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18 Postdoctoral Fellowships at City of Hope, Duarte, California

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Are you holding PhD degree and looking for Postdoctoral Fellowships? City of Hope, Duarte, California invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.

1. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The laboratories of Drs. Bin (Amber) Zhang and Guido Marcucci in the Department of Hematological Malignancies and Translational Sciences are looking for highly motivated and creative Postdoctoral Fellow. You will join a well-established group focused on conducting and completing projects leading to publications in high-impact journals. Our labs have been focused on exploring the molecular mechanisms of leukemogenesis and evolution, discovery of novel therapeutic targets, and development of novel therapeutic strategies, including novel antibodies and CART cells, in acute myeloid leukemia (AML), chronic myeloid leukemia (CML), and acute lymphoblastic leukemia (ALL).

Application Deadline: Open Until Filled

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2. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Nath lab is seeking applicants for a postdoctoral position in computational cancer biology. Our lab aims to enhance cancer treatment outcomes through two main research areas:

Investigating the biological mechanisms underlying tumor progression: We use single-cell and bulk multiomic techniques to profile tumor samples, focusing on resistance mechanisms in breast cancer, glioblastomas, colon cancer, and lung cancer.

Advancing precision oncology through machine-learning models: We integrate multimodal patient data, including multiomic data and health record information, to develop predictive models for drug response. Furthermore, we work on creating new treatment stratification methods to personalize treatment for individual patients.

Application Deadline: Open Until Filled

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3. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Join Dr. Marcel van den Brink’s multidisciplinary team to explore innovative ways to treat malignancies using engineered cellular therapies. We are looking for a highly motivated candidate with a PhD and/or MD degree interested in combining novel rational and combinatorial synthetic biology approaches with computational methods to develop strategies to improve CAR T cell activity. We aim to develop and mechanistically study novel cellular therapies with the goal of clinical translation.

Application Deadline: Open Until Filled

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4. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The candidate will be working in a highly collaborative group on a research project on engineered anti-PSCA antibodies for immunoPET and targeted therapy of pancreatic cancer. This project offers unique multidisciplinary training in antibody engineering (design, production, purification and conjugation), molecular cancer biology, precision immuno-oncology, molecular imaging (immunoPET/CT) and translational research. Our research projects are supported by outstanding core facilities including Analytical Cytometry, Animal Resource Center, Mass Spectrometry and Proteomics, Pathology and the Small Animal Imaging Core (equipped with a PET/CT, 7T MRI/PET, and optical imaging instrumentation).

Application Deadline: Open Until Filled

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5. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The major ongoing projects are investigating miRNA biomarkers, pancreas pathology, and novel therapeutics, also in the context of the analysis of live pancreas tissue from organ donors obtained from the Network for Organ Donors with Diabetes (nPOD), of which Dr. Pugliese is Executive Co-Director, and in future clinical trials. Upcoming studies are projected to include the analysis of samples from patients with type 1 diabetes participating in clinical trials, with trials expected to start in late 2023 and 2024. Additional studies involve analysis of samples from recipients of pancreas-kidney transplant in the context of recurrent type 1 diabetes.

Application Deadline: Open Until Filled

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6. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Mingye Feng’s laboratory at the Beckman Research Institute of City of Hope is looking for a talented and highly motivated Postdoctoral Fellow. Dr. Feng is an awardee of the V Scholar Award from the V Foundation for Cancer Research, the Damon Runyon – Dale F. Frey Award for Breakthrough Scientists from the Damon Runyon Cancer Research Foundation, the K99/R00 Pathway to Independence Award from NIH, and NIH R01 grants. His laboratory employs cutting-edge techniques to understand mechanisms of macrophages in cancer immunosurveillance, identify immune checkpoints and ligands on various hematopoietic malignant and solider tumor cells with high-throughput screening and protein engineering approaches developed in the lab, and develop novel cancer immunotherapies targeting metastatic cancer cells. 

Application Deadline: Open Until Filled

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7. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Join Dr. Marcel van den Brink’s multidisciplinary team to explore innovative ways to decipher the molecular mechanisms by which the microbiome contributes to the biology of bone marrow transplantation. We are looking for a highly motivated candidate with a PhD and/or MD degree interested in using novel biological and computational methods with the aim of developing novel strategies to improve bone marrow transplantation and CAR T cell therapies, spanning basic science to clinical trials.

Application Deadline: Open Until Filled

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8. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We currently have a Postdoctoral Fellowship position in protein crystallography and drug discovery that is available as a joint position in the labs of Dr. Jianjun Chen, Chair of Department of Systems Biology and Deputy Director of Center for RNA Biology and Therapeutics, and Dr. Jeff Perry, Assistant Professor in the Department of Molecular Diagnostics and Experimental Therapeutics, at City of Hope Medical Center in Los Angeles, California. The research is focused on fragment – and small molecule-based drug discovery approaches against RNA/DNA epigenetic targets, RNA methylation and post-transcriptional regulation. 

Application Deadline: Open Until Filled

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9. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Angelo Cardoso is looking for a talented and highly motivated Postdoctoral Fellow to join the Laboratory for Cellular Medicine, Center for Gene Therapy. You will join a well-established group performing cutting-edge research, development and qualification of large-scale processes, and manufacture of products for gene therapy clinical trials, including first-in-human studies with genetically engineered hematopoietic stem and progenitor cells (HSPC) and T cells.

Application Deadline: Open Until Filled

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10. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our dynamic department stands at the forefront of cutting-edge medical research. As a Postdoctoral Fellow, you will actively contribute to groundbreaking projects, employing high-throughput CRISPR genetic screening to unveil novel targets and utilizing single-cell technology for in-depth genome analysis in hematological malignancies. You will also engage in diverse activities, from scrutinizing leukemia evolution to pioneering novel immunotherapies. Join our collaborative lab environment, where innovation and excellence fuel our quest for healthcare advancements tailored to hematological malignancy patients.

Application Deadline: Open Until Filled

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11. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. David Chen’s lab in Systems Biology is seeking a highly skilled and motivated Staff Scientist or Postdoctoral Fellow to join their dynamic team. Dr. Chen is a distinguished leader serving as the Director of the Division of Epigenetics and Transcriptional Engineering at City of Hope Cancer Center. His lab investigates epigenetic mechanisms of drug resistance and identifies therapeutic targets in various cancers through cutting-edge techniques such as high-throughput genetic screens (recent papers: PMID: 38316881, 38394203, 37075745, 36563143, 34373586, 34210975).

Application Deadline: Open Until Filled

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12. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Join Dr. Marcel van den Brink’s multidisciplinary team to explore innovative ways to decipher the molecular mechanisms of thymic regeneration. We are looking for a highly motivated candidate with a PhD and/or MD degree interested in using novel biological and computational methods with the aim of developing novel strategies to improve CAR T cell therapies and thymic function, spanning basic science to clinical trials. 

Application Deadline: Open Until Filled

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13. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Join Dr. Marcel van den Brink’s multidisciplinary team to explore innovative ways to treat malignancies using engineered cellular therapies. We are looking for a highly motivated candidate with a PhD and/or MD degree interested in combining novel rational and combinatorial synthetic biology approaches with computational methods to develop strategies to improve CAR T cell activity. We aim to develop and mechanistically study novel cellular therapies with the goal of clinical translation.

Application Deadline: Open Until Filled

More Details

 

14. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. Ya-Huei Kuo, in the Department of Hematologic Malignancies Translational Science. The research goals in the Kuo laboratory are to discover mechanisms of leukemogenesis and leukemia stem cell persistence; to develop mechanism-based targeted therapeutics; and to deliver useful tools to monitor and predict disease progression or therapy response. The laboratory utilizes genetic mouse models and patient-derived xenografts of leukemia combined with cell culture, biochemistry, functional genomics, high-throughput sequencing and mathematical modeling approaches.

Application Deadline: Open Until Filled

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15. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Reijonen’s research is focused on characterization of autoimmune-mediated Type 1 Diabetes. The lab seeks to identify autoreactive T lymphocytes in the blood of individuals with T1D and to understand the specific features of these cells, how they are activated and how they can be regulated. In this regard, the primary goal of this research is to discover novel “signatures” of autoreactive T cells and pathways leading to autoimmunity. The lab also focuses on extracellular vesicles as a means of communication between immune cells and pancreatic islets. The insights gained are employed to enhance disease prediction and monitoring and evaluate effectiveness of therapy.

Application Deadline: Open Until Filled

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16. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The selected candidate will have the opportunity of addressing ambitious research questions in areas such as in vitro/vivo characterization of driver genetic lesions in high-risk leukemia subtypes, multi-omics (WGS/WES, RNA-seq, ChIP-seq, CUT&Tag, ATAC-seq, etc.) analysis of the biological mechanisms underlying each leukemia, single-cell level leukemogenesis and micro-environment modeling in knock-in and xenograft mouse models, etc. We offer a top-notch research environment with ideas, projects, resources, infrastructure, collaborations, and mindset for innovative research.

Application Deadline: Open Until Filled

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17. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are looking for a biomedical engineer, materials scientist, immunologist, or cancer biologist who can help us develop new minimally invasive cancer therapies, such as new materials or devices for drug delivery into tumors (percutaneous or intra-arterial). We are one of the few interventional oncology groups in the United States with a basic science lab, large animal tumor model, and several active clinical trials, which enables us to translate new discoveries from bench to animal to bedside.

Application Deadline: Open Until Filled

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18. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

If you are looking for a challenging and exciting opportunity to advance your research career in cancer and virology, we invite you to join Dr. Javier Gordon Ogembo’s multi-disciplinary lab. Our lab is part of the Beckman Research Institute of City of Hope, a world-renowned National Comprehensive Cancer Center located just 20 miles from Los Angeles. City of Hope provides access to state-of-the-art facilities and resources excellent for transitional science, as well as a vibrant and collaborative research community. The Beckman Research Institute of City of Hope has several facilities that are approved by the FDA for the production of investigational drugs and biologics for use in clinical trials. 

Application Deadline: Open Until Filled

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