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10 Fully Funded PhD Programs at University of Plymouth, England

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Are you holding Master’s degree and looking for fully funded PhD positions? University of Plymouth, England invites online application for multiple funded PhD Programs / fully funded PhD positions in various research areas.

Candidates interested in fully funded PhD positions can check the details and may apply as soon as possible. Interested and eligible applicants may submit their online application for PhD programs via the University’s Online Application Portal. 

1. Fully Funded PhD Position in Predicting developmental responses to environmental challenge

Summary of PhD Program:

Organismal development is an incredibly dynamic and sensitive process and for many species it is occurring in an increasingly volatile environment. Yet within a species, there exists significant inter-individual variability in the development of both an embryo’s form and function and this can have significant implications for both individual organisms and evolutionary processes. This PhD studentship will use high-throughput bioimaging and deep learning to investigate the extent to which biological variation in unstable environments can be used to predict later biological processes, sensitivities and outcomes. The overarching goal is to test the predictive capacity of variation in developing organisms.

Application Deadline: 3 June 2024

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2. Fully Funded PhD Position in Determining the dietary accumulation and toxicity of nanoplastics and co-contaminants (zinc oxide nanomaterials) in fish

Summary of PhD Program:

Plastic pollution represents a global environmental challenge. The larger plastic particles can degrade to produce/release nanoplastics (NPs) that can enter the tissues of aquatic organisms. For example, up to 700,000 nanoplastics can pass across the gut of fish in four hours and once in the body, these NPs can enter the internal organs. However, linking accumulation with the effects on the gut epithelium, and the cellular storage and remobilization (i.e., excretion) following chronic exposure, remains unexplored. 

Application Deadline: 24 May 2024

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3. Fully Funded PhD Position in Joint Education of the Innovative Student in Marine Renewable Energy

Summary of PhD Program:

We have signed an agreement with the Ocean University of China (OUC) which gives PhD students the opportunity to engage in research in marine and offshore renewable energy at OUC and vice versa. Students will have co-supervisors from each institution. The scheme is funded by China Scholarship Council funding, CSC, supporting PhD students to study abroad.

Application Deadline: Open until filled

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4. Fully Funded PhD Position in The mechanisms of pressure and gas mediated neuroplasticity in the human brain

Summary of PhD Program:

While hyperbaric oxygen therapy (HBOT) is widely applied to treat a range of neurological and psychiatric disorders in countries around the world, the evidence threshold for implementation in the UK (NHS) has not yet been established. Moreover, the lack of a mechanistic understanding of the effects of altered oxygen concentration and pressure on the human brain limits the implementation and optimization of treatment protocols.

Building upon the findings of our recent studies, this PhD will systematically test the hypothesis that broad improvements in cognitive and behavioural performance are the result of an increase in neuroplasticity driven by oxygen and pressure related neural change. The project will exploit the multimodal neuroimaging, brain stimulation, cognitive and behavioural assessment capability at BRIC to investigate the structural, functional, and pharmacological effects of hyperbaric, hypobaric, and altered gas environments available at DDRC. 

Application Deadline: 7 June 2024

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5. Fully Funded PhD Position in Delivering Functional Imagery Training via generative AI to improve access to effective psychological interventions for health

Summary of PhD Program:

This project will develop datasets and software to deliver Functional Imagery Training (FIT) via mobile devices and, ultimately, via embodied agents (robots). As a person-centred intervention, FIT presents an interesting challenge: the practitioner or AI must tailor responses to the content of what the ‘client’ says, and guide mental imagery exercises based on that personal content. By building an interdisciplinary team of psychologists and machine learning experts this project will deliver real-world impact with broad implications for mental healthcare.

Application Deadline: 29 May 2024

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6. Fully Funded PhD Position in Investigating the role of eye movement in scleral growth

Summary of PhD Program:

Are you fascinated by how our eyes work and eager to make a difference in the fight against vision problems? Join our research team and help develop a revolutionary model to understand the impact of eye movements on eye health, with a focus on myopia (nearsightedness).

The project:

  • Design and validate an innovative in-vitro model to investigate the impact of mechanical forces on eye health and structure.
  • Explore the fundamental relationship between eye movements, the growth of the sclera (the white part of the eye), and myopia development.
  • Collaborate on investigating existing and novel drugs with the potential to shape improved myopia treatments.
  • Work with porcine and human eye tissues to advance our understanding of cellular responses.

Application Deadline: 31 May 2024

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7. Fully Funded PhD Position in Endotoxin tolerization of macrophage-mediated inflammatory processes in an oral 3D-mucosal tissue model

Summary of PhD Program:

Mucosal macrophages can be activated and drive tissue-destructive inflammatory processes. Endotoxin tolerization is a process of repeated microbial stimulation that suppresses inflammation and regulates this tissue destruction. These processes are understood in mono-culture, but poorly understood in poly-culture, whereby cell-to-cell interactions present in oral mucosal tissue can exert both positive and negative effects on these tolerance-fate decisions. We have developed an organotypic 3D immune-competent oral mucosal model to investigate the role of cellular interactions in modulating endotoxin tolerance. Such investigations will progress our understanding towards clinical translatability of controlling macrophage TLR-driven inflammatory responses in chronic periodontitis. 

Application Deadline: 31 May 2024

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8. Fully Funded PhD Position in Exploring immunosuppression in glioblastoma via high-throughput genomic screens

Summary of PhD Program:

One major reason for treatment failure in glioblastoma is that tumour cells secrete several immunosuppressive factors that alter the functions of immune cells in the tumour microenvironment. Hence, a successful treatment should inhibit the secretion of these immunosuppressive factors and subsequently block the bi-directional communication between the tumour cells and their microenvironment. Identification of genes regulating cell secretion requires a combination of a genetic screening tool (e.g., CRISPR) and a high throughput secretion assay capable of sorting large number of tumour cells based on their secretion patterns. This is not feasible with existing high-throughput cell secretion approaches that typically measure target production rather than secretion.

Application Deadline: 31 May 2024

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9. Fully Funded PhD Position in Identification of lung cancer patients at higher risk for brain metastasis using microfluidics

Summary of PhD Program:

Up to 55% of the patients with advanced non-small cell lung cancer (NSCLC) develop brain metastases with a median survival of 2–3 and 4–6 months in untreated and treated patients, respectively. Due to the location of metastatic lesions, surgical resection is limited, and chemotherapy is quite ineffective due to the blood brain barrier. It is thus crucial to identify patients at higher risk for brain metastasis at an early stage. Brain metastasis has been ascribed to the presence of subsets of circulating tumour cells (CTCs) that transmigrate through the blood brain barrier and thrive in the brain. No definitive signature genes for brain metastasis have been identified in CTCs from NSCLC due to the lack of validated markers or strategies to isolate these cells.

Application Deadline: 31 May 2024

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10.
Fully Funded PhD Position in Investigation the role of p62-dependent P-bodies in models of neurodegeneration

Summary of PhD Program:

This PhD project aims to investigate the link between p62 and ribonucleoprotein (RNP) granules, such as P-bodies, a dynamic category of membrane-less biomolecular assemblies consisting of RNAs and RNA binding proteins (RBPs) induced by multiple stimuli, including infection, oxidative and proteotoxic stress conditions. Aberrant formation of RNP granules is associated with several neurodegenerative diseases and we recently discovered the importance for p62-dependent P-body formation in regulating inflammatory responses (Barrow et al., 2024). In this project drosophila will be used as model organism for investigating the functionality of p62/RNP interactions in models of neurodegeneration in vivo, including AD and ALS. Furthermore, their role in driving a pro-inflammatory state that promotes neurodegeneration will be determined. 

Application Deadline: 31 May 2024

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