Are you holding PhD degree and looking for Postdoctoral Fellowships? University of Pennsylvania, Pennsylvania, USA invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.
1. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Seeking a talented and highly motivated postdoctoral fellow to collaborate on research aimed at reducing the burden of breast cancer, particularly for racial/ethnic minorities, through precision prevention approaches. The postdoctoral fellow will work under the direct supervision of Dr. Anne Marie McCarthy, a cancer epidemiologist at the University of Pennsylvania Perelman School of Medicine in the Department of Epidemiology, Biostatistics, and Informatics. Projects will cover topic areas including breast cancer risk prediction, integration of genetics into breast cancer prevention, evaluation of novel imaging biomarkers of breast cancer risk, personalized screening, and racial disparities in breast cancer. Flexible start date.
Application Deadline: Open Until Filled
2. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Conn Lab is looking for 1-2 postdocs focused on post-transcriptional gene regulation and the roles of RNA-binding proteins, RNA modifications, and signaling that are rewired during cancer progression. One project is focused on identifying regulators of selective translation and spatial RNA interactions in the cell during drug resistance in prostate cancer (more mechanism to move into translational research later). The other project is looking at adaptive stress responses in pancreatic tumors and will require mouse modeling, tissue analysis, and treatments in vivo. The lab has received two awards, over 3 years of DoD funding for project one and has independent funds for project two.
Application Deadline: Open Until Filled
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3. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Postdoctoral Researcher will be co-mentored by three PIs: Edward (Ted) Brodkin, MD (Co-Director of ASPE); Maja Bucan, PhD (Co-Director of ASPE); and Laura Almasy, PhD (co-Investigator, ASPE). The Brodkin lab spearheads ASPE’s recruitment, enrollment, and phenotyping efforts, and Dr. Brodkin has expertise in the human phenotypes associated with autism spectrum disorder (ASD), quantitative phenotypes for genomic studies, translational biology, and treatment development. The Bucan lab focuses on delineating the genetic basis of autism-relevant traits and genotype-phenotype relationships in the ASPE cohort, and Dr. Bucan brings to ASPE an expertise in genomics and complex trait analysis, family-based studies of human disease, and bioinformatics.
Application Deadline: Open Until Filled
4. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The focus of our lab’s research is at the intersection of immunology, metabolism, and brain tumor biology. The primary goal of our translational research is to understand mechanisms of immune evasion by primary malignant brain tumors and skull base tumors to generate novel immune-based therapies. We utilize a combination of high-dimensional single cell immune and genomic profiling, metabolomics, and advanced tumor organoid and mouse models, to 1) understand the role of myeloid derived suppressor cells in promoting tumor growth and T cell dysfunction, 2) elucidate the mechanisms of tumor-specific T cell exhaustion and clonal lineage of dysfunction T cells, and 3) understand how metabolic networks control immune cell function within the tumor microenvironment.
Application Deadline: Open Until Filled
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5. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A Postdoctoral Researcher position is available for a highly motivated applicant in the laboratory of Dr. Fiona Simpkins at the University of Pennsylvania. Our focuses are to understand resistance mechanisms to targeted therapies such as DNA Damage Repair inhibitors (DDRi), to sequence DDRi with Immuno-Oncology (IO) drugs, and to identify biomarkers or response to these agents. We have developed a preclinical drug development program in the Ovarian Cancer Research Center with the goal of moving novel laboratory therapeutic discoveries into the clinic. We have developed >150 patient derived xenografts (PDX) models, patient-derived organoids, and primary tumor cultures from ovarian and endometrial cancers. These PDX models mimic the original tumors, thereby accelerating the translation of preclinical study results into clinical trials for patients. Also, we are “humanizing” our models by autologous tumor infiltrating lymphocyte (TIL) and macrophage (TAM) transfer, creating an autologous in vivo model system.
Application Deadline: Open Until Filled
6. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A postdoctoral position is immediately available in the laboratory of Dr. Alessandra Chesi at the University of Pennsylvania with a focus on discovering and functionally characterizing novel genes for Alzheimer’s, Parkinson’s and other neurodegenerative diseases in human brain relevant cell types. Dr. Chesi has a long-standing interest in genomics and neurodegenerative diseases; she has developed Capture C based approaches to map GWAS signals to their effector genes (see some examples in linked publications) and is applying them to brain-related disorders.
Application Deadline: Open Until Filled
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7. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Wilson laboratory in the Division of Diagnostic Innovation in the Department of Pathology and Laboratory Medicine at Penn is hiring a postdoctoral fellow to work on an established project focused on single cell and spatial analysis of human diabetic kidney disease. This position involves both dry lab and wet lab responsibilities and will consider applicants with experience in either area. The fellow will conduct single cell analysis of human donor specimens from patients with diabetic kidney disease under the supervision of Dr. Wilson. We have already sequenced a large number of single cell libraries in collaboration with Novo Nordisk and preprocessed our dataset for downstream analysis. We are looking for a motivated individual who can work together with our research team to complete any necessary validation studies and move this project to publication. Prior coding experience is not required and the position can be tailored to the applicant skillset. Applicants with bioinformatics experience may be interested in single cell or spatial analysis techniques whereas applicants with molecular biology experience could focus on assay development and cell culture models of diabetic kidney injury.
Application Deadline: Open Until Filled
8. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Postdoctoral positions are available in the laboratory of Marcelo Kazanietz at the Perelman School of Medicine, University of Pennsylvania, Philadelphia to study basic and translational aspects of cancer signaling, with particular focus in lung and prostate cancer. Requirements: We are looking for highly motivated postdoctoral fellows with demonstrated ability to lead a research project and work independently. Interested candidates should have a PhD and/or MD degree, preferentially no more than 2 years postdoctoral experience, and strong background in cellular and molecular biology. Expertise in cellular and animal models of cancer as well as an excellent publication record in cancer signaling is preferred.
Application Deadline: Open Until Filled
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9. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The position will report to Dr. Daniel Hashimoto with additional collaboration and mentorship from Drs. Kostas Daniilidis and Eric Eaton of Penn Engineering. The compensation package includes a competitive salary, health benefits, career mentoring, and conference travel support. The position offers opportunities to work with medical device industry collaborators and to be involved in leadership of national and international collaborative research projects through the Global Surgical AI Collaborative. The post doc will have access to resources through both the School of Medicine and the GRASP Lab at Penn Engineering.
Application Deadline: Open Until Filled
10. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A one year POSTDOCTORAL POSITION (with the option to extend an additional 1-3 years) is available to continue and expand studies into the mechanisms by which select virus-host interactions regulate entry and/or egress of emerging RNA viruses including Ebola, Marburg, and Lassa fever (as described in Liang et al., 2021 J. Virol.; 2022 J. Virol.; 2023 PNAS; and Han et al., 2020 PLOS Pathog.; 2020 J. Biol. Chem.; 2021 Antimicrob. Agents Chemotherapy.
Application Deadline: Open Until Filled
11. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Laboratory for Imaging Physics, Analysis, and Clinical translation (IMPACT) is seeking highly motivated individuals to join a number of NIH-funded projects. The IMPACT Lab is directed by Dr. Grace J. Gang and is located in the Department Radiology at the University of Pennsylvania. Our lab is dedicated to developing novel imaging technologies guided by a rigorous understanding of imaging science. Projects in the lab contain a mix of theoretical image chain modeling, benchtop experimentation, and technology integration on clinical imaging system.
Multiple positions open for full-time research scientists or postdoctoral researchers. We are seeking candidates for a number of projects including development and evaluation of deep learning image formation algorithms, system design and optimization for spectral imaging, and developing analytical and deep learning strategies for radiomics standardization.
Application Deadline: Open Until Filled
12. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A postdoctoral position in cellular therapies for solid cancer is available immediately. The postdoc will investigate novel cellular therapies using gamma delta CAR-T cells for solid tumors using state-of-the-art technologies at the University of Pennsylvania. Training will be provided.
Application Deadline: Open Until Filled
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13. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Applications are invited for a postdoctoral position in the laboratory of Dr. Daniel J. Rader at the Perelman School of Medicine (PSOM) of the University of Pennsylvania. This position offers an opportunity to work in a highly collaborative, multidisciplinary research environment focusing on the human genetics of cardiometabolic traits and diseases, the elucidation of novel molecular and physiological mechanisms underlying these phenotypes, and new approaches to therapeutic interventions based on this knowledge. Approaches to this work may include computational genomics, cell-based and/or mouse model systems, protein structure-function relationships, characterizing the functional effects of naturally-occurring coding variants, and human-based mechanistic studies.
Application Deadline: Open Until Filled
14. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A postdoctoral Researcher position is available in the laboratory of Dr. Jianxin You at the University of Pennsylvania Perelman School of Medicine. The laboratory investigates how the molecular interplay between oncogenic viruses and their host cells leads to cancer (Cell 117:349-360, Cell Host Microbe 19:775-87). We are also developing nanotechnology-based immunotherapy for eliciting antiviral and antitumor immunity (Proc Natl Acad Sci U S A. 2020;117:13730-13739)
Application Deadline: Open Until Filled
15. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Two postdoctoral researcher positions are available in the laboratory of Dr. Xiaolu Yang at the Perelman School of Medicine at the University of Pennsylvania. The Yang lab studies cancer and neurodegenerative diseases. Our current projects focus on two broad areas:
(1) The tumor suppressor p53, metabolism, and autophagy. We are interested in the regulation and functions of the preeminent tumor suppressor p53. Our results have revealed a role for p53 in modulating metabolic pathways that are critical for biosynthesis and redox balance. We are investigating the function of p53 as both a sentinel and a regulator for metabolic activities. We are also identifying and characterizing metabolic alterations that drive tumor initiation and progression. A recent extension of this research area is to define the role of metabolism and autophagy in stem cells, including embryonic stem cells and cancer stem cells.
(2) Protein quality control, aging, and neurodegeneration. Our lab recently identified two protein quality control (PQC) systems, which consist of tripartite motif (TRIM) proteins and poly-Asp/Glu (polyD/E) proteins, respectively. Unlike canonical PQC systems, these new systems are independent of ATP and are unique for animals (the TRIM system) or eukaryotes (the polyD/E system). Both systems are multifunctional and highly effective. We are investigating their mechanisms of action; their roles in aging and neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis; and their utility in treating these diseases.
Application Deadline: Open Until Filled
16. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Feldser Lab is looking for a postdoc to study the cell and molecular requirements for PKC signaling during Kras-mediated tumor initiation. The lab has received NIH funding for a 5 year project to begin immediately.
Application Deadline: Open Until Filled
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17. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Bowman Laboratory is seeking to fill a postdoctoral fellow position to study clonal evolution in leukemia. Applicants with a recent PhD or MD/PhD with experience in animal modeling of disease or computational modeling of system dynamics are invited to apply.
Application Deadline: Open Until Filled
