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28 Postdoctoral Fellowships at National Cancer Institute, Maryland

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Are you holding PhD degree and looking for Postdoctoral Fellowships? National Cancer Institute, Maryland invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.

1. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our research focuses on the determination of structures of oncogenic proteins and protein-ligand complexes, with an added interest in the study of protein dynamics and its correlation to function. The projects are split into two main areas of research: determination of protein-ligand structures and high-throughput screening, and structural biology and dynamics. The projects will make use of automation for protein crystallization screening and optimization, followed by cryo-crystallography studies and, if suitable, room-temperature and time-resolved studies. The use of complementary techniques, such as small-angle X-ray scattering, is also expected.

Application Deadline: Open Until Filled

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2. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our laboratory studies cell surface proteins such as glypicans, including GPC1, GPC2, and GPC3, B7-H3 (CD276), and mesothelin as immunotherapeutic targets in solid tumors, such as liver cancer, pancreatic cancer, and childhood cancers. We have utilized molecular and cellular biology, computational structure modeling, RNA sequencing (RNA-seq), and mouse tumor models. We have developed single-domain antibody (nanobody) technology, isolated antibodies targeting tumor-specific epitopes, and engineered CAR or TCR constructs to design novel T cell-based immunotherapies. Some of our research has the potential for direct clinical application.

Application Deadline: Open Until Filled

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3. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow position is available immediately in the Surgical Oncology Program, CCR, NCI. Our group, the Targeted Therapy in Endocrine Cancers Section is seeking a motivated postdoctoral fellow interested in working at the interface of the molecular pathophysiology of cancer progression and therapy of rare human endocrine cancers using multimodal therapy such as small molecule inhibitors and radiotherapy. Our laboratory program is dedicated to studying the identification of novel targeted therapeutics in endocrine cancers and novel cancer drug delivery methods by targeting the tumor microenvironment.

Application Deadline: Open Until Filled

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4. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral position is available in the Viral Recombination Section (VRS), HIV Dynamics and Replication Program (HIV DRP), Center for Cancer Research (CCR). The VRS studies retroviral replication using human immunodeficiency viruses and other retroviruses, with a particular emphasis on the mechanisms of viral RNA biology, specific RNA packaging, virus assembly, and HIV replication. Molecular tools and advanced imaging approaches are used to dissect various aspects of viral replication mechanisms.

Application Deadline: Open Until Filled

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5. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Mili’s research program focuses on the roles of localized mRNAs in mammalian physiology and tumor progression. Our goal is to explore the mechanisms leading to compartmentalized mRNA distributions in the cytoplasm, and to understand how localized mRNA translation influences the function of the encoded proteins and modulates physiological responses. We use multidisciplinary approaches including single-molecule RNA and translation imaging in fixed and live cells, bioengineering methods as well as 3D and in vivo models. 

Application Deadline: Open Until Filled

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6. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

This position offers a unique opportunity to contribute collaboratively to cutting-edge research in the field of cancer therapeutics and precision medicine that spans both basic and translational science objectives. The successful candidates will develop novel bioinformatic machine learning methodologies to: 1) explore cancer-specific genomic, epigenetic, and metabolic alterations, molecular systems pharmacology, and network biology and 2) understand molecular mechanisms of drug response and drug resistance to achieve precision medicine. 

Application Deadline: Open Until Filled

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7. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A computational biology postdoctoral position is available in the Tumor Evolution and Genomics Section within the Cancer Data Science Laboratory (CDSL), CCR, NCI, to participate in a variety of projects on (i) tumor evolution and intratumor heterogeneity, (ii) pharmacogenomics, (iii) immunogenomics and (iv) privacy preserving and secure genomics. Postdocs are expected and encouraged to develop their own project of interest as well. The CDSL offers a large, active, and highly supportive environment for training in computational cancer biology with numerous opportunities to collaborate with both computational and wet lab researchers.

Application Deadline: Open Until Filled

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8. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Cancer Biomaterials Engineering Section at the National Cancer Institute (NCI) is hiring a Postdoctoral Fellow to lead projects in immunomodulatory biomaterials for cancer immunotherapy. The Lab is headed by Dr. Matthew Wolf, and is a multidisciplinary combination of biomaterials science, cancer immunology, and tissue engineering. The Wolf lab studies immune modulatory scaffolds as a local delivery system in cancer immunotherapy, including decellularized extracellular matrix. This specific project aims to decode the immune interactions at the biomaterial-tissue interface during cancer immunotherapy and cancer surgery.

Application Deadline: Open Until Filled

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9. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our group is expanding and we are seeking to fill two post-doctoral positions. We study the functions of human and viral non-coding RNAs in a tumorigenic virus in order to identify pathways instrumental to viral pathogenesis and potentially lead to discovery of novel antiviral and anti-tumor targets. Currently, we are studying the functional significance of a subset of circular RNAs and human genes that are differentially regulated by viral infection. Some non-coding RNA functions of interest include: regulation of infection, immune evasion, cell cycle regulation, and apoptosis.

Application Deadline: Open Until Filled

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10. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral position is available in Dr. Sandra Wolin’s laboratory, located in the RNA Biology Laboratory, National Cancer Institute, National Institutes of Health. We study how noncoding RNAs function, the RNA surveillance pathways that remove defective and harmful RNAs and the mechanisms by which defects in these pathways contribute to diseases such as cancer and autoimmunity. Our approach is multidisciplinary, as we combine molecular biology, genetics, biochemistry and structural biology to discover novel functions for noncoding RNAs and to identify novel RNA surveillance pathways.

Application Deadline: Open Until Filled

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11. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A fully funded postdoctoral position for an experimental biologist is available in Dr. Michael Aregger’s Functional Genomics Section within the Molecular Targets Program at the CCR, NCI, NIH. Our group’s research focuses on how cancer cells rewire gene expression and metabolism to adapt to changing environmental conditions. We apply CRISPR-based genome engineering tools and functional genomics approaches to reveal genetic interactions and cancer dependencies, and to identify regulators of metabolic plasticity in cancer cells. Our lab focuses on developing innovative genetic screening approaches and we have access to state-of-the art facilities including next-generation sequencing, single-cell analysis platforms, mass spectrometry, live cell imaging, microscopy, flow cytometry, natural products and synthetic compound libraries, and animal facilities.

Application Deadline: Open Until Filled

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12. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A post-doctoral position in tumor immunology is available in the lab of Dr. Chen Zhao, Thoracic and GI Malignancies Branch, CCR, NCI in Bethesda, MD. Our research focuses on understanding the complex interactions among tumor cells, immune cells, and microbes in the tumor microenvironment in Non-Small Cell Lung Cancer. We have established genetically engineered mouse models, including the KP model, and advanced tissue imaging (static and intravital imaging) platforms. 

Application Deadline: Open Until Filled

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13. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Wang lab focuses on functional genomics of liver cancer using genome-scale technologies including single-cell analyses paired with several national/international collaborative initiatives and clinical studies. Dr. Wang oversees a basic/translational research program emphasizing new molecular approaches to define tumor subtypes and identify biomarkers for early detection, diagnosis, prognosis and prediction, to delineate the molecular mechanisms of liver cancer with applications towards precision medicine. 

Application Deadline: Open Until Filled

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14. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

This is a postdoctoral fellowship in the Protein Chemistry and Molecular Biology Section of the Molecular Targets Program. 

Application Deadline: Open Until Filled

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15. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Comparative Oncology Program (COP) is seeking highly motivated and collaborative candidates with a background in bioinformatics and comparative cancer genomics. The successful candidate will support studies in osteosarcoma (OS) research initiated under the umbrella of the DOG2 project (Deciphering the Osteosarcoma Genome of the Dog). DOG2 is a multi-omic approach which leverages our high-quality clinically-annotated canine specimen bank collected during the last 4 years of clinical trial activities in dogs with OS. 

Application Deadline: Open Until Filled

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16. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Center for Immuno-Oncology (CIO) Translational Research area at the National Cancer Institute functions as a multidisciplinary and interdisciplinary translational research programmatic effort with the goal of developing novel immunotherapies and immunotherapeutic strategies for cancer. Focus is placed on the development of novel immunotherapeutics, not only as monotherapies, but more importantly, in combination with other immune-mediating modalities, and other conventional or experimental therapies, as part of an immuno-oncology programmatic effort.

Application Deadline: Open Until Filled

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17. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A post-doctoral position is available in the laboratory of Avinash Bhandoola at the National Cancer Institute. The laboratory studies the development of T cells, innate lymphocytes, and thymic epithelial cells. New cellular intermediates in the development of innate lymphocytes were recently described by Dr. Bhandoola’s lab, and we wish to evaluate the role of specific transcription factors in this process. Other work in the laboratory studies regulation of thymus growth, and is focused on identifying new types of thymic epithelial cells and transcription factors important for their function.

Application Deadline: Open Until Filled

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18. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Two postdoctoral positions are available with a starting stipend of $65,100 in the Tumor Virus RNA Biology Section, HIV Dynamics and Replication Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, to perform basic research on DNA tumor viruses (papillomavirus and Kaposi’s sarcoma-associated herpesvirus). This includes studies on genome structure, integration and expression, RNA splicing and post-transcriptional regulation of viral and host RNA transcripts, noncoding RNAs and nonsense-mediated RNA decay, and protein-RNA and RNA-RNA interactions in virus infection and tumorigenesis.

Application Deadline: Open Until Filled

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19. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Multiple post-doctoral positions are available with Dr. Lisa Boxer in the Laboratory of Genome Integrity to study chromatin regulation of neuronal development. The Boxer lab uses molecular and genomic approaches to study how mutations in chromatin regulators disrupt neuronal gene expression and lead to neurodevelopmental disorders and cancer.

Application Deadline: Open Until Filled

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20. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral position is available immediately in the laboratory of Dr. Deborah Morrison, which is affiliated with the Laboratory of Cell and Developmental Signaling, National Cancer Institute, National Institutes of Health. Dr. Morrison’s group takes a multidisciplinary approach to study the signal transduction pathway regulated by the RAS family of GTPases. In particular, Dr. Morrison’s work focuses on the RAF kinases, which are direct effectors of RAS, and on scaffold proteins that modulate RAS pathway signaling. 

Application Deadline: Open Until Filled

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21. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The postdoctoral fellow will focus on interrogating pericyte heterogeneity and plasticity in the metastatic microenvironment, following up on work published in our Nature Medicine 2017 article. The post-doctoral fellow will be trained in techniques related to cancer biology, vascular biology and computational analysis of gene expression, epigenetic, and microscopy datasets to further our understanding of the metastatic microenvironment in experimental models and patient data.

Application Deadline: Open Until Filled

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22. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Niethamer lab is seeking an engaged, motivated candidate whose research program will follow previous work defining the cellular composition of the pulmonary endothelium during lung development and in response to viral infection (doi: 10.7554/eLife.53072 and doi: 10.1126/science.abc3172) and identifying key factors expressed by endothelial cells and their essential role in lung regeneration (doi: 10.7554/eLife.83835). Potential projects will (1) expand our knowledge of how different lung endothelial cell fates are established, maintained, and regenerated after injury, (2) determine how endothelial cell signaling affects alveolar development and repair, and (3) define the role of different endothelial cell subtypes in lung alveolar morphogenesis during postnatal development or injury repair.

Application Deadline: Open Until Filled

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23. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our broad goal is to explore the molecular and cellular biology of thoracic cancers, namely mesothelioma and/or, thymoma, non-small cell lung carcinoma, etc. Currently, we have projects that involve (1) investigating microRNA-mRNA interactions in malignant mesothelioma, (2) novel local therapeutic delivery system(s) able to carry diverse types of payloads including nucleic acid, immunotherapeutics, targeted small molecule agents, or antibodies, (3) on the pathogenic signaling pathways relevant to tumor initiation, invasion, metastasis, and resistance, (4) constructing next-generation models of normal cells/tissues that can be used to model tumor development and processes as well as several other translational-based endeavors (e.g., developing novel tumor diagnostics and prognostics, etc.). 

Application Deadline: Open Until Filled

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24. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our group is applying high-throughput applied genomics methods, including single-cell RNAseq, single-cell TCR sequencing, DNA sequencing, CRISPR/Cas9, and bioinformatics combined with T-cell-based therapeutics to identify and develop novel immunotherapeutics for human cancers. We work with other investigators within the intramural program and industrial and pharmaceutical partners to rapidly translate our findings to the clinic.

Application Deadline: Open Until Filled

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25. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Eros Lazzerini Denchi, at the Laboratory of Genome Integrity within the Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), is seeking a highly motivated individual to join as a postdoctoral fellow. The successful candidate will engage in cutting-edge research using advanced cellular, molecular, and genomic tools to investigate the significance of telomere-associated proteins in cancer and age-related disorders. This is an exciting opportunity to work in a dynamic research environment at the forefront of telomere biology and DNA repair. The successful candidate will have access to state-of-the-art facilities, resources, and a collaborative network of scientists. 

Application Deadline: Open Until Filled

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26. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

One post-doctoral position is immediately available with Dr. Andre Nussenzweig in the Laboratory of Genome Integrity, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), to use computational methods in the study of mechanisms involved in DNA double-strand break repair and the roles of repair proteins in a variety of cancers that include leukemias and breast cancers, using mouse models. The position will emphasize efforts to understand gene regulation, chromatin, regulatory and structural variation and its relation to cancer. 

Application Deadline: Open Until Filled

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27. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

One post-doctoral position is immediately available with Dr. Andre Nussenzweig in the Laboratory of Genome Integrity, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH) to study the mechanisms involved in DNA double-strand break repair, with a focus on understanding the influence of chromatin structure on the maintenance of genome integrity and their roles in a variety of cancers using cutting-edge cellular, molecular, and genomic tools.

Application Deadline: Open Until Filled

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28. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A post-doctoral position in neuroscience is available in the lab of Dr. Chuan Wu, Experimental Immunology Branch, CCR, NCI in Bethesda, MD. The laboratory’s research interest focuses on how neuron-immune interactions regulate mucosal sensation for barrier integrity in health and disease. We seek to study how immune signaling participates in gut sensation and regulates gut-brain axis. We are also exploring new therapeutic approaches for patients with intestinal inflammation and related extraintestinal manifestations. We are utilizing interdisciplinary approaches to elucidate the crosstalk between the nervous system, microbial pathogens, and the immune system. 

Application Deadline: Open Until Filled

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