Are you holding PhD degree and looking for Postdoctoral Fellowships? Cold Spring Harbor Laboratory (CSHL), New York, USA invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.
1. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Zador lab has an opening for a postdoctoral fellow in neuroscience who will be part of the International Brain Laboratory (IBL). The IBL is a large-scale international collaboration in brain research, which combines the efforts of approximately 50 scientists in 22 laboratories toward understanding the brain-wide basis of a mouse visual decision-making task. The overall goal of this postdoc’s project will be to relate single neuron connectivity, gene expression and neural activity in the context of in the context of the IBL behavior, to better understand the contributions of different neuronal types to the IBL task. Specifically, the project will involve combining electrophysiological and imaging approaches (widefield and two-photon, including a mesoscope) with new approaches for high-throughput circuit/genomic approaches (including BARseq and MAPseq) developed in the Zador lab.
Application Deadline: Open Until Filled
2. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Yeh Laboratory at CSHL Cancer Center is looking for a postdoctoral fellow to carry out a new drug discovery project harnessing stapled peptide technology and diversity-oriented synthesis. The Yeh Lab is a highly-collaborative environment with state-of-the-art facilities and expertise in biotherapeutics engineering and chemical biology. The Yeh Lab also engages in several close collaborations with other research groups in CSHL. The postdoctoral fellow will enjoy the highly intellectual, cross-disciplinary and collaborative interactions at CSHL.
Application Deadline: Open Until Filled
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3. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Levy and Wigler research groups at Cold Spring Harbor Laboratory, NY are seeking independent and motivated researchers in Computational Biology and Bioinformatics. The successful candidate will have a key role in a multi-disciplinary team of wet-bench and computational researchers working to revolutionize cancer detection and treatment by developing novel genomic technologies. The candidate will work closely with bench scientists to draft the initial computational workflows to analyze new experimental data. Developing a relationship of feedback and understanding between the bench and the computer is essential to work of our groups. Rather than building a single pipeline to analyze a set of standardized data, our computational scientists routinely develop custom algorithms that shape the protocol development and design. For candidates eager to obtain cross-discipline experience, this position is an opportunity to learn from a group with substantial expertise in both computational and molecular biology.
Application Deadline: Open Until Filled
4. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A postdoctoral fellow position is available in the laboratory of Dr. Linda Van Aelst, Professor at Cold Spring Harbor Laboratory. The main focus of research will be to study the roles of genes associated with human diseases in the development and function of neural circuits, using molecular, genetic and viral engineering, optogenetics, imaging, electrophysiology, and behavior analysis.
Application Deadline: Open Until Filled
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5. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The protein phosphatases are critical, specific regulators of signaling that serve an essential function, in a coordinated manner with the protein kinases, to determine the response to a physiological stimulus. The Tonks Lab takes a multidisciplinary approach to study the structure, regulation and function of the protein tyrosine phosphatase (PTP) family of enzymes, to illustrate their fundamental importance to the control of signal transduction under normal and pathophysiological conditions. As functional studies have established links to disease, the PTPs have been garnering attention as potential therapeutic targets; however, they remain a largely untapped resource for drug development.
Application Deadline: Open Until Filled
6. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Tollkuhn Lab has an open position for a postdoctoral researcher to develop projects on hormonal regulation of brain sexual differentiation. The lab studies how gonadal hormones such as estrogen and testosterone regulate brain development, behavior, and disease. These hormones modulate the wiring of social behavior circuits during developmental sensitive periods to produce sex-variable behaviors in adulthood. Our lab is seeking a colleague with a background in neural development to explore how sex differences in gene expression give rise to sex-typical patterns of neuronal connectivity.
Application Deadline: Open Until Filled
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7. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Tollkuhn Lab has an open position for a postdoctoral researcher to develop projects on hormonal regulation of gene expression in the brain. The lab studies the transcriptional mechanisms of nuclear receptors in the context of brain development, behavior, and disease. Gonadal hormones such as estrogen and testosterone are the principal regulators of sex differences in the vertebrate brain, but the regulatory strategies used by hormone receptors in the brain remain largely unexplored. Our lab has recently published the first neural direct targets of estrogen receptor alpha (ER?), and we now seek a colleague with expertise in gene regulation and the epigenome, who can expand on this line of research.
Application Deadline: Open Until Filled
8. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A postdoctoral position in COMPUTATIONAL GENOMICS is available in Dr. Adam Siepel’s research group at the Simons Center for Quantitative Biology (SCQB), Cold Spring Harbor Laboratory. The Siepel Group specializes in the development of machine learning methods, probabilistic models, and application of these methods in large-scale genomic data analysis. Of particular interest is research relevant to existing NIH-supported projects in:
1. COMPARATIVE AND POPULATION GENOMICS including inference of ancestral recombination graphs, inference of selective sweeps, phylogenetics of mammals, and estimation of fitness consequences of new mutations; and
2. TRANSCRIPTIONAL REGULATION in mammals, including the estimation of rates and patterns of transcriptional elongation and promoter-proximal pausing from PRO-seq data.
Application Deadline: Open Until Filled
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9. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A post-doctoral position is available at the Schorn lab, Cold Spring Harbor Laboratory, NY. We are interested in how small RNAs identify and silence transposable elements when they become active during mammalian development and disease. We found that tRNA fragments (tRF) derived from the 3’-end of mature tRNAs are highly expressed in cells undergoing epigenetic reprogramming and target LTR-retroelements, or endogenous retroviruses (ERVs), at their conserved tRNA primer binding site (PBS). Due to the perfect sequence complementarity of 3’-tRFs to the PBS, they have tens of thousands of targets in mammalian genomes. 3’-tRFs are processed under yet unknown conditions and potentially protect many eukaryotes. This is an exciting new field with many opportunities! We believe tRFs are an ancient link between RNAi, transposons and genome stability.
Application Deadline: Open Until Filled
10. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A post-doctoral position in computational biology is available in David McCandlish’s group in the Simons Center for Quantitative Biology at Cold Spring Harbor Laboratory. Research in the McCandlish laboratory is focused on the analysis of high-throughput mutagenesis data, with the goal of accurately predicting the phenotypic, health, and evolutionary consequences of both single and multiple mutations in protein coding and regulatory sequences. The group has a particular emphasis on understanding complex genetic interactions and the structure of the genotype-phenotype map.
Application Deadline: Open Until Filled
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11. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Dr. Lingbo Zhang’s Laboratory at Cold Spring Harbor Laboratory (CSHL) is part of a $75 million Center for Therapeutics Research at CSHL. There are multiple fully funded postdoctoral fellowships available in the Zhang Laboratory to investigate roles of nervous system activities and micronutrients in regulating hematologic cancers and to develop novel therapeutic strategies for these diseases.
The Zhang Laboratory utilizes CRISPR functional genomics to systematically uncover critical genetic effectors and their related metabolites that modulate hematologic cancers. The ultimate goal is to understand how environmental signals such as nervous system activities and micronutrients modulate hematopoietic cell development and hematologic cancers. Based on these basic mechanistic insights, the Laboratory is building innovative therapeutics to treat hematopoietic cancers that are currently without effective therapeutic options.
Application Deadline: Open Until Filled
12. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Cold Spring Harbor Laboratory is looking for outstanding candidates to fill postdoctoral positions in theoretical neuroscience. The position is open under specific projects as well as general research involving the application of methods from theoretical physics, mathematics, and machine learning with the goal to understand the brain function.
Application Deadline: Open Until Filled
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13. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Koo Lab studies the functional impact of genomic mutations through a computational lens using data-driven machine learning solutions. We are broadly interested in applications for studying gene regulation and protein (dys)function. Our approach develops methods to interpret high-performing deep learning models to distill knowledge that they learn from big, noisy biological sequence data. Our goal is to elucidate biological mechanisms that underly sequence-function relationships, with a broader aim of advancing precision medicine for complex diseases, including cancer.
Application Deadline: Open Until Filled
14. Postdoctoral Position
Summary of Postdoctoral Fellowship:
We are currently seeking innovative, inventive, and self-driven Postdoctoral Associates within the lab of Dr. Leemor Joshua-Tor at Cold Spring Harbor Laboratory. The Joshua-Tor lab studies the structure and mechanism of gene silencing pathways as well as DNA replication. To get a complete understanding of how these processes, the team employs structural, biochemical, biophysical and molecular biology approaches to study how key proteins work at the molecular level.
Application Deadline: Open Until Filled
15. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Together, the Borniger, Lukey, and Janowitz laboratory at Cold Spring Harbor Laboratory (CSHL) offer a unique opportunity for a highly motivated and creative postdoctoral researcher, with strong experimental and analytical skills, to investigate the reciprocal interaction of sleep and cancer progression. You will become part of a multidisciplinary team of basic researchers and clinicians studying tumor-host interactions, using integrative techniques from neuroscience, endocrinology, metabolomics, and immunology to dissect the mechanisms connecting sleep disruption with aberrant metabolic and immune responses during cancer progression.
We are looking for candidates who will develop their own research questions in line with the overarching goals of this program. Substantial resources will be available to the selected candidate, including state-of-the-art laboratory space and the opportunity to discuss science in a diverse and supportive environment. Opportunities to develop skills in the use of murine models of cancer, advanced microscopy, optogenetics/chemogenetics, metabolomics, and biostatistics will be available.
Application Deadline: Open Until Filled
16. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Janowitz Laboratory at CSHL is seeking a highly motivated, creative, and interactive postdoctoral researcher with strong experimental and analytical skills to contribute to research on the connectivity of the host response to cancer. We employ pre-clinical and clinical research to develop and test new treatment strategies and to discover fundamental biological interactions between tumors and host organ systems.
We are looking for candidates interested in developing their own research question in alignment with the interests and skills present in the laboratory and institution. The selected candidate will be provided significant resources, including access to state-of-the-art laboratory space and the opportunity to discuss science in a relaxed and diverse atmosphere defined by constructive critical appraisal. Opportunities to learn about model systems of disease, advanced microscopy, genetic engineering, new sequencing techniques, bioinformatics, translational science, and statistical analyses will be provided.
Application Deadline: Open Until Filled
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17. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Furukawa lab has NIH-funded postdoctoral fellow/associate positions available for scientists interested in solving questions in neurobiology and neuro-cancer-immunology by implementing a dynamic range of techniques including structural biology (cryo-EM, x-ray crystallography, molecular dynamics) together with electrophysiology (patch-clamp, slice physiology, lipid bilayer), protein engineering, chemical biology, mouse model, cellular imaging, and cancer mouse model.
We have an excellent track record for unraveling detailed mechanisms and developing reagents for ligand-gated ion channels and will be conducting biological researches based on the gained molecular knowledge. CSHL is equipped with a Titan-KRIOS electron microscope/K3 direct electron detector and a Talos L120C screening microscope. It has an in-house x-ray generator/detector and convenient access to the NSLS-II synchrotron beamlines (AMX and FMX). CSHL has solid core facilities including high-performance computation (CPU/GPU), antibody production, cellular imaging, CRISPR/RNAi, single-cell sequencing, etc. We offer a unique training environment for research and career development.
Application Deadline: Open Until Filled
18. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A position is available for a postdoctoral researcher with a strong background in cancer biology and immunology. This postdoctoral fellow will be working under the directions of Dr. Gholami (an Associate Professor and surgeon scientist at Northwell Health) at Cold Spring Harbor Laboratory. The project will be focused on translational research studying the tumor microenvironment of colorectal cancer, with the overall goal of finding novel targeted and immune-augmenting combination therapies. The aims of the Project include developing and testing new treatment strategies, characterizing interactions between tumor and immune microenvironment, and elucidate mechanisms of response/resistance to therapies.
Application Deadline: Open Until Filled
19. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Cold Spring Harbor Laboratory invites applications for a Computational Post Doc in the laboratory of Dr. Alexander Dobin. The successful candidates will join a team of biological data scientists working on novel statistical methods and computational algorithms for multi-omics processing and integration, and leverage Big Genomic Data to elucidate various problems in precision health, such as genetic and epigenetic mechanisms of cancer development and progression, and clinical impact of functional variants.
Application Deadline: Open Until Filled
20. Postdoctoral Position
Summary of Postdoctoral Fellowship:
A postdoctoral position in computational neuroscience /machine learning is available in Dr. Benjamin Cowley’s research group at Cold Spring Harbor Laboratory, NY. We are looking for a computational postdoc broadly interested in using machine learning approaches to answer scientific questions about the brain. We focus on designing closed-loop methods for systems neuroscience as well as building explainable computational models of neural responses and behavior. An important component of our work is to build tight-knit collaborations with experimental neuroscientists—collecting data and building models in tandem. A long-term goal is to identify and understand the step-by-step computations in the brain.
Application Deadline: Open Until Filled
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21. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Cheadle Lab at Cold Spring Harbor Laboratory is inviting applications from highly motivated candidates for a postdoctoral position investigating interactions between neurons and non-neuronal cells (microglia and oligodendrocyte precursor cells [OPCs]) in the developing brain. We employ a multidisciplinary strategy to study these interactions that merges two-photon imaging in the brains of awake mice, single-cell genomics, and standard molecular and cell biological approaches. We seek an enthusiastic and independent lab member to lead a high-impact project focused on defining the mechanisms underlying glial cell function in mouse and human brains. Candidates from marginalized and/or excluded backgrounds, broadly defined, are strongly encouraged to apply.
Application Deadline: Open Until Filled
