Are you holding PhD degree and looking for Postdoctoral Fellowships? St. Jude Children’s Research Hospital, Tennessee invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.
1. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The project aims to understand how KDMs coopts oncogenic transcription factors to drive tumorigenesis and metastasis, and use novel KDM inhibitors to target metastasis and disease relapse. To this end, we apply interdisciplinary strategies by integrating genetic approaches (transgenic mouse models and conditional knockout) with cutting-edge systems (Cut&Tag, HiChIP, ATAC-seq, scRNA-seq, spatial transcriptomics), and functional genomics tools (Genome-wide and focused CRISPR libraries, CRISPR knockin, CRIPSRi and CRISPRa) as well as proteomics and metabolomics.
Application Deadline: Open Until Filled
2. Postdoctoral Position
Summary of Postdoctoral Fellowship:
You will be part of an interdisciplinary team that uses modern structural biology (variable temperature crystallography) to characterize disease-relevant protein states, computational methods (MD, docking, custom software) to analyze and exploit them, and experiments (biophysical, biochemical, cell-based assays) to test the impact of small molecules on biology and disease.
Application Deadline: Open Until Filled
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3. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A postdoctoral position is available in the Chang lab in the Department of Cell & Molecular Biology at St. Jude Children’s Research Hospital. We are looking for highly talented, self-motivated individuals passionate about how organelles communicate. In particular, the candidate will interrogate the fundamental questions of ER-to-Golgi trafficking via cutting-edge light and electron microscopy, genome-editing, biochemistry and in vitro reconstitution approaches. Prerequisites are creativity, dedication, and the ability to work collaboratively in a small group.
Application Deadline: Open Until Filled
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4. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The laboratory of Dr. Peijun Ma in the Department of Pharmacy and Pharmaceutical Sciences in St. Jude Children’s Research Hospital, Memphis, TN is a new research group that uses single-cell genomics and transcriptomics to study antibiotic resistance and persistence in bacterial pathogens. Past work has focused on developing bacterial single-cell RNA sequencing technology (Ma et al., Cell, 2023;) and understanding the evolution of antibiotic resistance in gram-negative bacterial pathogens (Ma et al., eLife, 2021;).
Application Deadline: Open Until Filled
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5. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Chen Lab is recognized for developing innovative machine learning and statical learning approaches and has led intratumoral heterogeneity and epigenetic deregaultions in pediatric cancers, spearheaded publications in Nature, Genome Biology, Nucleic Acid Research, Neuron, Cancer Cells, Developmental Cells, Science immunology and Nature Communications in the last five years and is funded by the NCI. St. Jude offers a highly interactive and supportive environment for researchers’ career development, including state-of-the-art high-performance computing facilities, robust analytical pipelines, the latest wet-lab technology, access to outstanding core facilities and scientific expertise in genomics, cancer biology, statistics, and computer science.
Application Deadline: Open Until Filled
6. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Several postdoctoral positions are available in the laboratory of Dr. Victor J. Torres in the new Department of Host-Microbe Interactions at St. Jude Children’s Research Hospital. The Torres lab is interested in dissecting the complex interactions between pathogenic bacteria and the mammalian host. Currently, the lab is focusing on antibiotic resistant (AMR) bacteria, which have been recognized by the World Health Organization as a serious threat to human health. We take advantage of multidisciplinary approaches and combine techniques from bacteriology, genetics, molecular biology, biochemistry, structural biology, cellular biology, and immunology with primary tissue culture models and a variety of murine models of infection, to address our favorite questions.
Application Deadline: Open Until Filled
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7. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Yu Lab within the Department of Computational Biology is currently seeking exceptional candidates for a Postdoctoral Research Associate position with a focus on single-cell & spatial omics and systems immunology. The Yu Lab is dedicated to developing advanced systems biology algorithms, such as NetBID (Du, Nature 2018), NetBID2 (Dong, Nat Common, 2023), and scMINER (Ding, in revision). These algorithms integrate multi-omics data at both bulk and single-cell levels to dissect intracellular and intercellular network dynamics in healthy and diseased states, identify underlying hidden drivers, and ultimately translate these discoveries into potential clinical applications.
Application Deadline: Open Until Filled
8. Postdoctoral Position
Summary of Postdoctoral Fellowship:
We are seeking a highly motivated Postdoc Research Associate to join Dr. Ji Sun’s lab at St. Jude Children’s Research Hospital. Successful candidates will lead research projects focusing on disease-causing protein complexes, using an integrative approach combining structural, biochemical, and cell biology methods (Myasnikov A et al., Cell 2021; Zhu H et al., Biorxiv 2022, Jiang M et al., Cell Research, 2023). The lab has full access to the state-of-the-art cryo-EM facility in St. Jude, which houses a 300kV Titan Krios and a 200 kV Talos Arctica electron microscope equipped with K3 detectors.
Application Deadline: Open Until Filled
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9. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Chen Lab studies: i) Chemical modulation of transcription; ii) Signal crosstalk among transcription factors; and iii) Selective inhibition of highly homologous enzymes. We take a hypothesis-driven and technology-enabled multidisciplinary approach to develop chemical probes and investigate biological mechanisms. Particularly we use the promiscuous xenobiotic nuclear receptors (PXR and CAR) as models to investigate the transcription networks that regulate therapeutic responses. PXR and CAR regulate the detoxification system (e.g., by transcriptionally controlling CYP3A4 and CYP3A5—drug-metabolizing enzymes that metabolize more than 50% of clinical drugs), the dysregulation of which contributes to drug toxicity and drug resistance.
Application Deadline: Open Until Filled
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10. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A wet-lab postdoctoral position is available immediately in the Northcott Lab (Department of Developmental Neurobiology) to join a highly collaborative team studying the developmental and molecular basis of the childhood brain tumor medulloblastoma. The Northcott Lab has established an internationally renowned track record in pediatric neuro-oncology, substantiated by numerous impactful publications in Nature, Cancer Cell, Lancet Oncology, and Journal of Clinical Oncology. Leveraging our exquisite access to patient material linked to large clinical trial cohorts, we are applying a combination of innovative, multi-omic approaches to discover new biological, mechanistic, and clinical insights responsible for medulloblastoma initiation, progression, and relapse.
Application Deadline: Open Until Filled
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11. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Vevea Lab seeks to understand the cell biology of the axon. More specifically, we want to understand how the synaptic vesicle cycle is established and maintained throughout the age of the organism. This focus leads us to ask questions about cellular processes related to organelle polarity and trafficking in the axon, organelle and protein quality control in the neuron, and to examine the fundamental function of proteins that influence the synaptic vesicle cycle but still have unclear or disputed functions.
Application Deadline: Open Until Filled
12. Postdoctoral Position
Summary of Postdoctoral Fellowship:
An exciting career opportunity is available for a postdoctoral researcher in the laboratory of Dr. Andrew Davidoff to explore novel gene therapy and small molecule techniques in the treatment of solid tumors. The Davidoff lab seeks an inventive researcher to develop novel gene therapy vectors and test them in our translational models of neuroblastoma and liver cancers. The ideal candidate will have experience with models of solid tumors and/or AAV-based gene therapy vectors, to seek innovative cures for rare pediatric cancers.
Application Deadline: Open Until Filled
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13. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Tsai Laboratory is seeking dynamic and creative candidates for a fully supported postdoctoral fellowship on genome editing technologies for therapeutic treatment of genetic disorders. CRISPR genome editors, adapted from bacterial adaptive immune systems, are transforming both basic biological research and genomic medicine. At St. Jude, we are working toward advancing these technologies towards patient treatments for sickle cell disease and bone marrow failure disorders.
Application Deadline: Open Until Filled
14. Postdoctoral Position
Summary of Postdoctoral Fellowship:
HSCs represent the most therapeutically exploited adult stem cell compartment, used routinely to treat leukemia and hematologic disease via HSC transplantation. Indeed, HSC transplantation represents the only cure for Sickle Cell Disease, including autologous HSC transplantation combined with gene therapy. Here, our major goals are to better understand how elevated hematopoietic demand and chronic inflammation associated with Sickle Cell Disease perturbs the phenotype and function of HSCs. We employ both genetic mammalian model systems and primary patient samples to pursue these aims.
Application Deadline: Open Until Filled
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15. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The fundamental goal of our research is to understand how neural circuits control movement. We approach this from multiple perspectives, using cutting-edge technologies to analyze the molecular diversity of spinal interneurons, explore how descending systems in the brain convey information to the spinal motor system, and define the functional roles of spinal interneurons in generating behavior.
Application Deadline: Open Until Filled
16. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Postdoctoral positions are immediately available in the laboratory of Dr. Mark Leggas in the Department of Pharmacy and Pharmaceutical Sciences to study the pharmacology and effects of treatment in infants with neonatal abstinence syndrome. We are looking for highly motivated candidates with experience in one or more of the following areas: a) pharmacogenetics or epigenetics, b) microbiome, and c) bioinformatics of lipidomic and/or metabolomic workflows.
Application Deadline: Open Until Filled
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17. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Advance hope, medical science, statistical science, and your career as a postdoctoral fellow in the Department of Biostatistics at St. Jude Children’s Research Hospital. As a fellow you will join our faculty in the Department of Biostatistics in providing statistical support and developing innovative statistical methods for research projects at the cutting edge of biomedical research. A position is available in statistical research to develop and improve individualized treatment rules using machine learning methods on electronic health records data and clinical trial studies.
Application Deadline: Open Until Filled
18. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Gottschalk Laboratory is seeking a highly motivated and creative candidate for a fully supported postdoctoral fellowship to develop immune-based therapies. Specifically, the research is aimed to develop T-cell-based therapies for pediatric solid tumors. Studies are focused on using genetic engineering approaches to not only render immune cells cancer specific, but also improve their effector function. Genetically modified immune cells will be studied in preclinical models with special emphasis on how adoptively transferred cells interact with tumor cells, the tumor microenvironment, and resident immune cells. Ultimate goal of these studies is to translate these approaches into early Phase clinical testing.
Application Deadline: Open Until Filled
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19. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Abraham lab studies gene expression-regulation mechanisms in healthy and diseased mammalian cells. We are recruiting computational biologists to collaboratively develop computational tools and frameworks to analyze high-throughput sequencing (-omics) data. We build analytical software pipelines to find answers to biological questions about gene regulation in big datasets, usually from applied sequencing experiments like ChIP-Seq, RNA-Seq, and Hi-ChIP. Our interests center on enhancers and super-enhancers. Specifically, we seek to understand how these regulatory elements establish gene expression programs in healthy cells, and how enhancers are altered by mutation, abused by mistargeting, and targetable with drugs in diseased cells.
Application Deadline: Open Until Filled
