1. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Research in Dr. Paust’s laboratory seeks to elucidate the molecular mechanisms underlying NK cell mediated adaptive immune responses in murine and human NK cells, and the development of novel anti-vial vaccines that target NK cell-mediated effector functions. Specifically, we seek to (i) understand NK cell responses and their contributions to host protection from acute and chronic viral infections, and in response to malignancy, (ii) develop and test novel vaccines and therapeutic approaches that elicit potent NK cell-mediated effector functions and immune memory, (iii) develop and evaluate NK cell-based immunotherapies to treat chronic viral infection or solid tumors, and (iv) to identify the molecular mechanism(s) of immunological memory in murine and human NK cells.

Application Deadline: Open Until Filled

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2. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are seeking an enthusiastic and self-motivated individual to join the Single Cell Biology (SCBL) Scientific Service team as an Associate Research Scientist. The ideal candidate will have a background in developing and establishing 3D cellular models and high content screening assays, liquid handling automation as well as expertise with single cell assays. This role requires strong expertise in 3D cell culture development, microscopy, image analysis, programming skills in Python, R or Matlab, data interpretation and excellent organizational skills and attention to detail. The Associate Research Scientist will work closely with the SCBL team to provide scientific services to the research community.

Application Deadline: Open Until Filled

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3. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The research projects will focus on NK cell responses to HIV using humanized mice and human specimens. The long-term goal of this project is to develop memory NK cell-based immunotherapies to prevent or cure HIV infection. This work will be performed using in humanized mice with a competent immune system and human specimens.

Application Deadline: Open Until Filled

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4. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Hinson lab is seeking an independent, highly motivated PhD-level scientist to join our trans-continental collaborative group funded by the Human Frontiers Science Program (HFSP). The overarching goal of this project is to leverage human pluripotent stem cell technology and advanced structural biology methods to define mechanisms and rules of sarcomere assembly and function. The ideal candidate would have a strong background in cell and molecular biology particularly in stem cell differentiation, advanced imaging and protein-protein interaction studies. As part of the group, this talented individual would have access to a world-class consortium of scientists across pluripotent stem cell biology, 3-dimensional organoids/microtissue assays, super resolution microscopy, and structural biology.

Application Deadline: Open Until Filled

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5. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral associate position is available in the laboratory of Dr. Jennifer Trowbridge at The Jackson Laboratory in Bar Harbor, Maine, to perform basic and translational research investigating the biological mechanisms that cause, and may be targeted to prevent, functional decline of blood and immune systems during aging. This work may include studies of aging hematopoietic stem cells as well as alterations in the bone marrow microenvironment with aging. The Trowbridge Lab offers a teamwork environment including collaborative opportunities with other leading laboratories in this field, nationally and internationally. Past and current trainees have been extremely successful in obtaining grant funding and fellowships.

Application Deadline: Open Until Filled

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6. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral associate position is available in the laboratory of Dr. Jennifer Trowbridge at The Jackson Laboratory in Bar Harbor, Maine, to perform basic and translational research investigating why and how blood cancers develop from pre-existing clonal hematopoiesis (CHIP/ARCH). The Trowbridge Lab offers a teamwork environment including collaborative opportunities with other leading laboratories nationally and internationally. Past and current trainees have been extremely successful in obtaining grant funding and fellowships.

Application Deadline: Open Until Filled

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7. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral associate position is available in the laboratory of Dr. Erik Bloss at The Jackson Laboratory in Bar Harbor, Maine, to perform basic research investigating the mechanisms by which exercise-responsive circuits may be manipulated to prevent structural and functional decline of cortical synapses during aging and in mouse models of Alzheimer’s disease. This work will include chemogenetic and optogenetic manipulations of neural activity in aging mice performing exercise and multiple cognitive assays as well as high resolution microscopic reconstruction of synapses on hypothalamic and cortical neurons.

Application Deadline: Open Until Filled

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8. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The O’Connell Lab at The Jackson Laboratory is seeking a Postdoctoral Associate in systems neuroscience of obesity and energy balance. We are interested in the role of gene – environment interactions in determining individual risk for obesity and related comorbidities, including age-related neurodegenerative diseases such as Alzheimer’s. The lab uses interdisciplinary approaches including Patch-seq for multimodal characterization of functional, morphological, and gene expression changes in single neurons. Projects may also employ in vivo Ca2+ imaging using fiber photometry, optogenetics, and chemogenetics in genetically diverse mouse models.

Application Deadline: Open Until Filled

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9. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Stitzel Lab at The Jackson Laboratory for Genomic Medicine in Farmington, CT is recruiting a Postdoctoral Associate to join our scientific team working to understand the precise genetic mechanisms controlling pancreatic islet identity and function and identify genes and response pathways that can be therapeutically targeted to prevent islet dysfunction and enhance islet resilience. We conduct innovative allelic and functional and single cell genomic analyses of primary human islets and employ high-throughput genomic techniques (e.g. CRISPR-based screens, MPRA) to (de)code the gene regulatory circuits controlling each islet cell type in human and mouse and uncover gene targets and molecular effects of human diabetes risk variants.

Application Deadline: Open Until Filled

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10. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The West lab is relocating to The Jackson Laboratory and is seeking an independent, highly motivated postdoctoral fellow to lead a collaborative research program to investigate how mitochondrial genome instability shapes immune responses in the melanoma tumor microenvironment. The overall goals of our laboratory are to delineate how mitochondria function as central regulators of innate immune and inflammatory responses and to investigate how mitochondria-immune crosstalk contributes to disease and aging. Our laboratory pursues a multidisciplinary approach by integrating cell biology, immunology, and physiology using cutting-edge techniques including engineered mouse models, single-cell multi-omics, super-resolution imaging, and CRISPR-based cellular tools.

Application Deadline: Open Until Filled

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11. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Stitzel Lab at The Jackson Laboratory for Genomic Medicine in Farmington, CT is recruiting a Postdoctoral Associate to join our scientific team working to identify new proteomic biomarkers of diabetes-associated stress responses in metabolic tissues (pancreas, adipose, liver, muscle). This individual will create and employ cell and mouse models to interrogate changes in protein localization, trafficking, and processing caused by insulin resistance or exposure to diabetogenic stressors using innovative proximity proteomic (e.g., BioID, TurboID) technology. Exceptional candidates can show early independence through the JAX Scholars Program.

Application Deadline: Open Until Filled

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12. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Jalili lab will open in July 2023 and is seeking a highly motivated and talented postdoctoral fellow to join our team. The successful candidate will have the opportunity to work on cutting-edge research projects related to studying the host immune-microbiome interface in the context of autoimmune skin diseases, infectious diseases, and aging, using state-of-the-art engineering tools. We implement different engineering technologies, particularly microneedle skin patches, to longitudinally monitor the cross-regulation of skin microbiome and immune system in the context of the inflammatory and autoimmune skin conditions.

Application Deadline: Open Until Filled

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13. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

NCI funded Postdoctoral position is available at The Jackson Laboratory (JAX) in Bar Harbor, Maine working under the direct supervision of Research Scientist Dr. Vishnu Hosur in the Shultz Lab to generate and validate humanized mouse models of cancer using novel gene-editing technologies. This position is ideally suited for an individual with a strong background in molecular biology (CRISPR/Cas) and next-generation sequencing methods. This position enables opportunities to learn basic skills in mammalian genetics. We seek motivated candidates, with Ph.D., MD, or DVM degree, who will be eager to take advantage of the unique opportunities available at JAX to advance their careers by combining existing molecular biology expertise with unparalleled mammalian genetics/genetic engineering training.

Application Deadline: Open Until Filled

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14. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Tarchini Lab at The Jackson Laboratory (http://tarchini-lab.org) is seeking a Postdoctoral Associate to complete a team currently composed of two postdocs, one research assistant and rotating students or shorter term trainees. The laboratory focuses on cell polarity mechanisms and their impact on the morphogenesis of sensory “hair” cells in the mouse auditory and vestibular organs, including hearing and balance ability. We are particularly interested in discovering new protein complexes organizing and elongating the stereocilia bundle, the apical hair cell compartment capturing sound or head movements. We are also interested in understanding how these proteins respond to damage, and more generally, to ask whether the molecular machinery assembling the stereocilia bundle during development could be leveraged to regenerate these structures after injury. We are independently funded with two R01 grants from NIH.

Application Deadline: Open Until Filled

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15. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Agoro lab at the Jackson Laboratory for Mammalian Genetics is seeking a highly motivated postdoctoral fellow to study redox molecular mechanisms that drive aging and chronic kidney disease. The overall goal of our laboratory is to understand the aging and kidney disease progression mechanisms using a systems biology approach as well as identifying new therapeutic strategies to improve renal function. Our laboratory is specialized in using a multidisciplinary approach that integrates genomics, proteomics, and metallomics. The postdoctoral scientist will lead an exciting project that applies a broad range of cutting-edge technologies, such as CRISPR-based tools, single-cell multi-omics, and kidney disease mouse models. The ideal candidate would have a strong background in molecular biology, mass spectrometry and genomic technologies.

Application Deadline: Open Until Filled

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16. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Tewhey Lab at The Jackson Laboratory in Bar Harbor, Maine is seeking a Postdoctoral Associate to join our team of scientists working to understand the precise genetic mechanisms underlying complex traits, and the impact human genetic variation has on gene regulatory function. Our group develops and applies novel high-throughput genetic techniques (e.g. MPRA and CRISPR based screens) to comprehensively characterize non-coding regions of the genome, in both mouse and human, to interpret the regulatory grammar of gene expression.

Application Deadline: Open Until Filled

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17. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral associate position is available in the laboratory of Dr. Elissa Chesler at The Jackson Laboratory in Bar Harbor, Maine to utilize systems genetics approaches to identify heritable effectors of behavior. The Chesler lab uses quantitative genetics, bioinformatics and behavioral science to understand and identify the biological basis for the relationships among behavioral traits with an emphasis on alcohol and substance use related traits. We develop and apply cross-species genomic data integration, advanced computing methods, and novel high-precision, high-diversity mouse populations to find genes associated with a constellation of behavioral disorders and other complex traits. In addition, Dr. Chesler leads the recently formed NIDA Research Center of Excellence P50 to bring together behavioral genetics experts from around the country to form the Center for Systems Neurogenetics of Addiction.

Application Deadline: Open Until Filled

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18. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are seeking a highly motivated and skilled postdoctoral researcher to join our research team in the field of human reproductive science and women’s health. The successful candidate will be working on an exciting project focused on studying endometriosis at the single cell resolution using spatial and single cell ‘omics, 3D cell culture assays and multiomic approaches.

Application Deadline: Open Until Filled

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19. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are looking for talented, intellectually curious postdoctoral candidates to embark on a unique postdoctoral training experience that leverages the rich domain expertise, mouse resources, and data services of JAX’s Center for the Addiction Biology, which includes the NIDA funded Center for Systems Neurogenetics of Addiction and other addiction research programs. As part of the Addiction Center team, the postdoctoral associate will contribute to innovative discoveries through application of their versatile technical expertise and domain knowledge. Engaging postdocs across disciplines and specific domain areas allows jointly mentored postdocs to expand their skill sets in emerging, interdisciplinary research areas.

Application Deadline: Open Until Filled

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The post 19 Postdoctoral Fellowships at Jackson Laboratory, California appeared first on FellowshipBard.

1. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral associate position is available in the laboratory of Dr. Erik Bloss at The Jackson Laboratory in Bar Harbor, Maine, to perform basic research investigating the mechanisms by which exercise-responsive circuits may be manipulated to prevent structural and functional decline of cortical synapses during aging and in mouse models of Alzheimer’s disease. This work will include chemogenetic and optogenetic manipulations of neural activity in aging mice performing exercise and multiple cognitive assays as well as high resolution microscopic reconstruction of synapses on hypothalamic and cortical neurons. The Bloss Lab offers a highly collaborative environment including opportunities with other leading laboratories in this field, nationally and internationally.

Application Deadline: Open Until Filled

More Details

2. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

NCI funded Postdoctoral position is available at The Jackson Laboratory (JAX) in Bar Harbor, Maine working under the direct supervision of Research Scientist Dr. Vishnu Hosur in the Shultz Lab to generate and validate humanized mouse models of cancer using novel gene-editing technologies. This position is ideally suited for an individual with a strong background in molecular biology (CRISPR/Cas) and next-generation sequencing methods. This position enables opportunities to learn basic skills in mammalian genetics. We seek motivated candidates, with Ph.D., MD, or DVM degree, who will be eager to take advantage of the unique opportunities available at JAX to advance their careers by combining existing molecular biology expertise with unparalleled mammalian genetics/genetic engineering training.

Application Deadline: Open Until Filled

More Details

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3. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The West lab is relocating to The Jackson Laboratory and is seeking an independent, highly motivated postdoctoral fellow to lead a collaborative research program to investigate how mitochondrial genome instability shapes immune responses in the melanoma tumor microenvironment. The overall goals of our laboratory are to delineate how mitochondria function as central regulators of innate immune and inflammatory responses and to investigate how mitochondria-immune crosstalk contributes to disease and aging. Our laboratory pursues a multidisciplinary approach by integrating cell biology, immunology, and physiology using cutting-edge techniques including engineered mouse models, single-cell multi-omics, super-resolution imaging, and CRISPR-based cellular tools.

Application Deadline: Open Until Filled

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4. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Technology Evaluation and Development laboratory seeks a Technology and Resource development PhD scientist to further the research and technology goals of the laboratory. The ideal candidate would have completed a PhD program and have 0-3 years of postdoctoral experience. They would be well-versed in research methods including DNA, RNA and protein quantitation and characterization and in working on multiple overlapping projects focused on the generation and characterization of novel pipelines to progress the capabilities of the laboratory in genome editing and the development of modified embryonic stem cells. Knowledge of mouse genetics would be an advantage but not required.

Application Deadline: Open Until Filled

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5. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Rosenthal and Korstanje Labs at the Jackson Laboratory (JAX) in Bar Harbor, Maine are seeking a Postdoctoral Associate to join their aging program focused on senescence. JAX is home to the Nathan Shock Center of Excellence in the Basic Biology of Aging, as well as the JAX Center for Aging Research, both led by Dr. Korstanje. Through the newly established JAX Cellular Senescence Network Mouse Tissue Mapping Center (JAX-Sen), led by Drs. Rosenthal and Korstanje, we are profiling senescent cells in kidney, placenta, pancreas, and heart, selected for their clinical relevance to chronic diseases of aging. These profiling activities will yield subcellular resolution of biomolecular content in senescent cells not possible with human samples, along with an expanded set of senescent cell biomarkers.

Application Deadline: Open Until Filled

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6. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Tarchini Lab at The Jackson Laboratory is seeking a Postdoctoral Associate to complete a team currently composed of two postdocs, one research assistant and rotating students or shorter term trainees. The laboratory focuses on cell polarity mechanisms and their impact on the morphogenesis of sensory “hair” cells in the mouse auditory and vestibular organs, including hearing and balance ability. We are particularly interested in discovering new protein complexes organizing and elongating the stereocilia bundle, the apical hair cell compartment capturing sound or head movements. We are also interested in understanding how these proteins respond to damage, and more generally, to ask whether the molecular machinery assembling the stereocilia bundle during development could be leveraged to regenerate these structures after injury. We are independently funded with two R01 grants from NIH.

Application Deadline: Open Until Filled

More Details

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7. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Tewhey Lab at The Jackson Laboratory in Bar Harbor, Maine is seeking a Postdoctoral Associate to join our team of scientists working to understand the precise genetic mechanisms underlying complex traits, and the impact human genetic variation has on gene regulatory function. Our group develops and applies novel high-throughput genetic techniques (e.g. MPRA and CRISPR based screens) to comprehensively characterize non-coding regions of the genome, in both mouse and human, to interpret the regulatory grammar of gene expression.

Application Deadline: Open Until Filled

More Details

8. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Hinson lab is seeking an independent, highly motivated PhD-level scientist (<2 years postdoc experience) to join our somatic cell genome-editing (SCGE) program funded by NIH U01 EB028898. The overarching goal of this project is to develop “one-and-done” genome editing therapeutics for inherited forms of heart failure, a condition with high morbidity and mortality. The ideal candidate would have a strong background in cell and molecular biology as well as next-generation sequencing methods and analyses. As part of the SCGE consortium, this talented individual would have access to a world-class consortium of experts in genome editing, delivery systems, and microphysiological human tissue and organoid models.

Application Deadline: Open Until Filled

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9. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We seek a computational biology postdoctoral associate to study transcriptome and epigenome heterogeneity in cancer initiation and aging. The Li Lab focuses on algorithm development and integrative mining from multi-omics data to determine how somatic mutations alter the blood cancer epigenome and gene regulation in the context of aging (Cancer Discovery, 2018; Science Advances, 2020; Cancer Discovery, 2020; Nature Communications, 2020). We also pioneered the rapidly growing field of transcriptomics and epigenomics (Nature Biotechnology, 2014; Genome Biology, 2014; Nature Medicine, 2016; Genome Biology, 2021). Currently, the Li Lab is funded by multiple NIH five-year grants from NCI and NIGMS, and is a core member of the NIA/NCI joint-funded OncoAging consortium. For additional information, visit the Li Lab online.

Application Deadline: Open Until Filled

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10. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Jackson Laboratory in Sacramento, CA has an excellent opportunity for an Autoimmune Scientist (autoimmune diseases/ immunology/ immune oncology) to join the In Vivo Innovation and Product Development team! Qualified candidates will possess a Ph.D. degree with 1-8 years working experience in autoimmune diseases, immunology and/or immuno-oncology research. Additional experience in in vivo pharmacology, flow cytometry, cell culture experience is also highly desired. The individual will work hands on at the research bench with oncology mouse models for drugs efficacy and safety studies;FACS; murine models for autoimmune diseases, oncology and/or immuno-oncology and inflammatory diseases models.

Application Deadline: Open Until Filled

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11. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Postdoctoral Positions in Three-dimensional (3D) Chromatin Genomics. Chromatin interactions and its 3D structure play a major role in regulating gene expression by bringing together regulatory elements that are distal on the linear genome in close physical proximity with each other. Our Lab have pioneered genomic technologies for genome-wide profiling chromatin interactions. We are seeking enthusiastic, highly skilled computational and experimental post-docs to generate and analyze human chromatin interaction datasets in integration with other genomics and genetics datasets.‬ ‬‬‬‬‬‬‬‬‬

Application Deadline: Open Until Filled

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12. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Jalili lab will open in July 2023 and is seeking a highly motivated and talented postdoctoral fellow to join our team. The successful candidate will have the opportunity to work on cutting-edge research projects related to establishing an in vitro host immune-microbiome culture model for disease modeling, and vaccine and therapeutic development. We implement multiple technologies, like organoid engineering, organ on a chip platforms, microfluidics and microbiology for modeling skin and intestine inflammatory, autoimmune and cancer conditions, such as dermatitis, psoriasis, inflammatory bowel disease (IBD), Crohn’s disease (CD), ulcerative colitis (UC), and colon cancer. We will have access to both animal- and patient-derived cells/organoids and microbiome and we will use our complex Organ Chip models to study the underlying mechanisms of these diseases and the role of immune cells in regulating the dysbiosis in skin and intestinal microbial composition.

Application Deadline: Open Until Filled

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13. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Jalili lab will open in July 2023 and is seeking a highly motivated and talented postdoctoral fellow to join our team. The successful candidate will have the opportunity to work on cutting-edge research projects related to studying the host immune-microbiome interface in the context of autoimmune skin diseases, infectious diseases, and aging, using state-of-the-art engineering tools. We implement different engineering technologies, particularly microneedle skin patches, to longitudinally monitor the cross-regulation of skin microbiome and immune system in the context of the inflammatory and autoimmune skin conditions.

Application Deadline: Open Until Filled

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The post 13 Postdoctoral Fellowships at Jackson Laboratory, California, USA appeared first on FellowshipBard.

1. Postdoctoral Position in Autoimmune / Oncology

Summary of Postdoctoral Fellowship:

The Jackson Laboratory in Sacramento, CA has an excellent opportunity for an Autoimmune Scientist (autoimmune diseases/ immunology/ immune oncology) to join the In Vivo Innovation and Product Development team! Qualified candidates will possess a Ph.D. degree with 1-8 years working experience in autoimmune diseases, immunology and/or immuno-oncology research. Additional experience in in vivo pharmacology, flow cytometry, cell culture experience is also highly desired. The individual will work hands on at the research bench with oncology mouse models for drugs efficacy and safety studies;FACS; murine models for autoimmune diseases, oncology and/or immuno-oncology and inflammatory diseases models.

Application Deadline: Open Until Filled

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2. Postdoctoral Position in genetics

Summary of Postdoctoral Fellowship:

The Tewhey Lab at The Jackson Laboratory in Bar Harbor, Maine is seeking a Postdoctoral Associate to join our team of scientists working to understand the precise genetic mechanisms underlying complex traits, and the impact human genetic variation has on gene regulatory function. Our group develops and applies novel high-throughput genetic techniques (e.g. MPRA and CRISPR based screens) to comprehensively characterize non-coding regions of the genome, in both mouse and human, to interpret the regulatory grammar of gene expression.

Application Deadline: Open Until Filled

More Details

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3. Postdoctoral Position in Hearing and Balance

Summary of Postdoctoral Fellowship:

The Tarchini Lab at The Jackson Laboratory is seeking a Postdoctoral Associate to complete a team currently composed of two postdocs, one research assistant and rotating students or shorter term trainees. The laboratory focuses on cell polarity mechanisms and their impact on the morphogenesis of sensory “hair” cells in the mouse auditory and vestibular organs, including hearing and balance ability. We are particularly interested in discovering new protein complexes organizing and elongating the stereocilia bundle, the apical hair cell compartment capturing sound or head movements.

Application Deadline: Open Until Filled

More Details

4. Postdoctoral Position in genetic variation

Summary of Postdoctoral Fellowship:

The Baker lab at The Jackson Laboratory is seeking an independent, highly motivated PhD-level scientist to lead a collaborative research program investigating the impact of genetic variation on differentiation propensity using cellular systems genetics. The Baker lab studies how genetic variation impacts phenotypic variation through changes in the epigenome using a combination of approaches including in vitro cellular models, (epi)genomics assays, and genome editing. The Baker lab is looking for applicants who come from an experimental background looking to apply functional genomic approaches towards understanding systems-level regulation.

Application Deadline: Open Until Filled

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5. Postdoctoral Position in Aging 

Summary of Postdoctoral Fellowship:

The Rosenthal and Korstanje Labs at the Jackson Laboratory (JAX) in Bar Harbor, Maine are seeking a Postdoctoral Associate to join their aging program focused on senescence. JAX is home to the Nathan Shock Center of Excellence in the Basic Biology of Aging, as well as the JAX Center for Aging Research, both led by Dr. Korstanje. Through the newly established JAX Cellular Senescence Network Mouse Tissue Mapping Center (JAX-Sen), led by Drs. Rosenthal and Korstanje, we are profiling senescent cells in kidney, placenta, pancreas, and heart, selected for their clinical relevance to chronic diseases of aging.

Application Deadline: Open Until Filled

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6. Postdoctoral Position in Single Cell Biology

Summary of Postdoctoral Fellowship:

The Single Cell Biology laboratory is a research-driven core service within The Jackson Laboratory, providing state-of-the-art single cell and spatial assays to the research community and its stakeholders. The workforce in the Single Cell Biology laboratory comprises a leadership team (Director and Associate Director), Ph.D. level staff scientists, cellular biologists and specialists, and computational analysts. We are looking for an Associate Research Scientist (Ph.D. level staff scientist), whose primary responsibilities concern cellular and molecular biology laboratory techniques.

Application Deadline: Open Until Filled

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7. Postdoctoral Position in Addiction Biology

Summary of Postdoctoral Fellowship:

We are looking for talented, intellectually curious postdoctoral candidates to embark on a unique postdoctoral training experience that leverages the rich domain expertise, mouse resources, and data services of JAX’s Center for the Addiction Biology, which includes the NIDA funded Center for Systems Neurogenetics of Addiction and other addiction research programs. As part of the Addiction Center team, the postdoctoral associate will contribute to innovative discoveries through application of their versatile technical expertise and domain knowledge.

Application Deadline: Open Until Filled

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8. Postdoctoral Position in Chromatin Genomics

Summary of Postdoctoral Fellowship:

The 3D Chromatin Genomics Lab at JAX-GM is seeking to appoint a postdoctoral associate to participate in research directed toward elucidating the structures and dynamics of complex genomes. Postdoctoral Positions in Three-dimensional (3D) Chromatin Genomics ‪‪Chromatin interactions and its 3D structure play a major role in regulating gene expression by bringing together regulatory elements that are distal on the linear genome in close physical proximity with each other. Our Lab have pioneered genomic technologies for genome-wide profiling chromatin interactions.

Application Deadline: Open Until Filled

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9. Postdoctoral Position in Genomic Technologies

Summary of Postdoctoral Fellowship:

Perform experiments and obtain data with minimal guidance; supervise staff to do the same. Initiate scientific projects to develop and/or validate new protocols relevant to JAX’s research mission Work closely with JAX faculty to integrate such technologies into multiple research programs Publish in peer review journals; contribute to scientific research papers, grant applications and reports. Efficient, flexible and self-motivated work ethic; to be utilized in planning, executing, and analyzing independent research projects.

Application Deadline: Open Until Filled

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10. Postdoctoral Position in Molecular Biology

Summary of Postdoctoral Fellowship:

The Hinson lab is seeking an independent, highly motivated PhD-level scientist (<2 years postdoc experience) to join our somatic cell genome-editing (SCGE) program funded by NIH U01 EB028898. The overarching goal of this project is to develop “one-and-done” genome editing therapeutics for inherited forms of heart failure, a condition with high morbidity and mortality. The ideal candidate would have a strong background in cell and molecular biology as well as next-generation sequencing methods and analyses.

Application Deadline: Open Until Filled

More Details

11. Postdoctoral Position in Clonal Hematopoiesis and Leukemia

Summary of Postdoctoral Fellowship:

A postdoctoral associate position is available in the laboratory of Dr. Jennifer Trowbridge at The Jackson Laboratory in Bar Harbor, Maine, to perform basic and translational research investigating why and how blood cancers develop from pre-existing clonal hematopoiesis (CHIP/ARCH). The Trowbridge Lab offers a teamwork environment including collaborative opportunities with other leading laboratories nationally and internationally. Past and current trainees have been extremely successful in obtaining grant funding and fellowships.

Application Deadline: Open Until Filled

More Details

12. Postdoctoral Position in Biology of Aging Hematopoiesis

Summary of Postdoctoral Fellowship:

A postdoctoral associate position is available in the laboratory of Dr. Jennifer Trowbridge at The Jackson Laboratory in Bar Harbor, Maine, to perform basic and translational research investigating the biological mechanisms that cause, and may be targeted to prevent, functional decline of blood and immune systems during aging. This work may include studies of aging hematopoietic stem cells as well as alterations in the bone marrow microenvironment with aging. The Trowbridge Lab offers a teamwork environment including collaborative opportunities with other leading laboratories in this field, nationally and internationally.

Application Deadline: Open Until Filled

More Details

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13. Postdoctoral Position in Molecular Biology 

Summary of Postdoctoral Fellowship:

The Hinson lab is seeking an independent, highly motivated PhD-level scientist (<2 years postdoc experience) to join our somatic cell genome-editing (SCGE) program funded by NIH U01 EB028898. The overarching goal of this project is to develop “one-and-done” genome editing therapeutics for inherited forms of heart failure, a condition with high morbidity and mortality. The ideal candidate would have a strong background in cell and molecular biology as well as next-generation sequencing methods and analyses.

Application Deadline: Open Until Filled

More Details

14. Postdoctoral Position in Computational Cancer Biology

Summary of Postdoctoral Fellowship:

We seek a computational biology postdoctoral associate to study transcriptome and epigenome heterogeneity in cancer initiation and aging. The Li Lab focuses on algorithm development and integrative mining from multi-omics data to determine how somatic mutations alter the blood cancer epigenome and gene regulation in the context of aging (Cancer Discovery, 2018; Science Advances, 2020; Cancer Discovery, 2020; Nature Communications, 2020).

Application Deadline: Open Until Filled

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15. Postdoctoral Position in Computational  Biology

Summary of Postdoctoral Fellowship:

The Carter Lab has an opening for two postdoctoral associates in the computational biology of Alzheimer’s disease. These positions will be part of our ongoing studies that seek to understand the origins, progression, and potential treatments of Alzheimer’s disease through multiple experimental platforms.

We are seeking postdoctoral associates to answer two main computational questions: How can we combine multi-omics, biomarker, and bioimaging data across multiple species to model the origins, progression, and therapeutic interventions for Alzheimer’s disease? How can we implement rigorous preclinical testing of precision therapeutics that target Alzheimer’s disease pathways in advanced mouse models?

Application Deadline: Open Until Filled

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16. Postdoctoral Position in genetics

Summary of Postdoctoral Fellowship:

A postdoctoral associate position is available in the laboratory of Dr. Elissa Chesler at The Jackson Laboratory in Bar Harbor, Maine to utilize systems genetics approaches to identify heritable effectors of behavior. The Chesler lab uses quantitative genetics, bioinformatics and behavioral science to understand and identify the biological basis for the relationships among behavioral traits with an emphasis on alcohol and substance use related traits.

Application Deadline: Open Until Filled

More Details

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The post 16 Postdoctoral Fellowships at Jackson Laboratory, Maine appeared first on FellowshipBard.

1. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Ucar lab is seeking motivated computational scientists interested in studying how epigenomes of human immune cells change with age and diseases including COVID-19. We use diverse approaches in genomics, bioinformatics, systems biology and immunology to understand how epigenetic regulation of gene expression programs are disrupted by genetics and environment. We are seeking highly-motivated individuals who have prior experience with programming and genomic data analyses.

Application Deadline: Open Until Filled

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2. Clinical Research Project Manager

Summary of Postdoctoral Fellowship:

Overall project management and coordination: Facilitate cross-group communications during project execution regarding project scope, goals and deliverables, execution and completion. This includes monitoring progress on expected deliverables and assigned tasks. Organize IRB work across different sub-awardees and JAX. Maintain lists of priorities, schedules, action items, accountability, and deliverables in defined areas of research projects. This includes providing project tracking and updates on a consistent basis to the JAX team.

Champion planning and execution of all research meetings and all relevant documentation. This includes creation and distribution of formal, accurate, and tailored project summaries, according to project delivery timetables. Demonstrate commitment to creating a positive work environment and high-performance culture, which includes continued effort toward improving process and workflow, coping with and supporting change and commitment to a solution driven approach to problem.

Application Deadline: Open Until Filled

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3. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are seeking postdoctoral researchers to develop computational and genomic approaches for understanding 3D genome biology under the light of diverse genomic and genetic information. We are seeking self-motivated, independent individuals who are interested in building their own career paths; however, postdoctoral fellows are expected to coordinate with and report to the PI responsible for the research area(s) addressed by their project.

Application Deadline: Open Until Filled

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4. Postdoctoral Position in Molecular Genetics

Summary of Postdoctoral Fellowship:

NCI funded Postdoctoral position is available at The Jackson Laboratory (JAX) in Bar Harbor, Maine working under the direct supervision of Research Scientist Dr. Vishnu Hosur in the Shultz Lab to generate and validate humanized mouse models of cancer using novel gene-editing technologies. This position is ideally suited for an individual with a strong background in molecular biology (CRISPR/Cas) and next-generation sequencing methods.

This position enables opportunities to learn basic skills in mammalian genetics. We seek motivated candidates, with Ph.D., MD, or DVM degree, who will be eager to take advantage of the unique opportunities available at JAX to advance their careers by combining existing molecular biology expertise with unparalleled mammalian genetics/genetic engineering training.

Application Deadline: Open Until Filled

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5. Neurobehavioral Scientist

Summary of Postdoctoral Fellowship:

We are recruiting a skilled and enthusiastic Neurobehavioral Scientist to join our Neurobehavioral Phenotyping (NBP) Core with the CBA. Our activities focus on neurodevelopmental and neurodegenerative diseases, substance use and other psychiatric disorders, neuromuscular disorders, and aging. This PhD level scientist will deliver outstanding study design and execution, data analysis and interpretation, protocol development and improvement, and training of The Jackson Laboratory (JAX) faculty and staff in complex and diverse neurobehavioral phenotyping paradigms.

Application Deadline: Open Until Filled

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6. Postdoctoral Position in Tumor Microenvironment and Tumor Immunology

Summary of Postdoctoral Fellowship:

A postdoctoral associate position is available in the lab of Dr. Gary Ren to study tumor microenvironment and tumor immunology in cancer therapy resistance and metastatic relapse. Using genomic and proteomic approaches, cancer patient specimen analysis and mouse models of diverse cancer types, Dr. Ren’s lab mainly focuses on elucidating how mesenchymal lineage cells and immunoregulatory myeloid cells modulate the adaptive immune responses in treatment resistance and metastatic relapse.

These studies will fully take advantage of the unique research platform at JAX–patient-derived xenograft (PDX) tumors in humanized mouse models, with the research goal to develop novel strategies targeting tumor microenvironment to improve the efficacies of conventional cancer therapies and new therapeutics such as immunotherapy.

Application Deadline: Open Until Filled

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7. Associate Research Scientist

Summary of Postdoctoral Fellowship:

Scientific service-associated Research Scientists provide leadership for technical development, act as senior support to faculty-based science, and contribute as the institutional memory for complex technologies important to the Laboratory.

Application Deadline: Open Until Filled

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8. Research Scientist in Genomic Technologies

Summary of Postdoctoral Fellowship:

Perform experiments and obtain data with minimal guidance; supervise staff to do the same. Initiate scientific projects to develop and/or validate new protocols relevant to JAX’s research mission Work closely with JAX faculty to integrate such technologies into multiple research programs Publish in peer review journals; contribute to scientific research papers, grant applications and reports. Efficient, flexible and self-motivated work ethic; to be utilized in planning, executing, and analyzing independent research projects.

Application Deadline: Open Until Filled

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9. Postdoctoral Position in Neuroscience

Summary of Postdoctoral Fellowship:

The focus of the lab is to determine how brain circuits reorganize after a stroke, contributions of these reorganizational process to motor function, molecular signatures that drive recovery and therapeutic targets for stroke. We use a host of techniques including but not limited to large-scale mesoscopic calcium imaging, optogenetics, gene targeting with viral vectors or transgenics, transcriptomics and ethological measurements of behavior.

Application Deadline: Open Until Filled

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10. Associate Research Scientist

Summary of Postdoctoral Fellowship:

The Trowbridge lab at The Jackson Laboratory is seeking an independent, highly motivated PhD-level scientist to lead a collaborative research program investigating the biological basis of hematopoietic stem cell aging and how this modifies risk of aging-associated diseases including cancer, cardiovascular disease, and Alzheimer’s disease. The Trowbridge lab studies hematopoietic stem cell aging, clonal hematopoiesis, and blood cancer development using a combination of approaches including engineered mouse models, in vivo and in vitro cellular assays, (epi)genomics assays, and cellular imaging.

Application Deadline: Open Until Filled

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