1. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow position is available in Dr. Rupangi Vasavada’s lab in the Department of Translational Research and Cellular Therapeutics in the Arthur Riggs-Diabetes and Metabolism Research Institute at City of Hope. The lab is interested in understanding the pathophysiology of diabetes, assessing the role of extracellular vesicles in Type 1 and Type 2 diabetes as well as in aging. We are targeting specific biological pathways to enhance beta cell health, testing their effects from bench to bedside, to find therapeutics to combat the disease. The lab employs a combination of cellular and molecular techniques, mouse models and patient samples to assess these areas.

Application Deadline: Open Until Filled

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2. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. Behnam Badie at the Beckman Research Institute of City of Hope, a prestigious NCI-designated Comprehensive Cancer Center. The research interests of Behnam Badie, M.D., focus on brain tumor immunology. More specifically, his research team is attempting to develop novel immunotherapy approaches for malignant brain tumors through the activation of microglia and macrophages using nanoparticles. This research is currently funded by the National Cancer Institute and other organizations.

Application Deadline: Open Until Filled

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3. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. David Chen’s research group at the Beckman Research Institute of City of Hope is seeking a highly skilled and motivated Postdoctoral Fellow to join their dynamic team. Dr. Chen is a distinguished leader serving as the Director of the Division of Epigenetics and Transcriptional Engineering at City of Hope Cancer Center. The primary focus of his lab revolves around investigating epigenetic mechanisms, drug resistance, and identifying therapeutic targets in various cancers through cutting-edge techniques such as high throughput genetic screens. The lab is proficient in high-throughput CRISPR genetic screens for identifying novel therapeutic targets for cancer treatment.

Application Deadline: Open Until Filled

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4. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow to study the molecular mechanisms involved in the increased risk of cancer in patients with diabetes. The Shuck lab specializes in detailed studies of the cellular impact of reactive molecules produced during metabolic dysfunction. Specifically, we are interested in investigating the induction of covalent adducts on DNA, RNA, and protein using human prostate cancer cell lines. The position will encompass a variety of techniques including sterile cell culture, characterization of cellular changes induced by hyperglycemia, use of biochemical assays, and analytical techniques such as HPLC and mass spectrometry. The trainee will benefit from a close interaction with world-class clinical and basic science faculty and staff, and gain experience in state-of-the-art genomics and analytical techniques.

Application Deadline: Open Until Filled

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5. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr Ed Boas, at the Beckman Research Institute of City of Hope, a prestigious NCI-designated Comprehensive Cancer Center. We are looking for a biomedical engineer, materials scientist, immunologist, or cancer biologist who can help us develop new minimally invasive cancer therapies, such as new materials or devices for drug delivery into tumors (percutaneous or intra-arterial). We are one of the few interventional oncology groups in the United States with a basic science lab, large animal tumor model, and several active clinical trials, which enables us to translate new discoveries from bench to animal to bedside.

Application Deadline: Open Until Filled

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6. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Shi laboratory has been well known for stem cell research, including stem cell-based disease modeling and cell therapy development. This laboratory is one of the pioneers in establishing disease models and cell therapies using the human induced pluripotent stem cell (iPSC) platform and has published extensively in this area. Some of the papers published by the Shi laboratories include Shi et al. Nature Reviews Drug Discovery 16: 115-130, 2017; Li et al. Cell Stem Cell 23: 239-251, 2018; Feng et al. Advanced Science 7: 2002155, 2020; Wang, et al. Cell Stem Cell 28: 331-342.e5, 2021; Chen et al. Advanced Science: 8: e2101462, 2021; Cui et al. Nature Cancer 2: 932-949, 2021.

Application Deadline: Open Until Filled

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7. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. ZJ Sun at Beckman Research Institute of City of Hope, one of a prestigious group of NCI-designated Comprehensive Cancer Centers. The candidate will directly work on the novel and ongoing projects on prostatic stem cells and stem cell niches in prostate development and tumorigenesis using “cutting edge” and unbiased analytic tools and unique and innovative genetically engineered mouse models (please see some of the recent publications: PLoS Genet 2020 Jan 13:16(1):e1008588; Development 2021 Jan 11:148(1):dev196048; Development 2021 Oct 1:148(19):dev199738; Nat Commun 2022 Jul 28:13:4364; Nat Commun 2022 Nov 2:13:6552).

Application Deadline: Open Until Filled

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8. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. Yuman Fong, at the Beckman Research Institute of City of Hope, a prestigious NCI-designated Comprehensive Cancer Center. The candidate will directly work on oncolytic virus project, which involves assessing safety and anti-tumor efficacy of different viral constructs, in vitro and in mice. Oncolytic virotherapy is a major focus of our laboratory. The candidate will be working with our oncolytic poxvirus (CF33) and potentially other viral platforms.

Application Deadline: Open Until Filled

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9. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. Alberto Pugliese, MD in the AR-DMRI Department of Diabetes Immunology. The research is highly translational and primarily focused on human type 1 diabetes. The candidate will participate in several projects. Major ongoing projects are investigating miRNA biomarkers, pancreas pathology, and novel therapeutics, also in the context of the analysis of live pancreas tissue from organ donors obtained from the Network for Organ Donors with Diabetes (nPOD), of which Dr. Pugliese is Executive Co-Director, and in future clinical trials. Upcoming studies are projected to include the analysis of samples from patients with type 1 diabetes participating in clinical trials, with trials expected to start in late 2023 and 2024. Additional studies involve analysis of samples from recipients of pancreas-kidney transplant in the context of recurrent type 1 diabetes.

Application Deadline: Open Until Filled

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10. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The laboratory of Binghui Shen, Ph.D. at The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. The Shen laboratory has been focusing on DNA replication/repair pathway components, cancer genetics and epigenetics, and cancer etiological and therapeutics modeling. The laboratory is seeking additional members to work on several new projects. Recent Ph.D. graduates or equivalents in the field of biological/medical sciences with ambition for a scientific career and interest in DNA replication and repair, genome stability, and cancer biology and skills in molecular biology, genetics or biochemistry are encouraged to apply. Bioinformatics and data mining skills are a plus for considerations.

Application Deadline: Open Until Filled

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11. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our research is focused on translational research as it relates to genomic and epigenomic characterization of various gastrointestinal cancers (GI) including colorectal, pancreatic and gastric cancers, and some of the key research topics include: 1) Development of circulating DNA/RNA-based liquid biopsy biomarkers for cancer diagnosis, prognosis and predictive response to various therapies. 2) Study the epigenetic basis of GI cancers (e.g. aberrant DNA methylation, histone modifications and non-coding RNAs. 3) The genetic basis of early-onset and familial/hereditary colorectal cancers. 4) The role of tumor microenvironment, stem cells, immune regulation and identification of novel targeted therapies. 5) The role of extracellular vesicles/exosomes as in cancer pathogenesis and their role as disease biomarkers.

Application Deadline: Open Until Filled

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12. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Join our successful and productive research team at the Beckman Research Institute at City of Hope where we are studying the biological mechanisms of breast cancer susceptibility in the context of aging. This current position is focused on using cell and molecular techniques to examine emergent mechanical properties of epithelial cells that are highly susceptible to breast cancer initiation. This mechanobiology work is the product of a long-term, NIH funded, collaboration with a bioengineering group at UC Berkeley. We are using, and evolving, a mechano-node pore sensing (mechano-NPS) platform to explore unique mechanical properties of cells that are associated with chronological or biological age, lineage, and cancer progression stage.

Application Deadline: Open Until Filled

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13. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow position is available in the laboratory of Edwin R. Manuel, PhD, at City of Hope, Beckman Research Center, Monrovia, CA. Our lab is interested in utilizing tumor-colonizing, bacterial-based agents as novel immunotherapy for solid and hematologic malignancies. We are recruiting enthusiastic, motivated scientists who are seeking a fast-paced academic research environment. Our lab in the Department of Immuno-Oncology focuses on engineering tumor-colonizing bacteria to target components of the tumor microenvironment that contribute poor drug delivery, immune suppression and cancer metabolism.

Application Deadline: Open Until Filled

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14. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow for translational research in the field of cancer biology and therapy. Ongoing studies are focusing on targeting ovarian cancer tumor microenvironment by conditionally replicative oncolytic virus and development of new agents targeting extrinsic and intrinsic apoptotic pathways.

Application Deadline: Open Until Filled

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15. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow position is available in the laboratory of Dr. Heather McGee, MD, PhD, Assistant Professor in the Departments of Radiation Oncology and Immuno-Oncology in the Beckman Research Institute at City of Hope. Dr. McGee is looking for a post-doctoral fellow who is very motivated to lead exciting scientific projects and test novel hypotheses. The post-doctoral researcher must have a background in tumor immunology, murine tumor models and multicolor flow cytometry. The goals of the McGee lab are to understand how radiation activates tissue resident immune cells in various tumor microenvironments. The long-term goals of the McGee lab are to identify key molecular and immunologic pathways activated by radiation that can be targeted to enhance anti-tumor immunity and/or minimize normal tissue toxicity for gastrointestinal malignancies.

Application Deadline: Open Until Filled

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16. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are recruiting enthusiastic, motivated scientists who are seeking a fast-paced, team-based academic research environment. Our lab in the Department of Immuno-oncology focuses on how blood and immune cells develop, function, and interact with other cells, with a second focus on how blood stem cells become malignant. We use mass spectrometry to identify activated protein circuits in rare blood stem and progenitor cell populations, including therapeutic chimeric antigen receptor (CAR) T cells, and combine that knowledge with fundamental immunological principles to improve and devise new therapies for pediatric cancers and blood disorders.

Application Deadline: Open Until Filled

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17. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. The Williams Research Team seeks a self-motivated, results-driven postdoc to drive the development of the generation of therapeutic monoclonal antibodies. Expertise required include thorough knowledge of protein engineering (cloning, expression, purification), crystallography (crystallization, optimization, data collection and structure determination), biochemistry (enzyme kinetics) and biophysics (Surface Plasmon Resonance, Iosthermal Ttitration Calorimetry, etc).

Application Deadline: Open Until Filled

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18. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are seeking a talented and motivated Postdoctoral Fellow to work in the laboratory of Dr. Srividya Swaminathan in the Department of Systems Biology, City of Hope. We study processes within lymphocytes and those outside (in the immune microenvironment) that drive the development of lymphoid malignancies including B- and T- cell acute lymphoblastic leukemia (ALL) and lymphomas. We apply this to develop therapies that specifically target malignant lymphocytes. Research in our lab spans Hematology, Oncology, and Immuno-Oncology. The Postdoctoral Fellow who joins the team will lead a project focused on specifically targeting diseased immune subsets in systemic lupus erythematosus (SLE) and indolent lymphomas.

Application Deadline: Open Until Filled

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19. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Danilov’s group coordinates a number of Phase I/II clinical trials, thus presenting an opportunity to verify the pre-clinical hypotheses in the clinical setting and conferring immediate relevance to pre-clinical investigations. This position is created to continue research studies currently funded by the NCI R01, the Leukemia and Lymphoma Society Translational Research Program Award, MCL Research Initiative and Scholar Award. The project will match the candidate’s interests and experience.

Application Deadline: Open Until Filled

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20. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Caligiuri/Yu Laboratory at Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. We are a fast-paced lab involved in cutting-edge technology, research and clinical immunotherapy investigations. We are currently looking for a postdoctoral fellow who will develop chimeric antigen receptor T- and NK-cell therapies in combination with oncolytic viruses for the treatment of solid tumors, especially glioblastoma. The PhD candidate should have experience in the fields of immunology and cancer biology with a strong track record. This position will interact and collaborate with a team of researchers with similar interests in developing cell-based therapies in a translational research environment.

Application Deadline: Open Until Filled

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21. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Mingye Feng’s laboratory at the Beckman Research Institute of City of Hope is looking for a talented and highly motivated Postdoctoral Fellow. Dr. Feng is an awardee of the V Scholar Award from the V Foundation for Cancer Research, the Damon Runyon – Dale F. Frey Award for Breakthrough Scientists from the Damon Runyon Cancer Research Foundation, the K99/R00 Pathway to Independence Award from NIH, and NIH R01 grants. His laboratory employs cutting-edge techniques to understand mechanisms of macrophages in cancer immunosurveillance, identify immune checkpoints and ligands on various hematopoietic malignant and solider tumor cells with high-throughput screening and protein engineering approaches developed in the lab, and develop novel cancer immunotherapies targeting metastatic cancer cells.

Application Deadline: Open Until Filled

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22. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our research is focused on translational research as it relates to genomic and epigenomic characterization of various gastrointestinal cancers (GI) including colorectal, pancreatic and gastric cancers, and some of the key research topics include: 1) Development of circulating DNA/RNA-based liquid biopsy biomarkers for cancer diagnosis, prognosis and predictive response to various therapies. 2) Study the epigenetic basis of GI cancers (e.g. aberrant DNA methylation, histone modifications and non-coding RNAs. 3) The genetic basis of early-onset and familial/hereditary colorectal cancers. 4) The role of tumor microenvironment, stem cells, immune regulation and identification of novel targeted therapies. 5) The role of extracellular vesicles/exosomes as in cancer pathogenesis and their role as disease biomarkers.

Application Deadline: Open Until Filled

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23. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow Position is available in the laboratory of Dr. Tijana Jovanovic-Talisman. Biological nanoparticles that are continuously shed by cells – namely extracellular vesicles (EVs) – are an emerging and exciting strategy for performing minimally invasive diagnoses. Because EVs are loaded with disease-specific molecules, they represent an excellent source of biomarkers. The project involves employing cell biology and super-resolution microscopy approaches to characterize extracellular vesicles that contain disease-specific or tissue-specific molecules. Ultimately, the goal is to develop a new platform to perform molecular level diagnoses for precision medicine.

Application Deadline: Open Until Filled

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24. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are looking for a talented and highly motivated Postdoctoral Fellow, to join the Laboratory for Cellular Medicine (LCM), Center for Gene Therapy at the Beckman Research Institute of City of Hope. The candidate will join a well-established group performing cutting-edge research, development and qualification of large-scale processes, and manufacture of products for gene therapy clinical trials, including first-in-human studies with genetically engineered (ge) hematopoietic stem and progenitor cells (HSPC) and T cells.

Application Deadline: Open Until Filled

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25. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Nadia Carlesso’s research is focused on the mechanisms of leukemogenesis and identification of novel therapeutic approaches in poor prognosis T-ALL. Following recent laboratory discoveries, her group is exploring novel approaches to target the microenvironment/oncogene cooperation driving chemoresistance and relapse in T-ALL leukemia stem cells. This project is nested on a larger program directed by Dr. Carlesso that focuses on the relationships between the tumor microenvironment, inflammation, and stem cell biology in hematopoietic diseases. Nadia Carlesso, M.D., Ph.D. | City of Hope

Application Deadline: Open Until Filled

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26. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Ngo laboratory at the Department of Systems Biology, City of Hope is seeking a highly motivated Postdoctoral Fellow to lead a federally funded project in lymphoma and immunotherapy. Our laboratory studies molecular mechanisms and identifies therapeutic targets in hematologic malignancies. Candidates having interests in cancer biology and immunology with hands-on experience in working with hematopoietic cells and handling animals are encouraged to apply. Candidates with at least one first-author paper will be given more priority.

Application Deadline: Open Until Filled

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27. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Williams lab is looking for a highly motivated postdoctoral student interested in working in translational medicine to treat cancer. The overarching goals of the group are to identify and address unmet clinical needs (e.g., on-target, off-tissue toxicities) by rapidly translating novel molecular designs to the clinic. Using an atoms-up approach, our group pioneered the concept and development of tumor-activated IO monoclonal antibodies, leading the formation of Xilio Therapeutics which has two products currently in phase 1/2 clinical trials. We also discovered and subsequently developed a unique peptide-Fab interaction that allows us to rapidly functionalize monoclonal antibodies including antibody-drug conjugates, bispecifics including NK and T cell engagers, antibody-based imaging reagents, and switchable CAR T cells.

Application Deadline: Open Until Filled

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28. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for a highly motivated individual in the laboratory of Dr. Larry Kwak, at the Beckman Research Institute of City of Hope, a prestigious NCI-designated Comprehensive Cancer Center.

Application Deadline: Open Until Filled

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29. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Postdoctoral Fellow will work on projects with a focus on improving accessibility of cancer genomics information and integrating technology to improve health literacy. The Postdoctoral Fellow will participate in ongoing research, with a particular focus on cancer genomics, information technology innovations to improve care, cancer care delivery, data management and analysis, project coordination and management, and writing and preparation of manuscripts and grant applications. Considerable opportunities for mentored professional development including analytic skills for quantitative and qualitative data, writing lead-author papers, and designing, applying for, and conducting grant-funded research.

Application Deadline: Open Until Filled

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30. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our group is interested in discovering novel genetic and epigenetic regulations and deciphering their underlying molecular mechanisms in normal developmental processes (e.g., hematopoiesis) and tumorigenesis (e.g., leukemogenesis). We cover research areas with relevance to Hematology, Immunology, and Cancer Biology, with an emphasis on RNA epigenetics (mainly focusing on the N6 methyladenosine (m6A) modification) and DNA epigenetics (mainly focusing on the TET1/2/3-mediated DNA demethylation) associated basic and translational research. Our research involves experiments with primary human cancer cells, cancer and stem cell transplantation models, mouse genetics, classic molecular, biochemistry and cell biology, functional genomics, signal transduction, and large-scale data analysis and computational biology.

Application Deadline: Open Until Filled

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31. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. Ya-Huei Kuo, at the Beckman Research Institute of City of Hope, a prestigious NCI-designated Comprehensive Cancer Center. The candidate will directly work on identifying mechanisms contributing to leukemia pathogenesis, immune evasion and therapy resistance; developing novel leukemia therapeutics; and participate in a multidisciplinary team work to study information flow and state-transition at multi-dimensional scales.

Application Deadline: Open Until Filled

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32. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are currently seeking highly motivated and talented individuals to fill four postdoctoral positions in the laboratory of Dr. Javier Gordon Ogembo at City of Hope’s Department of Immuno-Oncology. The positions are available in the following areas (check requirements for each area at the bottom):
1. Gamma-herpesvirus vaccine development
2. Gamma-herpesvirus T cell immunology and therapeutics
3. Gamma-herpesvirus protein and antibody structural studies
4. Use of preclinical animal models to assess gamma-herpesvirus entry mechanism and vaccine development.

Application Deadline: Open Until Filled

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33. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Postdoctoral Research Fellow will explore signaling pathways relevant to drug development and discovery of basic mechanisms of cancer biology and novel therapeutic targets and epigenetic and genetic prognostic biomarkers in cancers. The fellow will be assigned projects and be responsible for designing and performing in vitro and in vivo experiments, collecting and analyzing data, writing grants, publications, and disseminating findings.

Application Deadline: Open Until Filled

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34. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow position is open in the laboratory of Yingfeng Deng in the Department of Diabetes and Cancer Metabolism at the City of Hope Beckman Research Institute. The Deng laboratory studies the homeostasis of uridine and its role in metabolism, which provides a new angle for understanding the pathophysiology of obesity, diabetes, and cancer. Work in the lab utilizes both genetically engineered mouse models and in vitro systems. A combination of state-of-the-art surgical, genetic, cellular, biochemical, imaging, and metabolic flux approaches is currently used in the lab.

Application Deadline: Open Until Filled

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35. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The candidate is expected to be an innovative scientist with knowledge and experience in molecular oncology (integrative multiomic data analysis), precision pathology (advanced Assisted image analysis on immunofluorescence-stained slides), Immunohistochemical assays and genomic profiling. Interests and knowledge in the analysis of data generated through next generation sequencing and other global technologies including transcriptomic and mutational analysis as well as correlative analysis of different datasets would be desirable. Our group works very collaboratively in a supportive and stimulatory environment with the goal of understanding the pathogenesis of DNA damage response, discovering novel therapeutic targets, and improving the treatment and outcome of women’s cancer patients.

Application Deadline: Open Until Filled

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The post 35 Postdoctoral Fellowships at City of Hope, California, USA appeared first on FellowshipBard.

1. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Williams lab is looking for a highly motivated postdoctoral student interested in working in translational medicine to treat cancer. The overarching goals of the group are to identify and address unmet clinical needs (e.g., on-target, off-tissue toxicities) by rapidly translating novel molecular designs to the clinic. Using an atoms-up approach, our group pioneered the concept and development of tumor-activated IO monoclonal antibodies, leading the formation of Xilio Therapeutics which has two products currently in phase 1/2 clinical trials.

We also discovered and subsequently developed a unique peptide-Fab interaction that allows us to rapidly functionalize monoclonal antibodies including antibody-drug conjugates, bispecifics including NK and T cell engagers, antibody-based imaging reagents, and switchable CAR T cells. Given these successes, we have broadly expanded our efforts including the discovery of novel antibodies, combining single cell techniques (enabled by the acquisition of a Berkeley Lights Beacon) with structural and computational biology efforts.

Application Deadline: Open Until Filled

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2. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr Ed Boas, at the Beckman Research Institute of City of Hope, a prestigious NCI-designated Comprehensive Cancer Center. We are looking for a biomedical engineer, materials scientist, immunologist, or cancer biologist who can help us develop new minimally invasive cancer therapies, such as new materials or devices for drug delivery into tumors (percutaneous or intra-arterial). We are one of the few interventional oncology groups in the United States with a basic science lab, large animal tumor model, and several active clinical trials, which enables us to translate new discoveries from bench to animal to bedside.

Application Deadline: Open Until Filled

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3. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow position is available in the laboratory of Edwin R. Manuel, PhD, at City of Hope, Beckman Research Center, Monrovia, CA. Our lab is interested in utilizing tumor-colonizing, bacterial-based agents as novel immunotherapy for solid and hematologic malignancies. We are recruiting enthusiastic, motivated scientists who are seeking a fast-paced academic research environment. Our lab in the Department of Immuno-Oncology focuses on engineering tumor-colonizing bacteria to target components of the tumor microenvironment that contribute poor drug delivery, immune suppression and cancer metabolism.

Application Deadline: Open Until Filled

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4. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. ZJ Sun at Beckman Research Institute of City of Hope, one of a prestigious group of NCI-designated Comprehensive Cancer Centers. The candidate will directly work on the novel and ongoing projects on prostatic stem cells and stem cell niches in prostate development and tumorigenesis using “cutting edge” and unbiased analytic tools and unique and innovative genetically engineered mouse models (please see some of the recent publications: PLoS Genet 2020 Jan 13:16(1):e1008588; Development 2021 Jan 11:148(1):dev196048; Development 2021 Oct 1:148(19):dev199738; Nat Commun 2022 Jul 28:13:4364; Nat Commun 2022 Nov 2:13:6552).

Application Deadline: Open Until Filled

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5. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the research group of Dr. Sumanta Pal, at the Beckman Research Institute and Department of Medical Oncology of City of Hope, a prestigious NCI-designated Comprehensive Cancer Center. The candidate will directly work on projects focused on genitourinary cancers, specifically kidney, bladder, and prostate cancers. This includes developing and maintaining clinical and translational research trials in genitourinary cancers, collecting, analyzing, and maintaining large databases pertaining to genitourinary cancers, drafting original research and review articles and publishing in peer reviewed journals, and developing and presenting abstracts at national and international conferences.

Application Deadline: Open Until Filled

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6. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The laboratory of Javier Gordon Ogembo, Ph.D.at The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. Our laboratory invites highly motivated candidates to apply for an interdisciplinary postdoctoral fellow position. Our laboratory focuses on oncogenic herpesviruses, in particular Epstein-Barr virus (EBV), Kaposi-sarcoma associated herpesvirus (KSHV), and the rhesus macaque EBV homologue rhesus lymphocryptovirus (rhLCV), and on developing prophylactic and therapeutic strategies against primary infection with these viruses and their associated cancers.

Application Deadline: Open Until Filled

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7. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral position is now available in the laboratory of Dr. Yilun Liu at the Department of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope. Dr. Liu’s research topics include:

• Dissecting the molecular mechanism by which transcription-associated genomic instability and epigenetic deregulation contribute to developmental abnormalities and cancer
  
• Developing pharmaceutical mechanisms for cancer therapy by targeting enzymes important for preventing the formation of DNA breaks arose during accelerated cell growth such as in cancer cells as well as factors important for the BRCA2 and PARP-dependent repair pathways to keep these DNA breaks unrepaired

Application Deadline: Open Until Filled

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8. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. June-Wha Rhee in City of Hope’s Department of Medicine, Division of Cardiology. The lab’s research focuses on understanding the biology underlying cancer therapy-induced cardiovascular complications by leveraging human-induced pluripotent stem cells (iPSCs) as well as patient samples, genomics and leading-edge computational biology.

Application Deadline: Open Until Filled

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9. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are looking for a talented and highly motivated Postdoctoral Fellow, to join the Laboratory for Cellular Medicine (LCM), Center for Gene Therapy at the Beckman Research Institute of City of Hope. The candidate will join a well-established group performing cutting-edge research, development and qualification of large-scale processes, and manufacture of products for gene therapy clinical trials, including first-in-human studies with genetically engineered (ge) hematopoietic stem and progenitor cells (HSPC) and T cells.

Application Deadline: Open Until Filled

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10. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Mingye Feng’s laboratory at the Beckman Research Institute of City of Hope is looking for a talented and highly motivated Postdoctoral Fellow. Dr. Feng is an awardee of the V Scholar Award from the V Foundation for Cancer Research, the Damon Runyon – Dale F. Frey Award for Breakthrough Scientists from the Damon Runyon Cancer Research Foundation, the K99/R00 Pathway to Independence Award from NIH, and NIH R01 grants. His laboratory employs cutting-edge techniques to understand mechanisms of macrophages in cancer immunosurveillance, identify immune checkpoints and ligands on various hematopoietic malignant and solider tumor cells with high-throughput screening and protein engineering approaches developed in the lab, and develop novel cancer immunotherapies targeting metastatic cancer cells.

Application Deadline: Open Until Filled

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11. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Wang Laboratory at the Department of Systems Biology, Beckman Research Institute, City of Hope, is seeking for a talented and motivated Postdoctoral Fellow to lead the project for RNA splicing dysregulation and oncogenesis in blood malignancies. Candidates with strong background in RNA splicing, cancer biology, animal models, and bioinformatics are encouraged to apply. Wang Laboratory is currently funded by R01 and foundation grants.

Application Deadline: Open Until Filled

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12. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Shen laboratory has been focusing on DNA replication/repair pathway components, cancer genetics and epigenetics, and cancer etiological and therapeutics modeling. The laboratory is seeking additional members to work on several new projects. Recent Ph.D. graduates or equivalents in the field of biological/medical sciences with ambition for a scientific career and interest in DNA replication and repair, genome stability, and cancer biology and skills in molecular biology, genetics or biochemistry are encouraged to apply. Bioinformatics and data mining skills are a plus for considerations.

Application Deadline: Open Until Filled

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13. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Caligiuri/Yu Laboratory at Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. We are a fast-paced lab involved in cutting-edge technology, research and clinical immunotherapy investigations. We are currently looking for a postdoctoral fellow who will develop chimeric antigen receptor T- and NK-cell therapies in combination with oncolytic viruses for the treatment of solid tumors, especially glioblastoma. The PhD candidate should have experience in the fields of immunology and cancer biology with a strong track record. This position will interact and collaborate with a team of researchers with similar interests in developing cell-based therapies in a translational research environment.

Application Deadline: Open Until Filled

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14. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Our group is interested in discovering novel genetic and epigenetic regulations and deciphering their underlying molecular mechanisms in normal developmental processes (e.g., hematopoiesis) and tumorigenesis (e.g., leukemogenesis). We cover research areas with relevance to Hematology, Immunology, and Cancer Biology, with an emphasis on RNA epigenetics (mainly focusing on the N6 methyladenosine (m6A) modification) and DNA epigenetics (mainly focusing on the TET1/2/3-mediated DNA demethylation) associated basic and translational research. Our research involves experiments with primary human cancer cells, cancer and stem cell transplantation models, mouse genetics, classic molecular, biochemistry and cell biology, functional genomics, signal transduction, and large-scale data analysis and computational biology.

Application Deadline: Open Until Filled

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15. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are seeking a talented and motivated Postdoctoral Fellow within the multidisciplinary research team headed by Drs. Nagarajan Vaidehi, Andrei S. Rodin, and Sergio Branciamore at the Department of Computational and Quantitative Medicine (chaired by Dr. Vaidehi) at the Beckman Research Institute of City of Hope. Our research group comprises computational biologists, computational chemists, and bioinformaticians, with a notable record of productivity and publishing in high-impact journals.

Application Deadline: Open Until Filled

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16. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Alexey Danilov’s research is focused on the mechanisms of lymphomagenesis and identification of novel therapeutic targets in B-cell lymphoma and other cancers. Following our recent laboratory discoveries, we also explore the immunomodulatory effects of novel targeted agents and aim to harness their potential to enhance the efficacy of immunotherapy and novel cellular therapies. We are looking for a Postdoc to advance one of the following areas of interest in our laboratory:
– immunomodulatory effects of targeted agents and mechanism-driven approaches to enhance efficacy of immune and cellular therapies;

Application Deadline: Open Until Filled

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17. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We currently have multiple Postdoctoral Fellowship positions within the multidisciplinary research team headed by Dr. Ajay Goel, Professor and Chair, Department of Molecular Diagnostics and Experimental Therapeutics and Associate Director of Basic Sciences, City of Hope Comprehensive Cancer. Our multidisciplinary research group comprises of basic biologists, gastroenterologists, surgeons, oncologists and bioinformaticians, undertaking a number of collaborative projects involving large international consortia.

Our research is focused on translational research as it relates to genomic and epigenomic characterization of various gastrointestinal cancers (GI) including colorectal, pancreatic and gastric cancers, and some of the key research topics include: 1) Development of circulating DNA/RNA-based liquid biopsy biomarkers for cancer diagnosis, prognosis and predictive response to various therapies. 2) Study the epigenetic basis of GI cancers (e.g. aberrant DNA methylation, histone modifications and non-coding RNAs. 3) The genetic basis of early-onset and familial/hereditary colorectal cancers. 4) The role of tumor microenvironment, stem cells, immune regulation and identification of novel targeted therapies. 5) The role of extracellular vesicles/exosomes as in cancer pathogenesis and their role as disease biomarkers.

Application Deadline: Open Until Filled

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18. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We are seeking a talented and motivated Postdoctoral Fellow within the multidisciplinary research team headed by Dr. Ajay Goel, Professor and Chair, Department of Molecular Diagnostics and Experimental Therapeutics and Associate Director of Basic Sciences, City of Hope Comprehensive Cancer. Our research group comprises of basic biologists, gastroenterologists, surgeons, medical oncologists and bioinformaticians, undertaking a number of collaborative projects involving large international consortia.

Application Deadline: Open Until Filled

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19. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Ngo laboratory at the Department of Systems Biology, City of Hope is seeking a highly motivated Postdoctoral Fellow to lead a federally funded project in lymphoma and immunotherapy. Our laboratory studies molecular mechanisms and identifies therapeutic targets in hematologic malignancies. Candidates having interests in cancer biology and immunology with hands-on experience in working with hematopoietic cells and handling animals are encouraged to apply. Candidates with at least one first-author paper will be given more priority.

Application Deadline: Open Until Filled

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20. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A postdoctoral fellow position in Computational Biology is immediately available under the direction of Dr. Vaidehi Nagarajan – Chair, Dept. of Computational & Quantitative Medicine at Beckman Research Institute. This project involves development and application of large scale data analysis techniques from the Systems Biology field to molecular dynamics methods, and the study of the dynamics of G-protein coupled receptors complexes to understand its signaling selectivity. The project is inter-disciplinary and provides opportunities to train in large scale data analysis techniques as well as interact with experimental collaborators. City of Hope provides a multi-disciplinary collaborative environment with opportunities to interact with clinician scientists to conduct bench side to bedside research.

Application Deadline: Open Until Filled

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21. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

We currently have a Postdoctoral Fellowship position within a research team headed by Dr. Jeff Perry, Assistant Professor, Department of Molecular Diagnostics and Experimental Therapeutics, and member of the City of Hope Comprehensive Cancer. We are looking for a post-doctoral candidate with experience in protein crystallography. A Ph.D. in Biochemistry, Biophysics or a related discipline is required. The Perry laboratory uses structural biology approaches, together with small molecule and fragment-based drug discovery, computer-aided drug discovery approaches and biochemical assays to target key proteins. This funded position is for a postdoctoral trainee interested in aiding the development of therapeutic against both type 1 and type 2 diabetes mellitus.

Application Deadline: Open Until Filled

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22. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Postdoctoral Fellow position is available immediately in the laboratory of Dr. Christiane Querfeld, M.D., Ph.D. at Beckman Research Institute of City of Hope. Christiane Querfeld, M.D., Ph.D., director of the Cutaneous Lymphoma Program, seeks better treatment options for cutaneous T cell lymphoma (CTCL), a rare form of lymphoma that first appears on the skin but can also spread to lymph nodes and internal organs. City of Hope is one of the few institutions in the country that offers clinical trials to treat cutaneous lymphomas. Dr. Querfeld leads a multidisciplinary team of experts, including medical and radiation oncologists, pioneering treatments for CTCL and its subtypes.

Application Deadline: Open Until Filled

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23. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Postdoctoral positions are now available in the laboratory of Dr. Yilun Liu at the Department of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope. Dr. Liu’s research topics include:

• Dissecting the molecular mechanism by which transcription-associated genomic instability and epigenetic deregulation contribute to developmental abnormalities and cancer.
  
• Developing pharmaceutical mechanisms for cancer therapy by targeting enzymes important for preventing the formation of DNA breaks arose during accelerated cell growth such as in cancer cells as well as factors important for the BRCA2 and PARP-dependent repair pathways to keep these DNA breaks unrepaired.

Application Deadline: Open Until Filled

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24. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Join our successful and productive research team at the Beckman Research Institute at City of Hope where we are studying the biological mechanisms of breast cancer susceptibility in the context of aging. This current position is focused on using cell and molecular techniques to examine emergent mechanical properties of epithelial cells that are highly susceptible to breast cancer initiation.

This mechanobiology work is the product of a long-term, NIH funded, collaboration with a bioengineering group at UC Berkeley. We are using, and evolving, a mechano-node pore sensing (mechano-NPS) platform to explore unique mechanical properties of cells that are associated with chronological or biological age, lineage, and cancer progression stage. We hypothesized that mechano-NPS can detect disease states based on the emergent mechanical properties that arise from the underlying molecular networks that define lineage and disease states.

Application Deadline: Open Until Filled

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25. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. The Williams Research Team seeks a self-motivated, results-driven postdoc to drive the development of the generation of therapeutic monoclonal antibodies. Expertise required include thorough knowledge of protein engineering (cloning, expression, purification), crystallography (crystallization, optimization, data collection and structure determination), biochemistry (enzyme kinetics) and biophysics (Surface Plasmon Resonance, Iosthermal Ttitration Calorimetry, etc).

Application Deadline: Open Until Filled

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26. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Nadia Carlesso’s research is focused on the mechanisms of leukemogenesis and identification of novel therapeutic approaches in poor prognosis T-ALL. Following recent laboratory discoveries, her group is exploring novel approaches to target the microenvironment/oncogene cooperation driving chemoresistance and relapse in T-ALL leukemia stem cells. This project is nested on a larger program directed by Dr. Carlesso that focuses on the relationships between the tumor microenvironment, inflammation, and stem cell biology in hematopoietic diseases.

Application Deadline: Open Until Filled

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27. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow Position is available in the laboratory of Dr. Tijana Jovanovic-Talisman. Biological nanoparticles that are continuously shed by cells – namely extracellular vesicles (EVs) – are an emerging and exciting strategy for performing minimally invasive diagnoses. Because EVs are loaded with disease-specific molecules, they represent an excellent source of biomarkers. The project involves employing cell biology and super-resolution microscopy approaches to characterize extracellular vesicles that contain disease-specific or tissue-specific molecules. Ultimately, the goal is to develop a new platform to perform molecular level diagnoses for precision medicine.

Application Deadline: Open Until Filled

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28. Postdoctoral Position 

Summary of Postdoctoral Fellowship:

Dr. Yanhong Shi’s lab is looking for highly motivated and productive postdoctoral fellows for stem cell research projects within the Department of Stem Cell Biology and Regenerative Medicine (Shi laboratory) at Beckman Research Institute of City of Hope located in the county of Los Angeles, California. Candidates interested in this position are encouraged to submit curriculum vitae, brief statement of interests and a list of three references. The Shi laboratory has been well known for stem cell research, including stem cell-based disease modeling and cell therapy development. This laboratory is one of the pioneers in establishing disease models and cell therapies using the human induced pluripotent stem cell (iPSC) platform and has published extensively in this area.

Application Deadline: Open Until Filled

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The post 28 Postdoctoral Fellowships at City of Hope, California, United States appeared first on FellowshipBard.

1. Postdoctoral Position in T Cell Therapeutics

Summary of Postdoctoral Fellowship:

The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. The T Cell Therapeutics Research Laboratory (TCTRL) overseen by Stephen Forman, M.D., is a fast-paced lab involved in cutting edge technology, research and clinical immunotherapeutic programs. The TCTRL currently has an opening for a postdoctoral fellow who will develop chimeric antigen receptor T cell therapies. The postdoctoral candidate will ideally have experience in the fields of viral specific T cells and HIV. This position will interact and collaborate with a team of research scientists with similar interests in developing T cell therapies.

Application Deadline: Open Until Filled

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2. Postdoctoral Position in Metabolism in Thermogenic Brown Adipocytes

Summary of Postdoctoral Fellowship:

The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow to join the Arthur Riggs Diabetes and Metabolism Research Institute – Department of Molecular and Cellular Endocrinology. Dr. Lei Jiang’s laboratory focuses on the molecular mechanisms regulating central carbon metabolism in adipocytes and lung cancer cells. The application of mathematical- and bioengineering-based modeling prediction and experimental mass spec-based metabolic tracing will provide a better understanding of metabolic rewiring in obesity and cancer. A determined and self-motivated postdoc is encouraged to join Dr. Jiang’s laboratory, to focus on an ongoing study of the fuel metabolism in thermogenic brown adipocytes.

Application Deadline: Open Until Filled

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3. Postdoctoral Position in Immunology and Cancer Therapy Development

Summary of Postdoctoral Fellowship:

We are recruiting enthusiastic, motivated scientists who are seeking a fast-paced, team-based academic research environment. Our lab in the Department of Immuno-oncology focuses on how blood and immune cells develop, function, and interact with other cells, with a second focus on how blood stem cells become malignant. We use mass spectrometry to identify activated protein circuits in rare blood stem and progenitor cell populations, including therapeutic chimeric antigen receptor (CAR) T cells, and combine that knowledge with fundamental immunological principles to improve and devise new therapies for pediatric cancers and blood disorders.

Application Deadline: Open Until Filled

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4. Postdoctoral Position in Precision Oncology of Gastrointestinal Cancers

Summary of Postdoctoral Fellowship:

We currently have multiple Postdoctoral Fellowship positions within the multidisciplinary research team headed by Dr. Ajay Goel, Professor and Chair, Department of Molecular Diagnostics and Experimental Therapeutics and Associate Director of Basic Sciences, City of Hope Comprehensive Cancer. Our multidisciplinary research group comprises of basic biologists, gastroenterologists, surgeons, oncologists and bioinformaticians, undertaking a number of collaborative projects involving large international consortia. Our research is focused on translational research as it relates to genomic and epigenomic characterization of various gastrointestinal cancers (GI) including colorectal, pancreatic and gastric cancers.

Application Deadline: Open Until Filled

More Details

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5. Postdoctoral Position in Cell Biology and Quantitative Microscopy

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow Position is available in the laboratory of Dr. Tijana Jovanovic-Talisman. Biological nanoparticles that are continuously shed by cells – namely extracellular vesicles (EVs) – are an emerging and exciting strategy for performing minimally invasive diagnoses. Because EVs are loaded with disease-specific molecules, they represent an excellent source of biomarkers. The project involves employing cell biology and super-resolution microscopy approaches to characterize extracellular vesicles that contain disease-specific or tissue-specific molecules. Ultimately, the goal is to develop a new platform to perform molecular level diagnoses for precision medicine.

Application Deadline: Open Until Filled

More Details

6. Postdoctoral Position in Computational Biology, Biostatistics and Bioinformatics

Summary of Postdoctoral Fellowship:

Our research is focused on translational research as it relates to genomic and epigenomic characterization of various gastrointestinal cancers (GI) including colorectal, pancreatic and gastric cancers, and some of the key research topics include: 1) Development of circulating DNA/RNA-based liquid biopsy biomarkers for cancer diagnosis, prognosis and predictive response to various therapies. 2) Study the epigenetic basis of GI cancers (e.g. aberrant DNA methylation, histone modifications and non-coding RNAs. 3) The genetic basis of early-onset and familial/hereditary colorectal cancers.

Application Deadline: Open Until Filled

More Details

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7. Postdoctoral Position in Molecular Pathogenesis of Lymphoid Malignancies

Summary of Postdoctoral Fellowship:

The Ngo laboratory at the Department of Systems Biology, City of Hope is seeking a highly motivated Postdoctoral Fellow to lead a federally funded project in lymphoma and immunotherapy. Our laboratory studies molecular mechanisms and identifies therapeutic targets in hematologic malignancies. Candidates having interests in cancer biology and immunology with hands-on experience in working with hematopoietic cells and handling animals are encouraged to apply. Candidates with at least one first-author paper will be given more priority.

Application Deadline: Open Until Filled

More Details

8. Postdoctoral Position in Hematology, Immunology, and Cancer Biology

Summary of Postdoctoral Fellowship:

Our group is interested in discovering novel genetic and epigenetic regulations and deciphering their underlying molecular mechanisms in normal developmental processes (e.g., hematopoiesis) and tumorigenesis (e.g., leukemogenesis). We cover research areas with relevance to Hematology, Immunology, and Cancer Biology, with an emphasis on RNA epigenetics (mainly focusing on the N6 methyladenosine (m6A) modification) and DNA epigenetics (mainly focusing on the TET1/2/3-mediated DNA demethylation) associated basic and translational research.

Application Deadline: Open Until Filled

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9. Postdoctoral Position in Lymphoma Genomics and Biology

Summary of Postdoctoral Fellowship:

The department of pathology of the City of Hope Medical center is recruiting a postdoctoral fellow to work with a group of researchers in lymphoma genomics and biology. The candidate is expected to be an innovative scientist with knowledge and experience in molecular biology, cell culture, in vitro functional assays and genomic editing. Some interests and knowledge in the analysis of data generated through next generation sequencing and other global technologies including transcriptomic and mutational analysis as well as correlative analysis of different datasets would be desirable.

Application Deadline: Open Until Filled

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10. Postdoctoral Position in Cancer Immunosurveillance and Immunotherapy

Summary of Postdoctoral Fellowship:

Dr. Mingye Feng’s laboratory at the Beckman Research Institute of City of Hope is looking for a talented and highly motivated Postdoctoral Fellow. Dr. Feng is an awardee of the V Scholar Award from the V Foundation for Cancer Research, the Damon Runyon – Dale F. Frey Award for Breakthrough Scientists from the Damon Runyon Cancer Research Foundation, the K99/R00 Pathway to Independence Award from NIH, and NIH R01 grants. His laboratory employs cutting-edge techniques to understand mechanisms of macrophages in cancer immunosurveillance, identify immune checkpoints and ligands on various hematopoietic malignant and solider tumor cells with high-throughput screening and protein engineering approaches developed in the lab, and develop novel cancer immunotherapies targeting metastatic cancer cells.

Application Deadline: Open Until Filled

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11. Postdoctoral Position in Hematology & Hematopoietic Cell Transplantation

Summary of Postdoctoral Fellowship:

The Caligiuri/Yu Laboratory at Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. We are a fast-paced lab involved in cutting-edge technology, research and clinical immunotherapy investigations. We are currently looking for a postdoctoral fellow who will develop chimeric antigen receptor T- and NK-cell therapies in combination with oncolytic viruses for the treatment of solid tumors, especially glioblastoma. The PhD candidate should have experience in the fields of immunology and cancer biology with a strong track record. This position will interact and collaborate with a team of researchers with similar interests in developing cell-based therapies in a translational research environment.

Application Deadline: Open Until Filled

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12. Postdoctoral Position in DNA Replication and Repair

Summary of Postdoctoral Fellowship:

The Shen laboratory has been focusing on DNA replication/repair pathway components, cancer genetics and epigenetics, and cancer etiological and therapeutics modeling. Recent Ph.D. graduates or equivalents in the field of biological/medical sciences with ambition for a scientific career and interest in DNA repair and cancer biology and skills in molecular biology are encouraged to apply. Bioinformatics and database mining skills are a plus.

Application Deadline: Open Until Filled

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13. Postdoctoral Position in Biochemistry and Cell Biology

Summary of Postdoctoral Fellowship:

A Postdoctoral position is now available in the laboratory of Dr. Yilun Liu at the Department of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope. Dr. Liu’s research topics include: Dissecting the molecular mechanism by which transcription-associated genomic instability and epigenetic deregulation contribute to developmental abnormalities and cancer. Developing pharmaceutical mechanisms for cancer therapy by targeting enzymes important for preventing the formation of DNA breaks arose during accelerated cell growth such as in cancer cells as well as factors important for the BRCA2 and PARP-dependent repair pathways to keep these DNA breaks unrepaired.

Application Deadline: Open Until Filled

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14. Postdoctoral Position in Cancer Genetics and Epigenetics

Summary of Postdoctoral Fellowship:

Dr. David Chen’s research group at the Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. Dr. Chen is the Director of Division of Epigenetics and Transcriptional Engineering at City of Hope. His lab focuses on epigenetic mechanisms, drug resistance, and therapeutic target discovery in cancers using high throughput genetic screens. This laboratory is skilled in high-throughput CRISPR genetic screens for de novo therapeutic target discovery. They also utilize next-generation sequencing (NGS) for epigenomic and transcriptomic analyses (ChIPseq, ATACseq, RNAseq, etc.), and the patient-derived xenograft (PDX) models for in vivo therapeutic efficacy assessments.

Application Deadline: Open Until Filled

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15. Postdoctoral Position in Herpesvirus Vaccine Development

Summary of Postdoctoral Fellowship:

Our laboratory invites highly motivated candidates to apply for an interdisciplinary postdoctoral scholar position. Our laboratory focuses on oncogenic herpesviruses, in particular Epstein-Barr virus (EBV), Kaposi-sarcoma associated herpesvirus (KSHV), and the rhesus macaque EBV homologue rhesus lymphocryptovirus (rhLCV), and on developing prophylactic and therapeutic strategies against primary infection with these viruses and their associated cancers. The postdoctoral scholar will be working on projects with the overarching goal of designing and testing gamma herpesvirus vaccine candidates and immuno-therapeutics in various preclinical animal models.

Application Deadline: Open Until Filled

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16. Postdoctoral Position in Hematologic Malignancies

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow position is available in the Vaccine Research Laboratory of Dr Don J Diamond in the Department of Hematology & Hematopoietic Cell Transplantation of the City of Hope. Dr Diamond’s research team is seeking a highly motivated candidate with experience in molecular biology/virology or viral immunology. The position is available as part of multiple research projects to develop COVID-19 and CMV vaccines based on a highly efficient and fully synthetic viral-vectored vaccine platform for pathogen preparedness and disease prevention.

Application Deadline: Open Until Filled

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17. Postdoctoral Position in Cancer Biology

Summary of Postdoctoral Fellowship:

The Wang Laboratory at the Department of Systems Biology, Beckman Research Institute, City of Hope, is seeking for a talented and motivated Postdoctoral Fellow to lead the project for RNA splicing dysregulation, DNA damage response, and oncogenesis in blood malignancies. Candidates with strong background in RNA splicing, DNA damage, cancer biology, animal models, and bioinformatics are encouraged to apply. Wang Laboratory is currently funded by two R01 grants, foundation grants, and City of Hope Startup package.

Application Deadline: Open Until Filled

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18. Postdoctoral Position in Lymphoma Research

Summary of Postdoctoral Fellowship:

Dr. Alexey Danilov’s research is focused on the mechanisms of lymphomagenesis and identification of novel therapeutic targets in B-cell lymphoma and other cancers. Following our recent laboratory discoveries, we also explore the immunomodulatory effects of novel targeted agents and aim to harness their potential to enhance the efficacy of immunotherapy and novel cellular therapies.

Application Deadline: Open Until Filled

More Details

19. Postdoctoral Position in Translational Medicine

Summary of Postdoctoral Fellowship:

The Williams lab is looking for a highly motivated postdoctoral student interested in working in translational medicine to treat cancer. The overarching goals of the group are to identify and address unmet clinical needs (e.g., on-target, off-tissue toxicities) by rapidly translating novel molecular designs to the clinic. Using an atoms-up approach, our group pioneered the concept and development of tumor-activated IO monoclonal antibodies, leading the formation of Xilio Therapeutics which has two products currently in phase 1/2 clinical trials.

Application Deadline: Open Until Filled

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20. Postdoctoral Position in Ovarian Cancer

Summary of Postdoctoral Fellowship:

The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow for translational research in the field of cancer biology and therapy. Ongoing studies are focusing on targeting ovarian cancer tumor microenvironment by conditionally replicative oncolytic virus and development of new agents targeting extrinsic and intrinsic apoptotic pathways.

Application Deadline: Open Until Filled

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21. Postdoctoral Position in Precision Oncology of Gastrointestinal Cancers

Summary of Postdoctoral Fellowship:

We are seeking multiple Staff Scientists to become a part of the multidisciplinary research team headed by Dr. Ajay Goel, Professor and Chair, Department of Molecular Diagnostics and Experimental Therapeutics. Our research group comprises of basic biologists, gastroenterologists, surgeons, medical oncologists and bioinformaticians, undertaking a number of collaborative projects involving large international consortia. Our research is focused on translational research as it relates to genomic and epigenomic characterization of various gastrointestinal cancers (GI) including colorectal, pancreatic and gastric cancers.

Application Deadline: Open Until Filled

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22. Postdoctoral Position in Cutaneous T cell Lymphoma

Summary of Postdoctoral Fellowship:

Dr. Querfeld’s laboratory investigations are focused on the microenvironment in CTCL funded by NIH-NCI R01 and LLS scholar grants. She has demonstrated that cancer growth is fostered by the surrounding nonmalignant cells. These observations have led to the initiation of several targeted and immunologic therapies to restore the immune system and hereby killing the cancerous cells. Examples include a microRNA (miR155) antagomir that inhibits proliferation, an anti-CD47 construct enhancing macrophage killing and a randomized investigator initiated trial comparing the checkpoint inhibitor anti-PD-L1 with/without the immunomodulatory drug lenalidomide.

Application Deadline: Open Until Filled

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23. Postdoctoral Position in Computational Approaches in Cancer Biology and Genomics

Summary of Postdoctoral Fellowship:

One full-time postdoc position is available at Dr. Yun Rose Li’s laboratory at Beckman Research Institute, City of Hope. Dr. Li is a physician scientist in radiation oncology whose research integrates genetic epidemiology, innovative sequencing and bioinformatics technologies, molecular biology approaches using cell-based and animal models, and biomarker studies from patients enrolled in clinical trials to better understand the role of oxidative stress in cancer risk and treatment response. The prospective candidates should be highly self-motivated, creative, and capable of working independently and in a team.

Application Deadline: Open Until Filled

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24. Postdoctoral Position in Protein Engineering in T Cell Therapeutics Research

Summary of Postdoctoral Fellowship:

The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. The T Cell Therapeutics Research Laboratory (TCTRL) overseen by Stephen Forman, M.D., is a fast-paced lab involved in cutting edge technology, research and clinical immunotherapeutic programs. The TCTRL currently has an opening for a postdoctoral fellow who will develop chimeric antigen receptor T cell therapies and other immunotherapies for the treatment of cancer. The postdoctoral candidate will ideally have expertise in the field of protein engineering, particularly with experience engineering antibodies or other binding moieties. Experience with yeast surface display or other display technologies (e.g. phage display, ribosome display, etc.) is required.

Application Deadline: Open Until Filled

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25. Postdoctoral Position in Immunotherapy for Solid and Hematologic Malignancies

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow position is available in the laboratory of Edwin R. Manuel, PhD, at City of Hope, Beckman Research Center, Monrovia, CA. Our lab is interested in utilizing tumor-colonizing, bacterial-based agents as novel immunotherapy for solid and hematologic malignancies. We are recruiting enthusiastic, motivated scientists who are seeking a fast-paced academic research environment. Our lab in the Department of Immuno-Oncology focuses on engineering tumor-colonizing bacteria to target components of the tumor microenvironment that contribute poor drug delivery, immune suppression and cancer metabolism.

Application Deadline: Open Until Filled

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26. Postdoctoral Position in Protein Chemistry, Crystallography and Structure Determination

Summary of Postdoctoral Fellowship:

The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. The Williams Research Team seeks a self-motivated, results-driven postdoc to drive the development of the generation of therapeutic monoclonal antibodies. Expertise required include thorough knowledge of protein engineering (cloning, expression, purification), crystallography (crystallization, optimization, data collection and structure determination), biochemistry (enzyme kinetics) and biophysics (Surface Plasmon Resonance, Iosthermal Ttitration Calorimetry, etc).

Application Deadline: Open Until Filled

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27. Postdoctoral Position in Biological Mechanisms of Breast Cancer Susceptibility

Summary of Postdoctoral Fellowship:

Join our successful and productive research team at the Beckman Research Institute at City of Hope where we are studying the biological mechanisms of breast cancer susceptibility in the context of aging. This current position is focused on using cell and molecular techniques to examine emergent mechanical properties of epithelial cells that are highly susceptible to breast cancer initiation. This mechanobiology work is the product of a long-term, NIH funded, collaboration with a bioengineering group at UC Berkeley. We are using, and evolving, a mechano-node pore sensing (mechano-NPS) platform to explore unique mechanical properties of cells that are associated with chronological or biological age, lineage, and cancer progression stage.

Application Deadline: Open Until Filled

More Details

28. Postdoctoral Position in COVID-19 and CMV Vaccines Development

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow position is available in the Vaccine Research Laboratory of Dr. Don Diamond in the Department of Hematology & Hematopoietic Cell Transplantation of the City of Hope. Dr. Diamond’s research team is seeking a highly motivated candidate with experience in molecular biology/virology or viral immunology. The position is available as part of multi-disciplinary research projects to develop COVID-19 and CMV vaccines based on a highly efficient and fully synthetic poxvirus-vectored vaccine platform for pathogen preparedness and infectious disease prevention.

Application Deadline: Open Until Filled

More Details

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29. Postdoctoral Position in COVID-19 and CMV Vaccines Development

Summary of Postdoctoral Fellowship:

A Postdoctoral Fellow position is available in the Vaccine Research Laboratory of Dr. Don Diamond in the Department of Hematology & Hematopoietic Cell Transplantation of the City of Hope. Dr. Diamond’s research team is seeking a highly motivated candidate with experience in molecular biology/virology or viral immunology. The position is available as part of multi-disciplinary research projects to develop COVID-19 and CMV vaccines based on a highly efficient and fully synthetic poxvirus-vectored vaccine platform for pathogen preparedness and infectious disease prevention.

Application Deadline: Open Until Filled

More Details

30. Postdoctoral Position in CRISPR Genetic Screens and Functional Epigenetics

Summary of Postdoctoral Fellowship:

Dr. David Chen’s research group at the Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. Dr. Chen is the Director of Division of Epigenetics and Transcriptional Engineering at City of Hope. His lab focuses on epigenetic mechanisms, drug resistance, and therapeutic target discovery in cancers using high throughput genetic screens. This laboratory is skilled in high-throughput CRISPR genetic screens for de novo therapeutic target discovery. They also utilize next-generation sequencing (NGS) for epigenomic and transcriptomic analyses (ChIPseq, ATACseq, RNAseq, etc.), and the patient-derived xenograft (PDX) models for in vivo therapeutic efficacy assessments.

Application Deadline: Open Until Filled

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31. Postdoctoral Position in Developmental and Stem Cell Biology

Summary of Postdoctoral Fellowship:

The Shi laboratory has been well known for stem cell research, including stem cell-based disease modeling and cell therapy development. This laboratory is one of the pioneers in establishing disease models and cell therapies using the human induced pluripotent stem cell (iPSC) platform and has published extensively in this area. Some of the papers published by the Shi laboratories include Shi et al. Nature Reviews Drug Discovery 16: 115-130, 2017; Li et al. Cell Stem Cell 23: 239-251, 2018; Feng et al. Advanced Science 7: 2002155, 2020; Wang, et al. Cell Stem Cell 28: 331-342.e5, 2021; Chen et al. Advanced Science: 8: e2101462, 2021; Cui et al. Nature Cancer 2: 932-949, 2021.

Application Deadline: Open Until Filled

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The post 31 Postdoctoral Fellowships at City of Hope, California, USA appeared first on FellowshipBard.

1. Postdoctoral Position in Translational Research & Cellular Therapeutics

Summary of Postdoctoral Fellowship:

We believe diversity, equity and inclusion is key in serving our mission to provide compassionate patient care, drive innovative discovery, and advance vital education focused on eliminating cancer and diabetes in all of our communities. Our commitment to Diversity, Equity and Inclusion ensures we bring the full range of skills, perspectives, cultural backgrounds and experiences to our work — and that our teams align with the people we serve in order to build trust and understanding.

Application Deadline: Open Until Filled

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2. Associate Research Professor- Bioinformatics

Summary of Postdoctoral Fellowship:

The department of Surgery at Beckman Research Institute of City of Hope has an opening for an Associate Professor. Basic education, experience and skills required for consideration: PhD degree biological sciences or related field and have a demonstrable record of accomplishments, peer-reviewed publications and extramural funding in related research.

Application Deadline: Open Until Filled

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3. Postdoctoral Position in Hematology

Summary of Postdoctoral Fellowship:

Our group is interested in discovering novel genetic and epigenetic regulations and deciphering their underlying molecular mechanisms in normal developmental processes (e.g., hematopoiesis) and tumorigenesis (e.g., leukemogenesis). We cover research areas with relevance to Hematology, Immunology, and Cancer Biology, with an emphasis on RNA epigenetics (mainly focusing on the N6 methyladenosine (m6A) modification) and DNA epigenetics (mainly focusing on the TET1/2/3-mediated DNA demethylation) associated basic and translational research.

Our research involves experiments with primary human cancer cells, cancer and stem cell transplantation models, mouse genetics, classic molecular, biochemistry and cell biology, functional genomics, signal transduction, and large-scale data analysis and computational biology.

Application Deadline: Open Until Filled

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4. Postdoctoral Position in Cell Biology and Quantitative Microscopy

Summary of Postdoctoral Fellowship:

An NIH-funded Postdoctoral Fellow Position is available to probe the mechanisms of alcohol use disorders. In the U.S., this brain disorder is estimated to occur in 15 million people. The resulting pattern of long-term alcohol use can lead to cancer and diabetes; it may limit the life span of an individual by more than 20 years. Unfortunately, the scarce therapies that exist for treating alcohol use disorders are marginally effective. One challenge in developing new treatments has been that alcohol does not bind to specific receptors.

Rather, it perturbs the dynamics of protein-lipid interactions in the plasma membrane. To identify potential new therapeutic approaches, our laboratory has been probing the disorder at the molecular level. Using single molecule localization microscopy in cultured cells and rat brain slices, our goal is to define the nano-organization of kappa opioid receptor, mu opioid receptor, and relevant components of the plasma membrane. We expect this molecular level data to open avenues towards new treatments for alcohol use disorders.

Application Deadline: Open Until Filled

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5. Postdoctoral Position in Biochemistry and Cell Biology

Summary of Postdoctoral Fellowship:

A Postdoctoral position is now available in the laboratory of Dr. Yilun Liu at the Department of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope. Dr. Liu’s research topics include: Dissecting the molecular mechanism by which transcription-associated genomic instability and epigenetic deregulation contribute to developmental abnormalities and cancer.

Developing pharmaceutical mechanisms for cancer therapy by targeting enzymes important for preventing the formation of DNA breaks arose during accelerated cell growth such as in cancer cells as well as factors important for the BRCA2 and PARP-dependent repair pathways to keep these DNA breaks unrepaired.

Application Deadline: Open Until Filled

More Details

6. Postdoctoral Position in Translational Medicine

Summary of Postdoctoral Fellowship:

The Williams lab is looking for a highly motivated postdoctoral student interested in working in translational medicine to treat cancer. The overarching goals of the group are to identify and address unmet clinical needs (e.g., on-target, off-tissue toxicities) by rapidly translating novel molecular designs to the clinic. Using an atoms-up approach, our group pioneered the concept and development of tumor-activated IO monoclonal antibodies, leading the formation of Xilio Therapeutics which has two products currently in phase 1/2 clinical trials.

We also discovered and subsequently developed a unique peptide-Fab interaction that allows us to rapidly functionalize monoclonal antibodies including antibody-drug conjugates, bispecifics including NK and T cell engagers, antibody-based imaging reagents, and switchable CAR T cells. Given these successes, we have broadly expanded our efforts including the discovery of novel antibodies, combining single cell techniques (enabled by the acquisition of a Berkeley Lights Beacon) with structural and computational biology efforts.

Application Deadline: Open Until Filled

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7. Staff Scientist in CAR T Cell Therapy

Summary of Postdoctoral Fellowship:

The T Cell Immunotherapy Program at City of Hope is a fast-paced lab involved in cutting-edge technology, research and clinical immunotherapy studies. We are currently looking for a staff scientist who will be a part of a translational science and product development team for our allogeneic iPSC CAR T project.

Application Deadline: Open Until Filled

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8. Assistant Research Professor in Radiology Oncology and Surgery

Summary of Postdoctoral Fellowship:

City of Hope is recruiting an experienced statistician for a non‐tenure track faculty appointment to support clinical trials in the Departments of Radiation Oncology and Surgery. This will be a joint appointment in Radiology Oncology/Surgery and Biostatistics in the Research Professor series, at a rank consistent with qualifications and experience. The candidate selected for this position will report to the Director of Biostatistics.

Application Deadline: Open Until Filled

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9. Assistant Research Professor in Molecular and Cellular Endocrinology

Summary of Postdoctoral Fellowship:

The department of Molecular and Cellular Endocrinology at Beckman Research Institute of City of Hope has an opening for an Assistant Research Professor. PhD degree in biological sciences or related field and have a demonstrable record of accomplishments, peer-reviewed publications and record of extramural funding at any level preferred, but not required.

Application Deadline: Open Until Filled

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10. Staff Scientist in Diabetes Immunology

Summary of Postdoctoral Fellowship:

A Staff Scientist position is available in Beckman Research Institute of City of Hope. The Staff Scientist series is designed for career research professionals whose primary function is to support the research infrastructure and activities of the institution. Staff Scientists will bring special skills, knowledge and experience to research programs or institutional core laboratories. Individuals appointed as staff scientists will receive a one-year fixed-term contract.

Application Deadline: Open Until Filled

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