Cleveland Clinic, Ohio, USA invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.
1. Postdoctoral Position in innate immunity
Summary of Postdoctoral Fellowship:
The complement system is an important part of the innate immunity. Complement activation products not only directly help to eliminate invading pathogens, but also participate in many immunological reactions, including clearance of immune complexes, antibody production, and T-cell regulation. Insufficient or excess complement activation has been shown to be important in a wide range of disease states, such as multiple sclerosis, myasthenia gravis, systemic lupus erythematosus, rheumatoid arthritis, and age-related macular degeneration, as well as in allograft rejection.
Application Deadline: Open Until Filled
2. Postdoctoral Position in molecular biology
Summary of Postdoctoral Fellowship:
The post-doctoral fellow is expected to have a strong grounding in basic biochemistry and molecular biology and will have an interest and commitment to learning and mastering proteomics and degradomics experiments and translational applications to human disease.
Application Deadline: Open Until Filled
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3. Postdoctoral Position in in hematological malignancies
Summary of Postdoctoral Fellowship:
The overarching goal of our research program is to better understand the molecular and cellular mechanisms underlying disease progression and drug resistance in hematological malignancies. Our group is interested in studying oncogenic signaling pathways and metabolic reprogramming in hematological malignancies. We aim to uncover previously unrecognized vulnerabilities for therapeutic intervention. Our research involves multi-disciplinary approaches including molecular biology, biochemistry, chemical biology, immunology, mouse genetics and CRISPR-based gene editing.
Application Deadline: Open Until Filled
4. Postdoctoral Position in tumor immunology and microenvironment
Summary of Postdoctoral Fellowship:
We are interested in elucidating the tumor immunology and microenvironment leading to disease development and treatment response. Currently we are investigating the mechanisms by which a novel CD8+ T cell population discovered by our team mediates immunotherapy resistance, and are testing various therapy regimens targeting this T cell subset to improve responses to anti-PD-1 based therapy.
Application Deadline: Open Until Filled
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5. Postdoctoral Position in kidney diseases
Summary of Postdoctoral Fellowship:
Severe, progressive kidney diseases (CKD) are more common among Black patients than other populations. Variants in the APOL1 gene are strongly associated with excess kidney disease risk in African ancestral communities.
Application Deadline: Open Until Filled
6. Postdoctoral Position in Wellness and Preventive Medicine
Summary of Postdoctoral Fellowship:
The CRT has strong research mentorship, research grant administration, and project support staff as well as relationships with the Cleveland Clinic Center for Value Based Care Research, the Lerner Research Institute, and investigators across the Clinic’s specialty institutes. The successful fellow will receive comprehensive training and a unique research experience in integrative and functional medicine research from our multidisciplinary faculty.
Application Deadline: Open Until Filled
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7. Postdoctoral Position in Immunotherapy & Precision Immuno-Oncology
Summary of Postdoctoral Fellowship:
Immune-based therapies are redefining how cancer and other diseases are treated, helping to improve clinical outcomes for as many patients as possible. The Center for Immunotherapy & Precision Immuno-Oncology (CITI) at Cleveland Clinic’s Lerner Research Institute merges our expertise in immunology and genomics to drive innovation in research and care. We are a department that includes research laboratories, shared research platforms, developmental therapeutics and precision medicine programs.
Application Deadline: Open Until Filled
8. Postdoctoral Position in oral microbiota
Summary of Postdoctoral Fellowship:
The oral microbiota is emerging as an important driver of local and systemic disease. In the Apollo (Stacy) Lab, we decipher metabolic communication between the oral microbiota and host in the settings of gum disease (periodontitis) and oral cancer. In particular, we analyze how host-derived metabolites shape the ecological balance between commensals and pathogens, and how this balance in turns tunes host immune responses. We leverage an interdisciplinary approach involving bacterial genetics, genomics, animal models, immune profiling, and human samples. Our long-term goal is to translate host-derived metabolites into microbiota-directed therapies.
Application Deadline: Open Until Filled
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9. Postdoctoral Position in Brain Dynamics
Summary of Postdoctoral Fellowship:
The Brain Dynamics Laboratory seeks to investigate intracranial signals recorded from the human brain, using advanced neuroengineering methodologies to characterize the inherent dynamical transitions and network activity underscoring healthy and disease conditions. A particular focus is on epilepsy and the analysis of multimodal data, including multi-site spatiotemporal electrophysiological recordings collected in vivo, to develop and implement dynamics-based surgical decision-making.
Application Deadline: Open Until Filled
10. Postdoctoral Position in cancer and infection disease
Summary of Postdoctoral Fellowship:
The Xie lab at Lerner Research Institute at Cleveland Clinic is recruiting enthusiastic and motivated postdoctoral researchers to join us to study genome structure, dynamics and regulatory mechanisms in cancer and infection disease. We integrate cutting-edge super-resolution imaging (Xie et al., Nature Methods, 2020), live cell single molecule imaging (Xie et al., Genes & Development, 2017; Knight, Xie et al., Science, 2015) with modern genomics and genome engineering approaches to study the 4D architecture and dynamics of the mammalian genome (Xie et al., Mol.Sys.Bio, 2021) and the fundamental genome regulatory mechanisms in cancer evolution and infection diseases (King*, Yost*, Xie* et al., Nature, 2021).
Application Deadline: Open Until Filled
11. Postdoctoral Position in smooth muscle cell
Summary of Postdoctoral Fellowship:
Our lab is interested in molecular and cellular mechanisms responsible for smooth muscle cell (SMC) and endothelial cells (EC) phenotypic transitions. We use a combination of animal and cell culture models in combination with the bioinformatics analyses such as bulk and single cells RNA-sequencing to better understand these transitions, with the goal to develop novel therapeutic interventions for stabilizing atherosclerotic plaques in order to reduce the risk of plaque rupture with possible myocardial infarction or stroke.
Application Deadline: Open Until Filled
12. Postdoctoral Position in neurophysiology
Summary of Postdoctoral Fellowship:
The Laboratory for Bionic Integration is seeking a postdoctoral fellow with interest in exploring the mechanisms of multisensory integration and the proprioceptive sense of kinesthesia. The lab works at the dynamic and exciting intersection of advanced sensory-motor bionics, experimental neurophysiology, cognitive and perceptual integration, and the molecular basis of proprioception.
Application Deadline: Open Until Filled
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13. Postdoctoral Position in host defense against bacterial infection
Summary of Postdoctoral Fellowship:
We are looking for an individual interested in understanding mechanisms of host defense against bacterial infection and the consequences of dysfunctional defenses in the context of skin and intestinal disease. Research questions will be addressed in a variety of experimental systems ranging from primary cell culture, analysis of patient samples, to pre-clinical models of disease. An ideal candidate will have excellent organizational skills and an attention to detail, as well as enjoy working as part of a team.
Application Deadline: Open Until Filled
14. Postdoctoral Position in cancer treatment resistance
Summary of Postdoctoral Fellowship:
Looking for motivated team players who are interested in or have expertise in transcription regulation, kinase action, and the molecular mechanisms that drive cancer treatment resistance.
Application Deadline: Open Until Filled