Are you holding Master’s degree and looking for fully funded PhD positions? Karolinska Institute, Sweden invites online application for multiple funded PhD Programs / fully funded PhD positions in various research areas.
Candidates interested in fully funded PhD positions can check the details and may apply as soon as possible. Interested and eligible applicants may submit their online application for PhD programs via the University’s Online Application Portal.
1. Fully Funded PhD Position in Single cell analysis of the developing and aging inner ear
Summary of PhD Program:
The Lallemend lab is devoted to studying the genetic and molecular aspects of the peripheral sensory system, including development, identity, function, and plasticity (Nat Commun 2018, Cell Rep 2019, Nat Commun 2019, Nat Commun 2021, Nat Commun 2022). The PhD student will be responsible for investigating the transcriptional and epigenetic landscape of the inner ear at the single-cell level, examining the impact of metabolism and genetic background, and quantifying the genetic pathways involved in the emergence and senescence of a whole sensory organ during early development and aging. This research is basic and translational as it will have implications for the identification of new molecular targets to counter aging or rejuvenate the organs’ function.
Application Deadline: 22.Aug.2023
2. Fully Funded PhD Position in Virus-Host interactions
Summary of PhD Program:
Increasing evidence indicates the role of imbalanced immunometabolism in the virus-induced pathology. These cellular functions are regulated by post-translational modifications by ubiquitin and ubiquitin-like polypeptides (UbLs), such as ISG15. Interfering with the UbL-dependent processes through deconjugation is a powerful strategy used by the virus to dysregulate cell intrinsic defenses and promote infection. Viral proteases encoded by RNA viruses like the Coronavirus papain-like protease (PLpro) and Nairovirus OTU-like protease (Crimean Congo hemorrhagic fever virus, CCHFV-L1 protein) has deubiquitinase (DUB) and deISGylase (DISG) activity, which can cause antiviral and metabolic reprogramming.
Application Deadline: 15.Jul.2023
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3. Fully Funded PhD Position in Neuroplasticity and regeneration
Summary of PhD Program:
An intriguing feature of the nervous system is plasticity, the remarkable lifelong capacity to change and adapt in light of intrinsic and extrinsic stimuli. The doctoral project aims at providing a comprehensive understanding of the neuronal plasticity (mechanisms and structural changes) contribution to neuroprotection and regeneration of spinal networks after injury. Thus, the outlined research can deliver new, essential knowledge regarding the organization and dynamic adaptations of the adult spinal networks. The results are expected to have a substantial impact because the experiments are designed to lay the groundwork for the development of new, targeted treatments for SCI and other spinal neurodegenerative diseases.
Application Deadline: 15.Jul.2023
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4. Fully Funded PhD Position in Molecular Aging
Summary of PhD Program:
The PhD student is expected to participate in the experimental design, experimentation, analysis, and presentation/publication of research results. The research work includes standard molecular biological techniques, immunostainings, base scope, histology, cell culture, next generation applications for genome-wide analysis (single-cell and bulk sequencing), and digital droplet PCR. We use tissue samples from patients and model systems. The student is expected to be part of the group and to develop in accordance with the common group goals and research interests.
Application Deadline: Open until filled
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5. Fully Funded PhD Position in developing 3D imaging techniques for studies of intact biological tissues
Summary of PhD Program:
Professor Per Uhlén’s research laboratory, located within the Unit of Molecular Neurobiology at the Department of Medical Biochemistry and Biophysics (MBB) in Karolinska Institutet, Solna, is renowned for its pioneering work in the imaging field. Our team excels in developing advanced 3D imaging technologies, and we have published groundbreaking research in cancer and neuroscience applications (Tanaka N, et al., Nature Biomedical Engineering, 2017 and 2020, and Kanatani S, et al., bioRxiv, 2022). Our primary objectives are to enhance the understanding of tissue architecture of the central nervous system and tissue heterogeneity in cancer, as well as to develop cutting-edge imaging tools.
Application Deadline: 30.Jun.2023
6. Fully Funded PhD Position in Translational Breast cancer research
Summary of PhD Program:
We are seeking a highly motivated PhD student to join our team who is dedicated to improving the understanding of breast cancer and factors related to the development of metastatic disease and fatal breast cancer. Who has a high risk of dying from the disease and why? Breast cancer is a very heterogeneous disease both with regards to tumor biology, metastatic capacity and time to fatal disease. For instance, younger women are known to have a higher risk to die from their disease compared to middle-aged women, but the underlying reasons are not understood.
Application Deadline: 27.Jun.2023
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7. Fully Funded PhD Position in RNA-mediated DNA repair in cancer
Summary of PhD Program:
The position is placed in the laboratory of Marianne Farnebo, that studies the function of non-coding RNA and RNA-binding proteins in DNA repair and nuclear organization, and how defects in these processes contribute to cancer. A number of techniques required to study RNA and DNA repair are already up and running in Farnebo laboratory, including RNA immunoprecipitation, RNA FISH, generation of site-specific DNA damage and various biochemical approaches.
Application Deadline: 23.Jun.2023
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8. Fully Funded PhD Position in Covid-19 and mental health
Summary of PhD Program:
The COVID-19 pandemic, and its resulting societal, behavioral and economic changes, have had widespread impacts on population health, including mental health. This doctoral project will investigate the mental health of individuals with COVID-19, their families, and the general population, both before and during the COVID-19 pandemic. We will use unique research materials, including register data, in Sweden, and will collaborate with international research groups from other Nordic countries and beyond. As a doctoral student, you are expected to lead the individual studies in the PhD thesis, including project coordination, study design, data collection, data analysis, manuscript writing, and result dissemination.
Application Deadline: 22.Jun.2023
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9. Fully Funded PhD Position in genomic analyses of neurons
Summary of PhD Program:
This PhD project is focused on investigating how alternative splicing is functionally affecting our brain. The project is to a large degree dependent on computational analyses of deep Smart-seq data from the brain to elucidate the extent and general rules for how splicing affects the brains cell types and functional connections. This has relevance for human disease. The candidate will handle large data and learn all aspects from sequencing technologies, bioinformatics, computational biology, experimental neuroscience, and exploring high-dimensional data for biological patterns.
Application Deadline: 21.Jun.2023
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10. Fully Funded PhD Position in Translational Cancer Metabolism
Summary of PhD Program:
The goal of this doctoral project is to identify new factors that are critical to drive non-small cell lung cancer (NSCLC) development and progression. The specific aim is to define differential gene expression patterns and to identify which metabolic states exists across NSCLC pathogenesis. Thus, the work will involve biopsy collection in the hospital and sample preparation for metabolomics, genomics and transcriptomics approaches, analysis of data, bioinformatics on the obtained data. Once this is established, validation and targeting of identified metabolic signatures/nodes will be experimentally tested in cell lines and mouse models.
Application Deadline: 21.Jun.2023
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11. Fully Funded PhD Position in computational pathology
Summary of PhD Program:
This PhD position will include both methods development and applied research in the area of computational pathology in cancer, where applications of computer vision, deep learning and machine learning methodologies are central. The research will include multiple data modalities, such as histopathology images, molecular profiling data, and clinical data. Under supervision, the PhD student will be responsible for literature review, model implementation, data analysis, result interpretation, scientific article writing and data presentation.
Application Deadline: 16.Jun.2023
12. Fully Funded PhD Position in Untangling mechanisms underlying mechano-translation
Summary of PhD Program:
The doctoral student will use newly developed large-scale approaches and algorithms to study how a repertoire of mechanisms determine patterns of mRNA translation in cancer depending on tissue composition. Many of the data sets will be generated in close collaboration with Staffan Strömblad (KI), who is an expert in mechanotransduction. The importance of the identified mechanisms for cancer phenotypes can then be evaluated and patient subgroups showing alterations in these mechanisms can be identified. These studies may thereby enable precision medicine approaches for cancer treatment.
Application Deadline: 15.Jun.2023
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13. Fully Funded PhD Position in Health Sciences
Summary of PhD Program:
The current research project aims to increase the knowledge and awareness of ethical stress among healthcare staff in the emergency department and to develop a model for routinely managing ethical stress. The project as a whole has the potential to contribute to an improved working environment in the emergency departments included in the study. More specifically, the doctoral project is divided into four sub-studies where the first one focuses on investigating the occurrence and experience of ethical stress in different care professions at two emergency departments in Region Stockholm.
Application Deadline: 2023-06-14
14. Fully Funded PhD Position in Biostatistics
Summary of PhD Program:
The successful applicant will work on the development and application of statistical models for studying breast cancer tumour progression, patient survival and mammography screening outcomes. The project will include analyses of data from large, detailed studies of breast cancer and mammography screening (with large-scale genetics and image data). The student will interact with other academic statisticians and with specialists in other fields, e.g. cancer epidemiology and screening.
