC-seq, and RNA-seq for comprehensive epigenomic and transcriptomic analyses and utilize patient-derived xenograft (PDX) models to evaluate the efficacy of potential therapies in vivo.

Application Deadline: Open Until Filled

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17. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Yanhong Shi’s lab is looking for highly motivated and productive postdoctoral fellows for stem cell research projects within the Department of Stem Cell Biology and Regenerative Medicine (Shi laboratory) at Beckman Research Institute of City of Hope located in the county of Los Angeles, California. Candidates interested in this position are encouraged to submit curriculum vitae, brief statement of interests and a list of three references.

Application Deadline: Open Until Filled

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18. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr Ed Boas, at the Beckman Research Institute of City of Hope, a prestigious NCI-designated Comprehensive Cancer Center. We are looking for a biomedical engineer, materials scientist, immunologist, or cancer biologist who can help us develop new minimally invasive cancer therapies, such as new materials or devices for drug delivery into tumors (percutaneous or intra-arterial). We are one of the few interventional oncology groups in the United States with a basic science lab, large animal tumor model, and several active clinical trials, which enables us to translate new discoveries from bench to animal to bedside.

Application Deadline: Open Until Filled

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19. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The candidate will directly work on the novel and ongoing projects on prostatic stem cells and stem cell niches in prostate development and tumorigenesis using “cutting edge” and unbiased analytic tools and unique and innovative genetically engineered mouse models (please see some of the recent publications: PLoS Genet 2020 Jan 13:16(1):e1008588; Development 2021 Jan 11:148(1):dev196048; Development 2021 Oct 1:148(19):dev199738; Nat Commun 2022 Jul 28:13:4364; Nat Commun 2022 Nov 2:13:6552).

Application Deadline: Open Until Filled

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20. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow position is available in Dr. Rupangi Vasavada’s lab in the Department of Translational Research and Cellular Therapeutics in the Arthur Riggs-Diabetes and Metabolism Research Institute at City of Hope. The lab is interested in understanding the pathophysiology of diabetes, assessing the role of extracellular vesicles in Type 1 and Type 2 diabetes as well as in aging. We are targeting specific biological pathways to enhance beta cell health, testing their effects from bench to bedside, to find therapeutics to combat the disease. The lab employs a combination of cellular and molecular techniques, mouse models and patient samples to assess these areas.

Application Deadline: Open Until Filled

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21. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Mingye Feng’s laboratory at the Beckman Research Institute of City of Hope is looking for a talented and highly motivated Postdoctoral Fellow. Dr. Feng is an awardee of the V Scholar Award from the V Foundation for Cancer Research, the Damon Runyon – Dale F. Frey Award for Breakthrough Scientists from the Damon Runyon Cancer Research Foundation, the K99/R00 Pathway to Independence Award from NIH, and NIH R01 grants. His laboratory employs cutting-edge techniques to understand mechanisms of macrophages in cancer immunosurveillance, identify immune checkpoints and ligands on various hematopoietic malignant and solider tumor cells with high-throughput screening and protein engineering approaches developed in the lab, and develop novel cancer immunotherapies targeting metastatic cancer cells.

Application Deadline: Open Until Filled

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22. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our group is interested in discovering novel genetic and epigenetic regulations and deciphering their underlying molecular mechanisms in normal developmental processes (e.g., hematopoiesis) and tumorigenesis (e.g., leukemogenesis). We cover research areas with relevance to Hematology, Immunology, and Cancer Biology, with an emphasis on RNA epigenetics (mainly focusing on the N6 methyladenosine (m6A) modification) and DNA epigenetics (mainly focusing on the TET1/2/3-mediated DNA demethylation) associated basic and translational research. Our research involves experiments with primary human cancer cells, cancer and stem cell transplantation models, mouse genetics, classic molecular, biochemistry and cell biology, functional genomics, signal transduction, and large-scale data analysis and computational biology.

Application Deadline: Open Until Filled

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23. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for a highly motivated individual in the laboratory of Dr. Larry Kwak, at the Beckman Research Institute of City of Hope, a prestigious NCI-designated Comprehensive Cancer Center.

Application Deadline: Open Until Filled

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24. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our research is focused on translational research as it relates to genomic and epigenomic characterization of various gastrointestinal cancers (GI) including colorectal, pancreatic and gastric cancers, and some of the key research topics include: 1) Development of circulating DNA/RNA-based liquid biopsy biomarkers for cancer diagnosis, prognosis and predictive response to various therapies. 2) Study the epigenetic basis of GI cancers (e.g. aberrant DNA methylation, histone modifications and non-coding RNAs. 3) The genetic basis of early-onset and familial/hereditary colorectal cancers.

Application Deadline: Open Until Filled

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25. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Postdoctoral Fellow will work on projects utilizing the latest technologies in long and short-read sequencing for analyses of structural variation and genome assembly. We are equipped with both the PacBio Revio and Oxford Nanopore Promethion long-read sequencers. Our team is skilled in library preparation for long-read sequencing and Hi-C using standard short reads, ensuring an ample supply of data to work with. The fellow will take part in the development of new tools for analyzing long reads and oversee the analysis of larger cohorts of samples.

Application Deadline: Open Until Filled

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26. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Nadia Carlesso’s research is focused on the mechanisms of leukemogenesis and identification of novel therapeutic approaches in poor prognosis T-ALL. Following recent laboratory discoveries, her group is exploring novel approaches to target the microenvironment/oncogene cooperation driving chemoresistance and relapse in T-ALL leukemia stem cells.

Application Deadline: Open Until Filled

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27. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We have a Postdoctoral Fellowship position available in Dr. Ajay Goel’s multidisciplinary research team at City of Hope Comprehensive Cancer. Our team comprises basic biologists, gastroenterologists, surgeons, oncologists, and bioinformaticians, working on collaborative projects with international consortia.

Application Deadline: Open Until Filled

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28. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow Position is available in the laboratory of Dr. Tijana Jovanovic-Talisman. Biological nanoparticles that are continuously shed by cells – namely extracellular vesicles (EVs) – are an emerging and exciting strategy for performing minimally invasive diagnoses. Because EVs are loaded with disease-specific molecules, they represent an excellent source of biomarkers. The project involves employing cell biology and super-resolution microscopy approaches to characterize extracellular vesicles that contain disease-specific or tissue-specific molecules. Ultimately, the goal is to develop a new platform to perform molecular level diagnoses for precision medicine.

Application Deadline: Open Until Filled

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29. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Williams lab is looking for a highly motivated postdoctoral student interested in working in translational medicine to treat cancer. The overarching goals of the group are to identify and address unmet clinical needs (e.g., on-target, off-tissue toxicities) by rapidly translating novel molecular designs to the clinic. Using an atoms-up approach, our group pioneered the concept and development of tumor-activated IO monoclonal antibodies, leading the formation of Xilio Therapeutics which has two products currently in phase 1/2 clinical trials. We also discovered and subsequently developed a unique peptide-Fab interaction that allows us to rapidly functionalize monoclonal antibodies including antibody-drug conjugates, bispecifics including NK and T cell engagers, antibody-based imaging reagents, and switchable CAR T cells.

Application Deadline: Open Until Filled

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30. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Williams Research Team seeks a self-motivated, results-driven postdoc to drive the development of the generation of therapeutic monoclonal antibodies. Expertise required include thorough knowledge of protein engineering (cloning, expression, purification), crystallography (crystallization, optimization, data collection and structure determination), biochemistry (enzyme kinetics) and biophysics (Surface Plasmon Resonance, Iosthermal Ttitration Calorimetry, etc).

Application Deadline: Open Until Filled

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31. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Postdoctoral Fellow will work on projects with a focus on improving accessibility of cancer genomics information and integrating technology to improve health literacy. The Postdoctoral Fellow will participate in ongoing research, with a particular focus on cancer genomics, information technology innovations to improve care, cancer care delivery, data management and analysis, project coordination and management, and writing and preparation of manuscripts and grant applications. Considerable opportunities for mentored professional development including analytic skills for quantitative and qualitative data, writing lead-author papers, and designing, applying for, and conducting grant-funded research.

Application Deadline: Open Until Filled

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32. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow position is available in the laboratory of Dr. Heather McGee, MD, PhD, Assistant Professor in the Departments of Radiation Oncology and Immuno-Oncology in the Beckman Research Institute at City of Hope. Dr. McGee is looking for a post-doctoral fellow who is very motivated to lead exciting scientific projects and test novel hypotheses. The post-doctoral researcher must have a background in tumor immunology, murine tumor models and multicolor flow cytometry.

Application Deadline: Open Until Filled

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33. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Caligiuri/Yu Laboratory at Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. We are a fast-paced lab involved in cutting-edge technology, research and clinical immunotherapy investigations. We are currently looking for a postdoctoral fellow who will develop chimeric antigen receptor (CAR) NK cells derived from induced pluripotent stem cells (iPSCs) or umbilical cord blood NK or hematopoietic stem cells, oncolytic viruses, and bispecific antibodies for the treatment of various hematological malignancies or solid tumors. The PhD candidate should have experience in the field of immunology with a strong track record. This position will interact and collaborate with a team of researchers with similar interests in developing cell-based therapies in a translational research environment.

Application Deadline: Open Until Filled

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