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12 Postdoctoral Fellowships at Roswell Park Comprehensive Cancer Center, Buffalo, New York

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Are you holding PhD degree and looking for Postdoctoral Fellowships? Roswell Park Comprehensive Cancer Center, Buffalo, New York invites multiple online application for Postdoctoral Fellowships in various research areas. Candidates interested in Postdoctoral Fellowships can check the details and may apply as soon as possible.

1. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The laboratory of Dr. Marco Davila in the Department of Medicine is looking for a postdoctoral candidate to work on a research project aiming to generate novel chimeric antigen receptor (CAR) T cells specifically targeted to antigens for the treatment of cancer. The specific research project involves the usage and identification of antigens for targeted cell therapies, CAR design, and experimental models to validate antitumor capacity. The selected individual will perform studies using in vitro models to validate and enhance the ability of CAR T cells to be used as effective cell therapy.

Application Deadline: Open Until Filled

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2. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Liu lab (https://www.roswellpark.org/xuhang-liu) at the Department of Pharmacology and Therapeutics at Roswell Park Comprehensive Cancer Center is seeking highly-motivated postdoctoral fellows with interests in RNA and/or cancer biology to join our efforts in fighting cancer. We employ a multi-disciplinary approach that combines in vivo mouse models, in vitro patient-derived organoids (PDOs), classical biochemistry, cutting-edge multi-omics techniques, and advanced bioinformatic analyses to discover key post-transcriptional mechanisms that govern cancer progression and metastasis. 

Application Deadline: Open Until Filled

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3. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral position is available in the Atanassov Lab in the Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, New York. We are looking for a highly motivated, self-driven postdoctoral fellow to study the role of deubiquitinating enzymes (DUBs) in cancer. The postdoctoral fellow will work with a dynamic team of scientists and research fellows in an outstanding research environment and utilize genetically engineered mouse models and biochemical approaches to elucidate the molecular mechanisms of how DUB functions potentiate cancer growth and develop strategies for their therapeutic targeting. 

Application Deadline: Open Until Filled

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4. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Das lab at Roswell Park Comprehensive Cancer Center is looking for a highly motivated postdoctoral fellow with a passion for research to study molecular mechanisms of breast cancer with emphasis on the crosstalk between estrogen receptors and p53 signaling. Translating lab findings to novel therapies will be a priority (see Mukhopadhyay et al. Journal of the National Cancer Institute (JNCI) 2019, Oturkar et al. Cancers 2022, Scarpetti et al. The Oncologist 2023)

Application Deadline: Open Until Filled

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5. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our laboratory studies and develops adoptive T cell (CAR T cell) therapies targeting solid tumors. The postdoctoral scientist will develop genetically engineered T-cell therapies starting from the molecular cloning phase of cell therapy development, and then advancing to preclinical in vitro work and clinically relevant mouse models. A strong background in molecular biology and immunology will allow the successful applicant to be creative within the lab, enhancing T cell function and tumor targeting for optimal patient translation and high-impact publication.

Application Deadline: Open Until Filled

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6. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral position is open for a highly motivated candidate in the laboratory of Dr. Liya Ding in the Department of Immunology at Roswell Park Comprehensive Cancer Center. The laboratory’s research focuses on investigating the interactions between cancer cells and the host immune system during cancer development and progression. Employing a multidisciplinary approach, the laboratory utilizes ex vivo co-culture systems of tumor and immune cells, syngeneic and humanized mouse models, CRISPR screening, scRNA seq, spatial biology imaging and bioinformatics to identify critical regulators that contribute to the tumor immunosuppressive microenvironment during tumor progression, metastasis, and therapeutic resistance.

Application Deadline: Open Until Filled

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7. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Postdoctoral position is open for highly motivated candidates in the laboratory of Dr. Subhamoy Dasgupta, Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, NY – a National Cancer Institute (NCI) designated comprehensive cancer center. Some of the ongoing research directions in Dasgupta lab are:
(a) Discovering tumor metabolic adaptations that promote metastatic progression.
(b) Understanding the mechanisms regulating organ specific adaptation of tumors leading to metastatic colonization. Strong focus on bone-metastatic tumors.
(c) Deciphering epigenetic landscape of aggressive tumors and identifying how nutrient signaling and metabolism modulates histone acetylation/methylation impacting chromatin accessibility.
(d) Nuclear receptor and coactivator dependent transcriptional regulation of hormone-dependent tumors and defining the mechanisms driving therapeutic resistance.
(e) Interrogate the tumor-immune microenvironment and discover the mechanisms driving tumor-immune escape.

Application Deadline: Open Until Filled

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8. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Post-doctoral Associate position is now available in the Bio-behavioral Health and Recovery Laboratory led by Dr. Christine Sheffer at Roswell Park Comprehensive Cancer Center. The postdoctoral associate will contribute to NIH-funded research studies employing brain stimulation, behavioral economics, and neuro-economic approaches to address substance use, addiction, and health behaviors using both human laboratory and clinical trial methodologies.

Application Deadline: Open Until Filled

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9. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral position is open for a highly motivated candidate in the laboratory of Dr. Veena Prahlad, Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo NY. Roswell Park is a National Cancer Institute (NCI) designated Comprehensive Cancer Center. The broad research goals of the Prahlad lab are to understand the role of the nervous system in controlling the stress response pathways of other cells through neuroendocrine molecules and trophic interactions [Prahlad et al., Science 2008, Prahlad & Morimoto, PNAS 2011, Tatum et al., Current Biology 2015, Ooi and Prahlad, Science Signaling 2017, Das et al., eLife 2020, Das, Min and Prahlad, Mol. Cell 2021, Godthi, et al., PNAS 2024]. This question is relevant to the role of nerves in cancer and is integral for understanding several proteotoxic diseases.

Application Deadline: Open Until Filled

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10. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Postdoc positions are available immediately, in Dr. Dean Tang’s laboratory, to study NIH grant-supported projects that are centered on understanding prostate cancer cell heterogeneity/plasticity (Li Q et al., Nat. Commun. 2018; Zhang D et al., Nat. Commun. 2020; Kirk J. et al., Cell Stem Cell 2024) and the mechanisms of action of tumor suppressor LRIG1 (Li Q, et al., Nat. Commun. 10:5494, 2019; Ji Y. et al., Semin. Cancer Biol. 2022). The main ongoing projects include, among others: 1) investigating the tumor-suppressive functions of LRIG1 in novel genetic mouse models; 2) uncovering the novel LRIG1-interacting protein partners in both androgen-dependent and androgen-independent prostate cancers; 3) developing LRIG1-based biomarkers and therapeutics; and 4) elucidating the epigenetic underpinnings of treatment-induced plasticity in prostate cancer cells.

Application Deadline: Open Until Filled

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11. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral position is available in the Wilde lab in the Department of Urology, Roswell Park, an NCI-designated Comprehensive Cancer Center. The main goals of our lab are to 1) decipher the mechanisms by which metabolites regulate tumor initiation, and 2) identify metabolic liabilities of tumor initiation, especially in the context of hereditary cancers.

Application Deadline: Open Until Filled

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12. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The connection between Indigenous peoples and the natural environment has important ancestral, historical, cultural, and health related elements. The Roswell Park Center for Indigenous Cancer Research seeks a postdoc to collaborate in project(s) development across tribal areas dedicated to environment, human exposure and the human condition as they relate to cancer health issues and population science. We seek applications from a researcher who has worked and has experience with Indigenous populations, bench or basic science, cancer health disparities, and environmental research. 

Application Deadline: Open Until Filled

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