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24 Postdoctoral Fellowships at St. Jude Children’s Research Hospital, Tennessee

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Are you holding PhD degree and looking for Postdoctoral Fellowships? St. Jude Children’s Research Hospital, Tennessee invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.

1. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The laboratory of Dr. Asuncion Mejias in Infectious Diseases is seeking a highly motivated individual to study viral respiratory infections in pediatric populations. Respiratory tract infections are the leading cause of infant mortality worldwide, and viral respiratory tract infections caused by RSV are the leading cause of respiratory tract infections in pediatric populations. The Mejias lab utilizes large clinical data sets and molecular analysis of patient samples to define the causes and responses of severe respiratory tract infections with a focus on RSV and other common childhood viral pathogens. 

Application Deadline: Open Until Filled

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2. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Mittag laboratory invites applications for a Postdoctoral Research Fellow to work on structures of the tumor suppressor and ubiquitin ligase component SPOP. We have recently solved the first cryo-EM structures of full-length SPOP (Cuneo et al. Mol Cell 2023), and they have revealed interfaces that had not recently been observed in structures of smaller constructs. Importantly, these interfaces are lined with cancer mutations whose molecular mechanisms were not previously understood, but now provide molecular explanations for pathophysiological mechanisms. We have also revealed that certain mutations lead to large changes in quaternary assembly. 

Application Deadline: Open Until Filled

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3. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Several postdoctoral positions are available in the laboratory of Dr. Victor J. Torres in the new Department of Host-Microbe Interactions at St. Jude Children’s Research Hospital. The Torres lab is interested in dissecting the complex interactions between pathogenic bacteria and the mammalian host. Currently, the lab is focusing on antibiotic resistant (AMR) bacteria, which have been recognized by the World Health Organization as a serious threat to human health. We take advantage of multidisciplinary approaches and combine techniques from bacteriology, genetics, molecular biology, biochemistry, structural biology, cellular biology, and immunology with primary tissue culture models and a variety of murine models of infection, to address our favorite questions.

Application Deadline: Open Until Filled

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4. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Rosch lab is looking for a postdoctoral scientist with an interest in host-pathogen interactions and/or antibiotic resistance. We are I looking for candidate with a PhD in Microbiology, Molecular Biology, or related field. Ideal candidates will have proven expertise in bacterial genetics, molecular techniques, and/or pathogenesis studies and excellent communication skills. Individuals should have the ability to work collaboratively in a fast-paced research environment. Research will focus on understanding the genetic basis of antibiotic resistance in Streptococcus pneumoniae as well as mechanistic studies of virulence.

Application Deadline: Open Until Filled

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5. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral position is available at St. Jude Children’s Research Hospital for an outstanding and highly motivated candidate to investigate the innate immune responses against infection. 

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6. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Tsai Laboratory is seeking dynamic and creative candidates for a fully supported postdoctoral fellowship on genome editing technologies for therapeutic treatment of genetic disorders. CRISPR genome editors, adapted from bacterial adaptive immune systems, are transforming both basic biological research and genomic medicine. At St. Jude, we are working toward advancing these technologies towards patient treatments for sickle cell disease and bone marrow failure disorders.

Application Deadline: Open Until Filled

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7. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral researcher position is available in Dr. Yong Feng’s laboratory at the Department of Immunology in St. Jude Children’s Research Hospital (www.stjude.org/feng). Research in Dr. Feng’s laboratory is utilizing innovative approaches and cutting-edge technologies to decipher the mechanisms governing T cell tolerance involved in autoimmunity and anti-tumor immune response. Highly self-motivated candidates with recently granted Ph.D. or equivalent in immunology, genetics, molecular biology, cell or developmental biology are invited to apply. 

Application Deadline: Open Until Filled

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8. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Chen Lab studies: i) Chemical modulation of transcription; ii) Signal crosstalk among transcription factors; and iii) Selective inhibition of highly homologous enzymes. We take a hypothesis-driven and technology-enabled multidisciplinary approach to develop chemical probes and investigate biological mechanisms. Particularly we use the promiscuous xenobiotic nuclear receptors (PXR and CAR) as models to investigate the transcription networks that regulate therapeutic responses. PXR and CAR regulate the detoxification system (e.g., by transcriptionally controlling CYP3A4 and CYP3A5—drug-metabolizing enzymes that metabolize more than 50% of clinical drugs), the dysregulation of which contributes to drug toxicity and drug resistance. 

Application Deadline: Open Until Filled

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9. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Obeng Laboratory is seeking creative and highly motivated candidates for a fully supported postdoctoral fellowship studying the pathogenesis of myeloid malignancies. The major interests of the lab are determining how acquired mutations in hematopoietic stem cells lead to the development of clonal hematopoiesis, myelodysplastic syndrome, and leukemia, in addition to identifying and studying novel treatments that selectively target malignant clones.

Application Deadline: Open Until Filled

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10. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral position is available in the Derecka Lab in the Department of Hematology at St. Jude Children’s Research Hospital to study transcriptional regulation of the bone marrow niche. The major research goal of our group is to gain mechanistic insights into cellular cross communication between bone marrow microenvironment and hematopoietic compartment, in steady state and pathophysiological conditions. You will have the opportunity to develop new exciting projects involving changes of bone marrow microenvironment and its impact on aging blood system; transcriptional dysregulation of bone marrow niche in hematological disorders and bone marrow niche-induced changes of chromatin landscape in hematopoietic progenitors. 

Application Deadline: Open Until Filled

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11. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are excited to announce a postdoctoral fellowship available in the laboratory of Dr. Charles Roberts in the Division of Molecular Oncology at St. Jude Children’s Research Hospital in Memphis, TN. Dr. Roberts is a leader in the field of cancer epigenetics, and his research has provided new insights into the central role of chromatin remodeling perturbations in cancer, discoveries that have been translated into investigational therapies for both pediatric and adult cancer patients. His research specifically focuses on SWI/SNF (BAF) chromatin remodeling complexes. Perturbation of these complexes has broad relevance to cancer as at least nine genes that encode SWI/SNF subunits are collectively mutated in over 20% of all cancers, making this the most frequently mutated chromatin regulator in human malignancies.

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12. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A wet-lab postdoctoral position is available immediately in the Northcott Lab (Department of Developmental Neurobiology) to join a highly collaborative team studying the developmental and molecular basis of the childhood brain tumor medulloblastoma. The Northcott Lab has established an internationally renowned track record in pediatric neuro-oncology, substantiated by numerous impactful publications in Nature, Cancer Cell, Lancet Oncology, and Journal of Clinical Oncology. Leveraging our exquisite access to patient material linked to large clinical trial cohorts, we are applying a combination of innovative, multi-omic approaches to discover new biological, mechanistic, and clinical insights responsible for medulloblastoma initiation, progression, and relapse.

Application Deadline: Open Until Filled

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13. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Abraham lab studies gene expression-regulation mechanisms in healthy and diseased mammalian cells. We are recruiting computational biologists to collaboratively develop computational tools and frameworks to analyze high-throughput sequencing (-omics) data. We build analytical software pipelines to find answers to biological questions about gene regulation in big datasets, usually from applied sequencing experiments like ChIP-Seq, RNA-Seq, and Hi-ChIP. Our interests center on enhancers and super-enhancers. Specifically, we seek to understand how these regulatory elements establish gene expression programs in healthy cells, and how enhancers are altered by mutation, abused by mistargeting, and targetable with drugs in diseased cells. 

Application Deadline: Open Until Filled

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14. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Advance hope, medical science, statistical science, and your career as a postdoctoral fellow in the Department of Biostatistics at St. Jude Children’s Research Hospital. A Ph.D. in statistics, biostatistics, computer science, or closely related field is required. Appointment is for two years. Applicants must have a strong computational background and demonstrate excellent written and verbal communication skills. 

Application Deadline: Open Until Filled

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15. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A fully funded postdoctoral position is available in the Clements group in the Department of Hematology at St. Jude Children’s Research Hospital to study how the adult hematopoietic system is established during vertebrate embryonic development. We are interested in understanding how early precursors of the sympathetic nervous system and vascular smooth muscle precursors interact with developing endothelial cells to establish the earliest hematopoietic stem cells. Our recent findings (Nature Cell Biology, 19:457-467, 2017) and unpublished data define the existence of this connection in in vertebrates and we are now working to better understand key details.

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16. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Crispino’s laboratory studies the biology of normal and malignant hematopoiesis with an emphasis on the factors that drive progression of benign disorders to acute leukemia. Research in the lab ranges from the basic science of transcription to translational research aimed at developing treatments for blood disorders. A current major focus of the lab is to understand the increased risk of leukemia in children with Down syndrome and the role of GATA1 mutations and DYRK1A in oncogenesis. 

Application Deadline: Open Until Filled

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17. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Kriwacki lab seeks to recruit a Postdoctoral Research Associate (PRA) to investigate the roles of biomolecular condensate formation in oncogenesis by fusion oncoproteins using molecular and cell biology methods, and fluorescence imaging approaches. We recently established that many fusion oncoproteins undergo phase separation to form condensates that drive aberrant gene expression or cell signaling (PMC10539325, PMC8983581, doi.org/10.1146/annurev-cancerbio-061421-122050). However, the biophysical mechanisms underlying condensate formation and how condensates alter cellular behavior are poorly understood. This PRA will work in a highly collaborative team environment with biochemists, biophysicists, data scientists and image analysis specialists to address fundamental questions surrounding fusion oncoproteins in pediatric cancers, including leukemias, brain tumors and sarcomas. 

Application Deadline: Open Until Filled

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18. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Immunology postdoctoral positions are available in the laboratory of Dr. Hongbo Chi in the Department of Immunology, St. Jude Children’s Research Hospital. The Chi lab investigates immunobiology and cancer immunology, by focusing on metabolic regulation of the immune system (immunometabolism) and its implications in cancer and other diseases. As metabolic pathways are inextricably connected to immunity and cancer, understanding these connections allows us to gain new insights into biological concepts and disease targets. We are particularly interested in understanding the metabolic programs (e.g., amino acid and lipid metabolism), signaling pathways (e.g., mTOR and nutrient-induced signaling), and systems-level regulatory networks (e.g., protein–protein or driver gene–target gene interactions) that regulate basic T cell and dendritic cell biology and antitumor immunity. 

Application Deadline: Open Until Filled

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19. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Several postdoctoral positions are available in the laboratory of Dr. Victor J. Torres in the new Department of Host-Microbe Interactions at St. Jude Children’s Research Hospital. The Torres lab is interested in dissecting the complex interactions between pathogenic bacteria and the mammalian host. Currently, the lab is focusing on antibiotic resistant (AMR) bacteria, which have been recognized by the World Health Organization as a serious threat to human health. We take advantage of multidisciplinary approaches and combine techniques from bacteriology, genetics, molecular biology, biochemistry, structural biology, cellular biology, and immunology with primary tissue culture models and a variety of murine models of infection, to address our favorite questions. 

Application Deadline: Open Until Filled

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20. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Li’s lab is dedicated to utilizing integrative approaches to decode dysregulated transcription networks in human cancers, and it is particularly interested in MLL-rearranged leukemias. Using cutting-edge technologies and multidisciplinary approaches, including genetic and epigenomic CRISPR editing, comprehensive screens, and an optimized auxin-induced protein degradation system (AID2.0), the lab investigates how transcription factors, epigenetic modifiers, chromatin looping factors, and noncoding segments regulate gene transcription, chromatin architecture, and chromatin accessibility maintenance in human cancer cells. 

Application Deadline: Open Until Filled

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21. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A post-doctoral position is available in the laboratory of David Rogers in the field of molecular mycology in the area of antifungal drug resistance. The overarching goal of the Rogers lab is to utilize genome-wide and molecular biological approaches to understand the molecular and genetic basis of antifungal drug resistance in pathogenic opportunistic fungi. The long-term goal of this project is to advance the treatment of invasive candidiasis by identifying the molecular mechanisms underpinning antifungal resistance in the emerging fungal pathogen Candida auris, and to ultimately use this understanding to design therapeutic strategies to overcome them. Our immediate objective is to fully understand the genetic and molecular basis of antifungal resistance in clinical isolates of C. auris.

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22. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

As a part of the Center of Excellence for Data-Driven Discovery in the Department of Structural Biology at St. Jude Children’s Research Hospital, the Babu Group seeks a highly driven, full-time Postdoctoral Research Associate to develop computational pipelines and machine learning approaches to quantify obesity risk and predict its effects by leveraging large-scale omics data.

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23. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Cancer Stem Cell Dynamics laboratory of Dirk Loeffler is seeking exceptionally motivated and ambitious candidates for a Postdoctoral Position, starting Jan. 1st, 2024, or the earliest date thereafter. If you are curious, creative, and goal-oriented with a keen interest in science, technology, and data this is the right position for you!
We study the genetic and epigenetic changes in blood stem and progenitor cells during hematopoietic diseases and aging. The ideal candidate is curious, self-motivated, independent, hard-working, and has excellent communication and interpersonal skills. Experiences in cell and molecular biology or related fields and a strong desire to learn new techniques are prerequisites. A background in hematology is preferred but not required and candidates from a wide variety of fields with a genuine interest in stem cells and the origins of cancer are encouraged to apply.

Application Deadline: Open Until Filled

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24. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Immunology postdoctoral positions are available in the laboratory of Dr. Bo Hu in the Department of Immunology, St. Jude Children’s Research Hospital. The Hu lab investigates immunobiology, immunometabolism, and neuroimmunology, by focusing on the interaction of the immune system and the nervous system and its implications for health and diseases. As the immune system and nervous system are tightly connected to regulate host physiology and pathology, understanding these connections allows us to gain new insights into biological concepts and disease targets.

Application Deadline: Open Until Filled

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