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21 Postdoctoral Fellowships at University of Pennsylvania, Pennsylvania, USA

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Are you holding PhD degree and looking for Postdoctoral Fellowships? University of Pennsylvania, Pennsylvania, USA invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.

1. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Seeking a talented and highly motivated postdoctoral fellow to collaborate on research aimed at reducing the burden of breast cancer, particularly for racial/ethnic minorities, through precision prevention approaches. The postdoctoral fellow will work under the direct supervision of Dr. Anne Marie McCarthy, a cancer epidemiologist at the University of Pennsylvania Perelman School of Medicine in the Department of Epidemiology, Biostatistics, and Informatics. Projects will cover topic areas including breast cancer risk prediction, integration of genetics into breast cancer prevention, evaluation of novel imaging biomarkers of breast cancer risk, personalized screening, and racial disparities in breast cancer. Flexible start date.

Application Deadline: Open Until Filled

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2. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Conn Lab is looking for 1-2 postdocs focused on post-transcriptional gene regulation and the roles of RNA-binding proteins, RNA modifications, and signaling that are rewired during cancer progression. One project is focused on identifying regulators of selective translation and spatial RNA interactions in the cell during drug resistance in prostate cancer (more mechanism to move into translational research later). The other project is looking at adaptive stress responses in pancreatic tumors and will require mouse modeling, tissue analysis, and treatments in vivo. The lab has received two awards, over 3 years of DoD funding for project one and has independent funds for project two.

Application Deadline: Open Until Filled

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3. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Mark Kahn lab in the Perelman School of Medicine (Cardiology) is currently recruiting for a postdoctoral researcher for a grant funded project investigating myxomatous valve disease and the role of flow-responsive signals KLF2 and KLF4 in heart development. The Kahn lab uses complex mouse genetics systems with state-of-the-art biochemical and molecular approaches to understand the novel links between hemodynamic forces and vascular diseases in the arterial and venous system. We have collaborations across Penn, CHOP, and other academic institutions such as Duke, University of Chicago, and Cornell. The candidate should have experience with animal models, generation of transgenic alleles, possess strong molecular biology skills and a desire to explore new technologies including single cell analysis and advanced genetics.

Application Deadline: Open Until Filled

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4. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Seeking a talented and highly motivated postdoctoral fellow to collaborate on research aimed at creating innovative solutions for improving cancer screening and care. The postdoctoral fellow will work under the direct supervision of Dr. Katharine Rendle, a cancer implementation scientist at the University of Pennsylvania Perelman School of Medicine in the Department of Family Medicine & Community Health and Deputy Director of the Penn Center for Cancer Care Innovation. Potential projects cover range of topic areas including lung and cervical cancer screening, global disparities in cancer care, mixed methods research, clinical epidemiological, and evaluation of large-scale pragmatic trials. Summer 2023 Start Date (with some flexibility).

Application Deadline: Open Until Filled

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5. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are seeking a Postdoctoral Researcher with computational background who is interested in being an integral member of an interdisciplinary program across human and model systems genetics. The Postdoctoral Researcher’s work will focus on human genetics, statistical genetics, and phenotype data. Specifically, the Postdoctoral Researcher will employ bioinformatic approaches, including machine learning and innovative statistical methods, on whole genome sequence and quantitative phenotypic data to discern novel genotype-phenotype relationships in autism.

Applicants are expected to have experience with coding, bioinformatic/computational approaches and genomic analysis. The researcher may also assist in the analysis of clinical trial data. The candidate will work closely with ASPE principal investigators and leadership team to develop a rigorous and cutting-edge research agenda that prepares the Postdoctoral Researcher for his/her next career steps. Joining ASPE affords you with a unique cross-disciplinary training experience in collaborative science and access to a wide range of professional development activities.

Application Deadline: Open Until Filled

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6. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our lab at The University of Pennsylvania is seeking an enthusiastic, dedicated, and highly motivated Postdoctoral Researcher to serve in a leadership role in managing the Translational Neurosurgical Oncology Lab under the direction of Dr. Christina Jackson with the goal of understanding mechanisms of immune evasion by primary malignant brain tumors and skull base tumors to generate novel immune-based therapies. The senior research investigator will play a leading role in developing a research program in the advancement of our research pursuit and will play a crucial role both in all aspects of research products including development, implementation, and data analysis.

Application Deadline: Open Until Filled

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7. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Researcher position is available for a highly motivated applicant in the laboratory of Dr. Fiona Simpkins at the University of Pennsylvania. Our focuses are to understand resistance mechanisms to targeted therapies such as DNA Damage Repair inhibitors (DDRi), to sequence DDRi with Immuno-Oncology (IO) drugs, and to identify biomarkers or response to these agents. We have developed a preclinical drug development program in the Ovarian Cancer Research Center with the goal of moving novel laboratory therapeutic discoveries into the clinic. We have developed >150 patient derived xenografts (PDX) models, patient-derived organoids, and primary tumor cultures from ovarian and endometrial cancers. These PDX models mimic the original tumors, thereby accelerating the translation of preclinical study results into clinical trials for patients.

Application Deadline: Open Until Filled

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8. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral position is immediately available in the laboratory of Dr. Alessandra Chesi at the University of Pennsylvania with a focus on discovering and functionally characterizing novel genes for Alzheimer’s, Parkinson’s and other neurodegenerative diseases in human brain relevant cell types. Dr. Chesi has a long-standing interest in genomics and neurodegenerative diseases; she has developed Capture C based approaches to map GWAS signals to their effector genes (see some examples in linked publications) and is applying them to brain-related disorders. Main areas of research in our lab are 3D genomics and epigenomics techniques (such as Hi-C, ATAC-seq, ChIP-seq and RNA-seq), CRISPR/Cas9 editing, pooled CRISPRi/a screens with scRNA-seq readout, plus development of iPSC-based models for neurodegenerative and neurodevelopmental diseases (2D neuronal/glial differentiation, co-cultures, 3D brain organoids).

Application Deadline: Open Until Filled

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9. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Wilson laboratory in the Division of Diagnostic Innovation in the Department of Pathology and Laboratory Medicine at Penn is hiring a postdoctoral fellow to work on an established project focused on single cell and spatial analysis of human diabetic kidney disease. This position involves both dry lab and wet lab responsibilities and will consider applicants with experience in either area. The fellow will conduct single cell analysis of human donor specimens from patients with diabetic kidney disease under the supervision of Dr. Wilson. We have already sequenced a large number of single cell libraries in collaboration with Novo Nordisk and preprocessed our dataset for downstream analysis. We are looking for a motivated individual who can work together with our research team to complete any necessary validation studies and move this project to publication. Prior coding experience is not required and the position can be tailored to the applicant skillset.

Application Deadline: Open Until Filled

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10. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral researcher position is available in the Department of Psychiatry, University of Pennsylvania. The selected applicant will work under the direct supervision of Dr. Rachel Kember, a computational geneticist with expertise in biomedical informatics and psychiatric disorders. The postdoc will also have the opportunity to work with collaborators both at Penn and other institutions on multiple studies involving large-scale datasets. Current projects in the lab focus on understanding the genetic underpinnings of psychiatric and substance use disorders using genetic and phenotypic data from electronic health records with linked biobanks.

Datasets include the Million Veteran Program, a large dataset of over 850,000 veterans with genetic data currently available for 650,000 individuals; the Penn Medicine Biobank, which includes 190,000 patients, 45,000 with genetic data; and the Yale-Penn study, which includes 12,000 individuals with an in-depth substance use and psychiatric assessment. Dr. Kember is co-chair of the PsycheMERGE Diversity Initiative, a collaboration across multiple biobanks formed to address inequity in psychiatric genetics research.

Application Deadline: Open Until Filled

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11. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Applications will be reviewed as they arrive, starting immediately, and will be accepted until the position is filled. For full consideration, we recommend that you apply early. The Penn Computer Assisted Surgery and Outcomes (PCASO) Laboratory within Penn Surgery and the General Robotics, Automation, Sensing and Perception (GRASP) Laboratory at the University of Pennsylvania invites applications for a full-time postdoc opening.

This postdoc will conduct research to develop the next generation of surgical data science algorithms including context awareness, scene understanding, workflow analysis, sim2real transfer, performance assessment, and lifelong learning. The postdoc will also collaborate with other researchers to apply these algorithms to robotic surgery, laparoscopy, flexible endoscopy, and trauma surgery.

Application Deadline: Open Until Filled

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12. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A one year post doctoral fellowship is available immediately with the option to extend an additional 1-3 years, to investigate the role of the extracellular matrix protein type III collagen (Col3) in modulation of the breast cancer microenvironment. Using a combination of in vitro and mouse models, we have initiated multiple lines of investigation that will provide insight into how Col3 inhibits formation of a tumor-permissive microenvironment. This work also capitalizes on our studies using spontaneous naturally occurring large animal models of mammary tumors. Future work will characterize drivers of tumor-permissive and suppressive collagen signatures and investigate the use of a novel tissue engineering strategy to control tumor growth and metastasis following tumor resection to improve clinical outcome in veterinary and human breast cancer patients.

Application Deadline: Open Until Filled

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13. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Laboratory for Imaging Physics, Analysis, and Clinical translation (IMPACT) is seeking highly motivated individuals to join a number of NIH-funded projects. The IMPACT Lab is directed by Dr. Grace J. Gang and is located in the Department Radiology at the University of Pennsylvania. Our lab is dedicated to developing novel imaging technologies guided by a rigorous understanding of imaging science. Projects in the lab contain a mix of theoretical image chain modeling, benchtop experimentation, and technology integration on clinical imaging system.

Application Deadline: Open Until Filled

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14. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral position in cellular therapies for solid cancer is available immediately. The postdoc will investigate novel cellular therapies using gamma delta CAR-T cells for solid tumors using state-of-the-art technologies at the University of Pennsylvania. Training will be provided.

Application Deadline: Open Until Filled

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15. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Applications are invited for a postdoctoral position in the laboratory of Dr. Daniel J. Rader at the Perelman School of Medicine (PSOM) of the University of Pennsylvania. This position offers an opportunity to work in a highly collaborative, multidisciplinary research environment focusing on the human genetics of cardiometabolic traits and diseases, the elucidation of novel molecular and physiological mechanisms underlying these phenotypes, and new approaches to therapeutic interventions based on this knowledge. Approaches to this work may include computational genomics, cell-based and/or mouse model systems, protein structure-function relationships, characterizing the functional effects of naturally-occurring coding variants, and human-based mechanistic studies.

Application Deadline: Open Until Filled

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16. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Katona Lab invites applications for a post-doctoral position in the Gastrointestinal Cancer Genetics Program, which is part of the Division of Gastroenterology within the Perelman School of Medicine at the University of Pennsylvania. The Katona Lab is an exciting, highly collaborative, and interdisciplinary research program focused on gastrointestinal cancer and hereditary gastrointestinal cancer predisposition syndromes. Ongoing research activities in our group uniquely span the spectrum of basic science, translation studies, and clinical studies, and involve active collaborations across the Perelman School of Medicine, Abramson Cancer Center, the University of Pennsylvania, and external institutions.

Application Deadline: Open Until Filled

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17. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Researcher position is available in the laboratory of Dr. Jianxin You at the University of Pennsylvania Perelman School of Medicine. The laboratory investigates how the molecular interplay between oncogenic viruses and their host cells leads to cancer (Cell 117:349-360, Cell Host Microbe 19:775-87). We are also developing nanotechnology-based immunotherapy for eliciting antiviral and antitumor immunity against human cancers induced by tumor viruses (Proc Natl Acad Sci U S A. 2020;117:13730-13739).

Application Deadline: Open Until Filled

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18. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Qualified candidates will have demonstrated expertise as in one or more of the following disciplines: cancer biology, cancer metabolism, or chromatin biology. Expertise must be demonstrated through acquisition of a Ph.D. in one of these fields and through the publication (or impending publication) of peer reviewed manuscripts in reputable journals. Candidates should have a strong background in mouse modeling and molecular genetics. Foundational skills in computational genomic analysis is highly desired.

Application Deadline: Open Until Filled

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19. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Feldser Lab is looking for a postdoc to study the cell and molecular requirements for PKC signaling during Kras-mediated tumor initiation. The lab has received NIH funding for a 5 year project to begin immediately. The applicant should have demonstrated expertise in mouse modeling and tissue analysis including microscopy and immune staining techniques. Experience with flow cytometry and cell culture is required. The fellow will be expected to provide mentorship to technicians and students as needed.

Application Deadline: Open Until Filled

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20. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Bowman Laboratory is seeking to fill a postdoctoral fellow position to study clonal evolution in leukemia. Applicants with a recent PhD or MD/PhD with experience in animal modeling of disease or computational modeling of system dynamics are invited to apply. Interested applicants should forward their cover letter and CV to: robert.bowman@pennmedicine.upenn.edu

Application Deadline: Open Until Filled

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21. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Two postdoctoral researcher positions are available in the laboratory of Dr. Xiaolu Yang at the Perelman School of Medicine at the University of Pennsylvania. The Yang lab studies cancer and neurodegenerative diseases. Our current projects focus on two broad areas:

(1) The tumor suppressor p53, metabolism, and autophagy. We are interested in the regulation and functions of the preeminent tumor suppressor p53. Our results have revealed a role for p53 in modulating metabolic pathways that are critical for biosynthesis and redox balance. We are investigating the function of p53 as both a sentinel and a regulator for metabolic activities. We are also identifying and characterizing metabolic alterations that drive tumor initiation and progression. A recent extension of this research area is to define the role of metabolism and autophagy in stem cells, including embryonic stem cells and cancer stem cells.

(2) Protein quality control, aging, and neurodegeneration. Our lab recently identified two protein quality control (PQC) systems, which consist of tripartite motif (TRIM) proteins and poly-Asp/Glu (polyD/E) proteins, respectively. Unlike canonical PQC systems, these new systems are independent of ATP and are unique for animals (the TRIM system) or eukaryotes (the polyD/E system). Both systems are multifunctional and highly effective. We are investigating their mechanisms of action; their roles in aging and neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis; and their utility in treating these diseases.

Application Deadline: Open Until Filled

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