1. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Calico Life Sciences is recruiting a Postdoctoral Fellow to join our multidisciplinary protein science team with a focus on characterizing protein targets relevant to human aging and oncology. We seek a highly motivated individual who is passionate about pursuing basic research in the field of cellular signaling mediated by G protein-coupled receptors (GPCRs) on the cell surface. The successful candidate will play a key role in developing comprehensive approaches to unravel the complexities of GPCR signaling, including the investigation of how individual and dimerized GPCRs influence G proteins. We anticipate the successful candidate will work closely with computational modeling scientists, protein biochemists and structural biologists in the group.

Application Deadline: Open Until Filled

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2. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A full-time postdoctoral scholar position is available for a highly motivated scientist interested in biostatistical analysis and discrete choice measurement for healthcare and treatment-related outcomes and health economics research. The postdoctoral researcher will have the opportunity to assist with all aspects of a newly funded Department of Defense 4 year project. They will work within the UCSF Program for Pharmacoeconomics and Policy Studies (PRoPEPS) led by Dr. Leslie Wilson and in conjunction with Hangar Clinics Nationally, as well as with other research projects in PRoPEPS, but with a large focus on statistical analysis.. The goal is to better understand how to translate behavioral economics into clinical practice across a wide range of new technologies.

Application Deadline: Open Until Filled

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3. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoc research opportunity is available in the Drug Research Unit. The participant will conduct research on quantitative analysis of drugs including, but not limited to, antimalarials and antivirals using liquid chromatography-tandem mass spectrometry (LC-MS/MS) and other analytical methods. A current project (funded by NIH, 1R21 AI153848-01A1) is to explore two-dimensional liquid chromatography tandem mass spectrometry method to quantify unbound antimalarial drugs in human plasma. The participant may also involve in pharmacokinetic data analysis including non-compartment analysis using WinNonlin® or modeling study using NONMEM®. Under the guidance of the mentor/Unit Co-directors, the participant will learn about quantitative analytical method development and validations and complex pharmacokinetic data analysis.

Application Deadline: Open Until Filled

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4. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The research laboratory of Prof. Rada Savic in the Department of Bioengineering and Therapeutic Sciences at UCSF is engaged in groundbreaking drug development projects for Global Health including infectious diseases such as tuberculosis, HIV, and malaria, as well as pain management and autoimmune disease with a focus on identifying optimal treatment regimens. We develop and apply disease models, perform pharmacokinetic and pharmacodynamic evaluations, build physiology-based pharmacokinetic models, conduct exposure-response analyses, and utilize model-based simulations with the ultimate goal of optimizing treatment in adult, and pediatric and other special patient populations.

Application Deadline: Open Until Filled

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5. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We have a long-standing interest in elucidating the molecular mechanisms of lung development, repair/regeneration, and tumorigenesis. These studies aim to establish the foundation for treating human diseases such as chronic obstructive lung disease (COPD) and lung cancer. To this end, we use the mouse as a model system and also take advantage of normal and diseased human lung tissues. We combine mouse genetics, cell biology, genomic analysis, CRISPR technology, proteomics, and lung organoids to address central questions in alveolar formation and repair, and the pathogenesis of lung cancer development. Our research program holds the promise of translating discovery from bench to bedside.

Application Deadline: Open Until Filled

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6. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

D. E. Shaw Research develops and uses advanced computational technologies to understand the behavior of biologically and pharmaceutically significant molecules at an atomic level of detail, and to design precisely targeted, highly selective drugs for the treatment of various diseases. Among our core technologies is a proprietary special-purpose supercomputer called ANTON® which we designed and constructed to perform molecular dynamics simulations more than 100 times faster than the world’s fastest general-purpose supercomputers. DESRES develops and refines advanced biomolecular modeling methods, software, and machine learning techniques on ANTON®, as well as on general-purpose supercomputers, in order to pursue both internal and collaborative drug discovery programs.

Application Deadline: Open Until Filled

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7. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Northern California Institute for Research and Education (NCIRE) is the leading nonprofit research institute in the United States devoted to advancing Veterans health research. NCIRE is part of one of the world’s most dedicated and successful Veterans care communities, pioneering new treatments and understandings of military medicine and care. Along with our partners at the San Francisco VA Health Care System and the University of California, San Francisco, we are working to discover and develop effective, safe, and practical treatments for military injuries and diseases affecting Veterans. Through new technologies, novel scientific insights, and international clinical collaborations, we strive to set a new standard of health care research for Veterans and military personnel.

Application Deadline: Open Until Filled

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8. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Cardiac Biomechanics Lab at San Francisco VA Medical Center and UCSF is seeking a highly motivated and skilled Postdoctoral Fellow to join our team. The successful candidate will work on an experimental study of aortic tissue material properties, with a focus on conducting biaxial stretching experiments to understand the mechanical behavior of the aortic wall under various physiological and pathological conditions.

Application Deadline: Open Until Filled

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9. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Ellerby lab at the Buck Institute is seeking a Postdoctoral Scientist to model neurodegenerative diseases- Alzheimer’s , Huntington’s disease or X-Linked Dystonia Parkinsonism – using iPSCs. The successful candidate will have some experience in stem cell biology, neurodegenerative diseases, and use of mouse models of disease. They will have a demonstrated aptitude to be a leading author on peer-reviewed publications, provide innovative solutions to research problems, and can apply for fellowship/scholarship awards. This work is in collaboration with the Campisi, Melov or Schilling labs.

Application Deadline: Open Until Filled

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10. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Better Lab at UCSF is seeking a dedicated postdoctoral researcher who is interested in the intersections between healthcare delivery, human-centered design and health equity. We are a small team of faculty and staff, centered at the Zuckerberg San Francisco General Hospital, who are passionate about using human-centered design and other innovative approaches in order to meaningfully improve healthcare delivery for underserved populations. This position provides a unique opportunity to help develop and grow the discipline of human-centered design in academic medicine and to improve health care services, systems, and products for vulnerable populations domestically and internationally. This is an academic position at UCSF and comes with opportunities for professional advancement and promotion.

Application Deadline: Open Until Filled

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11. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A full-time postdoctoral scholar position is available for a highly motivated scientist interested in biostatistical and machine learning predictive modeling for healthcare and treatment-related outcomes and health economics research. The postdoctoral researcher will have the opportunity to lead statistical analyses working with large administrative and medical record datasets and will work with the UCSF Medication Outcomes Center (MOC) director Dr. Rodriguez-Monguio and her team to generate new statistical and modeling approaches to better understanding health outcomes in older patients with Alzheimer disease and related dementias. The fellow will have opportunities to publish the work in professional journals and/or present data at professional meetings.

Application Deadline: Open Until Filled

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12. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Ashouri Lab has an opening for a postdoctoral researcher who is interested in understanding how immune tolerance is bypassed in autoimmune diseases. Our lab is focused on advancing our knowledge of T cell signaling and repertoire thresholds required for immune tolerance. We study how the complex molecular interactions between cells alter immune health and the impact dysregulation in these communication pathways has on immune mediated diseases, such as rheumatoid arthritis. We utilize mouse models, human samples, along with molecular, cell-based, genetic, and multi-omic technologies including paired single-cell RNA and TCR-sequencing, and genetic engineering of primary immune cells. A major driving force of the lab is to identify the TCR specificities, gene expression profile, and signaling networks of cells involved in antigen recognition in autoimmune diseases.

Application Deadline: Open Until Filled

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13. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We believe that the single most important aspect of a health policy fellowship is the experience of designing and conducting research projects under the guidance of a dedicated and outstanding mentor. We begin the process of identifying suitable research mentors for each candidate during the application and interview process and make every effort to connect each candidate with a variety of faculty members with similar interests and expertise. We place great emphasis on finding a good match between the fellow and the mentor that includes a common research interest as well as a complementary style that will foster the most productive working relationship.

Application Deadline: Open Until Filled

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14. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Postdoctoral position is available to study the genomics and OMICs of recurrent pregnancy loss. The candidate will participate in the recruitment of clinical cases, collaboration with other clinics, whole genome sequencing, single cell sequencing, environmental exposures and data interpretation and incorporation with metabolomics measurements. The goal is to primarily understand genomic determinants and develop molecular signatures that predict pregnancy loss.

Application Deadline: Open Until Filled

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15. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Pfizer’s Cell Line Development (CLD) organization is seeking a highly motivated and highly qualified postdoctoral fellow to develop technologies that enhance RNA-based modalities. The postdoctoral fellow will have the opportunity to perform platform technology development activities that are critical to advance Pfizer’s biotherapeutics pipeline toward clinical and commercial development. This role requires expertise in molecular biology/biochemistry with an emphasis on RNA biology/biochemistry, including in vitro transcription reactions.

Application Deadline: Open Until Filled

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16. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The immuno-oncology group is looking for an exceptionally trained immunologist to join the Powell Lab. The selected candidate will design, create, and conduct innovative approaches to identify critical and novel regulators involved in T cell differentiation during acute infection and cancer with also applications to immune system dysfunction that is found during aging. This position presents a unique opportunity to work alongside scientists with a broad range of expertise at the intersection of basic and translational biology. The candidate will also heavily collaborate across various scientific disciplines to gain new and meaningful insights that can also be studied in immune cells.

Application Deadline: Open Until Filled

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17. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Calico invites outstanding early-career scientists to apply for a postdoc position in the Gillich Lab. Our lab is using genetic and single-cell approaches to elucidate the programs governing the maintenance and repair of the lung and what goes wrong with these programs during aging and in age-associated diseases. We are seeking a creative, ambitious, and highly motivated individual to join our team. You will employ cutting-edge microscopy and genomic approaches in mouse and human tissues to investigate how the structure, function and cells of the lung and vasculature are maintained in homeostasis and how they are altered during aging.

Application Deadline: Open Until Filled

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18. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Calico is seeking a talented scientist with lab-bench and computational skills to lead an interdisciplinary effort bridging the Gottschling lab and Discovery Data Science team to address the questions above and ultimately building a predictive model of the mechanisms associated with aging-transitions. The aforementioned technologies can be used to generate novel datasets and test predictions in an iterative process.

Application Deadline: Open Until Filled

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19. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Huang Lab at UCSF is recruiting postdoctoral fellows to lead projects that will utilize and develop single cell genomics and other molecular approaches to study mechanisms of carcinogenesis, with a focus in genitourinary malignancies. This position will be supported by an NIH-funded Program, which aims to leverage genomic technologies, organoids, and CRISPR/Cas9 genome engineering to understand the role that mutations play in cancer cells. Fellows will also gain experience with multi-omic approaches and analyses.

Application Deadline: Open Until Filled

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The post 19 Postdoctoral Fellowships at University of California San Francisco, California appeared first on FellowshipBard.

1. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Do you want to put your basic biochemistry and cell biology knowledge into action, and see your research translate into the clinic? The Chou Lab at the University of California, San Francisco is seeking to recruit an outstanding candidate to fill a Postdoctoral Fellow position. Research in the lab focuses on (1) understanding the molecular drivers of genitourinary malignancies, including prostate and bladder cancers; (2) investigating the mechanisms that contribute to disease progression, drug resistance and metastasis, including the role of the tumor immune microenvironment; and (3) developing novel therapies for genitourinary cancers.

We are particularly interested in discovering novel surface protein targeting strategies and identifying new synthetic lethalities for specific molecular subtypes of cancer. Our lab utilizes cancer cell biology, immunology, CRISPR screening, mouse modeling and genomic approaches to answer these questions.

Our goal is to translate discoveries from the lab into the clinic to benefit oncology patients, and take questions from the clinic and answer them in the lab. We work collaboratively with basic scientists, radiologists, chemists, computational biologists, pathologists, surgical oncologists, radiation oncologists and medical oncologists at the UCSF Helen Diller Family Comprehensive Cancer Center.

Application Deadline: Open Until Filled

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2. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Do you want to put your basic biochemistry and cell biology knowledge into action, and see your research translate into the clinic? The Chou Lab at the University of California, San Francisco is seeking to recruit an outstanding candidate to fill a Postdoctoral Fellow position. Research in the lab focuses on (1) understanding the molecular drivers of genitourinary malignancies, including prostate and bladder cancers; (2) investigating the mechanisms that contribute to disease progression, drug resistance and metastasis, including the role of the tumor immune microenvironment; and (3) developing novel therapies for genitourinary cancers. We are particularly interested in discovering novel surface protein targeting strategies and identifying new synthetic lethalities for specific molecular subtypes of cancer.

Application Deadline: Open Until Filled

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3. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are seeking a motivated postdoctoral researcher to work on a funded project at the UCSF Hypoxia Lab (hypoxialab.org) related to improving pulse oximeter performance in certain clinical scenarios including dark skin pigment and low perfusion states. Our lab has done seminal work to help identify limitations in current oximetry technology, and we are now embarking to solve these challenges. The Postdoctoral researcher will work closely with our multidisciplinary team to develop new validation protocols for use on human study subject testing, develop new in vitro testing devices to validate existing and new technologies, and collect data on performance of new and emerging clinical devices as part of the OpenOximetry.org project. This is a 1 year postdoctoral program, with possibility of extension for an additional year.

Application Deadline: Open Until Filled

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4. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Immuno-Oncology team is seeking to fill a post-doctoral position with a highly qualified, innovative, “outside of the box” thinking and collaborative candidate. The successful candidate will pursue research that seeks to dissect the anti-tumor T cell responses. The aim of the study is to generate new findings that will lead to developing innovative and effective targeted therapeutic strategies. The results of this research will be communicated by published outcomes in high-impact journals. Self-motivated and creative individuals with a track record in the field of immunology/tumor immunology and/or oncology, with relevant publications and a curiosity about translational opportunities should apply.

Application Deadline: Open Until Filled

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5. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Hansen lab is inviting highly qualified, inquisitive scientists to apply for positions as a Postdoctoral Researcher. The focus of our research is to understand how the basic cellular recycling process called autophagy is regulated during aging, using the nematode C. elegans and mammalian cell culture systems, and a combination of biochemical, imaging, and genetic approaches. Successful applicants for this career-development position will be involved in defining their own research direction.

Application Deadline: Open Until Filled

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6. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Drug Research Unit in the Department of Clinical Pharmacy, University of California at San Francisco is a clinical pharmacology research facility with the aim to provide state-of-the-art PK/PD studies to inform optimal doses and precise medicines for HIV, malaria, TB, and cancer. Major equipment includes two Sciex LC-MS/MS systems, two Waters UPLC-PDA systems, and an automated liquid handler for sample preparation. A postdoc research opportunity is available in the Drug Research Unit. The participant will conduct research on quantitative analysis of drugs including, but not limited to, antimalarials and antivirals using liquid chromatography-tandem mass spectrometry (LC-MS/MS) and other analytical methods.

A current project (funded by NIH, 1R21 AI153848-01A1) is to explore two-dimensional liquid chromatography tandem mass spectrometry method to quantify unbound antimalarial drugs in human plasma. The participant may also involve in pharmacokinetic data analysis including non-compartment analysis using WinNonlin® or modeling study using NONMEM®. Under the guidance of the mentor/Unit Co-directors, the participant will learn about quantitative analytical method development and validations and complex pharmacokinetic data analysis.

The fellow will also be encouraged to take advantage of other training and learning opportunities within the Department of Clinical Pharmacy, the School of Pharmacy, and other related entities at UCSF. The fellow will have opportunities to publish the work in professional journals and/or present data at professional meetings.

Application Deadline: Open Until Filled

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7. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A full-time postdoctoral scholar position is available for a highly motivated scientist interested in biostatistical and machine learning predictive modeling for healthcare and treatment-related outcomes and health economics research. The postdoctoral researcher will have the opportunity to lead statistical analyses working with large administrative and medical record datasets and will work with the UCSF Medication Outcomes Center (MOC) director Dr. Rodriguez-Monguio and her team to generate new statistical and modeling approaches to better understanding health outcomes in older patients with Alzheimer disease and related dementias.

The fellow will have opportunities to publish the work in professional journals and/or present data at professional meetings. The fellow will also be encouraged to take advantage of other training and learning opportunities within the Department of Clinical Pharmacy, the School of Pharmacy, and other related entities at UCSF. The initial appointment is 1 year with renewal for an additional 1 year by mutual agreement.

Application Deadline: Open Until Filled

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8. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral fellowship position for a highly motivated scientist is available in Drs.Chen/Bastian laboratory in the Helen Diller Family Cancer Center at the University of California, San Francisco. The project is focused on to study the signaling of mutant G proteins in uveal melanoma. Uveal melanoma is a rare cancer without any curative treatment options. It is genetically characterized by mutations in the Gαq signaling pathways, as our lab has previously reported (Nature: PMID: 19078957; N Engl J Med: PMID: 21083380; Oncogene: PMID: 24141786, Cancer Cell PMID: 28486107; Nature Genetics: PMID: 31253977; Oncogene: PMID: 33262460).

The candidate will help elucidate the downstream signaling, identify therapeutic targets, with the goal to identify effective therapeutic strategies, with the supports of grants from the National Cancer Institute, the Department of Defense and the Melanoma Research Alliance. The candidate will get in depth exposure to cutting edge in-vitro methods including multi-omic approaches and Crispr/Cas9 screens and use newly developed mouse models for in vivo studies.

Application Deadline: Open Until Filled

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9. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Winer lab at the Buck Institute studies how the immune system influences chronic inflammation during insulin resistance, which occurs in settings of metabolic syndrome and aging (see sample lab papers: Tsai et al Cell Metab 2018, 922-34; Ghazarian et al Science Immunol 2017, Apr 21; Winer et al Cell Metab 2016, 413-26; Luck et al Cell Metab 2015, 527-42; Winer et al Nature Med 2011, 610-7; Winer et al Nature Med 2009; 921-9). We also have an interest in mechanoimmunology (Du et Nat Rev Immunol 2023; Charkraborty et al Cell Rep 2021). We use immunology, molecular biology, including multi-omic assays, endocrinology, mouse models, and tissue culture assays to elucidate mechanisms by which immune cells and immune molecules influence inflammation in tissues.

Application Deadline: Open Until Filled

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10. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A full-time postdoctoral scholar position is available for a highly motivated scientist interested in clinical pharmacology research in HIV cure, HIV, COVID-19, long-COVID or Post Acute Sequalae of COVID-19 (PASC). As a member of a highly collaborative, cross disciplinary team of clinicians, virologists, immunologists, pharmacologists, pharmacists, epidemiologists, and statisticians, the postdoctoral researcher will have the opportunity to lead clinical studies and will work closely with the UCSF Drug Research Unit (DRU) co-Director Dr. Amelia Deitchman and her team.

Projects will generate new approaches in design and analysis of clinical trial data to inform drug development and dosing and underlying disease pathogenesis towards HIV cure and treatment of other viral, immune or inflammatory conditions. The postdoctoral scholar will have opportunities to publish the work in professional journals and/or present data at professional meetings. They will also be encouraged to take advantage of other training and learning opportunities within the Department of Clinical Pharmacy, the School of Pharmacy, and Center for AIDS Research at UCSF. The initial appointment is 1 year with renewal for an additional 1 year by mutual agreement.

Application Deadline: Open Until Filled

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11. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We have an exciting opportunity to join Pfizer’s Inflammation and Immunology Research Unit located in the heart of Cambridge’s biomedical research hub as a postdoctoral fellow. The position is with the Leukocyte Tissue Interface Group whose mission is to share immunology expertise across Pfizer’s various research units. The postdoctoral fellow will embark on a research project exploring novel engineering efforts to reprogram leukocytes using lipid-nanoparticle technologies, work collaboratively with diverse research teams within Pfizer, and publish their work in high-impact journals. This position presents a unique opportunity for well-trained immunologists and/or bioengineers who are also interested and passionate about receiving training in drug development.

Application Deadline: Open Until Filled

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12. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The PRISE Center was recently awarded a T32 grant from The National Heart, Lung, and Blood Institute (NHLBI). The goal of the Partnerships for Research in Implementation Science for Equity in Heart and Lung Diseases (PRISE-HL) T32 program is to provide support to outstanding post-doctoral scholars with interdisciplinary training in implementation science and health equity approaches to help transform the uptake and delivery of evidence-based interventions for heart and lung diseases in clinical and community settings.

Trainees will benefit from a team-based approach to mentoring through a career development committee that includes one faculty member with content expertise in clinical or translational research in heart and lung diseases, one faculty member with methodological expertise in implementation science-based methods, and one faculty member with expertise in health equity research (if not already covered).

Application Deadline: Open Until Filled

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13. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

HJF is seeking a Postdoctoral Fellow is Responsible for initiating and carrying out research projects in collaboration with a research team. Pursuits research along a focused line of inquiry and has a manuscript in development. This position will be in support of the Division of Infectious Diseases in the Department of Medicine at the Uniformed Services University (USU) of the Health Sciences in Bethesda, MD. The research seeks to contribute to improved treatment for the neglected tropical disease, cutaneous leishmaniasis, by developing novel oral and topical therapies in a mouse model, that could rapidly translate to human clinical trials.

Our projects focus on understanding the local and systemic adaptive immune responses to this intracellular parasite and resulting wound, to establish and test targeted therapies. Strong research interest and experience in immunology, molecular biology and animal handling are required for this position. Qualified candidates will have a doctorate in immunology, parasitology, microbiology or a closely-related field, preference for hands on experience with mouse models.

Application Deadline: Open Until Filled

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14. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Jennifer Doudna and Benjamin Rubin are recruiting a jointly supervised postdoc to work on in situ DNA editing of microbiomes at UC Berkeley. The candidate will join a highly collaborative team of researchers in the two labs, who are tightly integrated with the broader Innovative Genomics Institute’s Microbiome Editing Initiative. Projects will build on proof-of-principle community editing experiments to enact precise and efficient modification of microbiome members. This work relies on developing and using novel CRISPR-Cas editing systems, sequence-based tracking of edits, and next-generation tools for in situ control of edited organisms.

The postdoc will collaborate with a multidisciplinary group from UCSF, LBNL, JBEI, and Cedar-Sinai to apply microbiome editing to understand and control impactful microbial communities such as those in the human gut, cow rumen, and the rhizosphere. Specific projects range from identifying and modifying microbes with causal roles in inflammatory bowel disease and asthma, to mitigating methane emissions from livestock.

Application Deadline: Open Until Filled

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15. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The lab presents here an exciting opportunity to work with next generation technology that can record and stream intracranial cortical and basal ganglia physiology from patients with Parkinson’s disease. This will be combined with cutting edge computational and behavioral approaches plus experimental techniques and causal interventions including dopamine medications and closed-loop deep brain stimulation.

Application Deadline: Open Until Filled

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16. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The UCSF Little Lab is seeking a talented postdoctoral scholar to help understand the neurophysiology of motivation and dopamine in patients with Parkinson’s disease using intracranial brain recordings. This is an exciting opportunity to join an amazing international team (Masud Husain, Catherine Harmer, Matt Apps) supported through a Wellcome Trust Discovery award to uncover the fundamental circuitry of healthy motivation and apathy.

The lab presents here an exciting opportunity to work with next generation technology that can record and stream intracranial cortical and basal ganglia neurophysiology from people with Parkinson’s disease. This will be combined with cutting edge computational and behavioral approaches plus experimental techniques and causal interventions including dopamine modulation and closed-loop deep brain stimulation.

Application Deadline: Open Until Filled

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17. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our Neurocritical Care research group employs state-of-the-art statistical and machine learning approaches to decode information from massive databases of surface and invasive brain recordings (EEG & ECoG ) originating from the ICU. Our group is pursuing innovative and rigorous scientific research involving consciousness circuits in the brain, seizure and epilepsy prediction and modeling, as well as the effects of medications on brain rhythms and their impact on functional recovery after severe injury. We are integrating this unique type of physiological information about the brain with neuroimaging and electronic health records to provide a comprehensive picture of each patient and their care.

Application Deadline: Open Until Filled

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18. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A full-time postdoctoral scholar position is available for a highly motivated scientist interested in biostatistical analysis and discrete choice measurement for healthcare and treatment-related outcomes and health economics research. The postdoctoral researcher will have the opportunity to assist with all aspects of a newly funded Department of Defense 4 year project. They will work within the UCSF Program for Pharmacoeconomics and Policy Studies (PRoPEPS) led by Dr. Leslie Wilson and in conjunction with Hangar Clinics Nationally, as well as with other research projects in PRoPEPS, but with a large focus on statistical analysis.

Application Deadline: Open Until Filled

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The post 18 Postdoctoral Fellowships at University of California San Francisco, California, USA appeared first on FellowshipBard.

1. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoc research opportunity is available in the Drug Research Unit. The participant will conduct research on quantitative analysis of drugs including, but not limited to, antimalarials and antivirals using liquid chromatography-tandem mass spectrometry (LC-MS/MS) and other analytical methods. A current project (funded by NIH, 1R21 AI153848-01A1) is to explore two-dimensional liquid chromatography tandem mass spectrometry method to quantify unbound antimalarial drugs in human plasma.

Application Deadline: Open Until Filled

More Details

2. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A full-time postdoctoral scholar position is available for a highly motivated scientist interested in biostatistical and machine learning predictive modeling for healthcare and treatment-related outcomes and health economics research. The postdoctoral researcher will have the opportunity to lead statistical analyses working with large administrative and medical record datasets and will work with the UCSF Medication Outcomes Center (MOC) director Dr. Rodriguez-Monguio and her team to generate new statistical and modeling approaches to better understanding health outcomes in older patients with Alzheimer disease and related dementias.

Application Deadline: Open Until Filled

More Details

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3. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The laboratory of Christina Theodoris, MD, PhD, is seeking a highly motivated postdoctoral fellow with background in deep learning or network inference to join her research program in the Gladstone Institute of Cardiovascular Disease and Gladstone Institute of Data Science and Biotechnology. Our lab is focused on leveraging cutting-edge machine learning and experimental genomics to map the gene networks driving cardiovascular disease and develop network-correcting therapies.

Application Deadline: Open Until Filled

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4. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Graduate students and early-stage postdoctoral fellows interested in investigating pathophysiological mechanisms of synaptic and neural network dysfunctions in Alzheimer’s disease, epilepsy, and autism are encouraged to apply for a postdoctoral fellowship in the laboratory of Dr. Lennart Mucke at the Gladstone Institute of Neurological Disease. The successful candidate will join an interdisciplinary, highly interactive team of scientists who are committed to unraveling major brain disorders.

Application Deadline: Open Until Filled

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5. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The laboratory of Christina Theodoris, MD, PhD, is seeking a highly motivated postdoctoral fellow with background in experimental genomics and gene regulatory networks to join her research program in the Gladstone Institute of Cardiovascular Disease and Gladstone Institute of Data Science and Biotechnology. Our lab is focused on leveraging cutting-edge experimental genomics and machine learning to map the gene networks driving cardiovascular disease and develop network-correcting therapies.

Application Deadline: Open Until Filled

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6. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are seeking a highly motivated applicant for a full-time position as a Postdoctoral Fellow to join us in our efforts to systematically dissect multicellular interaction networks in human tumors with the goal to improve immunotherapy. We are a new lab within the joint Gladstone-UCSF Institute of Genomic Immunology. Our goal is to better understand how immune, stromal, and malignant cells are working together in complex human tissues to sense danger, initiate, execute, and terminate customized defense mechanisms, and re-establish homeostasis. We are especially interested in innate immune mechanisms that set the stage for whether or not anti-tumor responses are successful.

Application Deadline: Open Until Filled

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7. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Ramani Lab at the Gladstone Institute for Data Science & Biotechnology seeks to hire fully-funded postdoctoral fellows with interests in developing and applying novel methods to study gene regulation across the central dogma. The ideal candidate would have interest in one of several possible projects, including: 1) building on our recently published SAMOSA technique to address basic questions about cis regulatory element composition, trans-acting factor activities, and chromatin organization; 2) hybrid computational and molecular technology development projects linking the extended Myc network to mammalian development and cancer….

Application Deadline: Open Until Filled

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8. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Jain Lab at the Gladstone Institutes is looking for motivated, hard-working and curious applicants. We are particularly interested in recruiting a post-doc with experience and interest in mass-spectroscopy based methods (e.g. metabolomics, lipidomics). The ideal candidate will have an interest in driving metabolomics-focused projects – both independently and in collaboration with other lab members. They will help establish state-of-the-art metabolomics (with full-time access to a Thermo Q-Exactive or equivalent). The candidate will be interacting closely with the Gladstone Mass Spectroscopy Center.

Application Deadline: Open Until Filled

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9. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Jain Lab is looking for motivated, hard-working and curious applicants. We recently discovered that chronic hypoxia (equivalent to living in the mountains of Peru or Nepal) can serve as a therapy for mitochondrial disease in mouse models. This approach is currently in clinical trials. We are now interested in studying the effects of low and high oxygen on additional disorders and age-associated processes, as well as understanding the fundamentals of how organisms sense and adapt to varying oxygen tensions.

Application Deadline: Open Until Filled

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10. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral scholar position in the Huang Laboratory focuses on dissecting hippocampal circuits of learning and memory using in vivo electrophysiological approaches. In vivo network activity is used to measure and predict Alzheimer’s disease pathogenesis at the molecular, cellular, and behavioral level. Furthermore, in vivo network activity is used to develop and evaluate novel treatment strategies. This characterization is further assessed in comparison to in vitro electrophysiological phenotypes.

Application Deadline: Open Until Filled

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11. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The postdoctoral scholar will apply innovative epidemiological methods to support ongoing research studies on dementia, cognitive aging, and brain health. The candidate will have the opportunity to collaborate with CPBH investigators and participate in didactic sessions. Under the mentorship of Dr. Kristine Yaffe, the scholar will be responsible for driving original research projects while receiving epidemiological research training to become an independent investigator.

Application Deadline: Open Until Filled

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12. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are recruiting for one full time position, either a post-doctoral scholar or research scientist, who is interested in working on computational public health research related to infectious diseases. The project would focus on developing computational models to improve infectious disease surveillance, control strategies, and public health decision making. There are many ongoing projects related to COVID-19, hepatitis A, and neglected tropical diseases. The research group of Dr. Nathan Lo at UCSF uses computational modeling to inform and change public health policy in global infectious diseases. We mix fields of statistical modeling, simulation, epidemiology, and genomics to guide pressing policy issues.

Application Deadline: Open Until Filled

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13. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are seeking to hire highly motivated and independent post-doctoral scholars to join the EPPIcenter (Experimental & Population-based Pathogen Investigation Center) at the University of California, San Francisco, with Drs. Bryan Greenhouse and Isabel Rodríguez-Barraquer. The goal of our research center is to understand complex infectious disease dynamics by integrating state-of-the-art data collection, molecular technologies, and computational analysis. Our interdisciplinary approach provides novel insight into the targeting of interventions to reduce and ultimately eliminate infectious disease burden.

Application Deadline: Open Until Filled

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14. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Ideal candidates with have experience with modeling and/or genomic analysis and will study the transmission of malaria and apply genomic use cases using data from a large malaria genomic epidemiology project in southern Africa. Successful candidates will have the option to be based at one of the three institutions in alignment with research interests and benefit from a rich and interdisciplinary research environment, working closely with Drs. Bryan Greenhouse (UCSF), Amy Wesolowski (JHBSPH) and Robert Verity (Imperial) as well as a diverse and international team of collaborators.

Application Deadline: Open Until Filled

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15. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The EPPIcenter at UC San Francisco is seeking a talented scientist with a laboratory background to study the transmission and immunity of malaria using genomic and epidemiologic data. The successful candidate will be immersed in the multidisciplinary research environment of the Experimental and Population-based Pathogen Investigation center (EPPIcenter.ucsf.edu) and work closely with Drs. Bryan Greenhouse and Isabel Rodriguez-Barraquer along with a diverse team of scientists at UCSF and international collaborators.

Application Deadline: Open Until Filled

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16. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The newly-established AWARD Network (Advancing Workforce Analysis and Research for Dementia Network) will offer programs and activities to create a strong community of researchers engaged in research on the direct care workforce and its role in care for people living with dementia. The AWARD Network will develop infrastructure and relationships to generate research that supports evidence-based policy and practice to advance the capacity of the direct care workforce in serving people living with dementia.

Application Deadline: Open Until Filled

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17. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

D. E. Shaw Research is seeking Ph.D.–level scientists to join our New York–based team. This is a unique opportunity to develop and work with transformative technology in a dynamic, interdisciplinary environment. Candidates should have expertise in computational biophysics or chemistry, structural biology, or drug discovery. Relevant areas of experience might include direct application of molecular dynamics or machine learning to drug discovery, computer-aided drug design, molecular modeling, cheminformatics, fragment-based approaches, medicinal chemistry, biochemical and biophysical assay development, or target analysis and selection.

Application Deadline: Open Until Filled

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18. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A full-time postdoctoral scholar position is available for a highly motivated scientist interested in biostatistical and machine learning predictive modeling for healthcare and treatment-related outcomes and health economics research. The postdoctoral researcher will have the opportunity to lead statistical analyses working with large administrative and medical record datasets and will work with the UCSF Medication Outcomes Center (MOC) director Dr. Rodriguez-Monguio and her team to generate new statistical and modeling approaches to better understanding health outcomes in older patients with Alzheimer disease and related dementias.

Application Deadline: Open Until Filled

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19. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoc research opportunity is available in the Drug Research Unit. The participant will conduct research on quantitative analysis of drugs including, but not limited to, antimalarials and antivirals using liquid chromatography-tandem mass spectrometry (LC-MS/MS) and other analytical methods. A current project (funded by NIH, 1R21 AI153848-01A1) is to explore two-dimensional liquid chromatography tandem mass spectrometry method to quantify unbound antimalarial drugs in human plasma. The participant may also involve in pharmacokinetic data analysis including non-compartment analysis using WinNonlin® or modeling study using NONMEM®.

Application Deadline: Open Until Filled

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1. Postdoctoral Position in preclinical cancer research

Summary of Postdoctoral Fellowship:

A postdoctoral fellowship position for a highly motivated scientist is available in Drs. Bastian/Chen laboratory in the Helen Diller Family Cancer Center at the University of California, San Francisco. The project is focused on to study the signaling of mutant G proteins in uveal melanoma. Uveal melanoma is a rare cancer without any curative treatment options. It is genetically characterized by mutations in the Gαq signaling pathways, as our lab has previously reported (Nature: PMID: 19078957; N Engl J Med: PMID: 21083380; Oncogene: PMID: 24141786, Cancer Cell PMID: 28486107; Nature Genetics: PMID: 31253977; Oncogene: PMID: 33262460).

The candidate will help elucidate the downstream signaling, identify therapeutic targets, with the goal to identify effective therapeutic strategies, with the supports of grants from the National Cancer Institute, the Department of Defense and the Melanoma Research Alliance. The candidate will get in depth exposure to cutting edge in-vitro methods including multi-omic approaches and Crispr/Cas9 screens and use newly developed mouse models for in vivo studies.

Application Deadline: Open Until Filled

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2. Postdoctoral Position in COVID County Policies and Health

Summary of Postdoctoral Fellowship:

The Social Policies for Health Equity Research (SPHERE) program at UCSF seeks a postdoctoral fellow to conduct research on the effects of COVID-19 social and economic policies on health inequities. The COVID-19 pandemic prompted rapid and innovative policymaking around the world at the national, regional, and local levels. Researchers at SPHERE are creating a national database of local COVID-19-related public health and social policies.

The U.S. COVID-19 County Policy (UCCP) Database aims to provide a reliable record of what local governments have done in response to the pandemic. The postdoctoral fellow will link the policy database with national health data sets that provide individual-level information on mental health and healthcare utilization to assess how these pandemic-era policies affected these outcomes, particularly health inequities.

Application Deadline: Open Until Filled

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3. Postdoctoral Position in UCSF Drug Research

Summary of Postdoctoral Fellowship:

A postdoc research opportunity is available in the Drug Research Unit. The participant will conduct research on quantitative analysis of drugs including, but not limited to, antimalarials and antivirals using liquid chromatography-tandem mass spectrometry (LC-MS/MS) and other analytical methods. A current project (funded by NIH, 1R21 AI153848-01A1) is to explore two-dimensional liquid chromatography tandem mass spectrometry method to quantify unbound antimalarial drugs in human plasma. The participant may also involve in pharmacokinetic data analysis including non-compartment analysis using WinNonlin® or modeling study using NONMEM®.

Under the guidance of the mentor/Unit Co-directors, the participant will learn about quantitative analytical method development and validations and complex pharmacokinetic data analysis. The fellow will also be encouraged to take advantage of other training and learning opportunities within the Department of Clinical Pharmacy, the School of Pharmacy, and other related entities at UCSF. The fellow will have opportunities to publish the work in professional journals and/or present data at professional meetings.

Application Deadline: Open Until Filled

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4. Postdoctoral Position in Medicinal/ Analytical Chemistry

Summary of Postdoctoral Fellowship:

This research investigation will enable the selected scientist to leverage existing scientific knowledge and expertise while creating opportunities for innovation in new areas, especially to evaluate the chemical reactivity of drugs and drug products to form nitrosamines. Identification of methods to either remove the formed nitrosamines or more challengingly develop novel approaches to prevent the formation of nitrosamines will be a major focus area of this research. Note that the post-doctoral position is a hands-in laboratory-based position.

Application Deadline: Open Until Filled

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5. Postdoctoral Position in Epidemiology and Data Science of Adolescent

Summary of Postdoctoral Fellowship:

The Nagata Lab in the Division of Adolescent and Young Adult Medicine at the University of California, San Francisco is focused on using epidemiology and data science to determine downstream health effects of adolescent and young adult behaviors. Dr. Jason Nagata, MD, MSc, an Assistant Professor of Pediatrics, will be the supervisor for this position. The lab fosters interdisciplinary collaborations across medicine, psychology, social work, nutrition, epidemiology, biostatistics, and others. The lab environment also includes a wonderful team of students and trainees. More info about the lab and research topics can be found at the lab website: https://nagatalab.ucsf.edu/

Application Deadline: Open Until Filled

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6. Postdoctoral Position in Neurophysiology of Non motor symptoms in Parkinson’s using sensing enabled pacemakers

Summary of Postdoctoral Fellowship:

Dr Simon Little (https://littlelab.ucsf.edu/) is seeking a talented postdoctoral student to study the neurophysiology of motivation and non motor symptoms in Parkinson’s disease using sensing-enabled, deep brain stimulator pacemakers towards automated optimization of adaptive, personalized, brain stimulation. Dr Little and his lab (plus collaborators including Phil Starr) have pioneered adaptive deep brain stimulation and chronic neural sensing for movement disorders and are now working at the forefront of studies to develop personalized stimulation therapies for patients. This includes research to understand the link between cortico-basal network physiology and fundamental behavior, physiological biomarker discovery and testing of closed-loop stimulation strategies for neurological patients.

Application Deadline: Open Until Filled

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7. Staff Research Associate III Post Doctorate

Summary of Postdoctoral Fellowship:

The position involves research studies related to exosome research and cognitive function. Provides scientific knowledge and experience to the project, and initiates and performs specific research projects. Works independently in consultation with the Principal Investigator (PI).

Application Deadline: Open Until Filled

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8. Postdoctoral Position in Cardiac Diseases

Summary of Postdoctoral Fellowship:

We are seeking a driven and accomplished postdoctoral fellow with strong expertise in cardiovascular diseases to join ESB group in Cambridge, MA. The successful candidate will collaborate with colleagues within Pfizer to study targets of interest in related cardiac disorders, including heart failure, vascular dysfunction and rare cardiac disease at a fast pace.

Application Deadline: Open Until Filled

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9. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A full-time postdoctoral scholar position is available for a highly motivated scientist interested in biostatistical and machine learning predictive modeling for healthcare and treatment-related outcomes and health economics research. The postdoctoral researcher will have the opportunity to lead statistical analyses working with large administrative and medical record datasets and will work with the UCSF Medication Outcomes Center (MOC) director Dr. Rodriguez-Monguio and her team to generate new statistical and modeling approaches to better understanding health outcomes in older patients with Alzheimer disease and related dementias.

Application Deadline: Open Until Filled

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10. Postdoctoral Position in Lysosomal Biology

Summary of Postdoctoral Fellowship:

We are currently seeking to recruit a talented Postdoctoral Scientist to join our Pathway Biology group to explore mechanisms of lysosomal dysfunction linked to Parkinson’s disease (PD). Reporting to Anastasia Henry, the Postdoctoral Scientist will examine the molecular underpinnings of how variants in PD-linked proteins impact lysosomal function and lipid homeostasis and ultimately contribute to the pathogenesis of PD. The Postdoctoral Scientist will employ a cross-functional approach to work toward the ultimate goal of identifying novel potential targets for the treatment of PD.

Application Deadline: Open Until Filled

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11. Postdoctoral Position in Skin Cancer Genomics

Summary of Postdoctoral Fellowship:

The Shain laboratory is seeking to fill an open position for a postdoctoral scholar. For this position, the postdoctoral scholar will utilize multi-omic approaches to explore the biology of melanoma or cutaneous squamous cell carcinoma – several projects are available and can be discussed in more depth during the hiring process.

Application Deadline: Open Until Filled

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12. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Morrison lab in the Department of Radiology & Biomedical Imaging at UCSF is seeking to fill an open postdoctoral scholar position. In this position, the postdoctoral scholar will primarily contribute to R01-funded Parkinson’s disease research involving the use of multimodal MRI (fMRI, DTI, and QSM) to predict patient motor and cognitive outcomes with deep brain stimulation (DBS). There will also be opportunity to design and contribute to other DBS-related imaging projects such as developing novel surgical targeting strategies and/or elucidating underlying therapeutic DBS mechanisms.

Application Deadline: Open Until Filled

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13. Postdoctoral Position in Investigating Mechanisms of Dysregulated Immune Tolerance in Autoimmunity

Summary of Postdoctoral Fellowship:

The Ashouri Lab has an opening for a postdoctoral researcher who is interested in understanding how immune tolerance is broken in autoimmune diseases. Our lab is focused on advancing our knowledge of T cell signaling and repertoire thresholds required for immune tolerance. We study how the complex molecular interactions between cells alter immune health and the impact dysregulation in these communication pathways has on immune mediated diseases, such as rheumatoid arthritis. We utilize mouse models, human samples, along with molecular, cell-based, genetic, and multi-omic technologies including paired single-cell RNA and TCR-sequencing. A major driving force of the lab is to identify the TCR specificities, gene expression profile, and signaling networks of cells involved in antigen recognition in autoimmune diseases.

Application Deadline: Open Until Filled

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