VIB Leuven, Belgium invites multiple online application for Postdoctoral Positions in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.
1. Postdoctoral Positions in Bioinformatician in Spatial Biology
Summary of Postdoctoral Fellowships:
The current position at VIB is intended to run spatial biology bio-informatics services in close collaboration with KU Leuven and the European Spatial Biology Center (ESBC NV). The ESBC has recently kick-started as a service provider for spatial biology technologies at scale, by offering services to large-scale projects and providing key biological insights to its customers. To strengthen the spatial biology services in Leuven, VIB wishes to recruit an enthusiastic and energetic bioinformatician in Spatial Biology. In this role, you will be managing and critically analysing large spatial biology data sets to generate novel biological insights and develop new analysis tools when needed, mostly for industrial (and academic) clients.
Application Deadline: Open Until Filled
2. Postdoctoral scientist
Summary of Postdoctoral Fellowships:
The lab of Prof. Alsafar has a strong focus on the identification of genetic risk factors in diabetes, oncology, and vascular diseases. The research of Prof. Peter Carmeliet focuses on the development of blood vessels (angiogenesis) and vascular heterogeneity in health and disease, with the aim to identify novel therapeutic pro- and anti-angiogenic strategies. In diabetes, a key unmet medical need is to develop cures for the life-threatening medical (cardiovascular) complications. The discovery of new molecular insights and treatments for diabetic cardiovascular complications is highly relevant for the UAE, where diabetes is endemic (ca 44%). In this collaborative project, we will use a novel artificial intelligence (AI)-based target discovery tool to discover ’mystery’ genes and a validation approach based on the lipid nanoparticle (LNP)-RNA technology to manipulate the expression of selected mystery genes.
Application Deadline: Open Until Filled
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3. Postdoctoral Researcher to participate in cutting-edge cancer research projects
Summary of Postdoctoral Fellowships:
The Laboratory for Mechanisms of Cell Transformation, headed by Professor Anna Sablina, is a pioneer in the investigation of cooperative interactions promoting human disease. To achieve this, we have taken a multi-faceted approach by combining mouse modelling with comprehensive CRISPR-based techniques and multi-omics approaches. The results of our studies have been published in multiple high-profile journals including Science, Cancer Cell, and Nature Cell Biology. Our current research is aimed to decipher the proteostatic regulation of the RAS GTPases and their relevance to human health and disease. Our final goal is to identify specific therapeutic targets regulating RAS biology, that could be drugged for personalized therapy in cancer patients.
Application Deadline: Open Until Filled
4. Postdoctoral Positions in Bio-Informatics
Summary of Postdoctoral Fellowships:
The MetaNiche team is looking for a highly motivated and skilled computational scientist/ bioinformatician to join our efforts in understanding the spatio-temporal cellular and molecular changes during lymph node metastases. The MetaNiche team is part of the VIB-KU Leuven Center for Cancer Biology (CCB), an interdisciplinary research institute of the VIB with excellent facilities and leading research groups in e.g., oncology, genetics/-omics, molecular biology and translational research, located at Campus Gasthuisberg, Leuven.
Application Deadline: Open Until Filled
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5. Postdoctoral Positions in Angiogenesis and Vascular Metabolism
Summary of Postdoctoral Fellowships:
The research of Prof. Peter Carmeliet focuses on the development of blood vessels (angiogenesis) and vascular heterogeneity in health and disease, with the aim to identify novel therapeutic pro- and anti-angiogenic strategies. Current anti-angiogenesis therapies (AATs), by targeting the pro-angiogenic factor VEGF, suffer resistance and insufficient efficacy. The Carmeliet lab explores opportunities to overcome these limitations and to improve AAT by focusing on endothelial cell metabolism, endothelial heterogeneity and in particular, endothelial immunity. Recent projects, combining single-cell transcriptomics with bulk multi-omics (transcriptomics, (epi)-genomics, proteomics & metabolomics) revealed novel insights in endothelial cell metabolism and heterogeneity in health and disease that can help design novel AAT strategies.
Application Deadline: Open Until Filled
6. Postdoctoral Positions in Angiogenesis and Vascular Heterogeneity
Summary of Postdoctoral Fellowships:
The laboratory of Professor Peter Carmeliet is part of the Center for Cancer Biology (CCB), one of the research departments of VIB (Flanders Institute for Biotechnology) located at the KU Leuven, Leuven, Belgium. The lab is focusing on unraveling the molecular and cellular basis of the formation of blood vessels (angiogenesis) in health and disease, and in particular the role of vascular metabolism and vascular heterogeneity herein, with the ultimate goal to identify novel therapeutic pro- or anti-angiogenic strategies.
Application Deadline: Open Until Filled
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7. Postdoc / Project manager position
Summary of Postdoctoral Fellowships:
The lab of Prof. Carmeliet, the Laboratory of Angiogenesis and Vascular Metabolism, is part of the Center for Cancer Biology (CCB), one of the research departments of VIB (Flanders Institute for Biotechnology) located at the KU Leuven, Leuven. The lab is focusing on unraveling the molecular and cellular basis of blood vessel formation (angiogenesis) and on the function and dysfunction of the vascular endothelium in health and disease. Recent projects, combining single-cell transcriptomics with bulk multi-omics (transcriptomics, (epi)-genomics, proteomics & metabolomics) revealed novel insights in endothelial cell metabolism and heterogeneity in health and disease, including contribution of the endothelium in immune responses.
Application Deadline: Open Until Filled
8. Postdoctoral Positions in multiplex genome engineering of the maize yield related genes
Summary of Postdoctoral Fellowships:
Feeding the growing world population under changing climate conditions poses an unprecedented challenge on global agriculture and our current pace to breed new high-yielding crop varieties is too low to face the imminent threats to food security. The ERC project BREEDIT, aims for an expeditious evaluation of combinations of potential yield contributing alleles by unifying ‘classical’ breeding with gene-centric molecular biology. The acronym BREEDIT, a word fusion of breeding and editing, reflects the basic concept of combining breeding with multiplex genome editing of yield and growth-related genes. By introducing plants with distinct combinations of genome-edited mutations in more than 60 known yield-related genes into a crossing scheme, the combinatorial effect of these mutations on plant growth and yield will be evaluated.
Application Deadline: Open Until Filled
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9. Postdoctoral Positions in Study of Drosophila Sleep
Summary of Postdoctoral Fellowships:
The Laboratory of Sleep and Synaptic Plasticity (PI: Sha Liu) at the VIB-KU Leuven Center for Brain & Disease Research is seeking a postdoctoral researcher to join our group. Our lab employs multi-disciplinary approaches, including Drosophila genetics, quantitative behavior analysis, electrophysiology, in vivo functional imaging, and neural circuit mapping and manipulation, to study the basic mechanisms underlying sleep and its function in the brain at synaptic and circuit levels.
Application Deadline: Open Until Filled
10. Postdoctoral position to investigate the role of TRP channels in brain disorders
Summary of Postdoctoral Fellowships:
For a translational, industry-funded project lead by Dr. Joris Vriens and Dr. Thomas Voets, we are currently seeking for a talented postdoctoral researcher to investigate the role of TRP channels in brain disorders. Using a combination of state-of-the-art in vitro and in vivo approaches, the postdoctoral researcher will examine how inherited and acquired gain-of-function of neuronal TRP channels can cause epilepsy and neurodevelopmental disorders, and contribute to the development of novel pharmacotherapies to treat these disorders.
Application Deadline: Open Until Filled
11. Postdoctoral Positions in Bioinformatics, Neuroscience and Drug Discovery
Summary of Postdoctoral Fellowships:
The Laboratory for the Research of Neurodegenerative Diseases headed by prof. Bart De Strooper is a vibrant environment where key issues related to Alzheimer’s disease are tackled. We are currently looking for a highly skilled and motivated postdoc to join our multidisciplinary project on the cellular response to Alzheimer’s pathology (De Strooper and Karran, Cell, 2016). In this project we will investigate why some people remain protected against Alzheimer’s Disease despite the presence of amyloid plaques. Understanding why some people are resilient to Alzheimer’s disease will help us to identify new drug targets.
Application Deadline: Open Until Filled
12. Postdoctoral Positions in (deep) learning the genomic regulatory code
Summary of Postdoctoral Fellowships:
The Laboratory of Computational Biology (Stein Aerts lab) at VIB-KU Leuven is seeking a postdoc to join our efforts in deciphering the genomic regulatory code underlying cellular identity, with a focus on the brain. You will develop new AI strategies to learn the genome syntax using large-scale single-cell multi-ome atlases as training data. You will unravel the diversity of neuronal cell types in the brain of various species (octopus, birds, mammals) through machine-learning & comparative genomics.
Application Deadline: Open Until Filled
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13. Postdoctoral Positions in Computational methods in neurodegeneration research
Summary of Postdoctoral Fellowships:
The goal of this project is to define and study the molecular drivers of synaptic remodeling during cycles of hibernation. The goal is to combine new single-cell and spatial omics technologies in hamster brains with bioinformatics and machine learning and then compare the changes in hibernation to alterations in dementia in human brains. The ultimate gain is that you will uncover mechanisms of a remarkable process of synaptic resilience (in hibernating animals) and define if these are directly relevant to mechanisms of dementia and neurodegeneration.
Application Deadline: Open Until Filled
14. Postdoctoral Positions in synthetic ecology of the human gut microbiota
Summary of Postdoctoral Fellowships:
The lab of Jeroen Raes (VIB, KU Leuven) is home to an enthusiastic, diverse and international group of researchers in the field of gut microbial ecology and its clinical applications. Beyond our expertise in metagenomic analysis using our in-house bioinformatics expertise the lab has in recent years invested anaerobic microbiology of colon bacteria in order to study their physiology and interactions. To support us in this effort we are currently looking for a postdoctoral researcher for our high-throughput anaerobic fermentation unit.
Application Deadline: Open Until Filled
15. Postdoctoral Positions in Study of Neuronal Basis in Motor Control
Summary of Postdoctoral Fellowships:
The Takeoka lab studies how animals generate and control motor behavior in health and disease, using a multi-disciplinary approach including detailed motor kinematic assessments, mouse genetics, optogenetic, pharmacogenetic, electrophysiological, and imaging techniques. The lab investigates how different types of sensory feedback circuits control repetitive and complex motor behavior, with a primary focus on somatosensory and visual feedback.
Application Deadline: Open Until Filled
16. Postdoc position to study neural circuits of visual tracking
Summary of Postdoctoral Fellowships:
We seek a talented and creative postdoctoral scholar to study neural circuits of vision with focus on motion processing and visuomotor behaviour in mice using state-of-the-art methods. The project builds on large a large array of functional cellular imaging and connectivity data that were acquired in mouse cortical and thalamic visual pathways (Han et al 2020). The goal is to delineate cortical and subcortical circuits responsible for encoding and tracking of visual objects. The project will involve advanced behavioral assays, patterned light optogenetics and large-scale recordings.
Application Deadline: Open Until Filled
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17. Postdoctoral Positions in Molecular Signal Transduction in Inflammation
Summary of Postdoctoral Fellowships:
The UMSTI (https://www.irc.ugent.be/rbe) studies the molecular and cellular mechanisms that control inflammation and immunity. In the frame of the EOS (Excellence of Science) funding programme we have recently initiated the BRIDGE project (Taking IBD Genes from GWAS to Function to Drug Target). BRIDGE brings together scientists from 4 different Belgian universities and 1 US lab with complementary expertise in genomics, immunology, cell biology, and clinical gastroenterology to jointly develop a pipeline to systematically interrogate IBD-relevant functions of GWAS-identified candidate genes relevant to disease activation and recurrence.
Application Deadline: Open Until Filled
18. Postdoctoral Positions in Autophagy in inflammation and inflammatory disorders
Summary of Postdoctoral Fellowships:
The research team of Prof. Mathieu JM Bertrand has a vacancy for a highly motivated postdoctoral scientist with research experience in autophagy, cell death, and/or inflammation. The successful candidate will be responsible for studying mechanisms of autophagic degradation and its interplay with inflammation and cell death modalities, using cells of human and murine origin and mouse models of inflammatory diseases. This research is part of the iBOF ATLANTIS project (Autophagy in inflammation and inflammatory disorders, from basic insights to experimental therapy). ATLANTIS brings together scientists with complementary expertise in the fields of autophagy, cell death, inflammation, angiogenesis, and drug screening/medicinal chemistry.
Application Deadline: Open Until Filled
19. Postdoctoral Positions in biochemistry and biophysics
Summary of Postdoctoral Fellowships:
Due to the development of resistance to antibiotics, bacterial infections are becoming more life-threatening every year. In addition to resistance, bacterial persistence offers an important means to avoid clearance of infections. Persisters are formed by phenotypic switching to an antibiotic-tolerant state, rendering a small subset of cells within an isogenic population capable of surviving antibiotic treatment. Within this ongoing research project we want to gain more insight into the mechanisms of persistence by unravelling the associated molecular pathways down to atomic resolution (e.g. Verstraeten et al. Mol. Cell 2015; Gkekas et al. J. Biol. Chem. 2017; Verstraeten et al. Mol. Microbiol. 2019). The project is part of an interdisciplinary Excellence of Science program in collaboration with the teams of Jan Michiels, Régis Hallez, Françoise Van Bambeke, Steven Ballet and Jörg Vogel.
Application Deadline: Open Until Filled
20. Postdoctoral Positions in the molecular studies of bacterial functional amyloids
Summary of Postdoctoral Fellowships:
A fully funded Postdoc position is available in the lab Structural & Molecular Microbiology at VIB – Vrije Universiteit Brussel, Belgium, to work on an FWO project studying the nucleation, cross-reactivity, and structure of bacterial functional amyloids (FA). Amyloids are aggregative protein or peptide fibrils best known for their implication in a range of neurodegenerative illnesses. The self-assembly into cross-ß-structured fibrils is however not restricted to the off-pathway protein misfolding events, but also found as the native conformation of a wide range of pro- and eukaryotic proteins referred to as FA. FAs produced by prokaryotes are often related to the persistence and virulence of bacterial biofilms. Despite their importance, little is known regarding the FA ultrastructure and their mechanism of formation.
Application Deadline: Open Until Filled
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21. Postdoctoral Positions in Computational genomics of Alzheimer’s disease
Summary of Postdoctoral Fellowships:
The Sleegers lab (Complex Genetics of Alzheimer’s Disease) at the VIB-UAntwerp Center for Molecular Neurology, Belgium, is seeking a highly motivated postdoctoral fellow to work in the field of computational genomics of complex Alzheimer’s disease. The Sleegers lab is committed to increasing insights into the complex genetics of Alzheimer’s disease and to investigating the translational potential of genetic discovery. We use advanced genomic technologies and genetic-epidemiological methods on human study populations to identify molecular mechanisms that can serve as future targets for early detection, prevention, and treatment. We participate in numerous international networks and consortia, to enhance gene identification, interdisciplinary gene characterization and early biomarker discovery.
Application Deadline: Open Until Filled
22. Postdoctoral Positions in Computational Neurobiology Lab
Summary of Postdoctoral Fellowships:
We are the Computational Neurobiology lab and address fundamental questions in chromatin organization, epigenetics, and brain biology. We develop machine learning approaches for large-scale data integration and reconstruct cis-regulatory networks to understand how a cell “chooses” its fate. In particular, we focus on the role of chromatin organization in neuronal cell fate specification and neurodegenerative disease, aiming to bring the results of fundamental research to the clinic. The project aims to understand the mechanisms underlying neuro-immune crosstalk in AD development and progression. To this end, the successful candidate will integrate large single-cell and bulk datasets across multiple data modalities into cis-regulatory networks, with a particular focus on chromatin organisation.
Application Deadline: Open Until Filled
23. Postdoctoral Positions in in cancer immunology and the tumor immune microenvironment
Summary of Postdoctoral Fellowships:
The Jo Van Ginderachter (JVG) lab is looking for an outstanding postdoctoral scientist interested in understanding how the heterogeneity and pro-tumoral activity of tumor-associated macrophages is regulated and how the manipulation of such regulatory mechanisms can be harnessed to improve immunotherapy. We are especially interested in understanding how RNA epigenetic alterations sculpt tumor-associated macrophages and affect the tumor-promoting function of these cells in various mouse models of non-small cell lung carcinoma and triple-negative breast cancer, as well as their human counterparts.
Application Deadline: Open Until Filled
24. Postdoctoral Positions in clinical development dendritic cell therapy as cancer treatment
Summary of Postdoctoral Fellowships:
The Laouimmunology lab headed by prof. Damya Laoui is an integral part of the laboratory of Myeloid Cell Immunology (vib.be/labs/van-ginderachter-lab and cmim.research.vub.be). It is located in Brussels at the VUB campus Etterbeek and is both part of the VIB Inflammation Research Center (IRC) and Vrije Universiteit Brussel (VUB). The Laouimmunology lab is focused on unravelling the role of conventional dendritic cells (cDCs) in the tumor microenvironment and how cDCs can be used to prevent tumor growth and metastasis. We have shown that tumor-derived cDCs, when isolated from the tumor and re-injected in mice, can reduce tumor growth significantly (Laoui et al. Nature Communications, 2016).
Application Deadline: Open Until Filled
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25. Postdoctoral Positions in Cancer Immunology and Lipid Metabolism in the Tumor Immune Microenvironment
Summary of Postdoctoral Fellowships:
The Jo Van Ginderachter lab is looking for an excellent postdoctoral scientist interested in understanding the mechanisms that regulate the heterogeneity and pro-tumoral activity of tumor-associated macrophages, and how we can use such mechanisms to optimize immunotherapy. In particular, we want to understand how lipids and altered lipid metabolism regulate tumor-associated macrophages and whether we can reprogram the macrophages by interfering with lipid metabolism.
Application Deadline: Open Until Filled
