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19 Postdoctoral Fellowships at City of Hope, Duarte, California

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Are you holding PhD degree and looking for Postdoctoral Fellowships? City of Hope, Duarte, California invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.

1. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. David Chen’s lab in Systems Biology is seeking a highly skilled and motivated Staff Scientist or Postdoctoral Fellow to join their dynamic team. Dr. Chen is a distinguished leader serving as the Director of the Division of Epigenetics and Transcriptional Engineering at City of Hope Cancer Center. His lab investigates epigenetic mechanisms of drug resistance and identifies therapeutic targets in various cancers through cutting-edge techniques such as high-throughput genetic screens (recent papers: PMID: 38316881, 38394203, 37075745, 36563143, 34373586, 34210975). 

Application Deadline: Open Until Filled

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2. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Angelo Cardoso is looking for a talented and highly motivated Postdoctoral Fellow to join the Laboratory for Cellular Medicine, Center for Gene Therapy. You will join a well-established group performing cutting-edge research, development and qualification of large-scale processes, and manufacture of products for gene therapy clinical trials, including first-in-human studies with genetically engineered hematopoietic stem and progenitor cells (HSPC) and T cells.

Application Deadline: Open Until Filled

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3. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Join Dr. Marcel van den Brink’s multidisciplinary team to explore innovative ways to treat malignancies using engineered cellular therapies. We are looking for a highly motivated candidate with a PhD and/or MD degree interested in combining novel rational and combinatorial synthetic biology approaches with computational methods to develop strategies to improve CAR T cell activity. We aim to develop and mechanistically study novel cellular therapies with the goal of clinical translation.

Application Deadline: Open Until Filled

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4. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Reijonen’s research is focused on characterization of autoimmune-mediated Type 1 Diabetes. The lab seeks to identify autoreactive T lymphocytes in the blood of individuals with T1D and to understand the specific features of these cells, how they are activated and how they can be regulated. In this regard, the primary goal of this research is to discover novel “signatures” of autoreactive T cells and pathways leading to autoimmunity. The lab also focuses on extracellular vesicles as a means of communication between immune cells and pancreatic islets. The insights gained are employed to enhance disease prediction and monitoring and evaluate effectiveness of therapy.

Application Deadline: Open Until Filled

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5. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The selected candidate will have the opportunity of addressing ambitious research questions in areas such as in vitro/vivo characterization of driver genetic lesions in high-risk leukemia subtypes, multi-omics (WGS/WES, RNA-seq, ChIP-seq, CUT&Tag, ATAC-seq, etc.) analysis of the biological mechanisms underlying each leukemia, single-cell level leukemogenesis and micro-environment modeling in knock-in and xenograft mouse models, etc. We offer a top-notch research environment with ideas, projects, resources, infrastructure, collaborations, and mindset for innovative research.

Application Deadline: Open Until Filled

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6. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The laboratories of Drs. Bin (Amber) Zhang and Guido Marcucci in the Department of Hematological Malignancies and Translational Sciences are looking for highly motivated and creative Postdoctoral Fellow. You will join a well-established group focused on conducting and completing projects leading to publications in high-impact journals. Our labs have been focused on exploring the molecular mechanisms of leukemogenesis and evolution, discovery of novel therapeutic targets, and development of novel therapeutic strategies, including novel antibodies and CART cells, in acute myeloid leukemia (AML), chronic myeloid leukemia (CML), and acute lymphoblastic leukemia (ALL).

Application Deadline: Open Until Filled

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7. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A full-time postdoctoral position is available in Dr. Yun Rose Li’s laboratory. Dr. Li, a physician-scientist in radiation oncology, leads research that integrates genetic epidemiology, advanced sequencing, and bioinformatics technologies—including single-cell and spatial transcriptomics—with molecular biology approaches using cell-based and animal models. Her work also involves biomarker studies from clinical trials to understand the role of metabolic dysfunction in cancer risk and treatment response.

Application Deadline: Open Until Filled

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8. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Join Dr. Marcel van den Brink’s multidisciplinary team to explore innovative ways to decipher the molecular mechanisms of thymic regeneration. We are looking for a highly motivated candidate with a PhD and/or MD degree interested in using novel biological and computational methods with the aim of developing novel strategies to improve CAR T cell therapies and thymic function, spanning basic science to clinical trials. 

Application Deadline: Open Until Filled

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9. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are seeking a talented and motivated Postdoctoral Fellow within the multidisciplinary research team headed by Dr. Ajay Goel, Professor and Chair, Department of Molecular Diagnostics and Experimental Therapeutics and Associate Director of Basic Sciences, City of Hope Comprehensive Cancer. Our research group comprises of basic biologists, gastroenterologists, surgeons, medical oncologists and bioinformaticians, undertaking a number of collaborative projects involving large international consortia.

Application Deadline: Open Until Filled

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10. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Join Dr. Marcel van den Brink’s multidisciplinary team to explore innovative ways to decipher the molecular mechanisms by which the microbiome contributes to the biology of bone marrow transplantation. We are looking for a highly motivated candidate with a PhD and/or MD degree interested in using novel biological and computational methods with the aim of developing novel strategies to improve bone marrow transplantation and CAR T cell therapies, spanning basic science to clinical trials.

Application Deadline: Open Until Filled

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11. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Investigating the biological mechanisms underlying tumor progression: We use single-cell and bulk multiomic techniques to profile tumor samples, focusing on resistance mechanisms in breast cancer, glioblastomas, colon cancer, and lung cancer.
Advancing precision oncology through machine-learning models: We integrate multimodal patient data, including multiomic data and health record information, to develop predictive models for drug response. Furthermore, we work on creating new treatment stratification methods to personalize treatment for individual patients.

Application Deadline: Open Until Filled

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12. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The laboratory of Dr. Jianjun Chen is in search of a talented postdoctoral fellow. Our group is interested in discovering novel genetic and epigenetic regulations and deciphering their underlying molecular mechanisms in normal developmental processes and tumorigenesis. We cover research areas with relevance to Cancer Biology, Cancer Epigenetics, Epigenetics Regulation, Cancer Metabolism, Immunology, Drug Discovery, Development, and Structural Biology, with an emphasis on RNA epigenetics (RNA modifications) and DNA epigenetics (mainly focusing on the TET1/2/3-mediated DNA demethylation) associated basic and translational research. 

Application Deadline: Open Until Filled

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13. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Mingye Feng’s laboratory at the Beckman Research Institute of City of Hope is looking for a talented and highly motivated Postdoctoral Fellow. Dr. Feng is an awardee of the V Scholar Award from the V Foundation for Cancer Research, the Damon Runyon – Dale F. Frey Award for Breakthrough Scientists from the Damon Runyon Cancer Research Foundation, the K99/R00 Pathway to Independence Award from NIH, and NIH R01 grants. His laboratory employs cutting-edge techniques to understand mechanisms of macrophages in cancer immunosurveillance, identify immune checkpoints and ligands on various hematopoietic malignant and solider tumor cells with high-throughput screening and protein engineering approaches developed in the lab, and develop novel cancer immunotherapies targeting metastatic cancer cells. 

Application Deadline: Open Until Filled

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14. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are looking for a biomedical engineer, materials scientist, immunologist, or cancer biologist who can help us develop new minimally invasive cancer therapies, such as new materials or devices for drug delivery into tumors (percutaneous or intra-arterial). We are one of the few interventional oncology groups in the United States with a basic science lab, large animal tumor model, and several active clinical trials, which enables us to translate new discoveries from bench to animal to bedside.

Application Deadline: Open Until Filled

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15. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

If you are looking for a challenging and exciting opportunity to advance your research career in cancer and virology, we invite you to join Dr. Javier Gordon Ogembo’s multi-disciplinary lab. Our lab is part of the Beckman Research Institute of City of Hope, a world-renowned National Comprehensive Cancer Center located just 20 miles from Los Angeles. City of Hope provides access to state-of-the-art facilities and resources excellent for transitional science, as well as a vibrant and collaborative research community. The Beckman Research Institute of City of Hope has several facilities that are approved by the FDA for the production of investigational drugs and biologics for use in clinical trials.

Application Deadline: Open Until Filled

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16. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Karen Aboody M.D. lab is in search of a highly motivated postdoctoral fellow to develop and carry out stem cell studies involving targeted delivery of oncolytic virus to invasive cancers. This is a Translational Research Lab – we are involved with FDA IND-enabling and first-in-human clinical studies, as well as a biotechnology partnership.

Application Deadline: Open Until Filled

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17. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow is available in the lab of Dr. Rupangi Vasavada’s lab in the Department of Translational Research and Cellular Therapeutics in the Arthur Riggs-Diabetes and Metabolism Research Institute at City of Hope, CA. Research in the lab is highly translational focused on understanding the pathophysiology of diabetes and finding novel therapeutics through the identification of key biological pathways that enhance beta cell health, assessing the role of extracellular vesicles in disease pathology, and tapping their potential as early biomarkers. The lab employs a combination of cellular and molecular techniques, mouse models and patient samples for this research. Dr. Vasavada has NIH grants, JDRF clinical trial grant, philanthropy, and internal awards to support the research.

Application Deadline: Open Until Filled

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18. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow position in Computational Biology is immediately available under the direction of Dr. Nagarajan Vaidehi- Chair of Computational & Quantitative Medicine at the Beckman Research Institute. This project involves development and application of large-scale data analysis techniques from the Systems Biology field to molecular dynamics methods, and the study of the dynamics of G-protein coupled receptors complexes to understand its signaling selectivity. The project is inter-disciplinary and provides opportunities to train in large scale data analysis techniques as well as interact with experimental collaborators. City of Hope provides a multi-disciplinary collaborative environment with opportunities to interact with clinician scientists to conduct bench side to bedside research.

Application Deadline: Open Until Filled

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19. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The John Williams research lab at City of Hope is seeking a Postdoctoral Fellow or a Staff Scientist to join an innovative team. Our research primarily focuses on structural and biophysical methods to identify sources of energy additivity and multivalency in macromolecular complexes and use these properties to develop new tools and novel therapeutics.

Application Deadline: Open Until Filled

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