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26 Fully Funded PhD Programs at University of Cambridge, England

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Are you holding Master’s degree and looking for fully funded PhD positions? University of Cambridge, England invites online application for multiple funded PhD Programs / fully funded PhD positions in various research areas.

Candidates interested in fully funded PhD positions can check the details and may apply as soon as possible. Interested and eligible applicants may submit their online application for PhD programs via the University’s Online Application Portal. 

1. Fully Funded PhD Position in Unravelling piRNA-guided control of transposable elements

Summary of PhD Program:

This is an exciting opportunity for a talented student to join the interdisciplinary laboratory of Professor Greg Hannon located at the CRUK Cambridge Institute, University of Cambridge. The Hannon laboratory has broad interests ranging from discovery research to cancer biology. This studentship is embedded within a team of approximately ten scientists focused on RNA and chromatin biology. Work in the team covers a wide range of areas, including transcription, export, and processing of PIWI-interacting RNAs (piRNAs), as well as the establishment and maintenance of chromatin marks required for the silencing of transposable elements. This project aims to uncover the molecular mechanisms that underlie the piRNA pathway mainly using the fruit fly Drosophila melanogaster as a model.

Application Deadline: 13 November 2023

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2. Fully Funded PhD Position in Understanding Fibroblast Functional Heterogeneity in Pancreatic Cancer

Summary of PhD Program:

Cancer-associated fibroblasts (CAFs) have been shown to promote pancreatic cancer progression. Our laboratory and others have demonstrated that CAFs are characterised by different populations that can differentially contribute to tumour growth, metastasis formation, therapy response and immunosuppression. This research project will investigate the interplay between different CAF populations and malignant cells in pancreatic cancer with the goal to design combinatorial therapeutic approaches.

Application Deadline: 13 November 2023

Apply now

 

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3. Fully Funded PhD Position in genomic instability on the tumour microenvironment

Summary of PhD Program:

There is an opportunity for a talented student to join the interdisciplinary laboratory of Professor Greg Hannon located at the CRUK Cambridge Institute, University of Cambridge. The Hannon laboratory has a long-standing interest in RNA biology and cancer research, and a strong history of developing new tools to address cutting-edge questions in these fields. As part of the IMAXT Cancer Research UK Grand Challenge international collaboration, the lab has lead the way in spatial imaging of tumours and established a suite of technologies to interrogate tumour heterogeneity and the tumour microenvironment.

Application Deadline: 13 November 2023

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4. Fully Funded PhD Position in Synthetic Organic Chemistry and Chemical Biology

Summary of PhD Program:

We are looking for a highly motivated and enthusiastic individual capable of thinking and working independently. Applicants should have or shortly expect to obtain a first or upper second-class degree from a UK university, or an equivalent standard from an overseas university, in a relevant subject such as chemistry. Ideally, the candidate will have a strong background in organic chemistry. Practical experience of synthetic organic chemistry and peptide chemistry in a research environment would be beneficial.

Application Deadline: 1 December 2023

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5. Fully Funded PhD Position in therapeutic and climate change applications

Summary of PhD Program:

Our lab is particularly interested in studying the discovery, engineering, and development of super-enzymes. We are currently developing technology that allows the screening and computational interpretation of combinatorial complete libraries of mutant protein variants. We are now in a position to further develop and deploy these technologies to supercharge virtually any natural biochemical reaction in applications ranging from signaling and therapeutics to carbon capture and climate change. By benefitting from these novel technologies and initially identifying the best natural proteins for a given biochemical reaction, in this project we will be able to deeply screen for novel super-enzymes that enable new biological functionalities, and effectively exceed the functional properties of these natural enzymes.

Application Deadline: 13 November 2023

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6. Fully Funded PhD Position in breast cancer treatment response

Summary of PhD Program:

Breast cancer patients show highly variable responses to different treatments. Some respond durably, while others start by responding but eventually relapse and a subset show little evidence of response at all. The biological basis of these differences remains obscure but the spatial architecture of tumours is likely a major contributor. Novel technologies for multiplexed molecular measurements of tumour tissues that preserve spatial relationships offer the opportunity to precisely dissect the contribution of the spatially resolved multicellular tumour ecosystem as a response driver. To take full advantage of multiplexed spatial measurements, however, we must devise efficient computational tools to parse and integrate these data across assays. We are collating a large and unique collection of multi-modal spatial data from hundreds of breast cancer patients enrolled in neoadjuvant immunotherapy trials.

Application Deadline: 13 November 2023

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7. Fully Funded PhD Position in Leveraging innate lymphoid cells to improve cancer therapy

Summary of PhD Program:

Conventional cancer treatments, including radiation- and chemo-therapy, are capable of stimulating the immune response to cancer cells. Understanding how anti-tumour immune responses are locally triggered permits the design of better therapeutic strategies. We focus on a novel immune cell-type called the ‘Group 2 Innate Lymphoid Cell’ or ILC2, which is emerging as a critical link between innate and adaptive immunity. This PhD project specifically focusses on revealing both fundamental immunology about how ILC2 interact with adaptive anti-tumour immune cells, and subsequently aims to therapeutically exploit these findings in models of solid tumours.

Application Deadline: 13 November 2023

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8. Fully Funded PhD Position in Epigenetic Features of the Genome

Summary of PhD Program:

The lab exploits both chemistry and biology to address fundamental mechanisms of genome function. While many genetic determinants of cancer are known, alternative nucleic acid secondary structures and chemically modified DNA (or RNA) bases can be epigenetic features of nucleic acids that are important to normal biology and in oncogenesis. The project will explore chemical modifications as epigenetic features and how these influence secondary structure formation and function in the genome of normal and cancer cells. The scope of the project may include exploring the formation and dynamics of G-quadruplex structures as well as modified DNA bases in the genome and their roles in gene 3D chromatin structure, gene expression, DNA replication and genome stability.

Application Deadline: 13 November 2023

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9. Fully Funded PhD Position in Delineating small RNA-mediated chromatin silencing

Summary of PhD Program:

We are looking for a talented and motivated student to join our interdisciplinary team in Professor Greg Hannon’s lab located at the CRUK Cambridge Institute (part of the University of Cambridge) to investigate the molecular mechanisms of small RNA-mediated chromatin silencing. As a whole, the Hannon laboratory has broad interests that range from discovery research to cancer biology, as well as a strong commitment of developing and using new tools to address cutting-edge questions in these fields.

Application Deadline: 13 November 2023

Apply now


10.
Fully Funded PhD Position in Defining the role of FOXA1 and functional residues in pancreatic cancer

Summary of PhD Program:

Pancreatic Ductal Adenocarcinoma (PDAC) is a deadly disease with one of the worst survival rates, due to the lack of treatment options or clinical advances. Recent evidence has suggested that the pioneer transcription factor FOXA1 gets co-opted in PDAC to drive metastasis in the advanced disease setting. We have validated this initial finding and have provided insight into the role of FOXA1 in this disease, where we have found that it does not contribute to primary tumour growth, but instead becomes a driver specifically in metastasis. Given the important role of FOXA1 in PDAC metastasis, we aim to characterise its function in this disease context. We have generated a number of resources and reagents that allow us to identify specific residues on FOXA1 that are important for its function and to potentially discover FOXA1-associated proteins that contribute to metastasis.

Application Deadline: 13 November 2023

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11. Fully Funded PhD Position in Chemical Biology of the Genome and the Epigenome

Summary of PhD Program:

The first area is the investigation of the structure and function of DNA (and RNA) secondary structures called G-quadruplexes. Studies both in vitro and in cells suggest G-quadruplexes may be important for the control of transcription, translation and other key processes in biology. We employ cutting edge technologies in chemical biology, molecular biophysics, structural biology, cell biology and genomics to explore mechanisms involving G-quadruplexes, with an emphasis on intervention strategies for cancer [e.g. see Nature Biotechnology 2023; Nature Chemistry 2021, 13, 626-633; Trends in Chemistry, 2020, 2:2, 123-136; Nature, 2018, 558, 465].

Application Deadline: 14 November 2023

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12. Fully Funded PhD Position in Characterisation of metastatic events in estrogen receptor positive breast cancer

Summary of PhD Program:

Estrogen Receptor positive (ER+) breast cancer comprises 75% of all breast cancer cases. ER is a transcription factor that is known to turn on the genes that cause cell division and cancer progression. ER activity is dictated by a pioneer factor called FOXA1, which can associate with compacted DNA, creating the enhancer elements that will subsequently recruit ER to switch on adjacent genes. ER and FOXA1 are known to be mutated in metastases that arise from ER+ breast cancer, but there is a spectrum of additional mutational events that are observed in ER+ metastasis. This project will explore the role of the metastasis-specific mutations and will focus on the detailed molecular characterisation of mutational events that are consistently observed in clinical samples.

Application Deadline: 13 November 2023

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13. Fully Funded PhD Position in Role of Metabolic Disease in Alzheimers Disease

Summary of PhD Program:

The proposed project will clarify how metabolic disease mechanistically contributes to neurodegenerative disease by revealing: (a) how diet alters protein aggregation and the development of Alzheimer’s Disease (AD), (b) which tissues are most susceptible, and, (c) which proteins show the most aggregation. The project fits into the theme of multimorbidity and organ-organ interactions. The associated technologies may help enable early diagnosis, giving at-risk individuals more time to make lifestyle changes to potentially reduce their risk and adjust to living with dementia.

Application Deadline: 30 November 2023

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14. Fully Funded PhD Position in Hearable Systems

Summary of PhD Program:

A fully funded 3 years (overseas or home) PhD Studentship is provided through a donation from Nokia Bell Labs to work in the general area of hearable devices and systems under the supervision of Prof Cecilia Mascolo. The project will focus on understanding the potential and applications of devices worn around the ear for the purpose of fitness and health tracking. The specific aim of the studentship can range from systems contribution to efficient devices (given the form factor) to the novel exploration of the sensing capabilities of devices as well as the algorithmic innovation related to improving healthcare and fitness tracking through such devices.

Application Deadline: 4 December 2023

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15. Fully Funded PhD Position in Haematological Malignancies

Summary of PhD Program:

Cambridge is one of the best places in the world to study haematological malignancies. We have the largest concentration of researchers working on haematological malignancies in Europe, with seventeen research groups based around the city making us a globally significant centre for research in leukaemia, lymphoma and pre-leukaemic conditions. World leading PIs based in Cambridge include Peter Campbell, Bertie Göttgens, Tony Green, Brian Huntly, Nicole Soranzo, George Vassiliou and Alan Warren. The Department of Haematology has an exceptional record in training young researchers. Over thirty students who studied for their PhDs in the Department have become PIs, either in Cambridge or elsewhere.

Application Deadline: 19 November 2023

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16. Fully Funded PhD Position in Learning from and outperforming nature

Summary of PhD Program:

In our lab we are resolving how and when signaling systems evolved using in silico reconstruction and high-throughput biochemical characterization of ancestral proteins, the main goal of this project. Since some of the signaling systems that we study have emerged multiple times, our lab is in a unique position to address a fundamental question in protein biochemistry and evolution; whether the evolution of a new molecular function is dictated by biophysical constraints, contingent on a particular evolutionary history, or just one of many possibilities that could have arisen. In addressing these questions, we will also be able to analyze and quantify the degree to which we can engineer synthetic proteins whose function supersedes the ones from extant and ancestral natural ones.

Application Deadline: 13 November 2023

Apply now

 

17. Fully Funded PhD Position in Drugging the undruggable

Summary of PhD Program:

Our laboratory has recently made exciting progress in disentangling pro- and anti-oncogenic signaling driving cancer and in screening targets with combinatorial complete peptide libraries. In this project, we will be capitalizing on these advances to: First, develop our peptide screen technology further, so that we can move towards the incorporation of small molecule fragments to screen and target resistance variants of EGFR and other kinases in brain cancer, lung cancer and leukemia. Second, identify critical vulnerabilities downstream of pro- and anti-oncogenic signaling in brain cancer, lung cancer and leukemia; and third, expand our ability to screen targets beyond protein kinases, such as Rb, Myc, Ras, Histone H3, other transcription factors, epigenetic regulators and signaling related proteins along the MAPK pathway or more generally relevant to these processes.

Application Deadline: 13 November 2023

Apply now

 

18. Fully Funded PhD Position in Health Professionals

Summary of PhD Program:

The Universities of Cambridge and East Anglia, together with the Wellcome Sanger Institute, invite applications for up to 7 fellowships in the PhD Programme for Health Professionals, to be taken up by the end of 2024. The fellowships provide funding for clinical salary, University Composition Fees and research consumables for 3 years. Prior to commencement, the Programme can provide up to three months of additional salary support, enabling successful applicants to experience research in different groups, before making an informed choice of project and supervisor.

Application Deadline: 2 November 2023

Apply now

 

19. Fully Funded PhD Position in Cancer Biology

Summary of PhD Program:

Cancer Research UK (CRUK) Cambridge Centre has a fully-funded innovative MRes + PhD programme, designed to give postgraduate students a broad understanding of both the basic biology and the clinical management of the whole spectrum of cancer. This course also allows students to develop their own skills in experimental science as well as in project design and management.

Application Deadline: 15 November 2023

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20. Fully Funded PhD Position in Cancer MRes

Summary of PhD Program:

The CRUK Cambridge Centre is a dynamic collaboration of academic researchers, clinicians, and the pharmaceutical and biotech industries based in the Cambridge area. By being part of the Centre, students will have the opportunity to attend a number of lecture series, workshops and meetings aimed at facilitating and strengthening collaborations between complimentary disciplines and across different departments and institutes.

Application Deadline: 15 November 2023

Apply now

 

21. Fully Funded PhD Position in Non clinical 

Summary of PhD Program:

Visceral pain affects millions of people worldwide, poses a significant economic burden, and affects the most intimate activities of daily living. Treatment for chronic pain is inadequate due to inefficacy and/or drug side effects, a problem that is particularly acute in visceral pain because many commonly used drugs have gastrointestinal side effects. There is growing evidence for the role of the gut microbiome in the modulation of visceral pain, via both direct effects of microbial mediators on sensory neurons and indirect effects via immune cell activation. The aim of this project will be to investigate the cellular mechanisms by which human gut microbes modulate visceral pain using functional recordings from pain sensing neurons, nerves and in vivo behavioural experiments in models of visceral pain.

Application Deadline: 31 October 2023

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22. Fully Funded PhD Position in Multimodal AI-guided tools for early prediction of disease progression in neurodegenerative disorders

Summary of PhD Program:

The project focuses on the development and implementation of AI-guided approaches for early prediction of neurodegenerative disorders. In particular, we aim to develop an innovative data-driven approach that capitalises on state-of-the-art algorithms from artificial intelligence (foundational models) to mine multimodal data from polygenic risk scores, MRI scans, biomarkers and cognitive tasks for early prediction of disease progression. Using this cross-disciplinary approach, we will develop AI-guided tools that predict individualised disease trajectories. We will optimise and validate these tools using large-scale research data and real-world data from clinical trials to assess their efficacy in identifying the right patients for the right treatment.

Application Deadline: 20 November 2023

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23. Fully Funded PhD Position in Reading and Writing in Medieval Womens Religious Communities

Summary of PhD Program:

This PhD studentship offers an opportunity to investigate the culture of female religious communities in the Middle Ages, through a study of their surviving manuscripts. We are inviting applicants to propose a project that explores any aspect of women’s conventual life, with the specific aim of bringing together kinds of sources that have rarely been discussed in combination. The themes and structure of the project are entirely open, provided the proposal is interdisciplinary and combines different types of manuscripts in novel, creative, and productive ways.

Application Deadline: 4 January 2024

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24. Fully Funded PhD Position in Philosophy of Wellbeing Policy

Summary of PhD Program:

The PhD studentship aims at making explicit the knowledge that exists among practitioners and in the less visible space of implementation of well-being policies and exploring its relevance for evidence-based policy. Using review of a variety of literatures as well as interviews with the staff of What Works Centre Wellbeing and cognate practitioners, this project seeks to reconstruct the methodology behind generation and deployment of wellbeing evidence as it travels between the academy and the practitioners. In addition to being a contribution to wellbeing practice, such a project trials an innovative approach to philosophy of science and applied epistemology more generally.

Application Deadline: 5 December 2023

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25. Fully Funded PhD Position in Non-Normative Identities in 20th-21st Century Catalan Cultures

Summary of PhD Program:

The PhD student will carry out original research that addresses the presence of minoritarian/non-normative identities within Catalan cultures. The project will need to address the complexities of subaltern expressions of gender, sexuality, race, ethnicity, ability, migration, and/or class situated in the framework of Catalan cultures, perhaps exploring the nuanced intertwining of identities and nationhood. Applicants will be asked to propose their own PhD research project, based on their qualifications and interests that fits within the general parameters specified.

Application Deadline: 5 December 2023

Apply now

 

26. Fully Funded PhD Position in Multilingual teaching, learning and assessment of English in India’s primary schools

Summary of PhD Program:

The PhD student will carry out original research addressing an important gap in recognizing and destigmatizing the use of multiple languages in the classrooms of linguistically diverse societies of the Global South. While multilingualism is the norm in these contexts, there is a need to develop and test the effectiveness of multilingual educational materials for language learning, use and assessment.

Application Deadline: 5 December 2023

Apply now


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